IVEVF / Inventiva S.A. - Документы SEC, Годовой отчет, Доверенное заявление

Инвентива СА
US ˙ OTCPK ˙ FR0013233012

Основная статистика
CIK 1756594
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Inventiva S.A.
SEC Filings (Chronological Order)
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July 29, 2025 EX-99.1

Inventiva Reports Preliminary 2025 First-Half Financial Information1

EXHIBIT 99.1 Inventiva Reports Preliminary 2025 First-Half Financial Information1 Cash and cash equivalents at €122.1 million and €24.6 million in short-term deposits2 as of June 30, 2025 Revenues of €4.5 million recorded in H1 2025 Daix (France), New York City (New York, United States), July 29, 2025 – Inventiva (Euronext Paris and Nasdaq: IVA) (“Inventiva” or the “Company”), a clinical-stage bio

July 29, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2025 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2025 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

July 9, 2025 EX-99.1

Inventiva names Jason Campagna as President of R&D and Chief Medical Officer and Martine Zimmermann as Executive Vice President of Regulatory Affairs and Quality Assurance

EXHIBIT 99.1 Inventiva names Jason Campagna as President of R&D and Chief Medical Officer and Martine Zimmermann as Executive Vice President of Regulatory Affairs and Quality Assurance Jason Campagna, MD, PhD, joins Inventiva as President of R&D and Chief Medical Officer, succeeding Pierre Broqua, PhD, and Michael Cooreman, MD Martine Zimmermann, PharmD, joins as Executive Vice President of Regula

July 9, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2025 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2025 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

July 7, 2025 EX-99.1

Inventiva receives $10 million milestone payment from CTTQ

EdgarFiling EXHIBIT 99.1 Inventiva receives $10 million milestone payment from CTTQ Daix (France), New York City (New York, United States), July 7, 2025 – Inventiva (Euronext Paris and Nasdaq: IVA) (“Inventiva” or the “Company”), a clinical-stage biopharmaceutical company focused on the development of oral therapies for the treatment of metabolic dysfunction-associated steatohepatitis (“MASH”), to

July 7, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2025 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2025 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

May 23, 2025 EX-99.1

Inventiva reports 2025 First Quarter Financial Informationˆ

EdgarFiling EXHIBIT 99.1 Inventiva reports 2025 First Quarter Financial Informationˆ Cash and cash equivalents at €67.9 million Daix (France), New York City (New York, United States), May 23, 2025 – Inventiva (Euronext Paris and Nasdaq: IVA) (the “Company”), a clinical-stage biopharmaceutical company focused on the development of oral therapies for the treatment of metabolic dysfunction-associated

May 23, 2025 EX-99.1

Results of the Votes of the Combined Shareholders’ General Meeting of May 22, 2025

EXHIBIT 99.1 Results of the Votes of the Combined Shareholders’ General Meeting of May 22, 2025 Daix (France), New York City (New York, United States), May 23, 2025 – Inventiva (Euronext Paris and Nasdaq: IVA) (the “Company”), a clinical-stage biopharmaceutical company focused on the development of oral therapies for the treatment of metabolic dysfunction-associated steatohepatitis (“MASH”), today

May 23, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and t

May 23, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and t

May 22, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2025 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and t

May 22, 2025 EX-99.1

Description of the Share Repurchase Program Covered by the Liquidity Agreement with Kepler Chevreux

EdgarFiling EXHIBIT 99.1 Description of the Share Repurchase Program Covered by the Liquidity Agreement with Kepler Chevreux Daix, May 22, 2025 Pursuant to Article 241-2 of the AMF General Regulations (Règlement Général de l’Autorité des marchés financiers), the purpose of this description is to present the objectives and terms of the Company’s share repurchase program approved by the Ordinary Gen

May 5, 2025 EX-99.1

Subscription Agreement for [ABSAs]/[PFW-BSAs]

Exhibit 99.1 Subscription Agreement for [ABSAs]/[PFW-BSAs] INVENTIVA S.A. 50, rue de Dijon 21121 Daix France The undersigned, [·] [acting in the name and on behalf of the investment funds it represents or advises listed hereafter] (the “Subscriber”) hereby confirms its agreement with you as follows: 1. This Subscription Agreement (including the annexes attached hereto, the “Agreement”) is made as

May 5, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of May 2025 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of May 2025 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive off

May 5, 2025 EX-99.2

Inventiva secures the €116 million second tranche of its structured financing of up to €348 million

Exhibit 99.2 PRESS RELEASE Inventiva secures the €116 million second tranche of its structured financing of up to €348 million ► Financing follows completion of enrollment of Phase 3 NATiV3 study evaluating lanifibranor in MASH and satisfaction of other specified conditions. Daix (France), New York City (New York, United States), May 5, 2025 – Inventiva (Euronext Paris and Nasdaq: IVA) (“Inventiva

May 2, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of May 2025 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of May 2025 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive off

May 2, 2025 EX-99.1

Société Anonyme with a Board of Directors with a share capital of EUR 956,623.91 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting

Exhibit 99.1 Translation for information purpose only INVENTIVA Société Anonyme with a Board of Directors with a share capital of EUR 956,623.91 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting The shareholders of INVENTIVA (the “Company”) are informed that the ordinary and extraordinary general meeting (the “General Meeting”) will

April 30, 2025 EX-99.1

Statement of total voting rights and shares forming the company’s share capital as of April 11, 2025 Article R. 22-10-23 of the French Commercial Code Market: Euronext Paris ISIN code / Mnemo: FR0013233012 / IVA Web site: www.inventivapharma.com Date

EXHIBIT 99.1 Statement of total voting rights and shares forming the company’s share capital as of April 11, 2025 Article R. 22-10-23 of the French Commercial Code Market: Euronext Paris ISIN code / Mnemo: FR0013233012 / IVA Web site: www.inventivapharma.com Date Number of shares outstanding Total voting rights, gross (1) Total voting rights, net (2) April 11, 2025 95,662,391 108,635,435 108,574,8

April 30, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of April 2025 Commission File Number: 001-3937

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of April 2025 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

April 30, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of April 2025 Commission File Number: 001-3937

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of April 2025 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

April 30, 2025 EX-99.1

Combined General Meeting of May 22, 2025 - Availability of the preparatory documents

EXHIBIT 99.1 Combined General Meeting of May 22, 2025 - Availability of the preparatory documents Daix (France), New York City (New York, United States), April 30, 2025 – Inventiva (Euronext Paris and Nasdaq: IVA), a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of metabolic dysfunction-associated steatohepatitis (“MASH”), al

April 24, 2025 EX-99.2

INVENTIVA S.A. Ordinary and Extraordinary General Meeting of Inventiva S.A. to be held on May 22, 2025 Instructions for beneficial owners of American Depositary Shares (“ADSs”)

Exhibit 99.2 INVENTIVA S.A. Ordinary and Extraordinary General Meeting of Inventiva S.A. to be held on May 22, 2025 Instructions for beneficial owners of American Depositary Shares (“ADSs”) Beneficial owners of ADSs who wish to submit their votes in connection with the General Meeting of Inventiva to be held on May 22, 2025 should consult the voting instruction form delivered to them by The Bank o

April 24, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of April 2025 Commission File Number: 001-3937

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of April 2025 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive o

April 24, 2025 EX-99.1

Copyright © 2025 BetaNXT, Inc. or its affiliates. All Rights Reserved styleIPC Instructions to The Bank of New York, as Depositary (Must be received prior to 12:00 PM Eastern Time May 15, 2025) The undersigned Holder of American Depositary Receipts (

Exhibit 99.1 Copyright © 2025 BetaNXT, Inc. or its affiliates. All Rights Reserved styleIPC Instructions to The Bank of New York, as Depositary (Must be received prior to 12:00 PM Eastern Time May 15, 2025) The undersigned Holder of American Depositary Receipts (“Receipts”) of Inventiva S.A. (the “Company”) hereby requests and instructs The Bank of New York, as Depositary, to vote or cause to be v

April 15, 2025 EX-4.3

Summary of Free Share Plans

Exhibit 4.3 Summary of Free Share Plans Free Shares (actions gratuites) are allotted for free to holders at an issuance price equal to the par value as set forth in the by-laws (€0.01). The issuance of the Free Shares will occur automatically at the end of the vesting period, by way of a capital increase, which will be realized by debiting the unavailable reserve (réserve non disponible) establish

April 15, 2025 EX-2.4

DESCRIPTION OF SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934

Exhibit 2.4 DESCRIPTION OF SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 The following description sets forth certain material terms and provisions of the securities of Inventiva S.A. (“Inventiva,” the “Company,” “we,” “us” and “our”) that are registered under Section 12 of the U.S. Securities Exchange Act of 1934, as amended (the “Exchange Act”). This descrip

April 15, 2025 EX-13.1

Certification by the Principal Executive Officer and Principal Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

Exhibit 13.1 Certification by the Principal Executive Officer and Principal Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 Pursuant to the requirement set forth in Rule 13a-14(b) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), and Section 1350 of Chapter 63 of Title 18 of the United States Code (18

April 15, 2025 EX-11.1

CODE OF MARKET CONDUCT Up to date as of April 18, 2017

Exhibit 11.1 CODE OF MARKET CONDUCT Up to date as of April 18, 2017 Translation for information purposes only TABLE OF CONTENT INTRODUCTION 3 DEFINITIONS 4 1. CONCEPT OF INSIDE INFORMATION 7 2. HANDLING OF INSIDE INFORMATION 7 2.1 Principle of financial disclosure 7 2.2 Insider List Registration 8 3. RULES APPLICABLE TO ANY PERMANENT AND OCCASIONAL INSIDER 9 3.1 General duty of confidentiality 9 3

April 15, 2025 EX-1.1

INVENTIVA Société anonyme à Conseil d’administration with a share capital of €956,623.91 Registered office: 50 Rue de Dijon, 21121, Daix, France Dijon Trade and Companies Register 537 530 255 ARTICLES OF ASSOCIATION UPDATED TO REFLECT THE CHIEF EXECU

Exhibit 1.1 INVENTIVA Société anonyme à Conseil d’administration with a share capital of €956,623.91 Registered office: 50 Rue de Dijon, 21121, Daix, France Dijon Trade and Companies Register 537 530 255 ARTICLES OF ASSOCIATION UPDATED TO REFLECT THE CHIEF EXECUTIVE OFFICER’S DECISIONS OF 19th December 2024 PART I FORM - NAME - OBJECTS - REGISTERED OFFICE - TERM ARTICLE 1. FORM The company (the “C

April 15, 2025 EX-12.2

Certification by the Principal Financial Officer pursuant to Securities Exchange Act Rule 13a-14(a) or Rule 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Exhibit 12.2 Certification by the Principal Financial Officer pursuant to Securities Exchange Act Rule 13a-14(a) or Rule 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 I, Jean Volatier, certify that: 1. I have reviewed this annual report on Form 20-F of Inventiva S.A.; 2. Based on my knowledge, this report does not contain any untrue statement of a material fact or

