ARGS / Argos Therapeutics, Inc. - Документы SEC, Годовой отчет, Доверенное заявление

Аргос Терапевтикс, Инк.
US ˙ OTC
ЭТОТ СИМВОЛ БОЛЬШЕ НЕ АКТИВЕН

Основная статистика
CIK 1105533
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Argos Therapeutics, Inc.
SEC Filings (Chronological Order)
На этой странице представлен полный хронологический список документов SEC, за исключением документов о собственности, которые мы предоставляем в других местах.
May 3, 2019 8-K

Financial Statements and Exhibits, Changes in Registrant's Certifying Accountant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 1, 2019 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporation) (Commission Fi

May 3, 2019 EX-16.1

Letter from PricewaterhouseCoopers LLP to the SEC, dated May 3, 2019, regarding the statements made in this Current Report on Form 8-K

Exhibit 16.1 May 3, 2019 Securities and Exchange Commission 100 F Street, N.E. Washington, DC 20549 Commissioners: We have read the statements made by Argos Therapeutics, Inc. (copy attached), which we understand will be filed with the Securities and Exchange Commission, pursuant to Item 4.01 of Form 8-K of Argos Therapeutics, Inc. dated May 1, 2019. We agree with the statements concerning our Fir

February 14, 2019 SC 13D/A

ARGS / Argos Therapeutics, Inc. / ForArgos B.V. - SC 13D/A Activist Investment

SC 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13D UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 2)* ARGOS THERAPEUTICS INC. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 040221 103 (CUSIP Number) ForArgos B.V. Gooimeer 2-35, 1411 DC Naarden The Netherlands (Name, Address and Telephone Number of Person

February 14, 2019 EX-99.2

Shareholders’ Agreement January 27, 2016 ForArgos B.V. by and among Coöperatieve AAC LS U.A. Forbion Co-Investment II Coöperatief U.A. Forbion CF II Co-Invest I Coöperatief U.A.

EX-99.2 Exhibit 99.2 Shareholders’ Agreement January 27, 2016 ForArgos B.V. by and among Coöperatieve AAC LS U.A. and Forbion Co-Investment II Coöperatief U.A. and Forbion CF II Co-Invest I Coöperatief U.A. FORARGOS B.V. (“ForArgos”) is a private company with limited liability incorporated under the laws of the Netherlands (besloten vennootschap met beperkte aansprakelijkheid) on January 27, 2016.

February 14, 2019 EX-99.1

Joint Filing Agreement

EX-99.1 CUSIP No. 040221 103 Exhibit 99.1 Joint Filing Agreement In accordance with Rule 13d-1(f) under the Securities and Exchange Act of 1934, the persons or entities named below agree to the joint filing on behalf of each of them of a statement on Schedule 13D (including amendments thereto) with respect to the Shares of the Issuer and further agree that this joint filing agreement be included a

December 3, 2018 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Bankruptcy or Receivership

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 29, 2018 Argos Therapeutics, Inc.

November 19, 2018 EX-10.6

Release of Claims Agreement, dated July 20, 2018, by and between the Registrant and Charles Nicolette

Exhibit 10.6 RELEASE OF CLAIMS AGREEMENT In exchange for the consideration set forth in the Retention Agreement dated July 20, 2018 (the “Retention Agreement”) to which this Release of Claims Agreement (the “Release Agreement”) is attached as Exhibit A, including receipt of the Initial Retention Amount (as defined therein) and eligibility to receive the Temporary Revised Salary Amount and Second R

November 19, 2018 EX-10.8

Consulting Agreement, dated August 29, 2018, by and between the Registrant and Richard Katz

Exhibit 10.8 ARGOS THERAPEUTICS, INC. CONSULTING AGREEMENT This Consulting Agreement (this “Agreement”) is entered into as of August 29, 2018 (the “Effective Date”) by and between Argos Therapeutics, Inc. (the “Company”), and Richard Katz (the “Consultant”). WHEREAS, the Consultant has certain knowledge and expertise regarding the Company as a result of having served as its Vice President and Chie

November 19, 2018 EX-10.4

Release of Claims Agreement, dated July 20, 2018, by and between the Registrant and Jeffrey D. Abbey

Exhibit 10.4 RELEASE OF CLAIMS AGREEMENT In exchange for the consideration set forth in the Retention Agreement dated July 20, 2018 (the “Retention Agreement”) to which this Release of Claims Agreement (the “Release Agreement”) is attached as Exhibit A, including receipt of the Initial Retention Amount (as defined therein) and eligibility to receive the Temporary Revised Salary Amount and Second R

November 19, 2018 EX-10.5

Release of Claims Agreement, dated July 20, 2018, by and between the Registrant and Richard Katz

Exhibit 10.5 RELEASE OF CLAIMS AGREEMENT In exchange for the consideration set forth in the Retention Agreement dated July 20, 2018 (the “Retention Agreement”) to which this Release of Claims Agreement (the “Release Agreement”) is attached as Exhibit A, including receipt of the Initial Retention Amount (as defined therein) and eligibility to receive the Temporary Revised Salary Amount and Second R

November 19, 2018 EX-10.7

Consulting Agreement, dated August 29, 2018, by and between the Registrant and Jeffrey D. Abbey

EX-10.7 8 exh107.htm EXHIBIT 10.7 Exhibit 10.7 ARGOS THERAPEUTICS, INC. CONSULTING AGREEMENT This Consulting Agreement (this “Agreement”) is entered into as of August 29, 2018 (the “Effective Date”) by and between Argos Therapeutics, Inc. (the “Company”), and Jeffrey Abbey (the “Consultant”). WHEREAS, the Consultant has certain knowledge and expertise regarding the Company as a result of having se

November 19, 2018 10-Q

ARGS / Argos Therapeutics, Inc. FORM 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2018 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS THERAPEUTICS, INC. (Exact name of

November 19, 2018 EX-10.9

Consulting Agreement, dated August 29, 2018, by and between the Registrant and Charles Nicolette

Exhibit 10.9 ARGOS THERAPEUTICS, INC. CONSULTING AGREEMENT This Consulting Agreement (this “Agreement”) is entered into as of August 29, 2018 (the “Effective Date”) by and between Argos Therapeutics, Inc. (the “Company”), and Charles Nicolette (the “Consultant”). WHEREAS, the Consultant has certain knowledge and expertise regarding the Company as a result of having served as its Vice President of

November 19, 2018 EX-10.1

Retention Agreement, dated July 20, 2018, by and between the Registrant and Jeffrey D. Abbey

EX-10.1 2 exh101.htm EXHIBIT 10.1 Exhibit 10.1 RETENTION AGREEMENT This Retention Agreement (the “Agreement”) is entered into as of July 20, 2018, by and between Argos Therapeutics, Inc. (the “Company”) and Jeffrey D. Abbey (“Executive”). WHEREAS, Executive and the Company entered into that certain offer letter dated December 9, 2013 (the “Offer Letter”); and WHEREAS, the Offer Letter provides for

November 19, 2018 EX-10.2

Retention Agreement, dated July 20, 2018, by and between the Registrant and Richard Katz

Exhibit 10.2 RETENTION AGREEMENT This Retention Agreement (the “Agreement”) is entered into as of July 20, 2018, by and between Argos Therapeutics, Inc. (the “Company”) and Richard D. Katz (“Executive”). WHEREAS, Executive and the Company entered into that certain offer letter dated July 1, 2016 (the “Offer Letter”); and WHEREAS, the Offer Letter provides for the payment of certain amounts of sala

November 19, 2018 EX-10.3

Retention Agreement, dated July 20, 2018, by and between the Registrant and Charles Nicolette

Exhibit 10.3 RETENTION AGREEMENT This Retention Agreement (the “Agreement”) is entered into as of July 20, 2018, by and between Argos Therapeutics, Inc. (the “Company”) and Charles Nicolette (“Executive”). WHEREAS, Executive and the Company entered into that certain offer letter dated December 9, 2013 (the “Offer Letter”); and WHEREAS, the Offer Letter provides for the payment of certain amounts o

November 14, 2018 NT 10-Q

ARGS / Argos Therapeutics, Inc. FORM NT 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING SEC FILE NUMBER 001-35443 CUSIP NUMBER 040221 202 (Check one): o Form 10-K o Form 20-F o Form 11-K x Form 10-Q o Form 10-D o Form N-SAR o Form N-CSR For Period Ended: September 30, 2018 o Transition Report on Form 10-K o Transition Report on Form 20-F o Transition Report on Form 11-K o T

August 20, 2018 10-Q

ARGS / Argos Therapeutics, Inc. FORM 10-Q (Quarterly Report)

10-Q 1 f10q082018p.htm FORM 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2018 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS THERAP

August 15, 2018 NT 10-Q

ARGS / Argos Therapeutics, Inc. FORM NT 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING SEC FILE NUMBER 001-35443 CUSIP NUMBER 040221 202 (Check one): o Form 10-K o Form 20-F o Form 11-K x Form 10-Q o Form 10-D o Form N-SAR o Form N-CSR For Period Ended: June 30, 2018 o Transition Report on Form 10-K o Transition Report on Form 20-F o Transition Report on Form 11-K o Transi

July 20, 2018 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

8-K 1 f8k072018.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): July 16, 2018 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction (Commis

May 15, 2018 S-8

ARGS / Argos Therapeutics, Inc. FORM S-8

As filed with the Securities and Exchange Commission on May 15, 2018 Registration No.

May 15, 2018 EX-10.4

Letter from the Registrant to Medinet Co., Ltd., dated February 14, 2018, regarding revocation of certain rights under the novated, amended and restated license agreement

Exhibit 10.4 February 14, 2018 BY EMAIL Medinet Co., Ltd. Shin-Yokohama Square Bldg. 14F, 2-3-12 Shin-Yokohama, Kohoku-ku, Yokohama, Kanagawa, 222-0033 JAPAN MEDcell Co., Ltd. 2-8 Tamagawa-dai Setagaya-ku Tokyo, 158-0096 JAPAN Re: Novated, Amended and Restated License Agreement Gentlemen: I am writing on behalf of Argos Therapeutics, Inc. (“Argos”) with respect to the Novated, Amended and Restated

May 15, 2018 10-Q

ARGS / Argos Therapeutics, Inc. FORM 10-Q (Quarterly Report)

10-Q 1 f10q051518p.htm FORM 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2018 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS THERA

May 15, 2018 EX-21.1

Subsidiaries of the Registrant

EX-21.1 3 exh211.htm EXHIBIT 21.1 Exhibit 21.1 Subsidiaries of the Registrant Name Jurisdiction DC Bio Corp. Nova Scotia, Canada Argos Therapeutics (Europe) S.à.r.l Bertrange, Luxembourg

April 24, 2018 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 19, 2018 Argos Therapeutics, Inc.

