SDGR / Schrödinger, Inc. - Документы SEC, Годовой отчет, Доверенное заявление

Шредингер, Инк.
US ˙ NasdaqGS ˙ US80810D1037

Основная статистика
CIK 1490978
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Schrödinger, Inc.
SEC Filings (Chronological Order)
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August 6, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 6, 2025 Schrodinger, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 6, 2025 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization) (I

August 6, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

August 6, 2025 EX-99.1

Schrödinger Reports Second Quarter 2025 Financial Results Second Quarter Total Revenue of $54.8 Million, Software Revenue of $40.5 Million Maintains Full Year 2025 Revenue Growth Guidance and Lowers Operating Expense Guidance Company to Complete Phas

Exhibit 99.1 Schrödinger Reports Second Quarter 2025 Financial Results Second Quarter Total Revenue of $54.8 Million, Software Revenue of $40.5 Million Maintains Full Year 2025 Revenue Growth Guidance and Lowers Operating Expense Guidance Company to Complete Phase 1 Data Package for SGR-1505 While Exploring Strategic Opportunities for Clinical Development Initial Clinical Data for SGR-3515 and SGR

August 6, 2025 EX-10.1

Seventh Amended and Restated Director Compensation Policy

Exhibit 10.1 Schrödinger, Inc. Seventh Amended and Restated Director Compensation Policy Effective as of June 27, 2025 (the “Effective Date”) The non-employee directors of Schrödinger, Inc. (the “Company”) shall receive the following compensation for their service as members of the Board of Directors (the “Board”) of the Company. Director Compensation Our goal is to provide compensation for our no

June 18, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 18, 2025 Schrodinger, Inc. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 18, 2025 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization) (I.

May 20, 2025 EX-10.1

Employment Agreement, dated May 16, 2025, by and between Schrödinger, Inc. and Richie Jain

EX-10.1 Exhibit 10.1 EMPLOYMENT AGREEMENT THIS EMPLOYMENT AGREEMENT (the “Agreement”), is made as of May 16, 2025 by and between Schrödinger, Inc. (the “Company,” and, together with its subsidiaries and Affiliates (as hereinafter defined), the “Schrödinger Companies”), and Rachit (Richie) Jain (the “Executive”) (together, the “Parties”). RECITALS WHEREAS, the Company desires to employ the Executiv

May 20, 2025 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 16, 2025 Schrödinger, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-39206 95-4284541 (State or Other Jurisdiction of Incorporation) (Commission File Number)

May 19, 2025 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 19, 2025 Schrödinger, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-39206 95-4284541 (State or Other Jurisdiction of Incorporation) (Commission File Number)

May 7, 2025 EX-99.1

2021 Inducement Equity Incentive Plan, as amended.

Exhibit 99.1 Schrödinger, Inc. 2021 INDUCEMENT EQUITY INCENTIVE PLAN 1. Purpose The purpose of this 2021 Inducement Equity Incentive Plan (the “Plan”) of Schrödinger, Inc., a Delaware corporation (the “Company”), is to advance the interests of the Company’s stockholders by enhancing the Company’s ability to attract, retain and motivate persons who are expected to make important contributions to th

May 7, 2025 EX-10.1

ixth Amended and Restated Director C

Exhibit 10.1 Schrödinger, Inc. Sixth Amended and Restated Director Compensation Policy Adopted on April 19, 2025 The non-employee directors of Schrödinger, Inc. (the “Company”) shall receive the following compensation for their service as members of the Board of Directors (the “Board”) of the Company. Director Compensation Our goal is to provide compensation for our non-employee directors in a man

May 7, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 7, 2025 Schrodinger, Inc. (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 7, 2025 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization) (I.R.

May 7, 2025 EX-FILING FEES

Filing Fee Table.

Calculation of Filing Fee Tables S-8 Schrodinger, Inc. Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee 1 Equity Common Stock, $0.01 par value per share Other 100,000 $ 24.38 $ 2,438,000.00 0.0001531 $ 373.26 Total Offering Amou

May 7, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

May 7, 2025 EX-99.1

Schrödinger Reports Strong First Quarter 2025 Financial Results First Quarter Total Revenue of $59.6 Million, Software Revenue of $48.8 Million Initial SGR-1505 Phase 1 Clinical Data to be Presented in June Maintains 2025 Financial Guidance

Exhibit 99.1 Schrödinger Reports Strong First Quarter 2025 Financial Results First Quarter Total Revenue of $59.6 Million, Software Revenue of $48.8 Million Initial SGR-1505 Phase 1 Clinical Data to be Presented in June Maintains 2025 Financial Guidance New York, May 7, 2025 – Schrödinger, Inc. (Nasdaq: SDGR) today announced financial results for the quarter ended March 31, 2025. “We are very plea

May 7, 2025 S-8

As filed with the Securities and Exchange Commission on May 7, 2025

As filed with the Securities and Exchange Commission on May 7, 2025 Registration No.

April 24, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defin

April 24, 2025 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) x Defin

April 11, 2025 EX-99.1

NOTICE OF PENDENCY OF SETTLEMENT OF DERIVATIVE ACTION

Exhibit 99.1 SUPREME COURT OF THE STATE OF NEW YORK COUNTY OF NEW YORK ARNAT ABZHANOV, derivatively on behalf of SCHRODINGER, INC., Plaintiff, v. MICHAEL LYNTON, JEFFREY CHODAKEWITZ, RICHARD A. FRIESNER, GARY GINSBERG, ROSANA KAPELLER-LIBERMANN, ARUN OBEROI, GARY SENDER, NANCY THORNBERRY, and RAMY FARID, Defendants, and SCHRODINGER, INC., Nominal Defendant. Index No.: 655000/2024 NOTICE OF PENDENC

April 11, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 11, 2025 Schrodinger, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 11, 2025 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization) (I

March 10, 2025 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 7, 2025 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization) (I.

February 26, 2025 EX-99.1

Schrödinger Reports Strong Fourth Quarter and Full-Year 2024 Financial Results Achieved 2024 Software Revenue of $180.4 Million, a 13.3% Increase Over 2023 Expects Software Revenue Growth of 10% to 15% and Drug Discovery Revenue of $45-50 Million in

Exhibit 99.1 Schrödinger Reports Strong Fourth Quarter and Full-Year 2024 Financial Results Achieved 2024 Software Revenue of $180.4 Million, a 13.3% Increase Over 2023 Expects Software Revenue Growth of 10% to 15% and Drug Discovery Revenue of $45-50 Million in 2025 Announces Expanded Research Collaboration with Eli Lilly and Company On Track to Report Initial Phase 1 Data from Three Proprietary

February 26, 2025 EX-19.1

Schrödinger, Inc. Global Insider Trading Policy

Approved by the Board of Directors on February 19, 2025 Exhibit 19.1 SCHRÖDINGER, INC. Global Insider Trading Policy 1. BACKGROUND AND PURPOSE 1.1 Why Have We Adopted This Policy? The U.S. federal securities laws prohibit any member of the Board of Directors (a “Director”), officer (as defined in Rule 16a-1(f) under the Securities Exchange Act of 1934 (the “Exchange Act”), an “executive officer”)

February 26, 2025 EX-10.48

dated as of November 11, 2024

CONFIDENTIAL EXECUTION COPY Exhibit 10.48 Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential. Double asterisks denote omissions. RESEARCH COLLABORATION AND LICENSE AGREEMENT BY AND BETWEEN SCHRӦDINGER, INC. AND NOVARTIS PHARMA AG dated as of November 11, 2024

February 26, 2025 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 OR ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-39206 Schrodinger, I

February 26, 2025 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 26, 2025 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization)

February 26, 2025 EX-21.1

Subsidiaries of the Registrant

Exhibit 21.1 List of Subsidiaries Name Jurisdiction of Incorporation Schrödinger, LLC Delaware Schrödinger GmbH Germany Synaptic Science LLC Delaware Schrödinger, KK Japan Reo Discovery Limited Ireland Schrödinger Technologies Ltd United Kingdom Schrödinger India Private Limited India Schrodinger Korea LLC South Korea

November 13, 2024 SC 13G

SDGR / Schrödinger, Inc. / Rubric Capital Management LP - SC 13G Passive Investment

SC 13G 1 tm2427812d11sc13.htm SC 13G SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Schrodinger, Inc. (Name of Issuer) Common Stock, $0.01 par value (Title of Class of Securities) 80810D103 (CUSIP Number) September 30, 2024 (Date of event which requires filing of this statement) Check the appropriate box to designa

November 12, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

November 12, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 11, 2024 Schrodinger, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 11, 2024 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization)

November 12, 2024 EX-99.1

Schrödinger Reports Third Quarter 2024 Financial Results Schrödinger to Receive $150 Million Upfront for New Multi-Target Collaboration with Novartis Third Quarter Total Revenue of $35.3 Million, Software Revenue of $31.9 Million Updates 2024 Financi

Exhibit 99.1 Schrödinger Reports Third Quarter 2024 Financial Results Schrödinger to Receive $150 Million Upfront for New Multi-Target Collaboration with Novartis Third Quarter Total Revenue of $35.3 Million, Software Revenue of $31.9 Million Updates 2024 Financial Guidance New York, November 12, 2024 – Schrödinger, Inc. (Nasdaq: SDGR) today announced financial results for the third quarter of 202

November 12, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2024 Schrodinger, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2024 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization)

September 12, 2024 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 11, 2024 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization

September 12, 2024 EX-10.1

Master License Agreement, dated as of September 11, 2024, by and between Schrödinger, LLC and The Trustees of Columbia University.

Exhibit 10.1 EXECUTION COPY Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential. Double asterisks denote omissions. MASTER LICENSE AGREEMENT This MASTER LICENSE AGREEMENT (“Master License Agreement”), dated September 11, 2024 (the “Effective Date”), is made by

July 31, 2024 EX-10.4

0 Employee Stock Purchase Plan

Exhibit 10.4 Schrödinger, Inc. 2020 EMPLOYEE STOCK PURCHASE PLAN The purpose of this 2020 Employee Stock Purchase Plan (this “Plan”) is to provide eligible employees of Schrödinger, Inc. (the “Company”) and certain of its subsidiaries with opportunities to purchase shares of the Company’s common stock, $0.01 par value per share (the “Common Stock”), commencing at such time and on such dates as the

July 31, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 31, 2024 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization) (I.