April 15, 2025 20-F

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 20-F

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 20-F (Mark One) ☐ REGISTRATION STATEMENT PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF

April 15, 2025 EX-4.4

Summary of Stock-Option Plans

Exhibit 4.4 Summary of Stock-Option Plans On December 20, 2024, the Company’s board of directors (the “Board”) granted 12,898,116 stock-options (the “SO 2024-1”) at a price of two euros and thirty-five cents (EUR 2.35) per SO 2024-1, to Mark Pruzanski, the Chairman of the Board of the Company. The SO 2024-1 will vest (but, for the avoidance of doubt, will not become exercisable) on the basis of th

April 15, 2025 EX-12.1

Certification by the Principal Executive Officer pursuant to Securities Exchange Act Rule 13a-14(a) or Rule 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Exhibit 12.1 Certification by the Principal Executive Officer pursuant to Securities Exchange Act Rule 13a-14(a) or Rule 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 I, Frédéric Cren, certify that: 1. I have reviewed this annual report on Form 20-F of Inventiva S.A.; 2. Based on my knowledge, this report does not contain any untrue statement of a material fact or

April 11, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of April 2025 Commission File Number: 001-3937

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of April 2025 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive o

April 11, 2025 EX-99.1

INVENTIVA Société Anonyme with a Board of Directors With a share capital of EUR 956,623.91 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting to the Ordinary and Extraordinary General M

Exhibit 99.1 Translation for information purpose only INVENTIVA Société Anonyme with a Board of Directors With a share capital of EUR 956,623.91 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting to the Ordinary and Extraordinary General Meeting dated May 22, 2025 The shareholders of INVENTIVA (the “Company”) are informed that the or

April 1, 2025 EX-99.1

Inventiva announces completion of enrollment in the Phase 3 NATiV3 clinical trial of lanifibranor in patients with MASH and advanced fibrosis

EXHIBIT 99.1 Inventiva announces completion of enrollment in the Phase 3 NATiV3 clinical trial of lanifibranor in patients with MASH and advanced fibrosis Target enrollment exceeded with 1009 patients randomized in the main cohort and 410 patients in the exploratory cohort Topline results from NATiV3 projected in the second half of 2026 and, if positive, expected to be the basis for submission for

April 1, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of April 2025 Commission File Number: 001-3937

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of April 2025 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

March 26, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of March 2025 Commission File Number: 001-3937

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of March 2025 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

March 26, 2025 EX-99.1

Inventiva reports its 2024 full year results and provides a business update

EXHIBIT 99.1 Inventiva reports its 2024 full year results and provides a business update Revenues of €9.2 million for the full year of 2024 Cash and cash equivalents at €96.6 million as of December 31, 2024 First tranche of up to €348 million Structured Financing closed with aggregate gross proceeds of €116 million Last patient screened in the NATiV3 Phase 3 clinical trial of lanifibranor in MASH

February 20, 2025 EX-99.1

Inventiva and Hepalys Pharma, Inc. announce the initiation of the clinical development program of lanifibranor in Japan with the dosing of the first participant in Phase 1 trial

EXHIBIT 99.1 Inventiva and Hepalys Pharma, Inc. announce the initiation of the clinical development program of lanifibranor in Japan with the dosing of the first participant in Phase 1 trial Initiation of the clinical development program of lanifibranor in Japan with the dosing of the first participant in Phase 1 study Positive results could support the initiation of a pivotal Phase 3 trial in pat

February 20, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of February 2025 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of February 2025 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

February 14, 2025 EX-99.1

Joint Filing Agreement

EX-99.1 2 tm256094d1ex-1.htm EXHIBIT 1 Exhibit 1 Joint Filing Agreement In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the undersigned agree to the joint filing on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the ordinary shares of Inventiva S.A. and further agree that this agreement be included as an

February 10, 2025 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of February 2025 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of February 2025 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

February 10, 2025 EX-99.1

Inventiva reports preliminary 2024 fiscal year financial resultsˆ and provides a business update

EXHIBIT 99.1 Inventiva reports preliminary 2024 fiscal year financial resultsˆ and provides a business update Revenues of €9.2 million for the full year of 2024 Cash and cash equivalents at €96.6 million as of December 31, 2024 First tranche of up to €348 million structured financing closed with aggregate gross proceeds of €116 million Last patient screened in the NATiV3 Phase 3 clinical trial of

December 16, 2024 EX-99.2

Inventiva secures €21.4 million and completes the first tranche of the previously announced multi-tranche financing of up to €348 million

Exhibit 99.2 PRESS RELEASE Inventiva secures €21.4 million and completes the first tranche of the previously announced multi-tranche financing of up to €348 million ► Inventiva secures €21.4 million leading to completion of the first tranche of the financing for c. €116 million, part of the multi-tranche equity financing of up to €348 million announced on October 14, 2024. ► Proceeds from the comp

December 16, 2024 EX-99.1

Subscription Agreement for T1 bis [Shares] [Pre-Funded Warrants]

Exhibit 99.1 Subscription Agreement for T1 bis [Shares] [Pre-Funded Warrants] INVENTIVA S.A. 50, rue de Dijon 21121 Daix France Inventiva S.A., a société anonyme organized under the laws of the French Republic, with a share capital of €870,776.95, consisting of 87,077,695 ordinary shares of €0.01 nominal value each (the “Ordinary Shares” and each, an “Ordinary Share”), and registered with the Comm

December 16, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of December 2024 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of December 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executiv

December 12, 2024 EX-99.1

Results of the votes of the Combined Shareholders’ General Meeting of December 11, 2024

EXHIBIT 99.1 Results of the votes of the Combined Shareholders’ General Meeting of December 11, 2024 Daix (France), New York City (New York, United States), December 11, 2024 – Inventiva (Euronext Paris and Nasdaq: IVA) (the “Company”), a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of metabolic dysfunction-associated steato

December 12, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of December 2024 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of December 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

November 26, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of November 2024 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of November 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executiv

November 26, 2024 EX-99.1

INVENTIVA French société Anonyme with a Board of Directors with a share capital of EUR 870,776.95 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of the combined general meeting of December 11,

Exhibit 99.1 Translation for information purpose only INVENTIVA French société Anonyme with a Board of Directors with a share capital of EUR 870,776.95 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of the combined general meeting of December 11, 2024 The shareholders of INVENTIVA are informed that the Ordinary and Extraordinary General Mee

November 21, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2024 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

November 21, 2024 EX-99.1

Inventiva reports 2024 Third Quarter Financial Information1

EXHIBIT 99.1 Inventiva reports 2024 Third Quarter Financial Information1 Cash and cash equivalents at €13.9 million, as of September 30, 2024. Revenues of €1.3 million for the first nine months of 2024. On July 18, 2024, Inventiva issued royalty certificates for an amount of €20.1 million. Considering the receipt of €94.1 million in gross proceeds from the closing of the first part of the first tr

November 20, 2024 EX-99.1

Combined General Meeting of December 11, 2024 - Availability of the preparatory documents

EXHIBIT 99.1 Combined General Meeting of December 11, 2024 - Availability of the preparatory documents Daix (France), Long Island City (New York, United States), November 20, 2024 – Inventiva (Euronext Paris and Nasdaq: IVA), a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of metabolic dysfunction-associated steatohepatitis (

November 20, 2024 EX-99.1

Statement of total voting rights and shares forming the company’s share capital as of November 4, 2024 Article R. 22-10-23 of the French Commercial Code Market : Euronext Paris ISIN code / Mnemo : FR0013233012 / IVA Web site : www.inventivapharma.com

EXHIBIT 99.1 Statement of total voting rights and shares forming the company’s share capital as of November 4, 2024 Article R. 22-10-23 of the French Commercial Code Market : Euronext Paris ISIN code / Mnemo : FR0013233012 / IVA Web site : www.inventivapharma.com Date Number of Shares Outstanding Total voting rights, gross (1) Total voting rights, net (2) November 4, 2024 87 077 695 100 059 052 99

November 20, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2024 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

November 20, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2024 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

November 15, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2024 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

November 15, 2024 EX-99.1

Inventiva will present data from the final analysis of the Phase 2 study evaluating the combination of lanifibranor with empagliflozin in patients with MASH and T2D at the AASLD The Liver Meeting® late-breaker session

EXHIBIT 99.1 Inventiva will present data from the final analysis of the Phase 2 study evaluating the combination of lanifibranor with empagliflozin in patients with MASH and T2D at the AASLD The Liver Meeting® late-breaker session Data will be presented on Monday, November 18th as a late breaker poster at the American Association for the Study of Liver Diseases (AASLD) The Liver Meeting® 2024 in S

November 14, 2024 EX-99.2

INVENTIVA S.A. Ordinary and Extraordinary General Meeting of Inventiva S.A. to be held on December 11, 2024 Instructions for beneficial owners of American Depositary Shares (“ADSs”)

Exhibit 99.2 INVENTIVA S.A. Ordinary and Extraordinary General Meeting of Inventiva S.A. to be held on December 11, 2024 Instructions for beneficial owners of American Depositary Shares (“ADSs”) Beneficial owners of ADSs who wish to submit their votes in connection with the General Meeting of Inventiva to be held on December 11, 2024 should consult the voting instruction form delivered to them by

November 14, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of November 2024 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of November 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executiv

November 14, 2024 EX-99.1

Inventiva S.A. Joint Ordinary & Extraordinary General Meeting of Shareholders Please make your marks like this: PROPOSAL YOUR VOTE Ordinary Items FOR AGAINST ABSTAIN 1. Appointment of Mr. Mark Pruzanski, as Director of the Company; #P2# #P2# #P2# 2.