April 19, 2018 EX-99.1

Argos Therapeutics Reports Results of Interim Analysis of the ADAPT Trial and Announces Review of Strategic Alternatives - Company to terminate the ADAPT study – - Company has retained Stifel to provide advice on possible strategic alternatives – - T

EXHIBIT 99.1 Argos Therapeutics Reports Results of Interim Analysis of the ADAPT Trial and Announces Review of Strategic Alternatives - Company to terminate the ADAPT study – - Company has retained Stifel to provide advice on possible strategic alternatives – - Trading in the common stock to be transferred from Nasdaq to the OTCQB Venture Market - DURHAM, N.C., April 19, 2018 (GLOBE NEWSWIRE) - Ar

April 19, 2018 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event Reported): April 19, 2018 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporation) (Commission Fil

April 2, 2018 424B5

ARGOS THERAPEUTICS, INC. Up to $6,264,826 Common Stock

424B5 1 f424b5040218.htm 424B5 PROSPECTUS SUPPLEMENT (To Prospectus dated January 24, 2017) Filed Pursuant to Rule 424(b)(5) Registration No. 333-215480 ARGOS THERAPEUTICS, INC. Up to $6,264,826 Common Stock This prospectus supplement amends and supplements the information in the prospectus, dated January 24, 2017, filed as a part of our registration statement on Form S-3 (File No. 333-2215480), a

April 2, 2018 EX-10.49

Evaluation and Option Agreement for a Patent License, dated February 1, 2018, by and between the Registrant, Pharmstandard International S.A. and Actigen Limited (filed as Exhibit 10.49 to the Registrant’s Annual Report on Form 10-K on April 2, 2018 and incorporated herein by reference)

EX-10.49 3 exh1049.htm EXHIBIT 10.49 Exhibit 10.49 Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. Evaluation and Option Agreement for a Patent License This Evaluation and Option Agreement for a Patent License ("Agreement"), dated as of February 1, 2018 ("Effective Date"), is by and between Actigen Limited (“Patent

April 2, 2018 10-K

ARGS / Argos Therapeutics, Inc. FORM 10-K (Annual Report)

10-K 1 f10k040218p.htm FORM 10-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2017 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS THERAPEUTI

April 2, 2018 EX-10.51

Third Amendment to License Agreement, dated March 23, 2018, between the Registrant and Lummy (Hong Kong) Co., Ltd. (filed as Exhibit 10.51 to the Registrant’s Annual Report on Form 10-K on April 2, 2018 and incorporated herein by reference)

Exhibit 10.51 Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. Third Amendment to License Agreement between Argos Therapeutics, Inc. (hereinafter “Argos”) - and - Lummy (Hong Kong) Co., Ltd. (hereinafter “China Company”) This Amendment is made as of and effective March 23th, 2018 (“Effective Date”), contingent on th

April 2, 2018 EX-3.1

Restated Certificate of Incorporation of the Registrant, as amended

Exhibit 3.1 RESTATED CERTIFICATE OF INCORPORATION OF ARGOS THERAPEUTICS, INC. (originally incorporated on May 8, 1997 under the name Dendritix, Inc.) FIRST: The name of the Corporation is Argos Therapeutics, Inc. SECOND: The address of the Corporation’s registered office in the State of Delaware is 2711 Centerville Road, Suite 400, in the City of Wilmington, County of New Castle, 19808. The name o

April 2, 2018 EX-10.50

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions.

Exhibit 10.50 Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. Second Amendment to License Agreement between Argos Therapeutics, Inc. (hereinafter “Argos”) - and - Lummy (Hong Kong) Co., Ltd. (hereinafter “China Company”) This Amendment is made as of and effective 2017-10-18 (“Effective Date”), contingent on the ful

April 2, 2018 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

8-K 1 f8k040218.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event Reported): April 2, 2018 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of In

April 2, 2018 EX-99.1

Argos Therapeutics Reports Fourth Quarter and Full Year 2017 Financial Results and Operational Highlights

EXHIBIT 99.1 Argos Therapeutics Reports Fourth Quarter and Full Year 2017 Financial Results and Operational Highlights DURHAM, NC, April 02, 2018 (GLOBE NEWSWIRE) - Argos Therapeutics, Inc. (Nasdaq:ARGS), an immuno-oncology company focused on the development and commercialization of individualized immunotherapies based on the Arcelis® precision immunotherapy technology platform, today reported fin

March 7, 2018 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event Reported): March 7, 2018 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporation) (Commission File

February 16, 2018 8-K

Other Events

8-K 1 f8k021618.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event Reported): February 15, 2018 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction o

February 14, 2018 EX-99.1

Joint Filing Agreement

EX-99.1 Exhibit 99.1 Joint Filing Agreement In accordance with Rule 13d-1(f) under the Securities and Exchange Act of 1934, the persons or entities named below agree to the joint filing on behalf of each of them of a statement on Schedule 13D (including amendments thereto) with respect to the Shares of the Issuer and further agree that this joint filing agreement be included as an exhibit to this

February 14, 2018 SC 13D/A

ARGS / Argos Therapeutics, Inc. / ForArgos B.V. - SC 13D/A Activist Investment

SC 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13D UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 1 )* ARGOS THERAPEUTICS INC. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 040221 103 (CUSIP Number) ForArgos B.V. Gooimeer 2-35, 1411 DC Naarden The Netherlands (Name, Address and Telephone Number of Perso

February 14, 2018 EX-99.2

Shareholders’ Agreement January 27, 2016 ForArgos B.V. by and among Coöperatieve AAC LS U.A. Forbion Co-Investment II Coöperatief U.A. Forbion CF II Co-Invest I Coöperatief U.A.

EX-99.2 3 d719744dex992.htm EX-99.2 Exhibit 99.2 Shareholders’ Agreement January 27, 2016 ForArgos B.V. by and among Coöperatieve AAC LS U.A. and Forbion Co-Investment II Coöperatief U.A. and Forbion CF II Co-Invest I Coöperatief U.A. FORARGOS B.V. (“ForArgos”) is a private company with limited liability incorporated under the laws of the Netherlands (besloten vennootschap met beperkte aansprakeli

February 5, 2018 EX-99.1

Argos Obtains Option to License PD1 Checkpoint Inhibitors - Data showing synergy between PD1 checkpoint inhibition and analogue of Rocapuldencel-T in a preclinical model of renal carcinoma presented at ASCO-SITC - - Company to host a conference call

EdgarFiling EXHIBIT 99.1 Argos Obtains Option to License PD1 Checkpoint Inhibitors - Data showing synergy between PD1 checkpoint inhibition and analogue of Rocapuldencel-T in a preclinical model of renal carcinoma presented at ASCO-SITC - - Company to host a conference call on Tuesday, February 6, 2018 at 8:30 a.m. ET - DURHAM, N.C., Feb. 05, 2018 (GLOBE NEWSWIRE) - Argos Therapeutics Inc. (NASDAQ

February 5, 2018 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event Reported): February 1, 2018 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporation) (Commission F

February 5, 2018 EX-1.1

Amended and Restated Sales Agreement, dated as of February 2, 2018, by and between the Company and Cowen and Company, LLC

Exhibit 1.1 ARGOS THERAPEUTICS, INC. Common Stock (par value $0.001 per share) AMENDED AND RESTATED SALES AGREEMENT February 2, 2018 Cowen and Company, LLC 599 Lexington Avenue New York, NY 10022 Ladies and Gentlemen: Reference is made to that certain Sales Agreement, dated May 8, 2015 (the ?Sales Agreement?), by and between Argos Therapeutics, Inc. (the ?Company?) and Cowen and Company, LLC (?Cow

February 2, 2018 424B5

ARGOS THERAPEUTICS, INC. Common Stock

As Filed Pursuant to Rule 424(b)(5) Registration No. 333-215480 PROSPECTUS SUPPLEMENT (To Prospectus Dated January 24, 2017) ARGOS THERAPEUTICS, INC. $15,000,000 Common Stock On May 8, 2015, we entered into a sales agreement, or the original sales agreement, with Cowen and Company, LLC, or Cowen, pursuant to which we could, from time to time, offer and sell shares of our common stock, $0.001 par v

January 30, 2018 EX-3.1

Certificate of Amendment to Restated Certificate of Incorporation of Argos Therapeutics, Inc. (filed with the Secretary of State of the State of Delaware on January 18, 2018)

Exhibit 3.1 CERTIFICATE OF AMENDMENT OF RESTATED CERTIFICATE OF INCORPORATION OF ARGOS THERAPEUTICS, INC. ARGOS Therapeutics, Inc. (the ?Corporation?), a corporation organized and existing under and by virtue of the provisions of the General Corporation Law of the State of Delaware (the ?General Corporation Law?), does hereby certify as follows: 1. The current name of the Corporation is Argos Ther

January 30, 2018 8-K/A

Financial Statements and Exhibits

8-K/A 1 f8ka013018.htm FORM 8-K/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K/A (Amendment No. 1) CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event Reported): January 18, 2018 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State

January 22, 2018 CORRESP

ARGS / Argos Therapeutics, Inc. ESP

CORRESP 1 filename1.htm January 22, 2018 Via EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: Argos Therapeutics, Inc. Registration Statement on Form S-3 File No. 333-222414 Request for Acceleration Ladies and Gentlemen: Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended, Argos Therapeutics, Inc. (the

January 18, 2018 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Material Modification to Rights of Security Holders, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event Reported): January 17, 2018 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporation) (Commission F

January 8, 2018 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event Reported): January 8, 2018 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporation) (Commission Fi

January 8, 2018 EX-99.1

Argos Announces $1.5 Million Equity Investment by Lummy (Hong Kong), Ltd.