July 31, 2024 S-8

As filed with the Securities and Exchange Commission on July 31, 2024

As filed with the Securities and Exchange Commission on July 31, 2024 Registration No.

July 31, 2024 EX-FILING FEES

Table 1: Newly Registered Securities

Calculation of Filing Fee Tables S-8 Schrodinger, Inc. Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee 1 Equity Common Stock, $0.01 par value per share Other 5,413,155 $ 22.51 $ 121,850,119.05 0.0001476 $ 17,985.08 Total Offeri

July 31, 2024 EX-10.1

Consultant Agreement, dated July 1, 1999, between Schrödinger, Inc. and Richard A. Friesner, as amended

Exhibit 10.1 CONSULTANT AGREEMENT AGREEMENT made as of the 1st day of July, 1999 between SCHRÖDINGER, INC., having its place of business at 1500 SW First Avenue, Suite 1180, Portland, Oregon 97201-5881 (“Company”) and RICHARD A. FRIESNER, residing at [**] (“Consultant”). RECITALS A. Company is engaged in the business of designing, developing, distributing, selling, licensing, leasing and servicing

July 31, 2024 EX-3.1

estated Certificate of Incorporation, as amended

Exhibit 3.1 RESTATED CERTIFICATE OF INCORPORATION OF SCHRÖDINGER, INC. Schrödinger, Inc., a corporation organized and existing under the General Corporation Law of the State of Delaware, does hereby certify that the name of the corporation is Schrödinger, Inc. and the original certificate of incorporation of the corporation was filed with the Secretary of State of the State of Delaware on May 22,

July 31, 2024 EX-10.3

Incentive Plan, as amended

Exhibit 10.3 SCHRÖDINGER, INC. 2022 EQUITY INCENTIVE PLAN 1. Purpose The purpose of this 2022 Equity Incentive Plan (the “Plan”) of Schrödinger, Inc., a Delaware corporation (the “Company”), is to advance the interests of the Company’s stockholders by enhancing the Company’s ability to attract, retain and motivate persons who are expected to make important contributions to the Company and by provi

July 31, 2024 EX-99.1

Schrödinger Reports Strong Second Quarter 2024 Financial Results Second Quarter Total Revenue of $47.3 Million, Software Revenue of $35.4 Million Launches Major Initiative to Expand Application of Computational Tools for Predictive Toxicology Initial

Exhibit 99.1 Schrödinger Reports Strong Second Quarter 2024 Financial Results Second Quarter Total Revenue of $47.3 Million, Software Revenue of $35.4 Million Launches Major Initiative to Expand Application of Computational Tools for Predictive Toxicology Initial Clinical Data Expected for SGR-1505 in 1H25, SGR-2921 and SGR-3515 Data in 2H25 New York, July 31, 2024 – Schrödinger, Inc. (Nasdaq: SDG

July 31, 2024 EX-10.2

, by and between the Registrant and SPUSV5 1540 Broadway, LLC

Exhibit 10.2 SECOND AMENDMENT TO LEASE (Schrödinger, Inc. – 1540 Broadway) THIS SECOND AMENDMENT TO LEASE (this “Second Amendment”) is dated effective and for identification purposes as of June 13, 2024, and is made by and between SPUSV5 1540 BROADWAY, LLC, a Delaware limited liability company (“Landlord”), and SCHRÖDINGER, INC., a Delaware corporation (“Tenant”). RECITALS: WHEREAS, pursuant to th

July 31, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

June 18, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 18, 2024 Schrodinger, Inc. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 18, 2024 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization) (I.

May 30, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Defin

May 1, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

May 1, 2024 EX-99.1

Schrödinger Reports First Quarter 2024 Financial Results First Quarter Total Revenue of $36.6 Million, Software Revenue of $33.4 Million Announces FDA Clearance of Investigational New Drug Application for SGR-3515, a Novel Wee1/Myt1 Inhibitor SGR-150

Exhibit 99.1 Schrödinger Reports First Quarter 2024 Financial Results First Quarter Total Revenue of $36.6 Million, Software Revenue of $33.4 Million Announces FDA Clearance of Investigational New Drug Application for SGR-3515, a Novel Wee1/Myt1 Inhibitor SGR-1505 and SGR-2921 on Track for Initial Phase 1 Data Readouts in Late 2024 or 2025 New York, May 1, 2024 – Schrödinger, Inc. (Nasdaq: SDGR),

May 1, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 1, 2024 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization) (I.R.

May 1, 2024 EX-10.3

d Restated Director C

Exhibit 10.3 Schrödinger, Inc. Fifth Amended and Restated Director Compensation Policy Adopted on April 8, 2024 Effective as of January 1, 2024, the non-employee directors of Schrödinger, Inc. (the “Company”) shall receive the following compensation for their service as members of the Board of Directors (the “Board”) of the Company. Director Compensation Our goal is to provide compensation for our

April 25, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defin

April 25, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) x Defin

April 11, 2024 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: x Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Defin

February 29, 2024 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 28, 2024 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization)

February 29, 2024 EX-1.1

Amended and Restated Sales Agreement, dated as of February 28, 2024, by and between Schrödinger, Inc. and Leerink Partners LLC

Exhibit 1.1 Execution Version SCHRÖDINGER, INC. Shares of Common Stock ($0.01 par value per share) AMENDED AND RESTATED SALES AGREEMENT February 28, 2024 LEERINK PARTNERS LLC 1301 Avenue of the Americas, 12th Floor New York, New York 10019 Ladies and Gentlemen: Reference is made to that certain Sales Agreement, entered into as of May 24, 2023 (the “Original Sales Agreement”) by and between Schrödi

February 28, 2024 EX-99.1

Schrödinger Reports Strong Fourth Quarter and Full-Year 2023 Financial Results Achieved Fourth Quarter Software Revenue of $68.7 Million, a 44% Increase Over Fourth Quarter 2022 Delivered 20% Annual Total Revenue Growth, with Total Revenue of $216.7

Exhibit 99.1 Schrödinger Reports Strong Fourth Quarter and Full-Year 2023 Financial Results Achieved Fourth Quarter Software Revenue of $68.7 Million, a 44% Increase Over Fourth Quarter 2022 Delivered 20% Annual Total Revenue Growth, with Total Revenue of $216.7 Million Expects Software Revenue Growth of 6% to 13% in 2024 New York, February 28, 2024 – Schrödinger, Inc. (Nasdaq: SDGR), whose physic

February 28, 2024 EX-10.19

Employment Agreement, dated July 28, 2023, by and between the Registrant and Margaret Dugan

Exhibit 10.19 1540 Broadway, 24th Floor New York, NY 10036 EMPLOYMENT AGREEMENT THIS EMPLOYMENT AGREEMENT (the “Agreement”) is made as of July 27, 2023 by and between Schrödinger, Inc. (the “Company,” and, together with its subsidiaries and Affiliates (as hereinafter defined), the “Schrödinger Companies”) and Margaret Dugan (the “Executive”) (together, the “Parties”). RECITALS WHEREAS, the Company

February 28, 2024 EX-4.4

Form of Subordinated Indenture

Exhibit 4.4 SCHRÖDINGER, INC. and Trustee INDENTURE Dated as of SUBORDINATED DEBT SECURITIES CROSS-REFERENCE TABLE 1 Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 6.09 310(b) 6.08 6.10 310(c) Inapplicable 311(a) 6.13 311(b) 6.13 311(c) Inapplicable 312(a) 4.01 4.04 312(b) 4.04(c) 312(c) 4.04(c) 313(a) 4.03 313(b) 4.03 313(c) 4.03 313(d) 4.03 314(a) 4.02 314(b) Inap

February 28, 2024 EX-4.6

Form of Subordinated Note

Exhibit 4.6 Form of Subordinated Note (FACE OF SECURITY) [Each Global Security shall bear substantially the following legend: UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE REGISTERED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE

February 28, 2024 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 OR ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-39206 Schrodinger, I

February 28, 2024 S-3ASR

As filed with the Securities and Exchange Commission on February 28, 2024

Table of Contents As filed with the Securities and Exchange Commission on February 28, 2024 Registration No.

February 28, 2024 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Schrödinger, Inc.

February 28, 2024 EX-10.1

Amended and Restated Investors’ Rights Agreement, dated as of November 9, 2018, by and among the Registrant and the other parties thereto, as amended

Exhibit 10.1 SCHRÖDINGER, INC. AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT TABLE OF CONTENTS Page 1 Definitions 1 2 Registration Rights 6 2.1 Demand Registration 6 2.2 Company Registration 7 2.3 Underwriting Requirements 8 2.4 Obligations of the Company 9 2.5 Furnish Information 10 2.6 Expenses of Registration 11 2.7 Delay of Registration 11 2.8 Indemnification 11 2.9 Reports Under Exchange A

February 28, 2024 EX-4.3

Form of Senior Indenture

Exhibit 4.3 SCHRÖDINGER, INC. and Trustee INDENTURE Dated as of SENIOR DEBT SECURITIES CROSS-REFERENCE TABLE1 Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 6.09 310(b) 6.08 6.10 310(c) Inapplicable 311(a) 6.13 311(b) 6.13 311(c) Inapplicable 312(a) 4.01 4.04 312(b) 4.04(c) 312(c) 4.04(c) 313(a) 4.03 313(b) 4.03 313(c) 4.03 313(d) 4.03 314(a) 4.02 314(b) Inapplicabl

February 28, 2024 EX-4.5

Form of Senior Note

Exhibit 4.5 Form of Senior Note (FACE OF SECURITY) [Each Global Security shall bear substantially the following legend: UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE REGISTERED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE OF THE

February 28, 2024 EX-1.2

Amended and Restated Sales Agreement, dated as of February 28, 2024, by and between the Registrant and Leerink Partners LLC