Exhibit 99.1 Copyright © 2024 BetaNXT, Inc. or its affiliates. All Rights Reserved styleIPC Instructions to The Bank of New York Mellon, as Depositary (Must be received prior to 12:00 PM Eastern Time December 4, 2024) The undersigned Holder of American Depositary Receipts (“Receipts”) of Inventiva S.A. (the “Company”) hereby requests and instructs The Bank of New York Mellon, as Depositary, to vot

November 4, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of November 2024 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of November 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executiv

November 4, 2024 EX-99.1

INVENTIVA Société Anonyme with a Board of Directors With a share capital of EUR 870,776.95 Registered office: 50, rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Registry of Dijon NOTICE OF MEETING TO THE ORDINARY AND EXTRAORDINARY GENERAL M

Exhibit 99.1 Free translation for information purpose only INVENTIVA Société Anonyme with a Board of Directors With a share capital of EUR 870,776.95 Registered office: 50, rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Registry of Dijon NOTICE OF MEETING TO THE ORDINARY AND EXTRAORDINARY GENERAL MEETING DATED DECEMBER 11, 2024 The shareholders of INVENTIVA (the "Company") are hereby inf

October 30, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of October 2024 Commission File Number: 001-39

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of October 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, a

October 30, 2024 EX-99.1

Inventiva announces the positive recommendation of the fifth DMC of the NATiV3 Phase 3 clinical trial with lanifibranor in patients with MASH

EXHIBIT 99.1 Inventiva announces the positive recommendation of the fifth DMC of the NATiV3 Phase 3 clinical trial with lanifibranor in patients with MASH The Data Monitoring Committee recommended to continue the clinical trial without modification of the current protocol, based on the pre-planned review of safety data. The recommendation was based on the unblinded review by the DMC of safety data

October 21, 2024 SC 13D/A

IVA / Inventiva S.A. - Depositary Receipt (Common Stock) / New Enterprise Associates 17, L.P. - NEW ENTERPRISE ASSOCIATES 17, L.P. -- INVENTIVA S.A. 13D/A(#2) Activist Investment

SC 13D/A 1 nea17-inventiva18892.htm NEW ENTERPRISE ASSOCIATES 17, L.P. - INVENTIVA S.A. 13D/A(#2) UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 2)* Inventiva S.A. (Name of Issuer) Ordinary Shares, €.01 par value per share (Title of Class of Securities) 46124U107 (CUSIP Number) Stephanie Brecher New Ente

October 21, 2024 SC 13D/A

IVA / Inventiva S.A. - Depositary Receipt (Common Stock) / BIOTECHNOLOGY VALUE FUND L P - AMENDMENT NO. 3 TO SCHEDULE 13D Activist Investment

SC 13D/A 1 sc13da307422iva10212024.htm AMENDMENT NO. 3 TO SCHEDULE 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 3)1 Inventiva S.A. (Name of Issuer) Ordinary Shares, nominal value €0.01 per share (

October 15, 2024 EX-99.1

Subscription Agreement for T1 [Shares] [Pre-Funded Warrants]

Exhibit 99.1 Subscription Agreement for T1 [Shares] [Pre-Funded Warrants] INVENTIVA S.A. 50, rue de Dijon 21121 Daix France Inventiva S.A., a société anonyme organized under the laws of the French Republic, with a share capital of €524,771.88, consisting of 52,477,188 ordinary shares of €0.01 nominal value each (the “Ordinary Shares” and each, an “Ordinary Share”), and registered with the Commerce

October 15, 2024 EX-99.4

Inventiva announces financing of up to €348 million to advance the NATiV3 Phase 3 MASH study

Exhibit 99.4 PRESS RELEASE Inventiva announces financing of up to €348 million to advance the NATiV3 Phase 3 MASH study ► Inventiva secures €94.1 million of a multi-tranche equity financing of up to €348 million, subject to satisfaction of specified conditions, from both new and existing investors, and up to $30 million in milestone payments relating to equity financing pursuant to amendment to li

October 15, 2024 EX-99.1

INVENTIVA S.A. A joint-stock company (société anonyme) with a share capital of 524,771.88 euros Registered office: 50, rue de Dijon, 21121 Daix, France Dijon Trade and Companies Register 537 530 255 INTERIM FINANCIAL REPORT FOR THE SIX MONTHS ENDED J

Table of Contents Exhibit 99.1 INVENTIVA S.A. A joint-stock company (société anonyme) with a share capital of 524,771.88 euros Registered office: 50, rue de Dijon, 21121 Daix, France Dijon Trade and Companies Register 537 530 255 INTERIM FINANCIAL REPORT FOR THE SIX MONTHS ENDED JUNE 30, 2024 Table of Contents Table of contents 1. Interim Financial Report 3 1.1. General overview of activities 3 1.

October 15, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of October 2024 Commission File Number: 001-39

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of October 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive

October 15, 2024 EX-99.3

AMENDMENT No 4 TO THE EXCLUSIVE LICENSE AND COLLABORATION AGREEMENT

Exhibit 99.3 CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS EXHIBIT (INDICATED BY [***]) HAS BEEN OMITTED BECAUSE IT IS BOTH NOT MATERIAL AND IS THE TYPE THAT INVENTIVA S.A. TREATS AS PRIVATE OR CONFIDENTIAL. AMENDMENT No 4 TO THE EXCLUSIVE LICENSE AND COLLABORATION AGREEMENT This FOURTH AMENDMENT TO THE EXCLUSIVE LICENSE AND COLLABORATION AGREEMENT (this “Amendment #4”) is entered into as of

October 15, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of October 2024 Commission File Number: 001-39

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of October 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive

September 25, 2024 EX-99.1

Inventiva provides a corporate update and reports its unaudited 2024 first-half financial results

EXHIBIT 99.1 Inventiva provides a corporate update and reports its unaudited 2024 first-half financial results Recruitment in NATiV3 clinical trial progresses with over 85% of the targeted number of patients enrolled in the main cohort and a statistical powering of the study expected to be superior to 95% for both doses evaluated in the trial. Baseline characteristics of patients randomized in the

September 25, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September 2024 Commission File Number: 001-

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

July 31, 2024 EX-99.1

Inventiva Reports Preliminary 2024 First-Half Financial Information1

EXHIBIT 99.1 Inventiva Reports Preliminary 2024 First-Half Financial Information1 Cash and cash equivalents at €10.1 million as of June 30, 2024, compared to cash and cash equivalents at €26.9 million, €0.012 million of short-term deposits and €9.03 million of long-term deposits as of December 31, 2023. On July 18, 2024, Inventiva issued royalty certificates subscribed by Samsara BioCapital and ex

July 31, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2024 Commission File Number: 001-39374

6-K 1 f6k073124.htm FORM 6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Addr

July 19, 2024 SC 13D/A

IVA / Inventiva S.A. - Depositary Receipt (Common Stock) / BIOTECHNOLOGY VALUE FUND L P - AMENDMENT NO. 2 TO SCHEDULE 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 2)1 Inventiva S.A. (Name of Issuer) Ordinary Shares, nominal value €0.01 per share (Title of Class of Securities) 46124U107 (CUSIP Number) JAMES KRATKY BVF

July 18, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of July 2024 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of July 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive of

July 18, 2024 EX-99.1

Royalty Certificate Subscription Agreement

Exhibit 99.1 Royalty Certificate Subscription Agreement INVENTIVA 50, rue de Dijon 21121 Daix France The undersigned, [•] (the "Subscriber") hereby confirms its agreement with you as follows: 1. This Royalty Certificate Subscription Agreement (including the annexes attached hereto, the "Agreement" or the “Subscription Agreement”) is made as of the date set forth below between Inventiva S.A., a soc

July 18, 2024 EX-99.2

Inventiva announces a €20.1 million issuance of royalty certificates

Exhibit 99.2 Inventiva announces a €20.1 million issuance of royalty certificates ► Royalty certificates subscribed by Samsara BioCapital and existing shareholders (BVF Partners, NEA, Sofinnova and Yiheng). ► Royalty of 3% on future net sales of lanifibranor in the United States of America, the European Union and the United Kingdom over a 14-year term. ► Cash runway extended through September 2024

July 5, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2024 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

July 5, 2024 EX-99.1

Inventiva provides an update on its NATiV3 clinical program evaluating lanifibranor in patients with MASH/NASH and its financial position

EXHIBIT 99.1 Inventiva provides an update on its NATiV3 clinical program evaluating lanifibranor in patients with MASH/NASH and its financial position Recruitment in NATiV3 clinical trial continues in both cohorts with over 80% of the targeted number of patients enrolled in the main cohort and 100% in the exploratory cohort of NATiV3. Analysis of the baseline characteristics of all patients random

June 21, 2024 EX-99.1

Results of the votes of the Combined Shareholders’ General Meeting of June 20, 2024

EXHIBIT 99.1 Results of the votes of the Combined Shareholders’ General Meeting of June 20, 2024 Daix (France), Long Island City (New York, United States), on June 21, 2024 – Inventiva (Euronext Paris and Nasdaq: IVA) (the “Company”), a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of metabolic dysfunction-associated steatohe

June 21, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2024 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

June 21, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2024 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

June 21, 2024 EX-99.1

Description of the Share Repurchase Program Authorised by the Ordinary General Meeting of 20 June 2024

EXHIBIT 99.1 Description of the Share Repurchase Program Authorised by the Ordinary General Meeting of 20 June 2024 Daix, 21 June 2024 Pursuant to Article 241-2 of the AMF General Regulations (Règlement Général de l’Autorité des marchés financiers), the purpose of this description is to present the objectives and terms of the Company’s share repurchase program approved by the Ordinary General Meet

June 5, 2024 EX-99.1

INVENTIVA French société Anonyme with a Board of Directors with a share capital of EUR 524,771.88 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting

Exhibit 99.1 Translation for information purpose only INVENTIVA French société Anonyme with a Board of Directors with a share capital of EUR 524,771.88 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting The shareholders of INVENTIVA are informed that the Ordinary and Extraordinary General Meeting will be held on June 20, 2024 at 9 a.

June 5, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of June 2024 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of June 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive of

May 30, 2024 EX-99.1

Combined General Meeting of June 20, 2024 - Availability of the preparatory documents

EXHIBIT 99.1 Combined General Meeting of June 20, 2024 - Availability of the preparatory documents Daix (France), Long Island City (New York, United States), May 30, 2024 – Inventiva (Euronext Paris and Nasdaq: IVA), a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of metabolic dysfunction-associated steatohepatitis (“MASH”),

May 30, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and t

May 30, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and t

May 30, 2024 EX-99.1

Statement of total voting rights and shares forming the company’s share capital as of May 13, 2024 Article R. 22-10-23 of the French Commercial Code Market : Euronext Paris ISIN code / Mnemo : FR0013233012 / IVA Web site : www.inventivapharma.com Dat

EXHIBIT 99.1 Statement of total voting rights and shares forming the company’s share capital as of May 13, 2024 Article R. 22-10-23 of the French Commercial Code Market : Euronext Paris ISIN code / Mnemo : FR0013233012 / IVA Web site : www.inventivapharma.com Date Number of Shares Outstanding Total voting rights, gross (1) Total voting rights, net (2) May 13, 2024 52 477 188 65 493 081 65 381 630

May 21, 2024 EX-99.1

Inventiva reports 2024 First Quarter Financial Information1 and provides a corporate update

EXHIBIT 99.1 Inventiva reports 2024 First Quarter Financial Information1 and provides a corporate update Cash and cash equivalents at €11.0 million, short-term2 deposits at €0.1million, and long-term deposit at €19.1 million3 as of March 31, 2024, compared to €26.9 million, €0.01 million and €9.0 million as of December 31, 2023, respectively. The fourth scheduled DMC meeting recommended to continu

May 21, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and t

May 16, 2024 EX-99.1

Inventiva announces the positive recommendation of the fourth DMC of the NATiV3 Phase III clinical trial with lanifibranor in patients with MASH/NASH

EXHIBIT 99.1 Inventiva announces the positive recommendation of the fourth DMC of the NATiV3 Phase III clinical trial with lanifibranor in patients with MASH/NASH The Data Monitoring Committee recommended to continue the clinical trial without modification of the current protocol, based on the pre-planned review of safety data. The recommendation was based on the unblinded review by the DMC of saf

May 16, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and t

May 13, 2024 EX-99.1

Inventiva announces the publication in Nature Communications of additional results from NATIVE Phase IIb clinical trial demonstrating improvement of markers of cardiometabolic health in patients with MASH/NASH treated with lanifibranor