EdgarFiling EXHIBIT 99.1 Argos Announces $1.5 Million Equity Investment by Lummy (Hong Kong), Ltd. DURHAM, N.C., Jan. 08, 2018 (GLOBE NEWSWIRE) - Argos Therapeutics Inc. (NASDAQ:ARGS), an immuno-oncology company focused on the development and commercialization of individualized immunotherapies based on the Arcelis? precision immunotherapy technology platform, today announced that it has signed a s

January 4, 2018 S-3

ARGS / Argos Therapeutics, Inc. FORM S-3

S-3 1 fs3010418.htm FORM S-3 As filed with the Securities and Exchange Commission on January 4, 2018 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM S-3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 ARGOS THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 56-2110007 (State or other jurisdiction of incorpor

November 28, 2017 EX-10.1

Satisfaction and Release Agreement, dated November 22, 2017, by and between the Company and Saint-Gobain Performance Plastics Corporation, including a form of the Convertible Unsecured Promissory Note to be issued by the Company

Exhibit 10.1 SATISFACTION AND RELEASE AGREEMENT This SATISFACTION AND RELEASE AGREEMENT (the ?Agreement?) is dated as of the 22nd day of November, 2017, by and between ARGOS THERAPEUTICS, INC., a Delaware corporation (?Argos?) and SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION, a California corporation (?SGPPL?). Reference is made to that certain Development Agreement dated as of January 5, 2015, b

November 28, 2017 EX-99.1

Argos Provides Financial Update

EdgarFiling EXHIBIT 99.1 Argos Provides Financial Update DURHAM, N.C., Nov. 28, 2017 (GLOBE NEWSWIRE) - Argos Therapeutics Inc. (NASDAQ:ARGS), an immuno-oncology company focused on the development and commercialization of individualized immunotherapies based on the Arcelis? precision immunotherapy technology platform, today announced that TKC Properties, the landlord of the facility in Durham Coun

November 28, 2017 EX-10.2

Registration Rights Agreement, dated November 22, 2017, by and between the Company and Saint-Gobain Performance Plastics Corporation

Exhibit 10.2 REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (this ?Agreement?) is made and entered into as of November 22, 2017 by and among Argos Therapeutics, Inc., a Delaware corporation (the ?Company?), and Saint-Gobain Plastics Performance Corporation, a California corporation (?Saint-Gobain?). The parties hereby agree as follows: 1. Certain Definitions. As used in this Agre

November 28, 2017 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Other Events

8-K 1 f8k112817.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 22, 2017 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of

November 17, 2017 CORRESP

ARGS / Argos Therapeutics, Inc. ESP

November 17, 2017 Via EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.

November 9, 2017 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing

8-K 1 f8k110917.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 8, 2017 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of I

November 9, 2017 EX-10.4

Form of Restricted Stock Agreement under the 2014 Stock Incentive Plan

Exhibit 10.4

November 9, 2017 10-Q

ARGS / Argos Therapeutics, Inc. FORM 10-Q (Quarterly Report)

10-Q 1 f10q110917p.htm FORM 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2017 or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS T

November 6, 2017 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 1, 2017 Argos Therapeutics, Inc.

November 3, 2017 S-3

Argos Therapeutics FORM S-3

As filed with the Securities and Exchange Commission on November 3, 2017 Registration No.

October 27, 2017 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): October 26, 2017 Argos Therapeutics, Inc.

September 28, 2017 EX-24.1

Limited Power Of Attorney For Section 16 Reporting Obligations

Exhibit 24.1 Limited Power Of Attorney For Section 16 Reporting Obligations Know all by these presents, that the undersigned hereby makes, constitutes and appoints each of Jeffrey D. Abbey, Richard D. Katz and Lori R. Harrelson, signing singly and each acting individually, as the undersigned?s true and lawful attorney-in-fact with full power and authority as hereinafter described to: (1) execute f

September 26, 2017 EX-99.1

Argos Therapeutics Announces Appointment of Richard Morrison, PhD to Board of Directors

EX-99.1 2 exh991.htm PRESS RELEASE EXHIBIT 99.1 Argos Therapeutics Announces Appointment of Richard Morrison, PhD to Board of Directors DURHAM, N.C., Sept. 26, 2017 (GLOBE NEWSWIRE) - Argos Therapeutics Inc. (NASDAQ:ARGS), an immuno-oncology company focused on the development and commercialization of individualized immunotherapies based on the Arcelis® precision immunotherapy technology platform,

September 26, 2017 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event Reported): September 26, 2017 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporation) (Commission

September 25, 2017 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 22, 2017 Argos Therapeutics, Inc.

September 25, 2017 EX-10.1

Satisfaction and Release Agreement, dated September 22, 2017, by and between the Company and Invetech Pty Ltd, including a form of Convertible Unsecured Promissory Note to be issued by the Company (filed as Exhibit 10.1 to the Registrant’s Current Report on Form 8-K filed on September 25, 2017 and incorporated herein by reference)

Exhibit 10.1 SATISFACTION AND RELEASE AGREEMENT This SATISFACTION AND RELEASE AGREEMENT (the ?Agreement?) is dated as of the 22nd day of September, 2017, by and between ARGOS THERAPEUTICS, INC., a Delaware corporation (?Argos?) and INVETECH PTY LTD, an Australian company (?Invetech?). Reference is made to that certain Development Agreement with an effective date of October 7, 2013, by and between

September 25, 2017 EX-10.2

Registration Rights Agreement, dated September 22, 2017, by and between the Company and Invetech Pty Ltd

Exhibit 10.2 REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (this ?Agreement?) is made and entered into as of September 22, 2017 by and among Argos Therapeutics, Inc., a Delaware corporation (the ?Company?), and Invetech Pty Ltd (?Invetech?). The parties hereby agree as follows: 1. Certain Definitions. As used in this Agreement, the following terms shall have the following meanin

September 12, 2017 8-K

Financial Statements and Exhibits, Other Events

8-K 1 f8k091217.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event Reported): September 12, 2017 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction

September 12, 2017 EX-99.1

Argos Therapeutics Reports on Interim Analysis of Phase 3 ADAPT Trial Presented at ESMO 2017 Congress

EX-99.1 2 exh991.htm EXHIBIT 99.1 EXHIBIT 99.1 Argos Therapeutics Reports on Interim Analysis of Phase 3 ADAPT Trial Presented at ESMO 2017 Congress DURHAM, N.C., Sept. 12, 2017 (GLOBE NEWSWIRE) - Argos Therapeutics Inc. (NASDAQ:ARGS), an immuno-oncology company focused on the development and commercialization of individualized immunotherapies based on the Arcelis® precision immunotherapy technolo

September 5, 2017 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

8-K 1 f8k090517.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event Reported): August 30, 2017 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of

August 30, 2017 S-8

Argos Therapeutics FORM S-8

As filed with the Securities and Exchange Commission on August 30, 2017 Registration No.

August 24, 2017 CORRESP

ARGS / Argos Therapeutics, Inc. ESP

CORRESP 1 filename1.htm August 24, 2017 Via EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: Argos Therapeutics, Inc. Registration Statement on Form S-3 File No. 333-220001 Request for Acceleration Ladies and Gentlemen: Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended, Argos Therapeutics, Inc. (the “

August 16, 2017 S-3

Argos Therapeutics FORM S-3

As filed with the Securities and Exchange Commission on August 16, 2017 Registration No.

August 9, 2017 10-Q

ARGS / Argos Therapeutics, Inc. FORM 10-Q (Quarterly Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2017 or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS THERAPEUTICS, INC. (Exact name of regis

August 2, 2017 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 28, 2017 ARGOS THERAPEUTICS, INC. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporation) (Commission File

August 2, 2017 EX-10.1

2014 Stock Incentive Plan, as amended

Exhibit 10.1 ARGOS THERAPEUTICS, INC. 2014 STOCK INCENTIVE PLAN 1. Purpose The purpose of this 2014 Stock Incentive Plan (the ?Plan?) of Argos Therapeutics, Inc., a Delaware corporation (the ?Company?), is to advance the interests of the Company?s stockholders by enhancing the Company?s ability to attract, retain and motivate persons who are expected to make important contributions to the Company

July 6, 2017 DEF 14A

Argos Therapeutics FORM DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of

June 26, 2017 SC 13D/A

ARGS / Argos Therapeutics, Inc. / Pharmstandard International S.A. - SCHEDULE 13DA BY PHARMSTANDARD INTERNATIONAL S.A. FOR ARGOS THERAPEUTICS, INC. Activist Investment

SC 13D/A 1 s13da062217-argostherap.htm SCHEDULE 13DA BY PHARMSTANDARD INTERNATIONAL S.A. FOR ARGOS THERAPEUTICS, INC. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 5)* ARGOS THERAPEUTICS, INC. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 040221 103 (CUSIP Numb

June 23, 2017 PRE 14A

Argos Therapeutics PRE 14A

PRE 14A 1 pre14a062317.htm PRE 14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: x Preliminary Proxy S

June 16, 2017 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Other Events

8-K 1 f8k061617.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 15, 2017 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Inco

June 16, 2017 EX-10.1

NOTE PURCHASE AGREEMENT

Exhibit 10.1 NOTE PURCHASE AGREEMENT This NOTE PURCHASE AGREEMENT (this ?Agreement?) is made and entered into as of June 15, 2017 by and among Argos Therapeutics, Inc., a Delaware corporation (the ?Company?) and Pharmstandard International S.A. (the ?Investor?). Recitals A. The Investor wishes to purchase from the Company, and the Company wishes to sell and issue to the Investor, upon the terms an

June 16, 2017 EX-10.2

REGISTRATION RIGHTS AGREEMENT

Exhibit 10.2 REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (this ?Agreement?) is made and entered into as of June 15, 2017 by and among Argos Therapeutics, Inc., a Delaware corporation (the ?Company?), and Pharmstandard International S.A. (?PHS?). Capitalized terms used herein have the respective meanings ascribed thereto in that certain Note Purchase Agreement dated as of the d

June 16, 2017 EX-99.1

Argos Therapeutics Announces $6,000,000 Secured Convertible Note Financing

EdgarFiling EXHIBIT 99.1 Argos Therapeutics Announces $6,000,000 Secured Convertible Note Financing DURHAM, N.C., June 16, 2017 (GLOBE NEWSWIRE) - Argos Therapeutics, Inc. (Nasdaq:ARGS), an immuno-oncology company focused on the development and commercialization of individualized immunotherapies for the treatment of cancer and infectious diseases based on the Arcelis? technology platform, today an

May 10, 2017 EX-10.7

Lease Termination Agreement, dated March 31, 2017, by and between Registrant and Keystone-Centennial II, LLC

Exhibit 10.7 LEASE TERMINATION AGREEMENT THIS LEASE TERMINATION AGREEMENT (this "Agreement") is entered into effective March 31, 2017, by and between Keystone-Centennial II, LLC, a North Carolina limited liability company, ("Landlord"), and Argos Therapeutics, Inc., a Delaware corporation, ("Tenant"). RECITALS Pursuant to that Lease Agreement dated January 17, 2017, entered into by Tenant and Land

May 10, 2017 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2017 or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS THERAPEUTICS, INC. (Exact name of regi

May 10, 2017 EX-10.6

First Amendment to License Agreement, dated December 5, 2016, by and between Registrant and Lummy (Hong Kong) Co., Ltd.

Confidential Materials omitted and filed separately with the Securities and Exchange Commission.

May 4, 2017 8-K

Argos Therapeutics FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 28, 2017 Argos Therapeutics, Inc.

May 1, 2017 10-K/A

Argos Therapeutics FORM 10-K/A (Annual Report)

10-K/A 1 f10ka050117.htm FORM 10-K/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 Form 10-K/A (Amendment No. 1) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2016 o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commiss

April 18, 2017 8-K

Argos Therapeutics FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 18, 2017 Argos Therapeutics, Inc.