Exhibit 1.2 Execution Version SCHRÖDINGER, INC. Shares of Common Stock ($0.01 par value per share) AMENDED AND RESTATED SALES AGREEMENT February 28, 2024 LEERINK PARTNERS LLC 1301 Avenue of the Americas, 12th Floor New York, New York 10019 Ladies and Gentlemen: Reference is made to that certain Sales Agreement, entered into as of May 24, 2023 (the “Original Sales Agreement”) by and between Schrödi

February 28, 2024 EX-97.1

. Clawback Policy

Exhibit 97.1 APPROVED BY THE BOARD NOVEMBER 10, 2023 SCHRÖDINGER, INC. Clawback Policy This Clawback Policy (this “Policy”), adopted by Schrödinger, Inc. (the “Company”), relates to the Company’s right to recover compensation previously paid to specified employees in certain circumstances, including the recovery of Erroneously Awarded Compensation (as defined below) in accordance with Nasdaq Listi

February 28, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 28, 2024 Schrodinger, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 28, 2024 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization)

February 13, 2024 SC 13G/A

SDGR / Schrödinger, Inc. / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv01883-schrodingerincunited.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 4)* Name of issuer: Schrodinger Inc/United States Title of Class of Securities: Common Stock CUSIP Number: 80810D103 Date of Event Which Requires Filing of this Statement: December 29, 2023 Check the appropriate

November 1, 2023 EX-10.1

Amendment #1 to the Independent Contractor Agreement, dated August 14, 2023, by and between the Registrant and Gates Ventures, LLC

Exhibit 10.1 Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. AMENDMENT #1 TO THE INDEPENDENT CONTRACTOR AGREEMENT This Amendment (“Amendment 1”) is effective as of August 14, 2023 (“Amendment 1 Effective Date”) and modifies the

November 1, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

November 1, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 1, 2023 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization)

November 1, 2023 EX-99.1

Schrödinger Reports Third Quarter 2023 Financial Results Delivers Third Quarter Total Revenue of $42.6 Million; Maintains Full-Year 2023 Revenue Guidance Continued Progress for SGR-1505, Healthy Volunteer Data Expected in Fourth Quarter of 2023 Phase

Exhibit 99.1 Schrödinger Reports Third Quarter 2023 Financial Results Delivers Third Quarter Total Revenue of $42.6 Million; Maintains Full-Year 2023 Revenue Guidance Continued Progress for SGR-1505, Healthy Volunteer Data Expected in Fourth Quarter of 2023 Phase 1 Study Initiated for SGR-2921; Discloses PRMT5-MTA Discovery Program BMS Returns Two Programs From Collaboration New York, November 1,

August 3, 2023 EX-99.1

Schrödinger Reports Second Quarter 2023 Financial Results Announces IND Clearance for CDC7 Inhibitor SGR-2921, Continued Progress for MALT1 Inhibitor SGR-1505 Delivers Second Quarter Total Revenue of $35.2 Million Raises 2023 Software Revenue Guidanc

Exhibit 99.1 Schrödinger Reports Second Quarter 2023 Financial Results Announces IND Clearance for CDC7 Inhibitor SGR-2921, Continued Progress for MALT1 Inhibitor SGR-1505 Delivers Second Quarter Total Revenue of $35.2 Million Raises 2023 Software Revenue Guidance and Reduces Drug Discovery Guidance New York, August 2, 2023 – Schrödinger, Inc. (Nasdaq: SDGR), whose physics-based computational plat

August 3, 2023 8-K/A

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K/A (Amendment No. 1) CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 2, 2023 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation

August 2, 2023 EX-99.1

Schrödinger Reports Second Quarter 2023 Financial Results Announces IND Clearance for CDC7 Inhibitor SGR-2921, Continued Progress for MALT1 Inhibitor SGR-1505 Delivers Second Quarter Total Revenue of $35.2 Million Raises 2023 Software Revenue Guidanc

Exhibit 99.1 Schrödinger Reports Second Quarter 2023 Financial Results Announces IND Clearance for CDC7 Inhibitor SGR-2921, Continued Progress for MALT1 Inhibitor SGR-1505 Delivers Second Quarter Total Revenue of $35.2 Million Raises 2023 Software Revenue Guidance and Reduces Drug Discovery Guidance New York, August 2, 2023 – Schrödinger, Inc. (Nasdaq: SDGR), whose physics-based computational plat

August 2, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

August 2, 2023 EX-10.1

Consultant Agreement, dated July 1, 1999, between Schrödinger, Inc. and Richard A. Friesner, as amended

Exhibit 10.1 CONSULTANT AGREEMENT AGREEMENT made as of the 1st day of July, 1999 between SCHRÖDINGER, INC., having its place of business at 1500 SW First Avenue, Suite 1180, Portland, Oregon 97201-5881 (“Company”) and RICHARD A. FRIESNER, residing at [**] (“Consultant”). RECITALS A. Company is engaged in the business of designing, developing, distributing, selling, licensing, leasing and servicing

August 2, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 2, 2022 Schrodinger, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 2, 2022 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization) (I

July 10, 2023 SC 13G/A

SDGR / Schrodinger Inc / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 3)* Name of issuer: Schrodinger Inc. Title of Class of Securities: Common Stock CUSIP Number: 80810D103 Date of Event Which Requires Filing of this Statement: June 30, 2023 Check the appropriate box to designate the rule pursuant to which this Schedule is filed: ☒ Rule 1

June 15, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 15, 2023 Schrodinger, Inc. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 15, 2023 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization) (I.

May 24, 2023 EX-FILING FEES

Calculation of Filing Fee Tables Form 424(b)(5) (Form Type) Schrödinger, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Fo

EX-FILING FEES Exhibit 107 Calculation of Filing Fee Tables Form 424(b)(5) (Form Type) Schrödinger, Inc.

May 24, 2023 424B5

Up to $250,000,000 Common Stock

424B5 Table of Contents As Filed Pursuant to Rule 424(b)(5) Registration No. 333-253865 PROSPECTUS SUPPLEMENT (To Prospectus Dated March 4, 2021) Up to $250,000,000 Common Stock We have entered into a sales agreement, or the sales agreement, with SVB Securities LLC, or SVB Securities, dated May 24, 2023, relating to the sale of shares of our common stock, par value $0.01 per share. In accordance w

May 24, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 24, 2023 Schrodinger, Inc. (E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 24, 2023 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization) (I.R

May 24, 2023 EX-1.1

Sales Agreement, dated as of May 24, 2023, by and between Schrödinger, Inc. and SVB Securities LLC

Exhibit 1.1 Execution Version SCHRÖDINGER, INC. Shares of Common Stock ($0.01 par value per share) SALES AGREEMENT May 24, 2023 SVB SECURITIES LLC 1301 Avenue of the Americas, 12th Floor New York, New York 10019 Ladies and Gentlemen: Schrödinger, Inc., a Delaware corporation (the “Company”), confirms its agreement (this “Agreement”) with SVB Securities LLC (the “Agent”), as follows: 1.Issuance and

May 4, 2023 EX-99.1

Schrödinger Reports Strong First Quarter 2023 Financial Results Delivered First Quarter Total Revenue of $64.8 Million, Driven by Strong Drug Discovery Revenue of $32.6 Million Reports First Subjects Enrolled in Both Ongoing Phase 1 Study of MALT1 In

Exhibit 99.1 Schrödinger Reports Strong First Quarter 2023 Financial Results Delivered First Quarter Total Revenue of $64.8 Million, Driven by Strong Drug Discovery Revenue of $32.6 Million Reports First Subjects Enrolled in Both Ongoing Phase 1 Study of MALT1 Inhibitor SGR-1505 and Newly Initiated Phase 1 Study in Healthy Subjects Cash Position Significantly Strengthened by $147.3 Million Distrib

May 4, 2023 EX-10.2

Form of Restricted Stock Unit Agreement for Non-U.S. Participants under 2021 Inducement Equity Incentive Plan

Exhibit 10.2 Schrödinger, Inc. RESTRICTED STOCK UNIT AGREEMENT FOR NON-U.S. PARTICIPANTS Granted under 2021 Inducement Equity Incentive Plan Schrödinger, Inc. (the “Company”) hereby grants the following restricted stock units pursuant to its 2021 Inducement Equity Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of recipient (the “Participant”):

May 4, 2023 EX-10.1

Form of Restricted Stock Unit Agreement for U.S. Participants under 2021 Inducement Equity Incentive Plan

Exhibit 10.1 Schrödinger, Inc. RESTRICTED STOCK UNIT AGREEMENT Granted under 2021 Inducement Equity Incentive Plan Schrödinger, Inc. (the “Company”) hereby grants the following restricted stock units pursuant to its 2021 Inducement Equity Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of recipient (the “Participant”): Grant Date: Number of res

May 4, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 4, 2023 Schrodinger, Inc. (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 4, 2023 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization) (I.R.

May 4, 2023 EX-10.3

Fourth Amended and Restated Director Compensation Policy

Exhibit 10.3 Schrödinger, Inc. Fourth Amended and Restated Director Compensation Policy Adopted on April 12, 2023 Effective as of January 1, 2023, the non-employee directors of Schrödinger, Inc. (the “Company”) shall receive the following compensation for their service as members of the Board of Directors (the “Board”) of the Company. Director Compensation Our goal is to provide compensation for o

May 4, 2023 10-Q

Form 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

April 27, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defin

April 27, 2023 DEF 14A

Definitive Proxy Statement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) x Defin

April 13, 2023 8-K

Form 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 12, 2023 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization) (I

April 13, 2023 EX-3.1

Amended and Restated Bylaws of Schrödinger, Inc.