EXHIBIT 99.1 Inventiva announces the publication in Nature Communications of additional results from NATIVE Phase IIb clinical trial demonstrating improvement of markers of cardiometabolic health in patients with MASH/NASH treated with lanifibranor Improvements were observed for insulin resistance (insulin levels, HOMA-IR), lipid metabolism (triglycerides, HDL-cholesterol, apolipoproteins), contro

May 13, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of May 2024 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of May 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive off

May 13, 2024 EX-99.1

INVENTIVA Société Anonyme with a Board of Directors With a share capital of EUR 524,771.88 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting to the Ordinary and Extraordinary General M

Exhibit 99.1 Translation for information purpose only INVENTIVA Société Anonyme with a Board of Directors With a share capital of EUR 524,771.88 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting to the Ordinary and Extraordinary General Meeting dated June 20, 2024 The shareholders of INVENTIVA (the "Company") are informed that the O

May 13, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and t

May 3, 2024 SC 13D/A

IVA / Inventiva S.A. - Depositary Receipt (Common Stock) / New Enterprise Associates 17, L.P. - NEW ENTERPRISE ASSOCIATES 17, L.P. -- INVENTIVA S.A. 13D/A(#1) Activist Investment

SC 13D/A 1 nea17-inventiva18830.htm NEW ENTERPRISE ASSOCIATES 17, L.P. - INVENTIVA S.A. 13D/A(#1) UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 1)* Inventiva S.A. (Name of Issuer) Ordinary Shares, €.01 par value per share (Title of Class of Securities) 46124U107 (CUSIP Number) Stephanie Brecher New Ente

April 3, 2024 EX-4.8

EXCLUSIVE LICENSE AGREEMENT

Exhibit 4.8 CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS EXHIBIT (INDICATED BY [***]) HAS BEEN OMITTED BECAUSE IT IS BOTH NOT MATERIAL AND IS THE TYPE THAT INVENTIVA S.A. TREATS AS PRIVATE OR CONFIDENTIAL. EXCLUSIVE LICENSE AGREEMENT THIS EXCLUSIVE LICENSE AGREEMENT (the “Agreement”) is entered into as of September 20th, 2023 (the “Effective Date”), by and between INVENTIVA S.A., a company i

April 3, 2024 EX-4.1

Summary of BSA Plans

Exhibit 4.1 Summary of BSA Plans Share warrants (bons de souscription d’actions), or BSAs, entitle a holder to exercise the warrant for the underlying vested shares at an exercise price per share determined by our board of directors and at least equal to the fair market value of an ordinary share on the date of grant. In addition to any exercise price payable by a holder upon the exercise of any s

April 3, 2024 EX-13.1

Certification by the Principal Executive Officer and Principal Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

Exhibit 13.1 Certification by the Principal Executive Officer and Principal Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 Pursuant to the requirement set forth in Rule 13a-14(b) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), and Section 1350 of Chapter 63 of Title 18 of the United States Code (18

April 3, 2024 EX-4.3

Summary of Free Share Plans

Exhibit 4.3 Summary of Free Share Plans Free Shares (actions gratuites) are allotted for free to holders at an issuance price equal to the par value as set forth in the by-laws (€0.01). The issuance of the Free Shares will occur automatically at the end of the vesting period, by way of a capital increase, which will be realized by debiting the unavailable reserve (réserve non disponible) establish

April 3, 2024 EX-15.1

Consent of Independent Registered Public Accounting Firm

Exhibit 15.1 KPMG S.A. Tour Eqho 2 avenue Gambetta CS 60055 92066 Paris la Défense Cedex Telephone: +33 (0)1 55 68 68 68 Telefax: +33 (0)1 55 68 73 00 Internet: www.kpmg.fr Consent of Independent Registered Public Accounting Firm We consent to the incorporation by reference in the registration statement (No. 333-258369) on Form F-3 of our report dated April 2, 2024, with respect to the consolidate

April 3, 2024 EX-2.4

DESCRIPTION OF SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934

Exhibit 2.4 DESCRIPTION OF SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 The following description sets forth certain material terms and provisions of the securities of Inventiva S.A. (“Inventiva,” the “Company,” “we,” “us” and “our”) that are registered under Section 12 of the U.S. Securities Exchange Act of 1934, as amended (the “Exchange Act”). This descrip

April 3, 2024 EX-12.1

Certification by the Principal Executive Officer pursuant to Securities Exchange Act Rule 13a-14(a) or Rule 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Exhibit 12.1 Certification by the Principal Executive Officer pursuant to Securities Exchange Act Rule 13a-14(a) or Rule 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 I, Frédéric Cren, certify that: 1.I have reviewed this annual report on Form 20-F of Inventiva S.A.; 2.Based on my knowledge, this report does not contain any untrue statement of a material fact or om

April 3, 2024 EX-1.1

INVENTIVA Société anonyme à Conseil d’administration with a share capital of €521,158.07 Registered office: 50 Rue de Dijon, 21121, Daix, France Dijon Trade and Companies Register 537 530 255 ARTICLES OF ASSOCIATION UPDATED TO REFLECT THE CHIEF EXECU

Exhibit 1.1 INVENTIVA Société anonyme à Conseil d’administration with a share capital of €521,158.07 Registered office: 50 Rue de Dijon, 21121, Daix, France Dijon Trade and Companies Register 537 530 255 ARTICLES OF ASSOCIATION UPDATED TO REFLECT THE CHIEF EXECUTIVE OFFICER’S DECISIONS OF 8th December 2023 PART I FORM - NAME - OBJECTS - REGISTERED OFFICE - TERM ARTICLE 1. FORM The company (the “Co

April 3, 2024 EX-4.4

Performance Units (PAGUP)

Exhibit 4.4 Performance Units (PAGUP) On May 25, 2023, the Company's board of directors (the “Board”) granted 300,000 free performance units, or PAGUPs, to Mr. Frédéric Cren, the Chief Executive Officer and Chairman of the Board of the Company. The purpose of this plan is to provide Mr. Cren with a long-term incentive scheme under economically comparable conditions to those granted to Pierre Broqu

April 3, 2024 EX-4.9

SHAREHOLDERS AGREEMENT

Exhibit 4.9 Execution Version SHAREHOLDERS AGREEMENT Catalys Pacific Fund II, LP (“Catalys”), Inventiva S.A. (“Inventiva”) and Hepalys Pharma, Inc. (the “Company”) enter into this Shareholders Agreement (this “Agreement”) on September 20th, 2023 in respect of the Company on the terms and conditions set forth below. RECITALS (A) The parties entered into a Shareholders Agreement on May 11, 2023 (the

April 3, 2024 20-F

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 20-F

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 20-F (Mark One) ☐ REGISTRATION STATEMENT PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF

April 3, 2024 EX-4.2

Summary of BSPCE Plans

Exhibit 4.2 Summary of BSPCE Plans Founder’s share warrants (bons de souscription de parts de créateur d’entreprise), or BSPCEs, entitle a holder to exercise the warrant for the underlying vested shares at an exercise price per share determined by our Board of Directors and at least equal to the fair market value of an ordinary share on the date of grant. Because one of the conditions to be eligib

April 3, 2024 EX-12.2

Certification by the Principal Financial Officer pursuant to Securities Exchange Act Rule 13a-14(a) or Rule 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Exhibit 12.2 Certification by the Principal Financial Officer pursuant to Securities Exchange Act Rule 13a-14(a) or Rule 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 I, Jean Volatier, certify that: 1. I have reviewed this annual report on Form 20-F of Inventiva S.A.; 2.Based on my knowledge, this report does not contain any untrue statement of a material fact or o

April 3, 2024 EX-97

INVENTIVA S.A. INCENTIVE COMPENSATION RECOUPMENT POLICY

Exhibit 97 INVENTIVA S.A. INCENTIVE COMPENSATION RECOUPMENT POLICY 1.INTRODUCTION The Board of Directors (the “Board”) of Inventiva S.A. a société anonyme organized under the laws of France (the “Company”), has determined that it is in the best interests of the Company and its shareholders to adopt this Incentive Compensation Recoupment Policy (this “Policy”) providing for the Company’s recoupment

March 27, 2024 EX-99.1

Inventiva reports its 2023 full-year results

EXHIBIT 99.1 Inventiva reports its 2023 full-year results Revenues at €17.5 million for the full year of 2023 up 43.4% compared to €12.2 million for 2022 Cash and cash equivalents at €26.9 million, short-term deposits at €0.01 million1, and long-term deposit at €9.0 million2 as of December 31, 2023, compared to €86.7 million, €1.0 million, and €0.7 million respectively, as of December 31, 2022 In

March 27, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of March 2024 Commission File Number: 001-3937

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of March 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

March 18, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of March 2024 Commission File Number: 001-3937

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of March 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

March 18, 2024 EX-99.1

Inventiva announces positive results from the Phase II, LEGEND, Proof-of-Concept study combining lanifibranor with empagliflozin in patients with MASH/NASH and T2D

EdgarFiling EXHIBIT 99.1 Inventiva announces positive results from the Phase II, LEGEND, Proof-of-Concept study combining lanifibranor with empagliflozin in patients with MASH/NASH and T2D LEGEND achieved its primary efficacy endpoint by significantly lowering HbA1c level in both the lanifibranor arm and in the lanifibranor with empagliflozin arm compared to placebo. Statistical significance was a

March 7, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of March 2024 Commission File Number: 001-3937

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of March 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

March 7, 2024 EX-99.1

Inventiva announces that screening in the NATiV3, Phase III, clinical trial evaluating lanifibranor in NASH has resumed

EXHIBIT 99.1 Inventiva announces that screening in the NATiV3, Phase III, clinical trial evaluating lanifibranor in NASH has resumed Inventiva has lifted the voluntary pause on screening and randomization in the NATiV3 clinical trial following the approval from the US central IRB of the amended protocol and ICF. Screening of patients is resuming in sites operating under central IRB in the US. Othe

February 15, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of February 2024 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of February 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

February 15, 2024 EX-99.1

Inventiva reports preliminary 2023 fiscal year financial Informationˆ and provides an update on its clinical trial NATiV3

EXHIBIT 99.1 Inventiva reports preliminary 2023 fiscal year financial Informationˆ and provides an update on its clinical trial NATiV3 Revenues of €17.5 million for the full year of 2023, compared to €12.2 million for 2022 Cash and cash equivalents at €26.9 million, short-term deposits at € 0.01 million2, and long-term deposit at €9.0 million3 as of December 31, 2023, compared to €86.7 million, €1

February 14, 2024 SC 13G/A

US46124U1079 / INVENTIVA SA-ADR / Yiheng Capital Management, L.P. - YIHENGIVA13GA1 Passive Investment

SC 13G/A 1 yihengiva13ga1.htm YIHENGIVA13GA1 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.1)* Inventiva S.A. (Name of Issuer) Ordinary shares, par value $0.01 per share (Title of Class of Securities) 46124U107 (CUSIP Number) Yiheng Capital Management, L.P. 101 California Street, Suite 2880 San Francisco