April 18, 2017 EX-99.1

Argos Reports Interim Results of the ADAPT Trial and Provides Perspective on Decision to Continue the Trial

EdgarFiling EXHIBIT 99.1 Argos Reports Interim Results of the ADAPT Trial and Provides Perspective on Decision to Continue the Trial DURHAM, N.C., April 18, 2017 (GLOBE NEWSWIRE) - Argos Therapeutics Inc. (Nasdaq:ARGS), an immuno-oncology company focused on the development and commercialization of individualized immunotherapies based on the Arcelis? precision immunotherapy technology platform, tod

April 18, 2017 EX-99.2

Webcast April 18, 2017 Results of February Interim Analysis of ADAPT Trial and Perspective on Decision to Keep Trial Open Any statements in this presentation about Argos' future expectations, plans and prospects, including statements about the ADAPT

EXHIBIT 99.2 Webcast April 18, 2017 Results of February Interim Analysis of ADAPT Trial and Perspective on Decision to Keep Trial Open Any statements in this presentation about Argos' future expectations, plans and prospects, including statements about the ADAPT trial and the interim data from the trial, Argos' anticipated meeting with the FDA, clinical development of Argos' product candidates and

April 13, 2017 8-K

Argos Therapeutics FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 13, 2017 Argos Therapeutics, Inc.

April 4, 2017 8-K

Argos Therapeutics FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 31, 2017 Argos Therapeutics, Inc.

March 28, 2017 S-8

Argos Therapeutics FORM S-8

S-8 1 s8032717.htm FORM S-8 As filed with the Securities and Exchange Commission on March 28, 2017 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 ARGOS THERAPEUTICS, INC. (Exact Name of Registrant as Specified in Its Charter) Delaware 56-2110007 (State or Other Jurisdiction of Incorporat

March 23, 2017 8-K

Argos Therapeutics FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 17, 2017 Argos Therapeutics, Inc.

March 16, 2017 EX-4.3

EX-4.3

Exhibit 4.3

March 16, 2017 EX-10.44

Confidential Materials omitted and filed separately with the Securities and Exchange Commission .Double asterisks denote omissions.

Exhibit 10.44 Confidential Materials omitted and filed separately with the Securities and Exchange Commission .Double asterisks denote omissions. OMB Approval 2700-0042 1. CONTRACT ID CODE PAGE OF PAGES AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT 1 6 2. AMENDMENT/MODIFICATION NO. 3. EFFECTIVE DATE 4. REQUISITION/PURCHASE REQ. NO. 5. PROJECT NO. (If applicable) Thirteen (13) See Block 16C. N

March 16, 2017 EX-10.40

LEASE TERM SHEET

Exhibit 10.40 LEASE TERM SHEET THIS LEASE TERM SHEET is made a part of the attached Lease Agreement between Landlord and Tenant. Use of the following capitalized terms (indicated in bold type) in this Lease shall be deemed a reference to the information set out below. • Landlord: Keystone-Centennial II, LLC a North Carolina limited liability company 5410 Trinity Road, Suite 215 Raleigh, NC 27607 A

March 16, 2017 EX-10.28

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. SECOND AMENDMENT

Exhibit 10.28 Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. SECOND AMENDMENT THIS SECOND AMENDMENT TO DEVELOPMENT AGREEMENT (the ?Second Amendment?) is entered into by and between SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION, a California corporation having an office at 31500 Solon Road, Solon, OH 44139 (?SGPPL?

March 16, 2017 EX-4.5

AMENDMENT NO. 3 TO FIFTH AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT

Exhibit 4.5 AMENDMENT NO. 3 TO FIFTH AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT This Amendment No. 3 (this ?Amendment?) to the Fifth Amended and Restated Registration Rights Agreement, dated August 9, 2013 (the ?Registration Rights Agreement?), by and among the Company and the Holders (as defined therein) is entered into as of the 6th day of March, 2017 by and among Argos Therapeutics, Inc

March 16, 2017 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2016 or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS THERAPEUTICS, INC. (Exact name of registran

March 9, 2017 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Costs Associated with Exit or Disposal Activities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 8, 2017 Argos Therapeutics, Inc.

March 6, 2017 EX-10.1

March 2, 2017

EX-10.1 2 exh101.htm EXHIBIT 10.1 Exhibit 10.1 March 2, 2017 VIA ELECTRONIC AND REGULAR MAIL Argos Therapeutics, Inc. 4233 Technology Drive Durham, NC 27704 Attn: Vice President of Finance Re: Venture Loan and Security Agreement dated as of September 29, 2014 (as amended from time to time, the “Loan Agreement”) by and among Argos Therapeutics, Inc. (“Borrower”), Horizon Credit II LLC (“HCII”), as

March 6, 2017 EX-10.2

ARGOS THERAPEUTICS, INC. WARRANT TO PURCHASE SHARES OF COMMON STOCK

Exhibit 10.2 THIS WARRANT AND THE SHARES ISSUABLE UPON EXERCISE OF THIS WARRANT HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED OR ANY STATE SECURITIES LAWS. NO SALE OR DISPOSITION MAY BE EFFECTED WITHOUT (i) EFFECTIVE REGISTRATION STATEMENTS RELATED THERETO, (ii) AN OPINION OF COUNSEL OR OTHER EVIDENCE, REASONABLY SATISFACTORY TO THE COMPANY, THAT SUCH REGISTRATIONS ARE NOT

March 6, 2017 8-K

Termination of a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 3, 2017 Argos Therapeutics, Inc.

March 6, 2017 EX-10.3

ARGOS THERAPEUTICS, INC. WARRANT TO PURCHASE SHARES OF COMMON STOCK

Exhibit 10.3 THIS WARRANT AND THE SHARES ISSUABLE UPON EXERCISE OF THIS WARRANT HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED OR ANY STATE SECURITIES LAWS. NO SALE OR DISPOSITION MAY BE EFFECTED WITHOUT (i) EFFECTIVE REGISTRATION STATEMENTS RELATED THERETO, (ii) AN OPINION OF COUNSEL OR OTHER EVIDENCE, REASONABLY SATISFACTORY TO THE COMPANY, THAT SUCH REGISTRATIONS ARE NOT

March 6, 2017 EX-10.4

ARGOS THERAPEUTICS, INC. WARRANT TO PURCHASE SHARES OF COMMON STOCK

Exhibit 10.4 THIS WARRANT AND THE SHARES ISSUABLE UPON EXERCISE OF THIS WARRANT HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED OR ANY STATE SECURITIES LAWS. NO SALE OR DISPOSITION MAY BE EFFECTED WITHOUT (i) EFFECTIVE REGISTRATION STATEMENTS RELATED THERETO, (ii) AN OPINION OF COUNSEL OR OTHER EVIDENCE, REASONABLY SATISFACTORY TO THE COMPANY, THAT SUCH REGISTRATIONS ARE NOT

March 2, 2017 EX-99.2

Shareholders’ Agreement January 27, 2016 ForArgos B.V. by and among Coöperatieve AAC LS U.A. Forbion Co-Investment II Coöperatief U.A. Forbion CF II Co-Invest I Coöperatief U.A.

EX-99.2 Exhibit 99.2 Shareholders’ Agreement January 27, 2016 ForArgos B.V. by and among Coöperatieve AAC LS U.A. and Forbion Co-Investment II Coöperatief U.A. and Forbion CF II Co-Invest I Coöperatief U.A. FORARGOS B.V. (“ForArgos”) is a private company with limited liability incorporated under the laws of the Netherlands (besloten vennootschap met beperkte aansprakelijkheid) on January 27, 2016.

March 2, 2017 EX-99.1

Joint Filing Agreement

EX-99.1 CUSIP No. 040221 103 Exhibit 99.1 Joint Filing Agreement In accordance with Rule 13d-1(f) under the Securities and Exchange Act of 1934, the persons or entities named below agree to the joint filing on behalf of each of them of a statement on Schedule 13D (including amendments thereto) with respect to the Shares of the Issuer and further agree that this joint filing agreement be included a

March 2, 2017 SC 13D

ARGS / Argos Therapeutics, Inc. / ForArgos B.V. - SC 13D Activist Investment

SC 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13D UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. )* ARGOS THERAPEUTICS INC. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 040221 103 (CUSIP Number) ForArgos B.V. Gooimeer 2-35, 1411 DC Naarden The Netherlands (Name, Address and Telephone Number of Person Au

February 22, 2017 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 22, 2017 Argos Therapeutics, Inc.

February 13, 2017 SC 13G/A

ARGS / Argos Therapeutics, Inc. / INTERSOUTH PARTNERS IV LP /NC - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G (Amendment No. 1) Under the Securities Exchange Act of 1934 Argos Therapeutics, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 040221103 (CUSIP Number) December 31, 2016 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this

January 23, 2017 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event Reported): January 17, 2017 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporation) (Commission F

January 23, 2017 EX-99.1

Argos Therapeutics Completes Lease Agreement for Commercial Manufacturing Space on the Centennial Campus of North Carolina State University 40,000 square feet of newly constructed space at the Center for Technology & Innovation to support initial com

EdgarFiling

January 20, 2017 CORRESP

Argos Therapeutics ESP

January 20, 2017 Via EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.

January 9, 2017 EX-4.6

Form of Subordinated Note (FACE OF SECURITY)

Exhibit 4.6 Form of Subordinated Note (FACE OF SECURITY) [Each Global Security shall bear substantially the following legend: UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE REGISTERED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE

January 9, 2017 S-3

As filed with the Securities and Exchange Commission on January 9, 2017

As filed with the Securities and Exchange Commission on January 9, 2017 Registration No.