AMENDED AND RESTATED BYLAWS OF SCHRÖDINGER, INC. TABLE OF CONTENTS Page ARTICLE I STOCKHOLDERS 1 1.1 Place of Meetings 1 1.2 Annual Meeting 1 1.3 Special Meetings. 1 1.4 Record Date for Stockholder Meetings. 4 1.5 Notice of Meetings. 5 1.6 Voting List 6 1.7 Quorum. 6 1.8 Adjournments 7 1.9 Voting and Proxies. 7 1.10 Action at Meeting. 8 1.11 Nomination of Directors. 9 1.12 Notice of Other Business

February 28, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 28, 2023 Schrodinger, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 28, 2023 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization)

February 28, 2023 EX-10.40

First Amendment to Collaboration and License Agreement, dated December 21, 2022, by and between the Registrant and Bristol-Myers Squibb Company

Exhibit 10.40 Execution Version Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential. Triple asterisks denote omissions. FIRST AMENDMENT TO COLLABORATION AND LICENSE AGREEMENT This First Amendment (this “First Amendment”) effective as of December 21, 2022 (the

February 28, 2023 10-K

Form 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 OR ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-39206 Schrodinger, I

February 28, 2023 EX-21.1

Subsidiaries of the Registrant

Exhibit 21.1 List of Subsidiaries Name Jurisdiction of Incorporation Schrödinger, LLC Delaware Schrödinger GmbH Germany Synaptic Science LLC Delaware Schrödinger, KK Japan Reo Discovery Limited Ireland Faxian Therapeutics, LLC Delaware Schrödinger Technologies Ltd United Kingdom Schrödinger India Private Limited India Schrodinger Korea LLC South Korea XTAL BioStructures, Inc. Massachusetts

February 28, 2023 EX-99.1

Schrödinger Reports Strong Fourth Quarter and Full-Year 2022 Financial Results Delivered 31% Annual Total Revenue Growth, with Total Revenue of $181.0 Million Achieved Fourth Quarter Software Revenue of $47.8 Million, a 24% Increase Over Fourth Quart

Exhibit 99.1 Schrödinger Reports Strong Fourth Quarter and Full-Year 2022 Financial Results Delivered 31% Annual Total Revenue Growth, with Total Revenue of $181.0 Million Achieved Fourth Quarter Software Revenue of $47.8 Million, a 24% Increase Over Fourth Quarter 2021 Expects Continued Revenue Growth and Reduced Cash Burn in 2023 New York, February 28, 2023 – Schrödinger, Inc. (Nasdaq: SDGR), wh

February 28, 2023 EX-10.15

Employment Agreement, dated March 17, 2003, by and between the Registrant and Jenny Herman

Exhibit 10.15 Schrödinger, Inc. Employment Agreement This Employment Agreement ("Agreement") is dated March 17, 2003 and effective as of the Employment Commencement Date set forth in Section 1 below ("Effective Date") by and between Schrödinger, Inc., a Delaware corporation ("Company"), and Jenny Herman ("Employee"). WHEREAS, the Company is currently in the business of (i) designing, developing, d

February 10, 2023 SC 13G

SDGR / Schrodinger Inc / ARK Investment Management LLC - SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

February 9, 2023 SC 13G/A

SDGR / Schrodinger Inc / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv01851-schrodingerincunited.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 2)* Name of issuer: Schrodinger Inc./United States Title of Class of Securities: Common Stock CUSIP Number: 80810D103 Date of Event Which Requires Filing of this Statement: December 30, 2022 Check the appropriate

November 3, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 3, 2022 Schrodinger, Inc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 3, 2022 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization)

November 3, 2022 EX-FILING FEES

Filing Fee Table.

EX-FILING FEES 2 sdgr-formsx8xex107xfilingf.htm EX-FILING FEES Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Schrödinger, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1-Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Am

November 3, 2022 EX-99.1

Schrödinger Reports Third Quarter 2022 Financial Results Total Revenue Growth of 24 Percent Over Third Quarter of 2021, Driven by Continued Progress Across Drug Discovery Portfolio Full-Year 2022 Revenue Guidance Range Narrowed with Mix Shifting Towa

Exhibit 99.1 Schrödinger Reports Third Quarter 2022 Financial Results Total Revenue Growth of 24 Percent Over Third Quarter of 2021, Driven by Continued Progress Across Drug Discovery Portfolio Full-Year 2022 Revenue Guidance Range Narrowed with Mix Shifting Toward Drug Discovery Phase 1 Clinical Trial of MALT1 Inhibitor, SGR-1505, Open for Patient Enrollment New Preclinical Data for CDC7 Inhibito

November 3, 2022 EX-99.1

2021 Inducement Equity Incentive Plan, as amended.

Exhibit 99.1 Schr?dinger, Inc. 2021 INDUCEMENT EQUITY INCENTIVE PLAN 1. Purpose The purpose of this 2021 Inducement Equity Incentive Plan (the ?Plan?) of Schr?dinger, Inc., a Delaware corporation (the ?Company?), is to advance the interests of the Company?s stockholders by enhancing the Company?s ability to attract, retain and motivate persons who are expected to make important contributions to th

November 3, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

November 3, 2022 EX-10.4

2021 Inducement Equity Incentive Plan, as amended

Exhibit 10.4 Schrödinger, Inc. 2021 INDUCEMENT EQUITY INCENTIVE PLAN 1. Purpose The purpose of this 2021 Inducement Equity Incentive Plan (the “Plan”) of Schrödinger, Inc., a Delaware corporation (the “Company”), is to advance the interests of the Company’s stockholders by enhancing the Company’s ability to attract, retain and motivate persons who are expected to make important contributions to th

November 3, 2022 EX-10.1

Consultant Agreement, dated July 1, 1999, between the Registrant and Richard A. Friesner, as amended

Exhibit 10.1 CONSULTANT AGREEMENT AGREEMENT made as of the 1st day of July, 1999 between SCHRÖDINGER, INC., having its place of business at 1500 SW First Avenue, Suite 1180, Portland, Oregon 97201-5881 (“Company”) and RICHARD A. FRIESNER, residing at [**] (“Consultant”). RECITALS A. Company is engaged in the business of designing, developing, distributing, selling, licensing, leasing and servicing

November 3, 2022 S-8

As filed with the Securities and Exchange Commission on November 3, 2022

S-8 1 sdgr-formsx8xinducementpla.htm S-8 As filed with the Securities and Exchange Commission on November 3, 2022 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Schrödinger, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or Other Jurisdiction of In

August 18, 2022 EX-10.1

Employment Agreement, dated August 16, 2022, by and between the Registrant and Geoffrey Porges

EX-10.1 2 sdgr-ex1017.htm EX-10.1 1540 Broadway, 24th Floor New York, NY 10036 Exhibit 10.1 Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential. Double asterisks denote omissions. EMPLOYMENT AGREEMENT THIS EMPLOYMENT AGREEMENT (the “Agreement”), is made as of

August 18, 2022 EX-10.2

Amended and Restated Executive Severance and Change in Control Benefits Plan, as amended

Exhibit 10.2 Schr?dinger, Inc. Amended and Restated Executive Severance and Change in Control Benefits Plan, as amended August 16, 2022 1.Establishment of Plan. Schr?dinger, Inc., a Delaware corporation, hereby establishes an unfunded severance benefits plan (the ?Plan?) that is intended to be a welfare benefit plan within the meaning of Section 3(1) of ERISA. The Plan is in effect for Covered Emp

August 18, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 16, 2022 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or other jurisdiction of incorporation or organization) 001-39206 (

August 4, 2022 EX-10.3

Form of Option Agreement for Non-U.S. Participants under the 2021 Inducement Equity Incentive Plan

Exhibit 10.3 Schr?dinger, Inc. NONSTATUTORY STOCK OPTION AGREEMENT FOR NON-U.S. PARTICIPANTS Granted under the 2021 Inducement Equity Incentive Plan Schr?dinger, Inc. (the ?Company?) hereby grants the following stock option pursuant to its 2021 Inducement Equity Incentive Plan. The terms and conditions attached hereto are also a part thereof. Notice of Grant Name of optionee (the ?Participant?): G

August 4, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

August 4, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 4, 2022 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or other jurisdiction of incorporation or organization) 001-39206 (C

August 4, 2022 EX-10.1

First Amendment to Lease, dated May 19, 2022, by and between the Registrant and SPUSV5 1540 Broadway, LLC

Exhibit 10.1 FIRST AMENDMENT TO LEASE (Schr?dinger, Inc. ? 1540 Broadway) THIS FIRST AMENDMENT TO LEASE (this ?Amendment?) is dated effective and for identification purposes as of May 19, 2022, and is made by and between SPUSV5 1540 BROADWAY, LLC, a Delaware limited liability company (?Landlord?), and SCHR?DINGER, INC., a Delaware corporation (?Tenant?). RECITALS: WHEREAS, pursuant to the terms of

August 4, 2022 EX-10.7

Form of Restricted Stock Unit Agreement for Non-U.S. Participants under the 2022 Equity Incentive Plan

Exhibit 10.7 Schr?dinger, Inc. RESTRICTED STOCK UNIT AGREEMENT FOR NON-U.S. PARTICIPANTS Schr?dinger, Inc. (the ?Company?) hereby grants the following restricted stock units pursuant to its 2022 Equity Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of recipient (the ?Participant?): Grant Date: Number of restricted stock units (?RSUs?) granted:

August 4, 2022 EX-10.4

Form of Option Agreement for U.S. Participants under the 2022 Equity Incentive Plan

Exhibit 10.4 Schr?dinger, Inc. STOCK OPTION AGREEMENT Schr?dinger, Inc. (the ?Company?) hereby grants the following stock option pursuant to its 2022 Equity Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of optionee (the ?Participant?): Grant Date: Incentive Stock Option or Nonstatutory Stock Option: Number of shares of the Company?s Common St

August 4, 2022 S-8

As filed with the Securities and Exchange Commission on August 4, 2022

S-8 1 sdgr-s8.htm S-8 As filed with the Securities and Exchange Commission on August 4, 2022 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Schrödinger, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or Other Jurisdiction of Incorporation or Organi

August 4, 2022 EX-99.1

Schrödinger Reports Second Quarter 2022 Financial Results Software Revenue of $30.0 Million, a 25 Percent Increase Over Second Quarter of 2021; Total Revenue of $38.5 Million, up 29 Percent Over Second Quarter of 2021 Company Maintains Full-Year 2022

Exhibit 99.1 Schr?dinger Reports Second Quarter 2022 Financial Results Software Revenue of $30.0 Million, a 25 Percent Increase Over Second Quarter of 2021; Total Revenue of $38.5 Million, up 29 Percent Over Second Quarter of 2021 Company Maintains Full-Year 2022 Financial Outlook Phase 1 Clinical Study of SGR-1505, Schr?dinger?s MALT1 Inhibitor, On-Track to Begin in the Fourth Quarter of 2022 New

August 4, 2022 EX-10.5

Form of Option Agreement for Non-U.S. Participants under the 2022 Equity Incentive Plan

Exhibit 10.5 Schr?dinger, Inc. STOCK OPTION AGREEMENT FOR NON-U.S. PARTICIPANTS Schr?dinger, Inc. (the ?Company?) hereby grants the following stock option pursuant to its 2022 Equity Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of optionee (the ?Participant?): Grant Date: Nonstatutory Stock Option: Number of shares of the Company?s Common St

August 4, 2022 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Schr?dinger, Inc.