February 9, 2024 SC 13G/A

US46124U1079 / INVENTIVA SA-ADR / Sofinnova Crossover I - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2 (Amendment No. 3) * Inventiva S.A. (Name of Issuer) Ordinary Shares, nominal value €0.01 per share (Title of Class of Securities) 46124U107 (CUSIP Number) Decem

February 9, 2024 EX-99.1

US46124U1079 / INVENTIVA SA-ADR / Sofinnova Crossover I - EXHIBIT 1 Joint Filing Agreement

EX-99.1 2 tm245335d1ex-1.htm EXHIBIT 1 Exhibit 1 Joint Filing Agreement In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the undersigned agree to the joint filing on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the ordinary shares of Inventiva S.A. and further agree that this agreement be included as an

January 10, 2024 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of January 2024 Commission File Number: 001-39

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of January 2024 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, a

January 10, 2024 EX-99.1

Inventiva draws down the second tranche of €25 million under existing Finance Contract with the European Investment Bank

EXHIBIT 99.1 Inventiva draws down the second tranche of €25 million under existing Finance Contract with the European Investment Bank Inventiva intends to use the proceeds to fund part of its ongoing pivotal NATiV3 Phase III clinical trial evaluating lanifibranor in patients with NASH. This second tranche carries an interest rate of 7% annually and has a maturity of 3 years and a repayment in fine

December 20, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of December 2023 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of December 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

December 20, 2023 EX-99.1

Inventiva announces the randomization of the first patient in China in the NATiV3 clinical trial and provides an update on its clinical development program

EXHIBIT 99.1 Inventiva announces the randomization of the first patient in China in the NATiV3 clinical trial and provides an update on its clinical development program The first patient was randomized in China in the NATiV3 Phase III clinical trial, triggering a milestone payment of $3 million from CTTQ to Inventiva. With this milestone payment Inventiva expects to have met the operational and fi

November 21, 2023 EX-99.1

Inventiva reports 2023 Third Quarter Financial Information1

EXHIBIT 99.1 Inventiva reports 2023 Third Quarter Financial Information1 Cash and cash equivalents at €43.8 million, short-term deposits at €0.03 million2, and long-term deposit at €5.0 million3 as of September 30, 2023, compared to €86.7 million, €1.0 million and €0.7 million as of December 31, 2022, respectively Revenues of €1.9 million for the first nine months of 2023, compared to €0.1 million

November 21, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2023 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

October 3, 2023 EX-99.1

INVENTIVA S.A. A joint-stock company (société anonyme) with a share capital of 517,528.07 euros Registered office: 50, rue de Dijon, 21121 Daix, France Dijon Trade and Companies Register 537 530 255 INTERIM FINANCIAL REPORT FOR THE SIX MONTHS ENDED J

Table of Contents Exhibit 99.1 INVENTIVA S.A. A joint-stock company (société anonyme) with a share capital of 517,528.07 euros Registered office: 50, rue de Dijon, 21121 Daix, France Dijon Trade and Companies Register 537 530 255 INTERIM FINANCIAL REPORT FOR THE SIX MONTHS ENDED JUNE 30, 2023 Table of Contents Table of contents 1. Interim Financial Report 3 1.1. General overview of activities 3 1.

October 3, 2023 6-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K/A (Amendment No. 1) REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September, 2023 Commiss

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K/A (Amendment No. 1) REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September, 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address

September 29, 2023 EX-1.1

SALES AGREEMENT

Exhibit 1.1 Execution Version SALES AGREEMENT September 28, 2023 Cowen and Company, LLC 599 Lexington Avenue New York, NY 10022 Ladies and Gentlemen: Inventiva S.A., a société anonyme organized under the laws of France and registered with the Register of Commerce and Companies (Registre du Commerce et des Sociétés) of Dijon under number 537 530 255 (the “Company”), proposes, subject to the terms a

September 29, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of September 2023 Commission File Number: 001-

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of September 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executi

September 28, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September, 2023 Commission File Number: 001

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September, 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal execut

September 28, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September 2023 Commission File Number: 001-

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

September 28, 2023 EX-99.1

INVENTIVA S.A. A joint-stock company (société anonyme) with a share capital of 517,528.07 euros Registered office: 50, rue de Dijon, 21121 Daix, France Dijon Trade and Companies Register 537 530 255 INTERIM FINANCIAL REPORT FOR THE SIX MONTHS ENDED J

Table of Contents Exhibit 99.1 INVENTIVA S.A. A joint-stock company (société anonyme) with a share capital of 517,528.07 euros Registered office: 50, rue de Dijon, 21121 Daix, France Dijon Trade and Companies Register 537 530 255 INTERIM FINANCIAL REPORT FOR THE SIX MONTHS ENDED JUNE 30, 2023 Table of Contents Table of contents 1. Interim Financial Report 3 1.1. General overview of activities 3 1.

September 28, 2023 EX-99.1

Inventiva reports its 2023 first-half financial results and provides a corporate update

EXHIBIT 99.1 Inventiva reports its 2023 first-half financial results and provides a corporate update Cash and cash equivalents at €31.2 million, short-term deposits at €0.05 million1, and long-term deposit at €9.3 million2, as of June 30, 2023, compared to €86.7 million, €1.0 million and €0.7 million as of December 31, 2022, respectivel Revenues amounted to €1.9 million for the first half of 2023

September 28, 2023 424B5

Up to $58,000,000 American Depositary Shares representing Ordinary Shares

TABLE OF CONTENTS   Filed pursuant to Rule 424(b)(5)  Registration No. 333-258369 PROSPECTUS SUPPLEMENT (To Prospectus Dated August 6, 2021) Up to $58,000,000 American Depositary Shares representing Ordinary Shares We have entered into a sale agreement, or Sales Agreement, with Cowen and Company, LLC, or TD Cowen, relating to the sale of American Depositary Shares, or ADSs, each ADS representing o

September 25, 2023 SC 13D/A

US46124U1079 / INVENTIVA SA-ADR / BIOTECHNOLOGY VALUE FUND L P - AMENDMENT NO. 1 TO SCHEDULE 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 1)1 Inventiva S.A. (Name of Issuer) Ordinary Shares, nominal value €0.01 per share (Title of Class of Securities) 46124U107 (CUSIP Number) JAMES KRATKY BVF

September 20, 2023 EX-99.1

Inventiva and Hepalys Pharma, Inc. announce exclusive licensing agreement to develop and commercialize lanifibranor in Japan and South Korea

EdgarFiling EXHIBIT 99.1 Inventiva and Hepalys Pharma, Inc. announce exclusive licensing agreement to develop and commercialize lanifibranor in Japan and South Korea Hepalys Pharma, Inc. is a new company created by Catalys Pacific and in which Inventiva has a 30% ownership position. Under the exclusive licensing agreement, Inventiva will receive a $10 million upfront payment, and is eligible to re

September 20, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September 2023 Commission File Number: 001-

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

September 5, 2023 SC 13G

US46124U1079 / INVENTIVA SA-ADR / Qatar Investment Authority - SCHEDULE FILED TO REPORT ACQUISITION OF BENEFICIAL OWNERSHIP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Inventiva S.A. (Name of Issuer) Ordinary shares, par value €0.01 per share (Title of Class of Securities) 46124U107 (CUSIP Number) August 30, 2023 (Date of Event Which Requires Filing this Statement) Check the appropriate box to designate the rule pursuan

August 31, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of August 2023 Commission File Number: 001-393

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of August 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive

August 31, 2023 EX-99.2

Royalty Certificate Subscription Agreement

Exhibit 99.2 Royalty Certificate Subscription Agreement INVENTIVA 50, rue de Dijon 21121 Daix France The undersigned, [•] (the “Subscriber”) hereby confirms its agreement with you as follows: 1. This Royalty Certificate Subscription Agreement (including the annexes attached hereto, the “Agreement”) is made as of the date set forth below between Inventiva S.A., a société anonyme organized under the

August 31, 2023 EX-99.1

Subscription Agreement

Exhibit 99.1 Subscription Agreement INVENTIVA 50, rue de Dijon 21121 Daix France The undersigned, [•] (the “Subscriber”) hereby confirms its agreement with you as follows: 1. This Subscription Agreement (including the annexes attached hereto, the “Agreement”) is made as of the date set forth below between Inventiva S.A., a société anonyme organized under the laws of the French Republic, with a sha

August 31, 2023 EX-99.3

Inventiva announces a financing of approximately €35.7 million from new and existing investors, consisting of a €30.6 million reserved capital increase and a €5.1 million issuance of royalty certificates

Exhibit 99.3 PRESS RELEASE Inventiva announces a financing of approximately €35.7 million from new and existing investors, consisting of a €30.6 million reserved capital increase and a €5.1 million issuance of royalty certificates Daix (France), Long Island City (New York, United States), August 31, 2023 – Inventiva (Euronext Paris and Nasdaq: IVA) (the “Company”), a clinical-stage biopharmaceutic

July 27, 2023 EX-99.1

Inventiva Reports Preliminary 2023 First-Half Financial Information1 and Business update

EXHIBIT 99.1 Inventiva Reports Preliminary 2023 First-Half Financial Information1 and Business update Cash and cash equivalents at €31.2 million, short-term deposits at €0.05 million2, and long-term deposit at €9.3 million3 as of June 30, 2023, compared to €86.7 million, €1.0 million and €0.7 million as of December 31, 2022, respectively Revenues of €1.9 m in H1 2023, compared to €0.1 million for

July 27, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2023 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

June 14, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2023 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

June 14, 2023 EX-99.1

Inventiva announces positive topline results from the investigator-initiated Phase II clinical trial evaluating lanifibranor in patients with T2D and NAFLD

EXHIBIT 99.1 Inventiva announces positive topline results from the investigator-initiated Phase II clinical trial evaluating lanifibranor in patients with T2D and NAFLD Lanifibranor 800mg achieved the primary efficacy endpoint demonstrating a 44% reduction of hepatic fat measured by proton magnetic resonance spectroscopy (1H-MRS) following 24 weeks of treatment in patients with nonalcoholic fatty

May 26, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2023 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and t

May 26, 2023 EX-99.1

Results of the votes of the Combined Shareholders’ General Meeting of May 25, 2023

EdgarFiling EXHIBIT 99.1 Results of the votes of the Combined Shareholders’ General Meeting of May 25, 2023 Daix (France), Long Island City (New York, United States), May 26, 2023 – Inventiva (Euronext Paris and Nasdaq: IVA), a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of non-alcoholic steatohepatitis (NASH) and other dis

May 25, 2023 EX-99.1

Description of the Share Repurchase Program Authorised by the Ordinary General Meeting of 25 May 2023

EdgarFiling EXHIBIT 99.1 Description of the Share Repurchase Program Authorised by the Ordinary General Meeting of 25 May 2023 Daix, 25 May 2023 Pursuant to Article 241-2 of the AMF General Regulations (Règlement Général de l’Autorité des marchés financiers), the purpose of this description is to present the objectives and terms of the Company’s share repurchase program approved by the Ordinary Ge