January 9, 2017 EX-4.5

Form of Senior Note (FACE OF SECURITY)

Exhibit 4.5 Form of Senior Note (FACE OF SECURITY) [Each Global Security shall bear substantially the following legend: UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE REGISTERED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE OF THE

January 9, 2017 EX-12.1

RATIOS OF EARNINGS TO FIXED CHARGES AND RATIOS OF EARNINGS TO COMBINED FIXED CHARGES AND PREFERRED STOCK DIVIDENDS

Exhibit 12.1 RATIOS OF EARNINGS TO FIXED CHARGES AND RATIOS OF EARNINGS TO COMBINED FIXED CHARGES AND PREFERRED STOCK DIVIDENDS The following table sets forth our ratio of earnings to fixed charges and ratios of earnings to combined fixed charges and preferred stock dividends for each of the periods indicated. Fixed charges include interest expense on debt, amortization of discount and the portion

January 9, 2017 EX-4.4

ARGOS THERAPEUTICS, INC. Dated as of _______________ SUBORDINATED DEBT SECURITIES CROSS-REFERENCE TABLE(1)

EX-4.4 3 exh44.htm EXHIBIT 4.4 Exhibit 4.4 ARGOS THERAPEUTICS, INC. and Trustee INDENTURE Dated as of SUBORDINATED DEBT SECURITIES CROSS-REFERENCE TABLE(1) Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 6.09 310(b) 6.08 6.10 310(c) Inapplicable 311(a) 6.13 311(b) 6.13 311(c) Inapplicable 312(a) 4.01 4.04 312(b) 4.04(c) 312(c) 4.04(c) 313(a) 4.03 313(b) 4.03 313(c) 4

January 9, 2017 EX-4.3

ARGOS THERAPEUTICS, INC. Dated as of _______________ SENIOR DEBT SECURITIES

Exhibit 4.3 ARGOS THERAPEUTICS, INC. and Trustee INDENTURE Dated as of SENIOR DEBT SECURITIES i CROSS-REFERENCE TABLE(1) Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 6.09 310(b) 6.08 6.10 310(c) Inapplicable 311(a) 6.13 311(b) 6.13 311(c) Inapplicable 312(a) 4.01 4.04 312(b) 4.04(c) 312(c) 4.04(c) 313(a) 4.03 313(b) 4.03 313(c) 4.03 313(d) 4.03 314(a) 4.02 314(b)

December 15, 2016 EX-99.1

Argos Therapeutics Appoints Dr. Ralph Snyderman and Irackly Mtibelishvily to the Company’s Board of Directors - Dr. Snyderman widely considered the ‘Father of Personalized Medicine’ -

EdgarFiling

December 15, 2016 8-K

Argos Therapeutics FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event Reported): December 9, 2016 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporation) (Commission F

November 14, 2016 8-K

Argos Therapeutics FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event Reported): November 14, 2016 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporation) (Commission

November 14, 2016 EX-99.1

Argos Therapeutics Reports Third Quarter 2016 Financial Results and Recent Operational Highlights - Dr. Richard D. Katz Joined as Chief Financial Officer - - Raised Gross Proceeds of $50 million in Follow-on Offering - - First Patient Dosed in Stage

EX-99.1 2 exh991.htm PRESS RELEASE EXHIBIT 99.1 Argos Therapeutics Reports Third Quarter 2016 Financial Results and Recent Operational Highlights - Dr. Richard D. Katz Joined as Chief Financial Officer - - Raised Gross Proceeds of $50 million in Follow-on Offering - - First Patient Dosed in Stage 2 of Adult Eradication Trial of AGS-004 in HIV - - Investor Day Scheduled for December 7, 2016 - - Thi

November 14, 2016 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q _________________

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2016 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS THERAPEUTICS, INC. (Exact name of

November 14, 2016 EX-10.4

SIXTH AMENDMENT TO LEASE AGREEMENT AND FIFTH AMENDMENT TO PURCHASE AND SALE AGREEMENT

Exhibit 10.4 SIXTH AMENDMENT TO LEASE AGREEMENT AND FIFTH AMENDMENT TO PURCHASE AND SALE AGREEMENT THIS SIXTH AMENDMENT TO LEASE AGREEMENT AND FIFTH AMENDMENT TO PURCHASE AND SALE AGREEMENT (this ?Agreement?), is dated effective as of September 30, 2016 (the ?Effective Date?), by and between TKC LXXII, LLC, a North Carolina limited liability company (?TKC?), and ARGOS THERAPEUTICS, INC., a Delawar

October 18, 2016 SC 13D/A

Argos Therapeutics SCHEDULE 13D/A - AMENDMENT NO. 4 FOR ARGOS THERAPEUTICS, INC. BY PHARMSTANDARD INTERNATIONAL S.A. (Activist Acquisition of More Than 5% of Shares)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 4)* ARGOS THERAPEUTICS, INC. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 040221 103 (CUSIP Number) Pharmstandard International S.A 10a, rue Henri Schnadt Luxembourg, N4 L-2530 +352 24840131 (Name, Address and Tele

August 18, 2016 SC 13D/A

ARGS / Argos Therapeutics, Inc. / Pharmstandard International S.A. - SCHEDULE 13D/A FOR ARGOS THERAPEUTICS, INC. BY PHARMSTANDARD INTERNATIONAL S.A. Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 3)* ARGOS THERAPEUTICS, INC. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 040221 103 (CUSIP Number) Pharmstandard International S.A 10a, rue Henri Schnadt Luxembourg, N4 L-2530 +352 24840131 (Name, Address and Tele

August 18, 2016 SC 13D/A

ARGS / Argos Therapeutics, Inc. / Pharmstandard International S.A. - SCHEDULE 13D/A FOR ARGOS THERAPEUTICS, INC. BY PHARMSTANDARD INTERNATIONAL S.A. Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 3)* ARGOS THERAPEUTICS, INC. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 040221 103 (CUSIP Number) Pharmstandard International S.A 10a, rue Henri Schnadt Luxembourg, N4 L-2530 +352 24840131 (Name, Address and Tele

August 15, 2016 S-8

Argos Therapeutics FORM S-8

S-8 1 fs8081516.htm FORM S-8 As filed with the Securities and Exchange Commission on August 15, 2016 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 56-2110007 (State or Other Jurisdiction of Incorpor

August 15, 2016 EX-99.1

ARGOS THERAPEUTICS, INC. Nonstatutory Stock Option Agreement

Exhibit 99.1 ARGOS THERAPEUTICS, INC. Nonstatutory Stock Option Agreement 1. Grant of Option. This agreement evidences the grant by Argos Therapeutics, Inc., a Delaware corporation (the ?Company?), on July 11, 2016 (the ?Grant Date?) to Richard Katz, an employee of the Company (the ?Participant?), of an option to purchase, in whole or in part, on the terms provided herein, a total of 300,000 share

August 15, 2016 EX-99.1

ARGOS THERAPEUTICS, INC. Nonstatutory Stock Option Agreement

Exhibit 99.1 ARGOS THERAPEUTICS, INC. Nonstatutory Stock Option Agreement 1. Grant of Option. This agreement evidences the grant by Argos Therapeutics, Inc., a Delaware corporation (the ?Company?), on July 11, 2016 (the ?Grant Date?) to Richard Katz, an employee of the Company (the ?Participant?), of an option to purchase, in whole or in part, on the terms provided herein, a total of 300,000 share

August 15, 2016 S-8

Argos Therapeutics FORM S-8

S-8 1 fs8081516.htm FORM S-8 As filed with the Securities and Exchange Commission on August 15, 2016 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 56-2110007 (State or Other Jurisdiction of Incorpor

August 15, 2016 EX-10.1

ARGOS THERAPEUTICS, INC. 4233 TECHNOLOGY DRIVE DURHAM, NC 27704

Exhibit 10.1 ARGOS THERAPEUTICS, INC. 4233 TECHNOLOGY DRIVE DURHAM, NC 27704 June 10, 2016 VIA email Joan C. Winterbottom 6986 Phillips Mill Road New Hope, PA 18938 Re: Amended and Restated Offer Letter Dear Joan: This letter agreement (the “Agreement”) shall serve to amend and restate the terms and conditions of the employment offer letter dated February 3, 2015 (the “Offer Letter”) between you a

August 15, 2016 EX-10.3

FIFTH AMENDMENT TO LEASE AGREEMENT AND THIRD AMENDMENT TO PURCHASE AND SALE AGREEMENT

Exhibit 10.3 EXECUTION COPY FIFTH AMENDMENT TO LEASE AGREEMENT AND THIRD AMENDMENT TO PURCHASE AND SALE AGREEMENT THIS FIFTH AMENDMENT TO LEASE AGREEMENT AND THIRD AMENDMENT TO PURCHASE AND SALE AGREEMENT (this “Omnibus Amendment”), dated effective as of July 1, 2016, by and between TKC LXXII, LLC, a North Carolina limited liability company (“TKC”), and ARGOS THERAPEUTICS, INC., a Delaware corpora

August 15, 2016 EX-10.1

ARGOS THERAPEUTICS, INC. 4233 TECHNOLOGY DRIVE DURHAM, NC 27704

Exhibit 10.1 ARGOS THERAPEUTICS, INC. 4233 TECHNOLOGY DRIVE DURHAM, NC 27704 June 10, 2016 VIA email Joan C. Winterbottom 6986 Phillips Mill Road New Hope, PA 18938 Re: Amended and Restated Offer Letter Dear Joan: This letter agreement (the “Agreement”) shall serve to amend and restate the terms and conditions of the employment offer letter dated February 3, 2015 (the “Offer Letter”) between you a

August 15, 2016 EX-4.2

AMENDMENT NO. 2 TO FIFTH AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT

Exhibit 4.2 AMENDMENT NO. 2 TO FIFTH AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT This Amendment No. 2 (this “Amendment”) to the Fifth Amended and Restated Registration Rights Agreement, dated August 9, 2013 (the “Registration Rights Agreement”), by and among the Company and the Holders (as defined therein) is entered into as of the 14th day of July, 2016 by and among Argos Therapeutics, Inc

August 15, 2016 EX-4.2

AMENDMENT NO. 2 TO FIFTH AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT

Exhibit 4.2 AMENDMENT NO. 2 TO FIFTH AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT This Amendment No. 2 (this “Amendment”) to the Fifth Amended and Restated Registration Rights Agreement, dated August 9, 2013 (the “Registration Rights Agreement”), by and among the Company and the Holders (as defined therein) is entered into as of the 14th day of July, 2016 by and among Argos Therapeutics, Inc

August 15, 2016 EX-10.3

FIFTH AMENDMENT TO LEASE AGREEMENT AND THIRD AMENDMENT TO PURCHASE AND SALE AGREEMENT

Exhibit 10.3 EXECUTION COPY FIFTH AMENDMENT TO LEASE AGREEMENT AND THIRD AMENDMENT TO PURCHASE AND SALE AGREEMENT THIS FIFTH AMENDMENT TO LEASE AGREEMENT AND THIRD AMENDMENT TO PURCHASE AND SALE AGREEMENT (this “Omnibus Amendment”), dated effective as of July 1, 2016, by and between TKC LXXII, LLC, a North Carolina limited liability company (“TKC”), and ARGOS THERAPEUTICS, INC., a Delaware corpora

August 15, 2016 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q _________________

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2016 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS THERAPEUTICS, INC. (Exact name of regis

August 12, 2016 CORRESP

Argos Therapeutics ESP

SEC Letter August 12, 2016 Via EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.

August 12, 2016 CORRESP

Argos Therapeutics ESP

SEC Letter August 12, 2016 Via EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.