August 4, 2022 EX-99.1

2021 Inducement Equity Incentive Plan, as amended.

Exhibit 99.1 Schr?dinger, Inc. 2021 INDUCEMENT EQUITY INCENTIVE PLAN 1. Purpose The purpose of this 2021 Inducement Equity Incentive Plan (the ?Plan?) of Schr?dinger, Inc., a Delaware corporation (the ?Company?), is to advance the interests of the Company?s stockholders by enhancing the Company?s ability to attract, retain and motivate persons who are expected to make important contributions to th

August 4, 2022 EX-10.6

Form of Restricted Stock Unit Agreement for U.S. Participants under the 2022 Equity Incentive Plan

Exhibit 10.6 Schr?dinger, Inc. RESTRICTED STOCK UNIT AGREEMENT Schr?dinger, Inc. (the ?Company?) hereby grants the following restricted stock units pursuant to its 2022 Equity Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of recipient (the ?Participant?): Grant Date: Number of restricted stock units (?RSUs?) granted: Number, if any, of RSUs t

June 17, 2022 S-8

As filed with the Securities and Exchange Commission on June 17, 2022

As filed with the Securities and Exchange Commission on June 17, 2022 Registration No.

June 17, 2022 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Schr?dinger, Inc.

June 16, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 15, 2022 Schrödinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization) (Co

June 16, 2022 EX-99.1

SCHRÖDINGER, INC. 2022 EQUITY INCENTIVE PLAN

Exhibit 99.1 SCHR?DINGER, INC. 2022 EQUITY INCENTIVE PLAN 1. Purpose The purpose of this 2022 Equity Incentive Plan (the ?Plan?) of Schr?dinger, Inc., a Delaware corporation (the ?Company?), is to advance the interests of the Company?s stockholders by enhancing the Company?s ability to attract, retain and motivate persons who are expected to make important contributions to the Company and by provi

June 9, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEFA14A 1 d297165ddefa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as

May 19, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

May 19, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 17, 2022 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or other jurisdiction of incorporation or organization) 001-39206 (Com

May 4, 2022 EX-99.1

Schrödinger Reports First Quarter 2022 Financial Results Software Revenue of $33.1 Million, a 26 Percent Increase Over First Quarter of 2021; Total Revenue of $48.7 Million, up 51 Percent Over First Quarter of 2021 Company Maintains Full-Year 2022 Fi

Exhibit 99.1 Schr?dinger Reports First Quarter 2022 Financial Results Software Revenue of $33.1 Million, a 26 Percent Increase Over First Quarter of 2021; Total Revenue of $48.7 Million, up 51 Percent Over First Quarter of 2021 Company Maintains Full-Year 2022 Financial Outlook Internal Pipeline Progressing, With IND Submission for SGR-1505, Schr?dinger?s MALT1 Inhibitor, On-Track for First Half o

May 4, 2022 EX-10.3

Third Amended and Restated Director Compensation Policy

EXHIBIT 10.3 Schr?dinger, Inc. Third Amended and Restated Director Compensation Policy Adopted on March 15, 2022 Effective as of January 1, 2022, the non-employee directors of Schr?dinger, Inc. (the ?Company?) shall receive the following compensation for their service as members of the Board of Directors (the ?Board?) of the Company. Director Compensation Our goal is to provide compensation for ou

May 4, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 4, 2022 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or other jurisdiction of incorporation or organization) 001-39206 (Comm

May 4, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

April 29, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEFA14A 1 sdgr-defa14a20220615.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only

April 28, 2022 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEF 14A 1 sdgr-def14a20220615.htm DEF 14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only

April 28, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEFA14A 1 sdgr-defa14a20220428.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only

March 2, 2022 EX-10.2

Consulting Agreement, dated as of February 28, 2022, by and between Schrödinger, Inc. and Joel Lebowitz.

Exhibit 10.2 CONSULTING AGREEMENT This Consulting Agreement (this ?Agreement?) is entered into as of the Separation Date by and between Schr?dinger, Inc. (the ?Company?), and Joel Lebowitz (the ?Consultant?), and will be effective as of the day immediately following the Separation Date (hereinafter, the ?Consulting Effective Date?). Capitalized terms used but not defined herein have the meanings s

March 2, 2022 EX-10.1

Transition, Separation and Release of Claims Agreement, dated as of February 28, 2022, by and between Schrödinger, Inc. and Joel Lebowitz.

Exhibit 10.1 TRANSITION, SEPARATION AND RELEASE OF CLAIMS AGREEMENT This Transition, Separation and Release of Claims Agreement (the ?Agreement?) is entered into by and between Schr?dinger, Inc. (the ?Company?) and Joel Lebowitz (?Executive?) (together, the ?Parties?). WHEREAS, the Company and Executive are parties to the Employment Agreement dated as of November 14, 2018 (the ?Employment Agreemen

March 2, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 28, 2022 Schr?dinger, Inc. (Exact name of registrant as specified in its charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation) (Commission Fil

February 24, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number 001-39206 Schrodinger, In

February 24, 2022 S-8

As filed with the Securities and Exchange Commission on February 24, 2022

As filed with the Securities and Exchange Commission on February 24, 2022 Registration No.

February 24, 2022 EX-21.1

Subsidiaries of the Registrant

Exhibit 21.1 List of Subsidiaries Name Jurisdiction of Incorporation Schr?dinger, LLC Delaware Schr?dinger GmbH Germany Synaptic Science LLC Delaware Schr?dinger, KK Japan Reo Discovery Limited Ireland Faxian Therapeutics, LLC Delaware Schr?dinger Technologies Ltd United Kingdom Schr?dinger India Private Limited India Schrodinger Korea LLC South Korea XTAL BioStructures, Inc. Massachusetts

February 24, 2022 EX-10.5

Form of Stock Option Agreement and Form of Restricted Stock Unit Agreement for U.S. Participants under the 2020 Equity Incentive Plan

Exhibit 10.5 Schr?dinger, Inc. STOCK OPTION AGREEMENT Schr?dinger, Inc. (the ?Company?) hereby grants the following stock option pursuant to its 2020 Equity Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of optionee (the ?Participant?): Grant Date: Incentive Stock Option or Nonstatutory Stock Option: Number of shares of the Company?s Common St

February 24, 2022 EX-10.6

Form of Restricted Stock Unit Agreement for Non-U.S. Participants under the 2020 Equity Incentive Plan

Exhibit 10.6 Schr?dinger, Inc. Restricted Stock Unit Agreement FOR NON-U.S. PARTICIPANTS Schr?dinger, Inc. (the ?Company?) hereby grants the following restricted stock units pursuant to its 2020 Equity Incentive Plan. The terms and conditions attached hereto are also a part thereof. Notice of Grant Name of recipient (the ?Participant?): Grant Date: Number of restricted stock units (?RSUs?) granted

February 24, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 24, 2022 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or other jurisdiction of incorporation or organization) 001-39206

February 24, 2022 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Schr?dinger, Inc.

February 24, 2022 EX-99.1

Schrödinger Reports Financial Results for the Fourth Quarter and Full Year 2021 Delivered Strong Fourth Quarter, with Software Revenue of $38.6 Million, a 55 Percent Increase over Fourth Quarter of 2020 Full Year 2021 Total Revenue of $137.9 Million,

Exhibit 99.1 Schr?dinger Reports Financial Results for the Fourth Quarter and Full Year 2021 Delivered Strong Fourth Quarter, with Software Revenue of $38.6 Million, a 55 Percent Increase over Fourth Quarter of 2020 Full Year 2021 Total Revenue of $137.9 Million, up 28 Percent Year-over-Year, with Full Year 2021 Software Revenue of $113.2 Million, up 22 Percent Year-over-Year Provides Financial Ou

February 10, 2022 SC 13G/A

SDGR / Schrodinger Inc / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv01845-schrodingerincunited.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 1)* Name of issuer: Schrodinger Inc./United States Title of Class of Securities: Common Stock CUSIP Number: 80810D103 Date of Event Which Requires Filing of this Statement: December 31, 2021 Check the appropriate

December 21, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 16, 2021 Schrödinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization)

December 1, 2021 SC 13G/A

SDGR / Schrodinger Inc / SHAW DAVID E - SCHEDULE 13G, AMENDMENT NO. 2 Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Schr?dinger, Inc. (Name of Issuer) Common Stock, par value $0.01 per share (Title of Class of Securities) 80810D103 (CUSIP Number) December 1, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pu

November 10, 2021 EX-99.1

Schrödinger Reports Third Quarter 2021 Financial Results and Provides Company Update Third Quarter Total Revenue of $29.9 Million, Up 16 Percent Year-Over-Year; Software Revenue of $24.3 Million Recent Collaboration with Centessa Pharmaceuticals Subs

EX-99.1 2 sdgr-ex9916.htm EX-99.1 Exhibit 99.1 Schrödinger Reports Third Quarter 2021 Financial Results and Provides Company Update Third Quarter Total Revenue of $29.9 Million, Up 16 Percent Year-Over-Year; Software Revenue of $24.3 Million Recent Collaboration with Centessa Pharmaceuticals Subsidiary, Orexia Therapeutics, Highlights Continued Large-Scale Adoption of Platform by Biotechnology Com