May 25, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2023 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and t

May 25, 2023 EX-99.1

Inventiva announces that its partner Sino Biopharm received IND approval from the NMPA to initiate clinical trial with lanifibranor in China

EdgarFiling EXHIBIT 99.1 Inventiva announces that its partner Sino Biopharm received IND approval from the NMPA to initiate clinical trial with lanifibranor in China Chia Tai Tianqing Pharmaceutical Group Co., Ltd., a Sino Biopharm’s subsidiary, receives IND approval from the NMPA to initiate the clinical development in mainland China of lanifibranor in NASH Sino Biopharm will participate in the o

May 25, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2023 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and t

May 16, 2023 EX-99.1

Inventiva reports 2023 First Quarter Financial Information1 and provides a corporate update

EXHIBIT 99.1 Inventiva reports 2023 First Quarter Financial Information1 and provides a corporate update Cash and cash equivalents at €56.3 million, short-term deposits at €0.7 million2, and long term deposit at €9.3 million3 as of March 31, 2023, compared to €86.7 million, €1.0 million and €0.7 million as of December 31, 2022, respectively Improvements on NATiV3 Phase III clinical trial with lani

May 16, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2023 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and t

May 5, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of May 2023 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of May 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive off

May 5, 2023 EX-99.1

French société Anonyme with a Board of Directors with a share capital of EUR 421,341.69 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting

Exhibit 99.1 Translation for information purpose only INVENTIVA French société Anonyme with a Board of Directors with a share capital of EUR 421,341.69 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting The shareholders of INVENTIVA are informed that the Ordinary and Extraordinary General Meeting will be held on May 25, 2023 at 2 p.m

May 4, 2023 EX-99.2

Statement of total voting rights and shares forming the company’s share capital as of April 17, 2023 Article R. 22-10-23 of the French Commercial Code Market : Euronext Paris ISIN code / Mnemo : FR0013233012 / IVA Web site : www.inventivapharma.com D

EdgarFiling EXHIBIT 99.2 Statement of total voting rights and shares forming the company’s share capital as of April 17, 2023 Article R. 22-10-23 of the French Commercial Code Market : Euronext Paris ISIN code / Mnemo : FR0013233012 / IVA Web site : www.inventivapharma.com Date Number of Shares Outstanding Total voting rights, gross (1) Total voting rights, net (2) 17 April 2023 42 134 169 55 141

May 4, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2023 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and t

May 4, 2023 EX-99.1

Combined General Meeting of May 25, 2023. Availability of the preparatory documents

EdgarFiling EXHIBIT 99.1 Combined General Meeting of May 25, 2023. Availability of the preparatory documents Daix (France), Long Island City (New York, United States), May 4, 2023 – Inventiva (Euronext Paris and Nasdaq: IVA), a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of patients with non-alcoholic steatohepatitis (NASH)

April 25, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of April 2023 Commission File Number: 001-3937

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of April 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive o

April 25, 2023 EX-99.1

23201 Inventiva SA VIF Proof 3 PROXY TABULATOR FOR INVENTIVA S.A. P.O. BOX 8016 CARY, NC 27512-9903 Inventiva S.A. Instructions to The Bank of New York Mellon, as Depositary (Must be received prior to 12:00 PM Eastern Time May 19, 2023) The undersign

Exhibit 99.1 23201 Inventiva SA VIF Proof 3 Ordinary and Extraordinary General Meeting of Inventiva S.A. Date: May 25, 2023 See Voting Instruction On Reverse Side. Please make your marks like this: x Use pen only Ordinary and Extraordinary General Meeting of Inventiva S.A. to be held May 25, 2023 For Holders as of April 17, 2023 All votes must be received by 12:00 PM Eastern Time May 19, 2023. OGM

April 25, 2023 EX-99.2

INVENTIVA S.A. Ordinary and Extraordinary General Meeting of Inventiva S.A. to be held on May 25, 2023 Instructions for beneficial owners of American Depositary Shares (“ADSs” )

Exhibit 99.2 INVENTIVA S.A. Ordinary and Extraordinary General Meeting of Inventiva S.A. to be held on May 25, 2023 Instructions for beneficial owners of American Depositary Shares (“ADSs” ) Beneficial owners of ADSs who wish to submit their votes in connection with the General Meeting of Inventiva to be held on May 25, 2023 should consult the voting instruction form delivered to them by The Bank

April 17, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of April 2023 Commission File Number: 001-3937

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of April 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive o

April 17, 2023 EX-99.1

INVENTIVA Société Anonyme with a Board of Directors With a share capital of EUR 421,341.69 Registered Office : 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting to the Ordinary and Extraordinary General

Exhibit 99.1 Translation for information purpose only INVENTIVA Société Anonyme with a Board of Directors With a share capital of EUR 421,341.69 Registered Office : 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting to the Ordinary and Extraordinary General Meeting dated May 25, 2023 The shareholders of INVENTIVA (the "Company") are informed that the O

March 30, 2023 EX-4.1

Summary of BSA 2017, BSA 2018 and BSA 2019, BSA 2019 bis, BSA 2019 ter, and BSA 2021 Plans

Exhibit 4.1 Summary of BSA Plans Share warrants (bons de souscription d’actions), or BSAs, entitle a holder to exercise the warrant for the underlying vested shares at an exercise price per share determined by our board of directors and at least equal to the fair market value of an ordinary share on the date of grant. In addition to any exercise price payable by a holder upon the exercise of any s

March 30, 2023 EX-4.2

Summary of BSPCE 2013-1 and BSPCE 2021 Plans

Exhibit 4.2 Summary of BSPCE Plans Founder’s share warrants (bons de souscription de parts de créateur d’entreprise), or BSPCEs, entitle a holder to exercise the warrant for the underlying vested shares at an exercise price per share determined by our board of directors and at least equal to the fair market value of an ordinary share on the date of grant. Founder’s share warrants may only be issue

March 30, 2023 EX-4.3

Summary of AGA 2021-1, AGA 2021 bis and AGA 2022 Free Share Plans (English Translation)

EX-4.3 6 iva-20221231xex4d3.htm EXHIBIT 4.3 Exhibit 4.3 Summary of Free Share Plans Free Shares (actions gratuites) are allotted for free to holders at an issuance price equal to the par value as set forth in the by-laws (€0.01). The issuance of the Free Shares will occur automatically at the end of the vesting period, by way of a capital increase, which will be realized by debiting the unavailabl

March 30, 2023 EX-2.4

Description of Securities

Exhibit 2.4 DESCRIPTION OF SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 The following description sets forth certain material terms and provisions of the securities of Inventiva S.A. (“Inventiva,” the “Company,” “we,” “us” and “our”) that are registered under Section 12 of the U.S. Securities Exchange Act of 1934, as amended (the “Exchange Act”). This descrip

March 30, 2023 EX-13.2

Certification by the Principal Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

Exhibit 13.2 CERTIFICATION OF CFO PURSUANT TO 18 U.S.C. SECTION 1350 AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002 Pursuant to the requirement set forth in Rule 13a-14(b) of the Securities Exchange Act of 1934, as amended, (the “Exchange Act”) and Section 1350 of Chapter 63 of Title 18 of the United States Code (18 U.S.C. §1350), Jean Volatier, Chief Financial Officer of Inv

March 30, 2023 20-F

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 20-F

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 20-F (Mark One) ☐ REGISTRATION STATEMENT PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF

March 30, 2023 EX-12.2

Certification by the Principal Financial Officer pursuant to Securities Exchange Act Rules 13a-14(a) and 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Exhibit 12.2 Certification by the Principal Financial Officer pursuant to Securities Exchange Act Rules 13a-14(a) and 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 I, Jean Volatier, certify that: 1. I have reviewed this annual report on Form 20-F of Inventiva S.A. (the “Company”); 2. Based on my knowledge, this report does not contain any untrue statement of a mate

March 30, 2023 EX-12.1

Certification by the Principal Executive Officer pursuant to Securities Exchange Act Rules 13a-14(a) and 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Exhibit 12.1 Certification by the Principal Executive Officer pursuant to Securities Exchange Act Rules 13a-14(a) and 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 I, Frédéric Cren, certify that: 1. I have reviewed this annual report on Form 20-F of Inventiva S.A. (the “Company”); 2. Based on my knowledge, this report does not contain any untrue statement of a mate

March 30, 2023 EX-15.1

Consent of KPMG S.A.

Exhibit 15.1 KPMG S.A. Téléphone : +33 (0)1 55 68 68 68 Tour EQHO Télécopie : +33 (0)1 55 68 73 00 2 Avenue Gambetta Site internet : www.kpmg.fr CS 60055 92066 Paris la Défense Cedex France Consent of Independent Registered Public Accounting Firm We consent to the incorporation by reference in the registration statement (No. 333-258369) on Form F-3 of our report dated March 27, 2023, with respect

March 30, 2023 EX-1.1

Bylaws of the registrant (English translation).

Exhibit 1.1 INVENTIVA Société anonyme à Conseil d’administration with a share capital of €421,341.69 Registered office: 50 Rue de Dijon, 21121, Daix, France Dijon Trade and Companies Register 537 530 255 ARTICLES OF ASSOCIATION UPDATED TO REFLECT THE CHIEF EXECUTIVE OFFICER’S DECISIONS OF 6th July 2022 PART I FORM - NAME - OBJECTS - REGISTERED OFFICE - TERM ARTICLE 1.FORM The company (the “Company

March 30, 2023 EX-13.1

Certification by the Principal Executive Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

Exhibit 13.1 CERTIFICATION OF CEO PURSUANT TO 18 U.S.C. SECTION 1350 AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002 Pursuant to the requirement set forth in Rule 13a-14(b) of the Securities Exchange Act of 1934, as amended, (the “Exchange Act”) and Section 1350 of Chapter 63 of Title 18 of the United States Code (18 U.S.C. §1350), Frédéric Cren, Chief Executive Officer of Inv

March 29, 2023 EX-99.1

Inventiva reports its 2022 full-year results

EdgarFiling EXHIBIT 99.1 Inventiva reports its 2022 full-year results Cash and cash equivalents at €86.7 million and short term deposits at €1 million as of December 31, 2022 compared to €86.6 million and €8.8 million, respectively as of December 31, 2021 Inventiva entered into a license and collaboration agreement with Sino Biopharm a leading Chinese pharmaceutical group, through CTTQ, to develop

March 29, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of March 2023 Commission File Number: 001-3937

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of March 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

February 14, 2023 SC 13G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.__)* Inventiva S.A. (Name of Issuer) Ordinary shares, par value $0.01 per share (Title of Class of Securities

SC 13G 1 yiheng13gIVA.htm YIHENG13GIVA UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.)* Inventiva S.A. (Name of Issuer) Ordinary shares, par value $0.01 per share (Title of Class of Securities) 46124U107 (CUSIP Number) Yiheng Capital Management, L.P. 101 California Street, Suite 2880 San Francisco, CA 94