August 10, 2016 EX-99.1

Argos Therapeutics Reports Second Quarter 2016 Financial Results and Recent Operational Highlights - Independent Data Monitoring Committee Recommended Continuation of Phase 3 ADAPT Trial of AGS-003 in Metastatic Renal Cell Carcinoma - - Closed on $29

EdgarFiling EXHIBIT 99.1 Argos Therapeutics Reports Second Quarter 2016 Financial Results and Recent Operational Highlights - Independent Data Monitoring Committee Recommended Continuation of Phase 3 ADAPT Trial of AGS-003 in Metastatic Renal Cell Carcinoma - - Closed on $29.8 million Second Tranche of March 2016 Financing - - Raised Gross Proceeds of $50.0 million in Follow-on Offering - - Entere

August 10, 2016 8-K

Argos Therapeutics FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event Reported): August 10, 2016 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporation) (Commission Fi

July 29, 2016 EX-99.1

Argos Therapeutics Announces Pricing of $50 Million Public Offering of Common Stock and Warrants

EX-99.1 Exhibit 99.1 Argos Therapeutics Announces Pricing of $50 Million Public Offering of Common Stock and Warrants DURHAM, N.C., July 28, 2016 ? Argos Therapeutics, Inc. (Nasdaq: ARGS) (?Argos?), an immuno-oncology company focused on the development and commercialization of individualized immunotherapies for the treatment of cancer based on the Arcelis? technology platform, today announced the

July 29, 2016 EX-4.1

WARRANT AGREEMENT

EX-4.1 Exhibit 4.1 WARRANT AGREEMENT WARRANT AGREEMENT, dated as of , 2016 (the ?Agreement?), by and among Argos Therapeutics, Inc., a Delaware corporation (the ?Company?), Computershare Inc., a Delaware corporation (?Computershare?), and its wholly-owned subsidiary, Computershare Trust Company, N.A., a federally chartered trust company (the ?Trust Company? and collectively with Computershare, ?Wa

July 29, 2016 EX-1.1

9,090,909 Shares of Common Stock Warrants to Purchase 6,818,181 Shares of Common Stock Argos Therapeutics, Inc. UNDERWRITING AGREEMENT

EX-1.1 Exhibit 1.1 9,090,909 Shares of Common Stock and Warrants to Purchase 6,818,181 Shares of Common Stock Argos Therapeutics, Inc. UNDERWRITING AGREEMENT July 28, 2016 STIFEL, NICOLAUS & COMPANY, INCORPORATED JMP Securities LLC As Representatives of the several Underwriters named in Schedule I hereto c/o Stifel, Nicolaus & Company, Incorporated 787 7th Avenue, 11th Floor New York, New York 100

July 29, 2016 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): July 28, 2016 ARGOS THERAPEUTICS, INC.

July 29, 2016 424B5

9,090,909 Shares of Common Stock Warrants to Purchase up to 6,818,181 Shares of Common Stock $5.50 per share and accompanying warrant

Prospectus Supplement Table of Contents As Filed Pursuant to Rule 424(b)(5) Registration No.

July 28, 2016 FWP

ARGOS THERAPEUTICS, INC. 9,090,909 Shares of Common Stock and Warrants to Purchase 6,818,181 Shares of Common Stock

FWP Filed Pursuant to Rule 433 of the Securities Act of 1933, as amended Issuer Free Writing Prospectus dated July 28, 2016 Relating to Preliminary Prospectus dated July 27, 2016 Registration No.

July 27, 2016 424B5

SUBJECT TO COMPLETION, DATED JULY 27, 2016

Preliminary Prospectus Supplement Table of Contents As Filed Pursuant to Rule 424(b)(5) Registration No.

July 27, 2016 8-K

Argos Therapeutics FORM 8-K (Current Report/Significant Event)

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): July 27, 2016 ARGOS THERAPEUTICS, INC.

July 22, 2016 S-3

Argos Therapeutics FORM S-3

As filed with the Securities and Exchange Commission on July 22, 2016 Registration No.

July 12, 2016 SC 13D/A

ARGS / Argos Therapeutics, Inc. / Pharmstandard International S.A. - SCHEDULE 13D - AMENDMENT NO. 2 FOR ARGOS THERAPEUTICS, INC. BY PHARMSTANDARD INTERNATIONAL S.A. Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 2)* ARGOS THERAPEUTICS, INC. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 040221 103 (CUSIP Number) Pharmstandard International S.A. 10a, rue Henri Schnadt Luxembourg, N4 L-2530 +352 24840131 (Name, Address and Tel

July 11, 2016 8-K

Argos Therapeutics FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 30, 2016 Argos Therapeutics, Inc.

July 11, 2016 EX-10.1

ARGOS THERAPEUTICS, INC. 4233 TECHNOLOGY DRIVE DURHAM, NC 27704

EX-10.1 2 exh101.htm EXHIBIT 10.1 Exhibit 10.1 ARGOS THERAPEUTICS, INC. 4233 TECHNOLOGY DRIVE DURHAM, NC 27704 July 1, 2016 VIA email Richard D. Katz 209 Sierra Drive Chapel Hill, NC 27514 Dear Rich: I am pleased to extend to you this offer of employment with Argos Therapeutics, Inc. (“Argos Therapeutics”) by way of this offer letter (the “Offer Letter”). We at Argos Therapeutics are excited about

July 11, 2016 EX-99.1

Dr. Richard D. Katz Joins Argos Therapeutics as Chief Financial Officer

EdgarFiling EXHIBIT 99.1 Dr. Richard D. Katz Joins Argos Therapeutics as Chief Financial Officer DURHAM, N.C., July 11, 2016 (GLOBE NEWSWIRE) - Argos Therapeutics, Inc. (Nasdaq:ARGS), an immuno-oncology company focused on the development and commercialization of truly individualized immunotherapies for the treatment of cancer and infectious diseases based on the Arcelis® technology platform, today

June 29, 2016 8-K

Other Events

8-K 1 f8k062816.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 29, 2016 ARGOS THERAPEUTICS, INC. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of In

June 13, 2016 8-K

Argos Therapeutics FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 10, 2016 ARGOS THERAPEUTICS, INC. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporation) (Commission File

May 27, 2016 SC 13D/A

ARGS / Argos Therapeutics, Inc. / Pharmstandard International S.A. - SC 13D/A Activist Investment

SC 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* ARGOS THERAPEUTICS, INC. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 040221 103 (CUSIP Number) Pharmstandard International S.A 10a, rue Henri Schnadt Luxembourg, L-2530 +352 24840131 (Name, Address

May 27, 2016 EX-2

SALE AND PURCHASE AGREEMENT

EX-2 Exhibit 2 SALE AND PURCHASE AGREEMENT This SALE AND PURCHASE AGREEMENT (this “Agreement”), dated as of May 19, 2016 (the “Effective Date”), by and between Pharmstandard International S.

May 25, 2016 CORRESP

Argos Therapeutics ESP

May 25, 2016 Via EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.

May 16, 2016 S-8

Argos Therapeutics FORM S-8

S-8 1 s8051616.htm FORM S-8 As filed with the Securities and Exchange Commission on May 16, 2016 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 56-2110007 (State or Other Jurisdiction of Incorporatio

May 16, 2016 EX-99.1

ARGOS THERAPEUTICS, INC. Nonstatutory Stock Option Agreement

Exhibit 99.1 ARGOS THERAPEUTICS, INC. Nonstatutory Stock Option Agreement 1. Grant of Option. This agreement evidences the grant by Argos Therapeutics, Inc., a Delaware corporation (the ?Company?), on January 19, 2016 (the ?Grant Date?) to Lee Allen, an employee of the Company (the ?Participant?), of an option to purchase, in whole or in part, on the terms provided herein, a total of 300,000 share

May 16, 2016 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2016 or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS THERAPEUTICS, INC. (Exact name of regi

May 16, 2016 EX-10.1

ARGOS THERAPEUTICS, INC. 4233 TECHNOLOGY DRIVE DURHAM, NC 27704

Exhibit 10.1 ARGOS THERAPEUTICS, INC. 4233 TECHNOLOGY DRIVE DURHAM, NC 27704 December 2, 2015 VIA email Lee F. Allen 3 Paniolo Road Ladera Ranch, CA 92656 Dear Lee: I am pleased to extend to you this offer of employment with Argos Therapeutics, Inc. (“Argos Therapeutics”) by way of this offer letter (the “Offer Letter”). We at Argos Therapeutics are excited about the challenges and opportunities t

May 13, 2016 S-3

Argos Therapeutics S-3

As filed with the Securities and Exchange Commission on May 13, 2016 Registration No.

May 12, 2016 EX-99.1

Argos Therapeutics Reports First Quarter 2016 Financial Results and Operational Highlights - Entered into Equity Financing for Up to $60 million - - Phase 3 ADAPT trial of AGS-003 in Metastatic Renal Cell Carcinoma On Track for Upcoming Review by Ind

EdgarFiling EXHIBIT 99.1 Argos Therapeutics Reports First Quarter 2016 Financial Results and Operational Highlights - Entered into Equity Financing for Up to $60 million - - Phase 3 ADAPT trial of AGS-003 in Metastatic Renal Cell Carcinoma On Track for Upcoming Review by Independent Data Monitoring Committee - - Dr. Lee F. Allen joined as Chief Medical Officer - - Investigator-initiated Phase 2 St

May 12, 2016 8-K

Argos Therapeutics FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event Reported): May 12, 2016 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporation) (Commission File

April 29, 2016 DEFA14A

Argos Therapeutics DEFINITIVE ADDITIONAL MATERIALS

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of

April 29, 2016 DEF 14A

Argos Therapeutics DEFINITIVE PROXY STATEMENT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of

April 19, 2016 8-K

Argos Therapeutics FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 15, 2016 Argos Therapeutics, Inc.

April 15, 2016 PRE 14A

Argos Therapeutics PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: x Preliminary Proxy Statement ? Confidential, for Use of

April 4, 2016 8-K/A

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K/A Amendment No. 1 CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 29, 2016 ARGOS THERAPEUTICS, INC. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporatio

April 4, 2016 EX-99.2

Partial Transcript of Conference Call held on March 29, 2016

Exhibit 99.2 Partial Transcript of Conference Call held on March 29, 2016 Lori Harrelson - Argos Therapeutics, Inc. - VP, Finance Thank you, Charles. Our cash, cash equivalents and short-term investments as of December 31, 2015 totaled $7.2 million compared to $56.2 million as of December 31, 2014. The decrease results primarily from cash used to fund our Phase 3 ADAPT clinical trial and our comme

March 31, 2016 S-8

Argos Therapeutics FORM S-8

As filed with the Securities and Exchange Commission on March 31, 2016 Registration No.

March 30, 2016 EX-10.31

ARGOS THERAPEUTICS, INC. 4233 TECHNOLOGY DRIVE DURHAM, NC 27704

Exhibit 10.31 ARGOS THERAPEUTICS, INC. 4233 TECHNOLOGY DRIVE DURHAM, NC 27704 January 30, 2015 VIA email Joan Winterbottom 6986 Phillips Mill Road New Hope, PA 18938 Dear Joan: I am pleased to extend to you this offer of employment with Argos Therapeutics, Inc. (?Argos Therapeutics?) by way of this offer letter (the ?Offer Letter?). We at Argos Therapeutics are excited about the challenges and opp

March 30, 2016 EX-10.30

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions.