November 10, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2021 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or other jurisdiction of incorporation or organization) 001-39206

November 10, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

August 12, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2021 Schrodinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or other jurisdiction of incorporation or organization) 001-39206 (

August 12, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

August 12, 2021 EX-99

Schrödinger Reports Second Quarter 2021 Financial Results and Provides Company Update Second Quarter Total Revenue of $29.8 Million, Up 29 Percent Year-Over-Year; Software Revenue of $24.1 Million, Up 15 Percent Year-Over-Year; Company Maintains Full

EX-99 2 FINAL-sdgr-ex9916.htm EX-99.1 Exhibit 99.1 Schrödinger Reports Second Quarter 2021 Financial Results and Provides Company Update Second Quarter Total Revenue of $29.8 Million, Up 29 Percent Year-Over-Year; Software Revenue of $24.1 Million, Up 15 Percent Year-Over-Year; Company Maintains Full-Year 2021 Financial Outlook New Drug Discovery, Co-Development and Co-Commercialization Oncology C

August 12, 2021 EX-10.3

Amended and Restated Executive Severance and Change in Control Benefits Plan

Exhibit 10.3 Schr?dinger, Inc. Amended and Restated Executive Severance and Change in Control Benefits Plan 1.Establishment of Plan. Schr?dinger, Inc., a Delaware corporation, hereby establishes an unfunded severance benefits plan (the ?Plan?) that is intended to be a welfare benefit plan within the meaning of Section 3(1) of ERISA. The Plan is in effect for Covered Employees who experience a Cove

August 12, 2021 EX-10.2

Office Lease Amendment, dated May 6, 2021, by and between Registrant and MADISON-OFC ONE MAIN PLACE OR LLC

EX-10.2 2 sdgr-ex10215.htm EX-10.2 Exhibit 10.2 THIRD AMENDMENT TO OFFICE LEASE This Third Amendment to Office Lease (this "Third Amendment") is made and entered into by and between MADISON-OFC ONE MAIN PLACE OR LLC, a Delaware limited liability company ("Landlord"), and SCHRODINGER, INC., a Delaware corporation ("Tenant"), and will be effective as of the date that Landlord executes this Third Ame

August 12, 2021 EX-10.4

Consultant Agreement, dated July 1, 1999, between the Registrant and Richard A. Friesner, as amended

EX-10.4 4 sdgr-ex10414.htm EX-10.4 Exhibit 10.4 CONSULTANT AGREEMENT AGREEMENT made as of the 1st day of July, 1999 between SCHRÖDINGER, INC., having its place of business at 1500 SW First Avenue, Suite 1180, Portland, Oregon 97201-5881 (“Company”) and RICHARD A. FRIESNER, residing at [**] (“Consultant”). RECITALS A. Company is engaged in the business of designing, developing, distributing, sellin

June 21, 2021 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 17, 2021 Schr?dinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or other jurisdiction of incorporation or organization) 001-39206 (Co

May 11, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 11, 2021 Schr?dinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or other jurisdiction of incorporation or organization) 001-39206 (Com

May 11, 2021 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

May 11, 2021 EX-99.1

Schrödinger Reports First Quarter 2021 Financial Results and Provides Company Update First quarter total revenue of $32.1 million, up 23 percent year-over-year; Software revenue of $26.3 million, up 11 percent year-over-year Expanded agreement with A

EX-99.1 2 sdgr-ex9916.htm EX-99.1 Exhibit 99.1 Schrödinger Reports First Quarter 2021 Financial Results and Provides Company Update First quarter total revenue of $32.1 million, up 23 percent year-over-year; Software revenue of $26.3 million, up 11 percent year-over-year Expanded agreement with AstraZeneca; New agreement with NVIDIA Development candidate selected for MALT1 inhibitor program; Inter

April 28, 2021 DEF 14A

- DEF 14A

DEF 14A 1 sdgr-def14a20210617.htm DEF 14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only

April 28, 2021 DEFA14A

- DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

April 26, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Schrödinger, Inc. (Name of Issuer) Common Stock, par value $0.01 per share (Title of Class of Securities) 80810D103 (CUSIP Number) December 31, 2020 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule p

April 26, 2021 EX-99.1

JOINT FILING AGREEMENT

Exhibit 99.1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, each of the undersigned Reporting Persons hereby agrees to the joint filing, along with all other such Reporting Persons, on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the common stock, $0.01 par value, of Schröding

April 8, 2021 EX-10.1

Office Lease Agreement, dated April 5, 2021, by and between the Registrant and SPUSV5 1540 Broadway, LLC

EX-10.1 2 sdgr-ex1016.htm EX-10.1 Exhibit 10.1 OFFICE LEASE by and between SPUSV5 1540 BROADWAY, LLC, a Delaware limited liability company, as Landlord and Schrödinger, Inc., a Delaware corporation, as Tenant, Premises: 1540 Broadway Suites 2100, 2200, 2300 and 2400 New York, NY 10036 TABLE OF CONTENTS ARTICLE 1. - BASIC LEASE PROVISIONS3 ARTICLE 2. - DEMISE; TERM; USE; COMPLIANCE7 ARTICLE 3. - CO

April 8, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

8-K 1 sdgr-8k20210405.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 5, 2021 Schrödinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or other jurisdiction of incorporation

March 23, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 23, 2021 Schr?dinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or organization) (C

March 23, 2021 EX-99.1

Transforming Discovery of Therapeutics and Materials March 23, 2021

EX-99.1 Exhibit 99.1 Transforming Discovery of Therapeutics and Materials March 23, 2021 Cautionary Note and Disclaimer This presentation contains certain “forward-looking statements” within the meaning of the U.S. Private Securities Litigation Reform Act of 1995 that involve substantial risks and uncertainties. All statements, other than statements of historical fact, contained in this presentati

March 4, 2021 EX-4.6

Form of Subordinated Note

EX-4.6 5 d113429dex46.htm EX-4.6 Exhibit 4.6 Form of Subordinated Note (FACE OF SECURITY) [Each Global Security shall bear substantially the following legend: UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE REGISTERED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO T

March 4, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 4, 2021 Schr?dinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or other jurisdiction of incorporation or organization) 001-39206 (Co

March 4, 2021 S-8

- FORM S-8

S-8 1 d123168ds8.htm FORM S-8 As filed with the Securities and Exchange Commission on March 4, 2021 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Schrödinger, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or Other Jurisdiction of Incorporation or

March 4, 2021 EX-99.2

2021 Inducement Equity Incentive Plan.

Exhibit 99.2 Schr?dinger, Inc. 2021 INDUCEMENT EQUITY INCENTIVE PLAN 1. Purpose The purpose of this 2021 Inducement Equity Incentive Plan (the ?Plan?) of Schr?dinger, Inc., a Delaware corporation (the ?Company?), is to advance the interests of the Company?s stockholders by enhancing the Company?s ability to attract, retain and motivate persons who are expected to make important contributions to th

March 4, 2021 EX-4.5

Form of Senior Note

EX-4.5 4 d113429dex45.htm EX-4.5 Exhibit 4.5 Form of Senior Note (FACE OF SECURITY) [Each Global Security shall bear substantially the following legend: UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE REGISTERED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEP

March 4, 2021 EX-4.3

Exhibit 4.3

EX-4.3 2 sdgr-ex43186.htm EX-4.3 Exhibit 4.3 DESCRIPTION OF SECURITIES REGISTERED UNDER SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED The following description of the securities of Schrödinger, Inc. (“us,” “our,” “we” or the “Company”) registered under Section 12 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), is intended as a summary only and therefore is

March 4, 2021 EX-10.41

Restricted Stock Unit Agreement for Non-U.S. Participants under 2021 Inducement Equity Incentive Plan

EX-10.41 8 sdgr-ex1041366.htm EX-10.41 EXHIBIT 10.41 Schrödinger, Inc. Restricted Stock Unit Agreement FOR NON-U.S. PARTICIPANTS Granted under 2021 Inducement Equity Incentive Plan Schrödinger, Inc. (the “Company”) hereby grants the following restricted stock units pursuant to its 2021 Inducement Equity Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Gran

March 4, 2021 EX-10.37

Collaboration and License Agreement, dated November 22, 2020, by and between the Registrant and Bristol-Myers Squibb Company

EX-10.37 4 sdgr-ex1037103.htm EX-10.37 CONFIDENTIAL Execution Version Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Triple asterisks denote omissions. EXHIBIT 10.37 COLLABORATION AND LICENSE AGREEMENT This Collaboration and License Agreement (this “Agreement”)

March 4, 2021 EX-10.38

2021 Inducement Equity Incentive Plan

EX-10.38 5 sdgr-ex1038367.htm EX-10.38 EXHIBIT 10.38 Schrödinger, Inc. 2021 INDUCEMENT EQUITY INCENTIVE PLAN 1. Purpose The purpose of this 2021 Inducement Equity Incentive Plan (the “Plan”) of Schrödinger, Inc., a Delaware corporation (the “Company”), is to advance the interests of the Company’s stockholders by enhancing the Company’s ability to attract, retain and motivate persons who are expect

March 4, 2021 EX-10.40

Restricted Stock Unit Agreement for U.S. Participants under 2021 Inducement Equity Incentive Plan

EX-10.40 7 sdgr-ex1040365.htm EX-10.40 EXHIBIT 10.40 Schrödinger, Inc. RESTRICTED STOCK UNIT AGREEMENT Granted under 2021 Inducement Equity Incentive Plan Schrödinger, Inc. (the “Company”) hereby grants the following restricted stock units pursuant to its 2021 Inducement Equity Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of recipient (the “

March 4, 2021 EX-4.3

Form of Senior Indenture

EX-4.3 2 d113429dex43.htm EX-4.3 Exhibit 4.3 SCHRÖDINGER, INC. and Trustee INDENTURE Dated as of SENIOR DEBT SECURITIES CROSS-REFERENCE TABLE1 Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 6.09 310(b) 6.08 6.10 310(c) Inapplicable 311(a) 6.13 311(b) 6.13 311(c) Inapplicable 312(a) 4.01 4.04 312(b) 4.04(c) 312(c) 4.04(c) 313(a) 4.03 313(b) 4.03 313(c) 4.03 313(d) 4.