February 14, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of February 2023 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of February 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

February 14, 2023 EX-99.1

Inventiva reports preliminary financial results for Full-Year 20221

EXHIBIT 99.1 Inventiva reports preliminary financial results for Full-Year 20221 Daix (France), Long Island City (New York, United States), February 14, 2023 – Inventiva (Euronext Paris and Nasdaq: IVA) (the “Company”), a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of patients with non-alcoholic steatohepatitis (“NASH”) and

February 13, 2023 SC 13G/A

US46124U1079 / INVENTIVA SA-ADR / Sofinnova Crossover I - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2 (Amendment No. 2) * Inventiva S.A. (Name of Issuer) Ordinary Shares, nominal value €0.01 per share (Title of Class of Securities) 46124U107 (CUSIP Number) Decem

February 13, 2023 EX-99.1

Joint Filing Agreement

EX-99.1 2 tm236518d1ex99-1.htm EXHIBIT 99.1 CUSIP NO. 46124U107 Page 15 of 15 Pages Joint Filing Agreement In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the undersigned agree to the joint filing on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the ordinary shares of Inventiva S.A. and further agree tha

January 26, 2023 EX-99.1

Results of the votes of the Combined Shareholders’ General Meeting of January 25, 2023

EdgarFiling EXHIBIT 99.1 Results of the votes of the Combined Shareholders’ General Meeting of January 25, 2023 Daix (France), Long Island City (New York, United States), January 26, 2023 – Inventiva (Euronext Paris and Nasdaq: IVA), a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of non-alcoholic steatohepatitis (NASH) and o

January 26, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of January 2023 Commission File Number: 001-39

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of January 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, a

January 6, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of January 2023 Commission File Number: 001-39

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of January 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive

January 6, 2023 EX-99.1

INVENTIVA Société Anonyme with a Board of Directors With a share capital of EUR 421,341.69 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting

Exhibit 99.1 Translation for information purpose only INVENTIVA Soci?t? Anonyme with a Board of Directors With a share capital of EUR 421,341.69 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting The shareholders of INVENTIVA are informed that the Ordinary and Extraordinary General Meeting will be held on January 25, 2023 at 2 p.m.,

January 4, 2023 EX-99.1

Inventiva announces changes to the clinical development of lanifibranor, including plans for a new Phase III trial in patients with NASH and compensated cirrhosis

EXHIBIT 99.1 Inventiva announces changes to the clinical development of lanifibranor, including plans for a new Phase III trial in patients with NASH and compensated cirrhosis Proposed changes are expected to be beneficial to the lanifibranor clinical program by reducing the number of biopsies and the trial duration, eventually offering all patients in the trial access to treatment and potentially

January 4, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of January 2023 Commission File Number: 001-39

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of January 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, a

January 3, 2023 EX-99.1

Please separate carefully at the perforation and return just this portion in the envelope provided. Ordinary and Extraordinary General Meeting of Inventiva S.A. Ordinar y an d Extraordinar y Genera l Meetin g o f Inventiv a S.A. to be held January 25

Exhibit 99.1 Please separate carefully at the perforation and return just this portion in the envelope provided. Ordinary and Extraordinary General Meeting of Inventiva S.A. Ordinar y an d Extraordinar y Genera l Meetin g o f Inventiv a S.A. to be held January 25, 2023 Date: January 25, 2023 See Voting Instruction On Reverse Side. Please make your marks like this: Use pen only For Holders as of De

January 3, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 January 3, 2023 Commission File Number: 001-39374 Inventiva

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 January 3, 2023 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant?s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive office) Indic

January 3, 2023 EX-99.3

Combined General Meeting of January 25, 2023 Availability of the preparatory documents

EX-99.3 4 tm2233812d1ex99-3.htm EXHIBIT 99.3 Exhibit 99.3 PRESS RELEASE Combined General Meeting of January 25, 2023 Availability of the preparatory documents Daix (France), Long Island City (New York, United States), January 3, 2023 – Inventiva (Euronext Paris and Nasdaq: IVA), a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment

January 3, 2023 EX-99.4

Statement of total voting rights and shares forming the company’s share capital as of December 19, 2022 Article R. 22-10-23 of the French Commercial Code Market : Euronext Paris ISIN code / Mnemo : FR0013233012 / IVA Web site : www.inventivapharma.co

Exhibit 99.4 PRESS RELEASE Statement of total voting rights and shares forming the company?s share capital as of December 19, 2022 Article R. 22-10-23 of the French Commercial Code Market : Euronext Paris ISIN code / Mnemo : FR0013233012 / IVA Web site : www.inventivapharma.com Date Number of Shares Outstanding Total voting rights, gross (1) Total voting rights, net (2) December 19, 2022 42 134 16

January 3, 2023 EX-99.2

INVENTIVA S.A. Ordinary and Extraordinary General Meeting of Inventiva S.A. to be held on January 25, 2023 Instructions for beneficial owners of American Depositary Shares (“ADSs” )

EX-99.2 3 tm2233812d1ex99-2.htm EXHIBIT 99.2 Exhibit 99.2 INVENTIVA S.A. Ordinary and Extraordinary General Meeting of Inventiva S.A. to be held on January 25, 2023 Instructions for beneficial owners of American Depositary Shares (“ADSs” ) Beneficial owners of ADSs who wish to submit their votes in connection with the General Meeting of Inventiva to be held on January 25, 2023 should consult the v

December 19, 2022 EX-99.1

INVENTIVA Société Anonyme with a Board of Directors With a share capital of EUR 421,341.69 Registered Office : 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting to the Ordinary and Extraordinary General

Exhibit 99.1 Translation for information purpose only INVENTIVA Société Anonyme with a Board of Directors With a share capital of EUR 421,341.69 Registered Office : 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting to the Ordinary and Extraordinary General Meeting dated January 25, 2023 The shareholders of INVENTIVA are informed that the Ordinary and

December 19, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of December 2022 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of December 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executiv

December 12, 2022 EX-99.1

Inventiva draws down €25 million tranche under Finance Contract with the European Investment Bank

EdgarFiling EXHIBIT 99.1 Inventiva draws down €25 million tranche under Finance Contract with the European Investment Bank Inventiva intends to use the proceeds to fund part of the pivotal Phase III clinical trial evaluating lanifibranor in patients with NASH The €25 million supports Inventiva’s anticipated cash runway1 through the fourth quarter of 2023 Daix (France), Long Island City (New York,

December 12, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of December 2022 Commission File Number: 001-3

6-K 1 f6k121222.htm FORM 6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of December 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (

November 21, 2022 EX-99.1

Inventiva announces a new Director of the Board of Directors

EXHIBIT 99.1 Inventiva announces a new Director of the Board of Directors Daix (France), Long Island City (New York, United States), November 21, 2022 ? Inventiva (Euronext Paris and Nasdaq: IVA), a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of nonalcoholic steatohepatitis (NASH) and other diseases with significant unmet m

November 21, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2022 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

November 10, 2022 EX-99.1

Inventiva reports 2022 Third Quarter Financial Informationˆ

EXHIBIT 99.1 Inventiva reports 2022 Third Quarter Financial Information? Cash position2 at ?72.6m as of September 30, 2022, not including the $12.6 million upfront payment received from Sino Biopharm on November 4, 2022 Revenues of ?0.1m for the first nine months of 2022 Daix (France), Long Island City (New York, United States), November 10, 2022 ? Inventiva (Euronext Paris and Nasdaq: IVA) (the ?

November 10, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2022 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

October 31, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of October 2022 Commission File Number: 001-39

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of October 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, a

October 31, 2022 EX-99.1

Inventiva provides an update on the development of cedirogant by AbbVie

Exhibit 99.1 PRESS RELEASE Inventiva provides an update on the development of cedirogant by AbbVie Daix (France), Long Island City (New York, United States), October 31, 2022 – Inventiva (Euronext Paris and Nasdaq: IVA), a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of non-alcoholic steatohepatitis (NASH), mucopolysaccharid

September 27, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of September 2022 Commission File Number: 001-

6-K 1 tm2226712d16k.htm FORM 6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of September 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant’s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75

September 27, 2022 EX-99.1

EXCLUSIVE LICENSE AND COLLABORATION AGREEMENT

Exhibit 99.1 CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS EXHIBIT (INDICATED BY [***]) HAS BEEN OMITTED PURSUANT TO ITEM 601(B)(10) OF REGULATION S-K BECAUSE IT IS BOTH NOT MATERIAL AND IS THE TYPE THAT INVENTIVA S.A. TREATS AS PRIVATE OR CONFIDENTIAL. EXCLUSIVE LICENSE AND COLLABORATION AGREEMENT This Exclusive License and Collaboration Agreement (the ?Agreement?) is entered into as of Sept

September 22, 2022 EX-99.1

Inventiva and Sino Biopharm announce licensing and collaboration agreement to develop and commercialize lanifibranor in Greater China

Exhibit 99.1 Inventiva and Sino Biopharm announce licensing and collaboration agreement to develop and commercialize lanifibranor in Greater China ? Sino Biopharm a leading Chinese pharmaceutical group, through CTTQ will oversee the development and commercialization of lanifibranor in Greater China ? Lanifibranor is an orally-available small molecule with breakthrough therapy designation from the

September 22, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September 2022 Commission File Number: 001-

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code,

September 22, 2022 EX-99.3

Inventiva reports its 2022 first-half financial results and provides a corporate update

Exhibit 99.3 PRESS RELEASE Inventiva reports its 2022 first-half financial results and provides a corporate update ? Cash position1 at ?87.2 million as of June 30, 2022, compared to ?95.4 million as of December 31, 2021 ? Receipt of a ?4 million milestone payment from Inventiva?s partner AbbVie for cedirogant Phase IIb clinical trial initiation accounted for in 2021 revenues and H1 2022 cash flow

September 22, 2022 EX-99.2

INVENTIVA S.A. A joint-stock company (société anonyme) with a share capital of 421,341.69 euros Registered office: 50, rue de Dijon, 21121 Daix, France Dijon Trade and Companies Register 537 530 255 INTERIM FINANCIAL REPORT FOR THE SIX MONTHS ENDED J

Exhibit 99.2 INVENTIVA S.A. A joint-stock company (soci?t? anonyme) with a share capital of 421,341.69 euros Registered office: 50, rue de Dijon, 21121 Daix, France Dijon Trade and Companies Register 537 530 255 INTERIM FINANCIAL REPORT FOR THE SIX MONTHS ENDED JUNE 30, 2022 Table of contents 1. ?????Interim Financial Report 2 1.1. General overview of activities 2 1.2. Significant events in first-

July 28, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2022 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

July 28, 2022 EX-99.1

Inventiva Reports 2022 First-Half Financial Informationˆ

EXHIBIT 99.1 Inventiva Reports 2022 First-Half Financial Information? Cash position2 at ?87.2 m as of June 30, 2022 Revenues of ?0.1 m in H1 2022 Inventiva entered into a finance loan and a warrant agreement for up to ?50 million with the European Investment Bank (EIB) Inventiva raised approximately ?14.6m through a combination of its At-The-Market program (for ?9.3m in gross proceeds) and new Sta