Exhibit 10.30 Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. MASTER PROCESS DEVELOPMENT AND SUPPLY AGREEMENT This Master Process Development and Supply Agreement (?Agreement?) by and between CELLSCRIPT, LLC (?CELLSCRIPT?), a Wisconsin limited liability company located at 726 Post Road, Madison, Wisconsin 53713, an

March 30, 2016 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2015 or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS THERAPEUTICS, INC. (Exact name of registran

March 29, 2016 EX-99.1

Argos Therapeutics Reports Fourth Quarter and Full-Year 2015 Financial Results and Operational Highlights - Completed Patient Enrollment in Pivotal Phase 3 ADAPT Clinical Trial of AGS-003 in July 2015 – - Independent Data Monitoring Committee (IDMC)

EdgarFiling EXHIBIT 99.1 Argos Therapeutics Reports Fourth Quarter and Full-Year 2015 Financial Results and Operational Highlights - Completed Patient Enrollment in Pivotal Phase 3 ADAPT Clinical Trial of AGS-003 in July 2015 ? - Independent Data Monitoring Committee (IDMC) Recommended Continuation of Pivotal Phase 3 ADAPT Clinical Trial of AGS-003 Following Data Reviews in June and December 2015

March 29, 2016 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

8-K 1 f8k032916.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 29, 2016 ARGOS THERAPEUTICS, INC. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of I

March 22, 2016 SC 13D

ARGS / Argos Therapeutics, Inc. / Pharmstandard International S.A. - SCHEDULE 13D BY ARGOS THERAPEUTICS, INC. BY PHARMSTANDARD INTERNATIONAL S.A. Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. )* ARGOS THERAPEUTICS, INC. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 040221 103 (CUSIP Number) Pharmstandard International S.A 10a, rue Henri Schnadt Luxembourg, N4 L-2530 +352 24840131 (Name, Address and Telep

March 7, 2016 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Other Events

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 3, 2016 ARGOS THERAPEUTICS, INC.

March 7, 2016 EX-10.3

REGISTRATION RIGHTS AGREEMENT

EX-10.3 Exhibit 10.3 REGISTRATION RIGHTS AGREEMENT This REGISTRATION RIGHTS AGREEMENT (this ?Agreement?) is made and entered into as of March 4, 2016 by and among Argos Therapeutics, Inc., a Delaware corporation (the ?Company?), and the ?Investors? named in that certain Securities Purchase Agreement by and among the Company and the Investors (the ?Purchase Agreement?). Capitalized terms used herei

March 7, 2016 EX-10.2

Void after 5:00 p.m. (New York time) on the [●] day of March, 2021. Number of Warrant Shares: Warrant No.

EX-10.2 Exhibit 10.2 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE ?SECURITIES ACT?), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIV

March 7, 2016 EX-10.1

SECURITIES PURCHASE AGREEMENT

EX-10.1 Exhibit 10.1 SECURITIES PURCHASE AGREEMENT This SECURITIES PURCHASE AGREEMENT (this ?Agreement?) is made and entered into as of March 4, 2016 by and among Argos Therapeutics, Inc., a Delaware corporation (the ?Company?), and the Investors identified on Exhibit A attached hereto (each an ?Investor? and collectively the ?Investors?). RECITALS A. The Investors wish to purchase from the Compan

March 7, 2016 EX-99.1

Argos Therapeutics Announces Financing of up to $60 Million

EX-99.1 5 d129578dex991.htm EX-99.1 Exhibit 99.1 Argos Therapeutics Announces Financing of up to $60 Million DURHAM, N.C., March 7, 2016 – Argos Therapeutics, Inc. (Nasdaq: ARGS) (“Argos”), an immuno-oncology company focused on the development and commercialization of truly individualized immunotherapies for the treatment of cancer based on the Arcelis® technology platform, today announced that it

February 17, 2016 SC 13G

ARGS / Argos Therapeutics, Inc. / Forbion Co-Investment II Cooperatief U.A. - SC 13G Passive Investment

SC 13G 1 d143634dsc13g.htm SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* ARGOS THERAPEUTICS INC. (Name of Issuer) COMMON STOCK, PAR VALUE $0.001 PER SHARE (Title of Class of Securities) 040221 103 (CUSIP Number) 31 DECEMBER 2015 (Date of Event Which Requires Filing of this Statement) Check the

February 17, 2016 SC 13G

ARGS / Argos Therapeutics, Inc. / Cooperatieve AAC LS U.A. - SC 13G Passive Investment

SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* ARGOS THERAPEUTICS INC. (Name of Issuer) COMMON STOCK, PAR VALUE $0.001 PER SHARE (Title of Class of Securities) 040221 103 (CUSIP Number) 31 DECEMBER 2015 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designa

February 17, 2016 EX-99.1

JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(k)

EX-99.1 Exhibit 99.1 CUSIP No. 040221 103 13G Page 8 of 8 Pages JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(k) The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing addit

February 17, 2016 EX-99.1

JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(k)

EX-99.1 CUSIP No. 040221 103 13G Page 8 of 8 Pages Exhibit 99.1 JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(k) The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing addit

February 16, 2016 SC 13G

ARGS / Argos Therapeutics, Inc. / TVM V LIFE SCIENCE VENTURES GMBH & CO KG - ARGOS THERAPEUTICS, INC. Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULE 13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2 (Amendment No. ) Argos Therapeutics, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 040221103 (CUSIP Number) December 31, 2015 (Date of Event which Requires

January 14, 2016 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 8, 2016 Argos Therapeutics, Inc.

December 29, 2015 8-K

Argos Therapeutics FORM 8-K (Current Report/Significant Event)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 22, 2015 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporation) (Commission

November 16, 2015 EX-99

Argos Therapeutics Reports Third Quarter 2015 Financial Results and Operational Highlights

Argos Therapeutics Reports Third Quarter 2015 Financial Results and Operational Highlights EXHIBIT 99.

November 16, 2015 EX-10.1

SOC 25.55

Exhibit 10.1 Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. OMB Approval 2700-0042 1. CONTRACT ID CODE PAGE OF PAGES AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT 1 12 2. AMENDMENT/MODIFICATION NO. 3. EFFECTIVE DATE 4. REQUISITION/PURCHASE REQ. NO. 5. PROJECT NO. (If applicable) Eleven (11) See Block 16C. 350

November 16, 2015 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

Form 8-K Filing UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 16, 2015 Argos Therapeutics, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35443 56-2110007 (State or other jurisdiction of incorpo

November 16, 2015 S-8

Argos Therapeutics FORM S-8

As filed with the Securities and Exchange Commission on November 16, 2015 Registration No.

November 16, 2015 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q _________________

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2015 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS THERAPEUTICS, INC. (Exact name of

September 23, 2015 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

Form 8-K Filing UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 18, 2015 Argos Therapeutics, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35443 56-2110007 (State or other jurisdiction of incorp

September 23, 2015 EX-99

Robert F. Carey Appointed to the Board of Directors of Argos Therapeutics

Robert F. Carey Appointed to the Board of Directors of Argos Therapeutics EXHIBIT 99.1 Robert F. Carey Appointed to the Board of Directors of Argos Therapeutics DURHAM, N.C., Sept. 23, 2015 (GLOBE NEWSWIRE) - Argos Therapeutics Inc. (Nasdaq:ARGS) ("Argos"), an immuno-oncology company focused on the development and commercialization of fully individualized immunotherapies based on the Arcelis? tech

August 14, 2015 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q _________________

10-Q 1 gff10q081415.htm FORM 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2015 or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS THERA

August 12, 2015 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

8-K 1 document.htm FORM 8-K FILING DOCUMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2015 Argos Therapeutics, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35443 56-2110007 (State or oth

August 12, 2015 EX-99

Argos Therapeutics Reports Second Quarter 2015 Financial Results and Operational Highlights

Argos Therapeutics Reports Second Quarter 2015 Financial Results and Operational Highlights EXHIBIT 99.

June 22, 2015 8-K

Argos Therapeutics FORM 8-K (Current Report/Significant Event)

f8k062215.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 17, 2015 ARGOS THERAPEUTICS, INC. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Incorporation) (C

May 18, 2015 DEF 14A

Argos Therapeutics DEFINITIVE PROXY STATEMENT

def14a051815.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confide

May 15, 2015 EX-10.2

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions.

Exhibit 10.2 Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. Execution Copy LICENSE AGREEMENT by and between ARGOS THERAPEUTICS, INC. and LUMMY (HONG KONG) CO., LTD LICENSE AGREEMENT THIS LICENSE AGREEMENT (the ?Agreement?), effective as of the Effective Date (hereinafter defined), is by and between Argos Therapeut

May 15, 2015 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

10-Q 1 f10q051515.htm FORM 10-Q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2015 or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS THERAP

May 14, 2015 EX-99

Argos Therapeutics Reports First Quarter 2015 Financial Results and Operational Highlights

Argos Therapeutics Reports First Quarter 2015 Financial Results and Operational Highlights EXHIBIT 99.

May 14, 2015 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

Form 8-K Filing UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) May 14, 2015 Argos Therapeutics, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35443 56-2110007 (State or other jurisdiction of incorporation

May 8, 2015 EX-4.5

Form of Senior Note (FACE OF SECURITY)

Exhibit 4.5 Form of Senior Note (FACE OF SECURITY) [Each Global Security shall bear substantially the following legend: UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE REGISTERED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE OF THE

May 8, 2015 EX-1.2

ARGOS THERAPEUTICS, INC. Common Stock (par value $0.001 per share) SALES AGREEMENT

Exhibit 1.2 ARGOS THERAPEUTICS, INC. Common Stock (par value $0.001 per share) SALES AGREEMENT May 8, 2015 Cowen and Company, LLC 599 Lexington Avenue New York, NY 10022 Ladies and Gentlemen: Argos Therapeutics, Inc. (the “Company”), confirms its agreement (this “Agreement”) with Cowen and Company, LLC (“Cowen”), as follows: 1. Issuance and Sale of Shares. The Company agrees that, from time to tim

May 8, 2015 EX-4.6

Form of Subordinated Note (FACE OF SECURITY)

EX-4.6 6 exh46.htm EXHIBIT 4.6 Exhibit 4.6 Form of Subordinated Note (FACE OF SECURITY) [Each Global Security shall bear substantially the following legend: UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE REGISTERED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE

May 8, 2015 EX-4.3

ARGOS THERAPEUTICS, INC. Dated as of _______________ SENIOR DEBT SECURITIES CROSS-REFERENCE TABLE(1)

Exhibit 4.3 ARGOS THERAPEUTICS, INC. and Trustee INDENTURE Dated as of SENIOR DEBT SECURITIES CROSS-REFERENCE TABLE(1) Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 6.09 310(b) 6.08 6.10 310(c) Inapplicable 311(a) 6.13 311(b) 6.13 311(c) Inapplicable 312(a) 4.01 4.04 312(b) 4.04(c) 312(c) 4.04(c) 313(a) 4.03 313(b) 4.03 313(c) 4.03 313(d) 4.03 314(a) 4.02 314(b) In