March 4, 2021 EX-10.7

Second Amended and Restated Director Compensation Policy

EXHIBIT 10.7 Schr?dinger, Inc. Second Amended and Restated Director Compensation Policy Adopted on February 18, 2021 Effective as of January 1, 2021, the non-employee directors of Schr?dinger, Inc. (the ?Company?) shall receive the following compensation for their service as members of the Board of Directors (the ?Board?) of the Company. Director Compensation Our goal is to provide compensation fo

March 4, 2021 S-3ASR

- S-3ASR

Table of Contents As filed with the Securities and Exchange Commission on March 4, 2021 Registration No.

March 4, 2021 EX-99.1

Schrödinger Reports Financial Results for the Fourth Quarter and Full Year 2020 and Provides Outlook for 2021 Total revenue of $108.1 million in 2020, up 26 percent year-over-year Software revenue of $92.5 million in 2020, up 39 percent year-over-yea

Exhibit 99.1 Schrödinger Reports Financial Results for the Fourth Quarter and Full Year 2020 and Provides Outlook for 2021 Total revenue of $108.1 million in 2020, up 26 percent year-over-year Software revenue of $92.5 million in 2020, up 39 percent year-over-year Strong financial position enables continued investment in advancing the science underlying Schrödinger’s computational platform Interna

March 4, 2021 EX-10.39

Nonstatutory Stock Option Agreement under 2021 Inducement Equity Incentive Plan

EX-10.39 6 sdgr-ex1039368.htm EX-10.39 EXHIBIT 10.39 Schrödinger, Inc. NONSTATUTORY STOCK OPTION AGREEMENT Granted under 2021 Inducement Equity Incentive Plan Schrödinger, Inc. (the “Company”) hereby grants the following stock option pursuant to its 2021 Inducement Equity Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of optionee (the “Partici

March 4, 2021 EX-4.4

Form of Subordinated Indenture

EX-4.4 3 d113429dex44.htm EX-4.4 Exhibit 4.4 SCHRÖDINGER, INC. and Trustee INDENTURE Dated as of SUBORDINATED DEBT SECURITIES CROSS-REFERENCE TABLE 1 Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 6.09 310(b) 6.08 6.10 310(c) Inapplicable 311(a) 6.13 311(b) 6.13 311(c) Inapplicable 312(a) 4.01 4.04 312(b) 4.04(c) 312(c) 4.04(c) 313(a) 4.03 313(b) 4.03 313(c) 4.03 31

March 4, 2021 10-K

Annual Report - 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2020 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number 001-39206 Schrodinger, In

February 12, 2021 SC 13G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Schrödinger, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Schr?dinger, Inc. (Name of Issuer) Common Stock, $0.01 par value (Title of Class of Securities) 80810D103 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to

February 10, 2021 SC 13G

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 Name of issuer: Schrodinger Inc./United States Title of Class of Securities: Common Stock CUSIP Number: 80810D103 Date of Event Which Requires Filing of this Statement: December 31, 2020 Check the appropriate box to designate the rule pursuant to which this Schedule is filed: ☒ Rule 13d

January 19, 2021 SC 13G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. ________)*

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Schrödinger, Inc. (Name of Issuer) Common Stock, par value $0.01 per share (Title of Class of Securities) 80810D103 (CUSIP Number) December 31, 2020 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pu

November 23, 2020 8-K

Entry into a Material Definitive Agreement - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 22, 2020 Schrödinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 001-39206 95-4284541 (State or other jurisdiction of incorporation or orga

November 12, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2020 Schrödinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or other jurisdiction of incorporation or organization) 001-39206

November 12, 2020 EX-99.1

Schrödinger, Inc. Reports Third Quarter 2020 Financial Results and Business Update Total revenue of $25.8 million, up 29% year-over-year; Software revenue of $22.9 million, up 42% year-over-year Raised $325.6 million net proceeds in equity financing

Exhibit 99.1 Schrödinger, Inc. Reports Third Quarter 2020 Financial Results and Business Update Total revenue of $25.8 million, up 29% year-over-year; Software revenue of $22.9 million, up 42% year-over-year Raised $325.6 million net proceeds in equity financing Presenting data on our MALT 1 inhibitor program at the American Society of Hematology (ASH) Annual Meeting & Exposition Conference call t

November 12, 2020 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2020 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

November 12, 2020 EX-10.2

Form of Stock Option Agreement for Non-U.S. Participants under the 2020 Equity Incentive Plan

EX-10.2 3 sdgr-ex1028.htm EX-10.2 Exhibit 10.2 Schrödinger, Inc. STOCK OPTION AGREEMENT FOR NON-U.S. PARTICIPANTS Schrödinger, Inc. (the “Company”) hereby grants the following stock option pursuant to its 2020 Equity Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of optionee (the “Participant”): Grant Date: Nonstatutory Stock Option: Number of

November 12, 2020 EX-10.1

Restricted Stock Unit Agreement for Non-U.S. Participants under the 2020 Equity Incentive Plan

Exhibit 10.1 Schrödinger, Inc. Restricted Stock Unit Agreement FOR NON-U.S. PARTICIPANTS Schrödinger, Inc. (the “Company”) hereby grants the following restricted stock units pursuant to its 2020 Equity Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of recipient (the “Participant”): Grant Date: Number of restricted stock units (“RSUs”) granted:

August 13, 2020 424B4

5,000,000 Shares Common Stock

424B4 Table of Contents Filed Pursuant to Rule 424(b)(4) Registration No. 333-243714 Registration No. 333-245169 PROSPECTUS 5,000,000 Shares Common Stock We are offering 4,500,000 shares of our common stock, and the selling stockholder identified in this prospectus is offering 500,000 shares of our common stock. We will not receive any proceeds from the sale of shares of our common stock by the se

August 12, 2020 S-1MEF

- S-1MEF

S-1MEF As filed with the Securities and Exchange Commission on August 12, 2020. Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SCHRÖDINGER, INC. (Exact name of registrant as specified in its charter) Delaware 2834 95-4284541 (State or other jurisdiction of incorporation or organization)

August 10, 2020 S-1

Power of Attorney (incorporated by reference to the signature page to the Registrant’s Registration Statement on Form S-1 (File No. 333-243714) filed with the Commission on August 10, 2020)

S-1 Table of Contents As filed with the Securities and Exchange Commission on August 10, 2020.

August 10, 2020 CORRESP

-

CORRESP August 10, 2020 United States Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.

August 10, 2020 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2020 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

August 10, 2020 CORRESP

-

CORRESP Schrödinger, Inc. 120 West 45th Street, 17th Floor New York, New York 10036 August 10, 2020 VIA EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: Schrödinger, Inc. Registration Statement on Form S-1 Request for Acceleration Ladies and Gentlemen: Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended

August 10, 2020 EX-10.2

Independent Contractor Agreement, dated June 23, 2020, by and between the Registrant and Gates Ventures, LLC

Execution Copy Exhibit 10.2 Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. INDEPENDENT CONTRACTOR AGREEMENT This INDEPENDENT CONTRACTOR AGREEMENT (the “Agreement”) is entered into by and between Gates Ventures, LLC (“Company”)

August 10, 2020 EX-99.1

Schrödinger, Inc. Reports Second Quarter 2020 Financial Results and Business Updates Total revenue of $23.1 million, up 21% year-over-year Software revenue of $20.9 million, up 44% year-over-year New strategic agreements with Thermo Fisher and Viva B

Exhibit 99.1 Schrödinger, Inc. Reports Second Quarter 2020 Financial Results and Business Updates Total revenue of $23.1 million, up 21% year-over-year Software revenue of $20.9 million, up 44% year-over-year New strategic agreements with Thermo Fisher and Viva Biotech Rapid progress across internal pipeline; three programs in late-stage discovery Conference call today, Monday, August 10, 2020 at

August 10, 2020 EX-10.1

Consultant Agreement, dated July 1, 1999, between the Registrant and Richard A. Friesner, as amended

Exhibit 10.1 CONSULTANT AGREEMENT AGREEMENT made as of the 1st day of July, 1999 between SCHRÖDINGER, INC., having its place of business at 1500 SW First Avenue, Suite 1180, Portland, Oregon 97201-5881 (“Company”) and RICHARD A. FRIESNER, residing at [**] (“Consultant”). RECITALS A. Company is engaged in the business of designing, developing, distributing, selling, licensing, leasing and servicing

August 10, 2020 EX-1.1

Form of Underwriting Agreement

EX-1.1 Exhibit 1.1 [●] Shares SCHRÖDINGER, INC. COMMON STOCK (PAR VALUE $0.01 PER SHARE) UNDERWRITING AGREEMENT [August] [●], 2020 [August] [●], 2020 Morgan Stanley & Co. LLC BofA Securities, Inc. Jefferies LLC BMO Capital Markets Corp. As Representatives of the several Underwriters named in Schedule II hereto c/o Morgan Stanley & Co. LLC 1585 Broadway New York, New York 10036 c/o BofA Securities,

August 10, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 10, 2020 Schrödinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or other jurisdiction of incorporation or organization) 001-39206 (

July 31, 2020 DRS

-

DRS Table of Contents Confidential Treatment Requested by Schrödinger, Inc. Confidential Treatment Requested by Schrödinger, Inc. Pursuant to 17 C.F.R. § 200.83 As confidentially submitted to the Securities and Exchange Commission on July 30, 2020. This draft registration statement has not been publicly filed with the Securities and Exchange Commission and all information herein remains strictly c

June 12, 2020 EX-99.1

Transforming Discovery of Therapeutics and Materials

EX-99.1 Exhibit 99.1 SCHRÖDINGER Transforming Discovery of Therapeutics and Materials Cautionary Note and Disclaimer This presentation contains certain “forward-looking statements” within the meaning of the U.S. Private Securities Litigation Reform Act of 1995 that involve substantial risks and uncertainties. All statements, other than statements of historical fact, contained in this presentation,

June 12, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 12, 2020 Schrödinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or other jurisdiction of incorporation or organization) 001-

May 13, 2020 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2020 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39206 Schrodinger, Inc.