July 5, 2022 EX-99.1

Update on Inventiva's cash position and on the finance documentation with the European Investment Bank

Exhibit 99.1 PRESS RELEASE Update on Inventiva's cash position and on the finance documentation with the European Investment Bank ? Inventiva successfully raised approximately ?14.6 million through a combination of its ATM Program for ?9.3 million and new State-backed bank financing for ?5.3 million ? In accordance with the terms of the credit facility announced on May 16, 2022, Inventiva entered

July 5, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2022 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

June 1, 2022 6-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K/A REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2022 Commission File Number: 001-3937

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K/A REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and

May 20, 2022 EX-99.1

Results of the votes of the Combined Shareholders’ Meeting of May 19, 2022

Exhibit 99.1 PRESS RELEASE Results of the votes of the Combined Shareholders? Meeting of May 19, 2022 Daix (France), Long Island City (New York, United States), May 20, 2022 ? Inventiva (Euronext Paris and Nasdaq: IVA), a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of non-alcoholic steatohepatitis (NASH) and other diseases

May 20, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2022 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and t

May 19, 2022 EX-99.1

DESCRIPTION OF THE SHARE REPURCHASE PROGRAM AUTHORISED BY THE ORDINARY GENERAL MEETING OF 19 MAY 2022

Exhibit 99.1 PRESS RELEASE DESCRIPTION OF THE SHARE REPURCHASE PROGRAM AUTHORISED BY THE ORDINARY GENERAL MEETING OF 19 MAY 2022 Daix, May 19, 2022 Pursuant to Article 241-2 of the AMF General Regulations (R?glement G?n?ral de l?Autorit? des march?s financiers), the purpose of this description is to present the objectives and terms of the share repurchase program of Inventiva S.A. (the ?Company?)

May 19, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2022 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and t

May 16, 2022 EX-99.2

INVENTIVA (EGFF) Finance Contract between the European Investment Bank Inventiva S.A. 16 May 2022

Exhibit 99.2 Inventiva Contract number (FI No): 93637 Contract number (FI No): 94751 Serapis No: 2021-0353 INVENTIVA (EGFF) Finance Contract between the European Investment Bank and Inventiva S.A. 16 May 2022 WHEREAS: 6 Article 1 7 1.1 Interpretation 7 Article 2 16 2.1 Amount of Credit 16 2.2 Disbursement procedure 16 2.2.1 Tranches 16 2.2.2 Disbursement Offer 16 2.2.3 Disbursement Acceptance 16 2

May 16, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of May 2022 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of May 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant?s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive off

May 16, 2022 EX-99.1

Inventiva secures a €50 million credit facility from the European Investment Bank

Exhibit 99.1 PRESS RELEASE Inventiva secures a ?50 million credit facility from the European Investment Bank ? This credit facility is intended to support the progress and expansion of Inventiva?s pipeline ? The credit facility consists of two tranches of ?25 million each ? Credit agreement is part of the European Investment Bank?s strategy to support biotech companies developing a high-level of e

May 16, 2022 EX-99.1

Inventiva reports 2022 First Quarter Financial Information and provides clinical development update

EXHIBIT 99.1 Inventiva reports 2022 First Quarter Financial Information and provides clinical development update Cash position2 at ?80.5m as of March 31, 2022 The Group did not generate any revenue in Q1 2022 Signature of a ?50 million bullet credit facility agreement with the European Investment Bank Update on lanifibranor recruitment timing for Phase III trial in patients with NASH, as well as f

May 16, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2022 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant's name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address, including zip code, and t

May 2, 2022 EX-99.1

Société Anonyme with a Board of Directors With a share capital of EUR 408,735.51 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting

Exhibit 99.1 Translation for information purpose only INVENTIVA Soci?t? Anonyme with a Board of Directors With a share capital of EUR 408,735.51 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting The shareholders of INVENTIVA are informed that the Ordinary and Extraordinary General Meeting will be held on May 19, 2022 at 2 p.m., at:

May 2, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of May 2022 Commission File Number: 001-39374

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of May 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant?s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive off

April 28, 2022 EX-99.2

Statement of total voting rights and shares forming the company’s share capital as of April 11, 2022 Article R. 22-10-23 of the French Commercial Code Market : Euronext Paris ISIN code / Mnemo : FR0013233012 / IVA Web site : www.inventivapharma.com

Exhibit 99.2 PRESS RELEASE Statement of total voting rights and shares forming the company?s share capital as of April 11, 2022 Article R. 22-10-23 of the French Commercial Code Market : Euronext Paris ISIN code / Mnemo : FR0013233012 / IVA Web site : www.inventivapharma.com Date Number of Shares Outstanding Total voting rights, gross (1) Total voting rights, net (2) April 11, 2022 40 873 551 52 8

April 28, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of April 2022 Commission File Number: 001-3937

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of April 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant?s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive o

April 28, 2022 EX-99.1

Combined General Meeting of May 19, 2022 Availability of the preparatory documents

Exhibit 99.1 PRESS RELEASE Combined General Meeting of May 19, 2022 Availability of the preparatory documents Daix (France), Long Island City (New York, United States), April 28, 2022 ? Inventiva (Euronext Paris and Nasdaq: IVA), a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of non-alcoholic steatohepatitis (NASH) and other

April 25, 2022 EX-99.2

Ordinary and Extraordinary General Meeting of Inventiva S.A. to be held on May 19, 2022 Instructions for beneficial owners of American Depositary Shares (“ADSs”)

Exhibit 99.2 INVENTIVA Ordinary and Extraordinary General Meeting of Inventiva S.A. to be held on May 19, 2022 Instructions for beneficial owners of American Depositary Shares (?ADSs?) Beneficial owners of ADSs who wish to submit their votes in connection with the General Meeting of Inventiva to be held on May 19, 2022 should consult the voting instruction form delivered to them by The Bank of New

April 25, 2022 EX-99.1

19570 Inventiva SA VIF Proof 3 Ordinary and Extraordinary General Meeting of Inventiva S.A. Date: May 19, 2022 See Voting Instruction On Reverse Side. Please make your marks like this: x Use pen only Ordinary and Extraordinary General Meeting of Inve

Exhibit 99.1 19570 Inventiva SA VIF Proof 3 Ordinary and Extraordinary General Meeting of Inventiva S.A. Date: May 19, 2022 See Voting Instruction On Reverse Side. Please make your marks like this: x Use pen only Ordinary and Extraordinary General Meeting of Inventiva S.A. to be held May 19, 2022 For Holders as of April 11, 2022 All votes must be received by 5:00 pm, Eastern Time May 13, 2022. Cop

April 25, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of April 2022 Commission File Number: 001-3937

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of April 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant?s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive o

April 11, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of April 2022 Commission File Number: 001-3937

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of April 2022 Commission File Number: 001-39374 Inventiva S.A. (Translation of registrant?s name into English) 50 rue de Dijon 21121 Daix France +33 3 80 44 75 00 (Address of principal executive o

April 11, 2022 EX-99.1

Société Anonyme with a Board of Directors With a share capital of EUR 408,735.51 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting to the Ordinary and Extraordinary General Meeting dat

Exhibit 99.1 Translation for information purpose only INVENTIVA Soci?t? Anonyme with a Board of Directors With a share capital of EUR 408,735.51 Registered Office: 50, Rue de Dijon, 21121 Daix 537 530 255 Trade and Companies Register of Dijon Notice of meeting to the Ordinary and Extraordinary General Meeting dated May 19, 2022 The shareholders of INVENTIVA are informed that the Ordinary and Extra

March 11, 2022 EX-12.2

Certification by the Principal Financial Officer pursuant to Securities Exchange Act Rules 13a-14(a) and 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Exhibit 12.2 SECTION 302 CERTIFICATION I, Jean Volatier, certify that: 1. I have reviewed this annual report on Form 20-F of Inventiva S.A.; 2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with res

March 11, 2022 20-F

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 20-F

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

March 11, 2022 EX-13.1

Certification by the Principal Executive Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

Exhibit 13.1 CERTIFICATION OF CEO PURSUANT TO 18 U.S.C. SECTION 1350 AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002 Pursuant to the requirement set forth in Rule 13a-14(b) of the Securities Exchange Act of 1934, as amended, (the “Exchange Act”) and Section 1350 of Chapter 63 of Title 18 of the United States Code (18 U.S.C. §1350), Frédéric Cren, Chief Executive Officer of Inv

March 11, 2022 EX-13.2

Certification by the Principal Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

Exhibit 13.2 CERTIFICATION OF CFO PURSUANT TO 18 U.S.C. SECTION 1350 AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002 Pursuant to the requirement set forth in Rule 13a-14(b) of the Securities Exchange Act of 1934, as amended, (the “Exchange Act”) and Section 1350 of Chapter 63 of Title 18 of the United States Code (18 U.S.C. §1350), Jean Volatier, Chief Financial Officer of Inv

March 11, 2022 EX-12.1

Certification by the Principal Executive Officer pursuant to Securities Exchange Act Rules 13a-14(a) and 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Exhibit 12.1 SECTION 302 CERTIFICATION I, Frédéric Cren, certify that: 1. I have reviewed this annual report on Form 20-F of Inventiva S.A.; 2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with res

March 11, 2022 EX-1.1

Bylaws of the registrant (English translation).

EX-1.1 2 iva-20201231xex1d1.htm EXHIBIT 1.1 Exhibit 1.1 INVENTIVA Société anonyme à Conseil d’administration with a share capital of €408,735.51 Registered office: 50 Rue de Dijon, 21121 Daix, France Dijon Trade and Companies Register 537 530 255 ARTICLES OF ASSOCIATION UPDATED TO REFLECT THE CHIEF EXECUTIVE OFFICER’S DECISIONS OF 1st October 2021 PART I FORM - NAME - OBJECTS - REGISTERED OFFICE -

March 11, 2022 EX-15.1

Consent of KPMG S.A.

Exhibit 15.1 ? ? ? ? ? ? KPMG Audit Tour EQHO 2 Avenue Gambetta CS 60055 92066 Paris la D?fense Cedex France ? T?l?phone :+33 (0)1 55 68 68 68 T?l?copie :+33 (0)1 55 68 73 00 Site internet :www.kpmg.fr ? ? Consent of Independent Registered Public Accounting Firm The Board of Directors Inventiva S.A. We consent to the incorporation by reference in the registration statement (No. 333-258369) on Form

March 8, 2022 EX-99.1

Inventiva announces that its IND application for the Phase II combination trial with lanifibranor and empagliflozin in patients with NASH and T2D has been accepted by the FDA

EXHIBIT 99.1 Inventiva announces that its IND application for the Phase II combination trial with lanifibranor and empagliflozin in patients with NASH and T2D has been accepted by the FDA FDA assessment concludes that the Phase II combination trial, LEGEND, may proceed The initiation of the trial is planned for H1 2022 and the publication of topline results is expected for H2 2023 Daix (France), L

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