May 8, 2015 S-3

As filed with the Securities and Exchange Commission on May 8, 2015

S-3 1 fs3050415.htm FORM S-3 As filed with the Securities and Exchange Commission on May 8, 2015 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 ARGOS THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 56-2110007 (State or other jurisdiction of incorporatio

May 8, 2015 EX-4.4

ARGOS THERAPEUTICS, INC. Dated as of _______________ SUBORDINATED DEBT SECURITIES

Exhibit 4.4 ARGOS THERAPEUTICS, INC. and Trustee INDENTURE Dated as of SUBORDINATED DEBT SECURITIES CROSS-REFERENCE TABLE(1) Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 6.09 310(b) 6.08 6.10 310(c) Inapplicable 311(a) 6.13 311(b) 6.13 311(c) Inapplicable 312(a) 4.01 4.04 312(b) 4.04(c) 312(c) 4.04(c) 313(a) 4.03 313(b) 4.03 313(c) 4.03 313(d) 4.03 314(a) 4.02 314

May 8, 2015 EX-12.1

RATIOS OF EARNINGS TO FIXED CHARGES AND RATIOS OF EARNINGS TO COMBINED FIXED CHARGES AND PREFERRED STOCK DIVIDENDS

Exhibit 12.1 RATIOS OF EARNINGS TO FIXED CHARGES AND RATIOS OF EARNINGS TO COMBINED FIXED CHARGES AND PREFERRED STOCK DIVIDENDS The following table sets forth our ratio of earnings to fixed charges and ratios of earnings to combined fixed charges and preferred stock dividends for each of the periods indicated. You should read this table in conjunction with the financial statements and notes incorp

April 13, 2015 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities

8-K 1 f8k041315.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 7, 2015 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of Inco

March 31, 2015 EX-10.27

Confidential Materials omitted and filed separately with the

Confidential Materials omitted and filed separately with the Exhibit 10.27 Securities and Exchange Commission. Double asterisks denote omissions. DEVELOPMENT AGREEMENT This Development Agreement (the ?Agreement?) is entered by and between SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION, a California corporation having an office at 1199 South Chillicothe Road, Aurora, OH 44202 (?SGPPL?), and ARGOS TH

March 31, 2015 EX-21.1

Subsidiaries of the Registrant

Exhibit 21.1 Subsidiaries of the Registrant Name Jurisdiction DC Bio Corp. Nova Scotia, Canada

March 31, 2015 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

10-K 1 f10k033115.htm FORM 10-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2014 or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS THERAPEUTIC

March 31, 2015 EX-10.29

Confidential Materials omitted and filed separately with the

Confidential Materials omitted and filed separately with the Exhibit 10.29 Securities and Exchange Commission. Double asterisks denote omissions. NOVATED, AMENDED AND RESTATED LICENSE AGREEMENT by and between ARGOS THERAPEUTICS, INC., MEDINET CO., LTD. and MEDCELL CO., LTD. NOVATED, AMENDED AND RESTATED LICENSE AGREEMENT THIS NOVATED, AMENDED AND RESTATED LICENSE AGREEMENT (the ?Agreement?), effec

March 30, 2015 EX-99

Argos Therapeutics Reports Fourth Quarter and Year-End 2014 Financial Results

Argos Therapeutics Reports Fourth Quarter and Year-End 2014 Financial Results EXHIBIT 99.

March 30, 2015 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

Form 8-K Filing UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) March 30, 2015 Argos Therapeutics, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35443 56-2110007 (State or other jurisdiction of incorporati

March 16, 2015 8-K

Entry into a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 10, 2015 Argos Therapeutics, Inc.

March 4, 2015 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 25, 2015 Argos Therapeutics, Inc.

February 20, 2015 EX-10.1

PURCHASE AND SALE AGREEMENT TKC LXXII, LLC, a North Carolina limited liability company, (the “Seller”) ARGOS THERAPEUTICS, INC., a Delaware corporation (the “Buyer”) PURCHASE AND SALE AGREEMENT

Exhibit 10.1 EXECUTION COPY PURCHASE AND SALE AGREEMENT BETWEEN TKC LXXII, LLC, a North Carolina limited liability company, (the “Seller”) AND ARGOS THERAPEUTICS, INC., a Delaware corporation (the “Buyer”) PURCHASE AND SALE AGREEMENT THIS PURCHASE AND SALE AGREEMENT (this “Agreement”) is made and entered into this 16 day of February, 2015 (the “Effective Date”), by and between TKC LXXII, LLC, a No

February 20, 2015 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 16, 2015 Argos Therapeutics, Inc.

February 17, 2015 SC 13G

ARGS / Argos Therapeutics, Inc. / Cooperatieve AAC LS U.A. - SC13G Passive Investment

SC13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* ARGOS THERAPEUTICS INC. (Name of Issuer) COMMON STOCK, PAR VALUE $0.001 PER SHARE (Title of Class of Securities) 040221 103 (CUSIP Number) 31 DECEMBER 2014 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designat

February 13, 2015 SC 13G

ARGS / Argos Therapeutics, Inc. / Forbion Co-Investment II Cooperatief U.A. - SC13G Passive Investment

SC13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* ARGOS THERAPEUTICS INC. (Name of Issuer) COMMON STOCK, PAR VALUE $0.001 PER SHARE (Title of Class of Securities) 040221 103 (CUSIP Number) 31 DECEMBER 2014 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designat

February 12, 2015 SC 13G

ARGS / Argos Therapeutics, Inc. / Pharmstandard International S.A. - SCHEDULE 13G Passive Investment

SC 13G 1 d869934dsc13g.htm SCHEDULE 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 ARGOS THERAPEUTICS, INC. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 040221 103 (CUSIP Number) December 31, 2014 (Date of Event Which Requires Filing of this Statement) Check the appropria

February 12, 2015 EX-99.1

SCHEDULE 13G CUSIP No. 040221 103 Page 8 of 8

EX-99.1 SCHEDULE 13G CUSIP No. 040221 103 Page 8 of 8 Exhibit 99.1 JOINT FILING AGREEMENT We, the undersigned, hereby express our agreement that the attached Schedule 13G is, and any further amendments thereto signed by each of the undersigned shall be, filed on behalf of us pursuant to and in accordance with the provisions of Rule 13d-1(k) under the Securities Exchange Act of 1934. This agreement

January 9, 2015 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) January 9, 2015 Argos Therapeutics, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35443 56-2110007 (State or other jurisdiction of incorporation) (Commission

January 9, 2015 EX-99

Argos Therapeutics Provides Update on Clinical Research for Investigational Fully Personalized Immunotherapy for the Treatment of HIV

EXHIBIT 99.1 Argos Therapeutics Provides Update on Clinical Research for Investigational Fully Personalized Immunotherapy for the Treatment of HIV Findings from Phase 2b trial support clinical development of AGS-004 in adult eradication and pediatric studies. Company to host conference call and webcast today at 8:30 a.m. ET. DURHAM, N.C., Jan. 9, 2015 (GLOBE NEWSWIRE) - Argos Therapeutics Inc. (Na

January 7, 2015 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) January 5, 2015 Argos Therapeutics, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35443 56-2110007 (State or other jurisdiction of incorporation) (Commission

January 7, 2015 EX-99

Argos Therapeutics and Saint-Gobain Announce Agreement for Production of Disposables Used in Automated Manufacturing of Fully Personalized Immunotherapies

EXHIBIT 99.1 Argos Therapeutics and Saint-Gobain Announce Agreement for Production of Disposables Used in Automated Manufacturing of Fully Personalized Immunotherapies Collaboration Will Support Commercial Production of Argos Immunotherapies Based on the Arcelis(R) Technology Platform DURHAM, N.C. and AURORA, Ohio, Jan. 6, 2015 (GLOBE NEWSWIRE) - Argos Therapeutics Inc. (Nasdaq:ARGS) ("Argos"), a

December 11, 2014 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

8-K 1 f8k121114.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 5, 2014 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of I

November 14, 2014 EX-10.5

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions.

EX-10.5 2 exh105.htm EXHIBIT 10.5 Exhibit 10.5 Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. Development Agreement Argos Therapeutics, Inc. (Argos) Invetech Pty Ltd (Invetech) Development Agreement Details 4 Agreed terms 5 1. Defined terms & interpretation 5 2. Development of the Production System 11 3. Prototype

November 14, 2014 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2014 or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 001-35443 ARGOS THERAPEUTICS, INC. (Exact name of

November 14, 2014 EX-10.6

EX-10.6

Exhibit 10.6

November 14, 2014 EX-10.7

EX-10.7

Exhibit 10.7

November 13, 2014 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 12, 2014 Argos Therapeutics, Inc.

November 13, 2014 EX-99.1

Argos Therapeutics Reports Third Quarter 2014 Financial Results and Operational Highlights

EXHIBIT 99.1 Argos Therapeutics Reports Third Quarter 2014 Financial Results and Operational Highlights Conference Call and Webcast Today, November 13th, at 4:30 p.m. ET DURHAM, N.C., Nov. 13, 2014 (GLOBE NEWSWIRE) - Argos Therapeutics, Inc. (Nasdaq:ARGS), a biopharmaceutical company focused on the development and commercialization of fully personalized immunotherapies for the treatment of cancer

November 13, 2014 EX-99.2

Philippe Van Holle Joins Argos Therapeutics Board of Directors

EXHIBIT 99.2 Philippe Van Holle Joins Argos Therapeutics Board of Directors DURHAM, N.C., Nov. 13, 2014 (GLOBE NEWSWIRE) - Argos Therapeutics, Inc. (Nasdaq:ARGS) ("Argos"), a biopharmaceutical company focused on the development and commercialization of fully personalized immunotherapies for the treatment of cancer and infectious diseases using its Arcelis® technology platform, today announced the

November 4, 2014 8-K

Entry into a Material Definitive Agreement

8-K 1 f8k110414.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): October 29, 2014 Argos Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-35443 56-2110007 (State or Other Jurisdiction of I

October 31, 2014 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): October 29, 2014 Argos Therapeutics, Inc.

October 3, 2014 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

8-K 1 document.htm FORM 8-K FILING DOCUMENT UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) October 3, 2014 Argos Therapeutics, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35443 56-2110007 (State or othe

October 3, 2014 EX-99

Argos Therapeutics Announces Plans for New Manufacturing Facility in Research Triangle Park Area in Durham, North Carolina

EXHIBIT 99.1 Argos Therapeutics Announces Plans for New Manufacturing Facility in Research Triangle Park Area in Durham, North Carolina State of the Art Facility Planned for Automated Production of Arcelis® Personalized Immunotherapies Project Supported by $9.5 Million in Incentives From State of North Carolina, Durham County and City of Durham DURHAM, N.C., Oct. 3, 2014 (GLOBE NEWSWIRE) - Argos T

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