May 13, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 13, 2020 Schrödinger, Inc. (Exact name of Registrant as Specified in Its Charter) Delaware 95-4284541 (State or other jurisdiction of incorporation or organization) 001-39206

May 13, 2020 EX-99.1

Schrödinger Reports First Quarter 2020 Financial Results and Recent Business Updates Total revenue of $26.2 million and strong growth of 26% year-over-year Record software revenue of $23.8 million, up 28% year-over-year Raised $209.6 million in net p

EX-99.1 Exhibit 99.1 Schrödinger Reports First Quarter 2020 Financial Results and Recent Business Updates Total revenue of $26.2 million and strong growth of 26% year-over-year Record software revenue of $23.8 million, up 28% year-over-year Raised $209.6 million in net proceeds through initial public offering Conference call today, Wednesday, May 13, 2020 at 8:30 a.m. ET NEW YORK – May 13, 2020 -

May 4, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 30, 2020 Schrödinger, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-39206 95-4284541 (State or Other Jurisdiction of Incorporation) (Commission File N

March 16, 2020 EX-4.3

Description of Securities Registered Under Section 12 of the Exchange Act

Exhibit 4.3 DESCRIPTION OF SECURITIES REGISTERED UNDER SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED The following description of the securities of Schrödinger, Inc. (“us,” “our,” “we” or the “Company”) registered under Section 12 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), is intended as a summary only and therefore is not a complete description of our

March 16, 2020 10-K

SDGR / Schrodinger, Inc. 10-K - Annual Report - 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2019 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number 001-39206 Schrödinger, In

February 10, 2020 EX-3.2

Amended and Restated Bylaws

EX-3.2 Exhibit 3.2 AMENDED AND RESTATED BYLAWS OF SCHRÖDINGER, INC. TABLE OF CONTENTS Page ARTICLE I. STOCKHOLDERS 1 1.1 Place of Meetings 1 1.2 Annual Meeting 1 1.3 Special Meetings 1 1.4 Record Date for Stockholder Meetings 4 1.5 Notice of Meetings 5 1.6 Voting List 5 1.7 Quorum 6 1.8 Adjournments 6 1.9 Voting and Proxies 7 1.10 Action at Meeting 7 1.11 Nomination of Directors 8 1.12 Notice of O

February 10, 2020 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 10, 2020 Schrödinger, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-39206 95-4284541 (State or Other Jurisdiction of Incorporation) (Commissio

February 10, 2020 SC 13G

SDGR / Schrodinger, Inc. / Flynn James E Passive Investment

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No.

February 10, 2020 EX-3.1

Restated Certificate of Incorporation

EX-3.1 Exhibit 3.1 RESTATED CERTIFICATE OF INCORPORATION OF SCHRÖDINGER, INC. Schrödinger, Inc., a corporation organized and existing under the General Corporation Law of the State of Delaware, does hereby certify that the name of the corporation is Schrödinger, Inc. and the original certificate of incorporation of the corporation was filed with the Secretary of State of the State of Delaware on M

February 6, 2020 424B4

11,882,352 Shares Common Stock

424B4 Table of Contents PROSPECTUS Filed Pursuant to Rule 424(b)(4) Registration No.

February 6, 2020 S-8

SDGR / Schrodinger, Inc. S-8 - - S-8

S-8 As filed with the Securities and Exchange Commission on February 6, 2020 Registration No.

February 6, 2020 EX-4.1

Amended and Restated Certificate of Incorporation, as amended, of the Registrant

EX-4.1 Exhibit 4.1 AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF SCHRÖDINGER, INC. (Pursuant to Sections 242 and 245 of the General Corporation Law of the State of Delaware) Schrödinger, Inc., a corporation organized and existing under and by virtue of the provisions of the General Corporation Law of the State of Delaware (the “General Corporation Law”), DOES HEREBY CERTIFY: 1. That the nam

February 5, 2020 S-1MEF

As filed with the Securities and Exchange Commission on February 5, 2020.

As filed with the Securities and Exchange Commission on February 5, 2020. Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SCHR?DINGER, INC. (Exact name of registrant as specified in its charter) Delaware 2834 95-4284541 (State or other jurisdiction of incorporation or organization) (Prima

February 3, 2020 CORRESP

SDGR / Schrodinger, Inc. CORRESP - -

CORRESP February 3, 2020 United States Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.

February 3, 2020 CORRESP

SDGR / Schrodinger, Inc. CORRESP - -

CORRESP Schrödinger, Inc. 120 West 45th Street, 17th Floor New York, New York 10036 February 3, 2020 VIA EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: Schrödinger, Inc. Registration Statement on Form S-1 File No. 333-235890 Request for Acceleration Ladies and Gentlemen: Pursuant to Rule 461 promulgated under the Securities Ac

January 31, 2020 8-A12B

Form 8-A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-A FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 Schr?dinger, Inc. (Exact name of registrant as specified in its charter) Delaware 95-4284541 (State or other jurisdiction of incorporation or organization) (I.R.S. Employer Identification No.) 120

January 27, 2020 EX-3.3

Form of Restated Certificate of Incorporation of the Registrant (to be effective upon the closing of the Registrant’s initial public offering) (incorporated by reference to Exhibit 3.3 to Amendment No. 1 to the Registrant’s Registration Statement on Form S-1 (File No. 333-235890) filed with the Securities and Exchange Commission on January 27, 2020).

Exhibit 3.3 RESTATED CERTIFICATE OF INCORPORATION OF SCHR?DINGER, INC. (originally incorporated on May 22, 1995) FIRST: The name of the Corporation is Schr?dinger, Inc. SECOND: The address of the Corporation?s registered office in the State of Delaware is 1209 Orange Street, in the City of Wilmington, County of New Castle, 19801. The name of its registered agent at that address is The Corporation

January 27, 2020 EX-3.2

Amended and Restated Bylaws, as amended, of the Registrant

Exhibit 3.2 AMENDED AND RESTATED BYLAWS OF SCHR?DINGER, INC. (a Delaware corporation) Adopted: November 9, 2018 TABLE OF CONTENTS Page ARTICLE I STOCKHOLDERS 1 1.1 Place of Meetings 1 1.2 Annual Meeting 1 1.3 Special Meetings 1 1.4 Notice of Meetings 1 1.5 Voting List 1 1.6 Quorum 2 1.7 Adjournments 2 1.8 Voting and Proxies 2 1.9 Action at Meeting 3 1.10 Conduct of Meetings 3 1.11 Action without M

January 27, 2020 EX-10.5

Form of Stock Option Agreement and Form of Restricted Stock Unit Agreement under the 2020 Equity Incentive Plan

Exhibit 10.5 Schr?dinger, Inc. STOCK OPTION AGREEMENT Schr?dinger, Inc. (the ?Company?) hereby grants the following stock option pursuant to its 2020 Equity Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of optionee (the ?Participant?): Grant Date: Incentive Stock Option or Nonstatutory Stock Option: Number of shares of the Company?s Common St

January 27, 2020 EX-1.1

Form of Underwriting Agreement

EX-1.1 2 d766269dex11.htm EX-1.1 Exhibit 1.1 [●] Shares SCHRÖDINGER, INC. COMMON STOCK (PAR VALUE $0.01 PER SHARE) UNDERWRITING AGREEMENT [•], 2020 [●], 2020 Morgan Stanley & Co. LLC BofA Securities, Inc. Jefferies LLC BMO Capital Markets Corp. As Representatives of the several Underwriters named in Schedule I hereto c/o Morgan Stanley & Co. LLC 1585 Broadway New York, New York 10036 c/o BofA Secu

January 27, 2020 EX-10.6

2020 Employee Stock Purchase Plan

Exhibit 10.6 Schr?dinger, Inc. 2020 EMPLOYEE STOCK PURCHASE PLAN The purpose of this 2020 Employee Stock Purchase Plan (this ?Plan?) is to provide eligible employees of Schr?dinger, Inc. (the ?Company?) and certain of its subsidiaries with opportunities to purchase shares of the Company?s common stock, $0.01 par value per share (the ?Common Stock?), commencing at such time and on such dates as the

January 27, 2020 S-1/A

As filed with the Securities and Exchange Commission on January 27, 2020.

Table of Contents As filed with the Securities and Exchange Commission on January 27, 2020.

January 27, 2020 EX-3.4

Form of Amended and Restated Bylaws of the Registrant (to be effective upon the closing of the Registrant’s initial public offering) (incorporated by reference to Exhibit 3.4 to Amendment No. 1 to the Registrant’s Registration Statement on Form S-1 (File No. 333-235890) filed with the Securities and Exchange Commission on January 27, 2020).

Exhibit 3.4 AMENDED AND RESTATED BYLAWS OF SCHR?DINGER, INC. TABLE OF CONTENTS Page ARTICLE I. STOCKHOLDERS 1 1.1 Place of Meetings 1 1.2 Annual Meeting 1 1.3 Special Meetings 1 1.4 Record Date for Stockholder Meetings 4 1.5 Notice of Meetings 5 1.6 Voting List 5 1.7 Quorum 6 1.8 Adjournments 6 1.9 Voting and Proxies 7 1.10 Action at Meeting 7 1.11 Nomination of Directors 8 1.12 Notice of Other Bu

January 27, 2020 EX-3.5

Certificate of Amendment of Amended and Restated Certificate of Incorporation, as amended, of the Registrant

Exhibit 3.5 CERTIFICATE OF AMENDMENT OF AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF SCHR?DINGER, INC. Pursuant to Section 242 of the General Corporation Law of the State of Delaware Schr?dinger, Inc. (the ?Corporation?), a corporation organized and existing under and by virtue of the General Corporation Law of the State of Delaware (the ?DGCL?), does hereby certify as follows: Resolutions

January 27, 2020 EX-10.7

Director Compensation Policy

EX-10.7 14 d766269dex107.htm EX-10.7 Exhibit 10.7 Schrödinger, Inc. Director Compensation Policy Effective upon the completion of the initial public offering (“IPO”) of Schrödinger, Inc., (the “Company”), the Company’s non-employee directors shall receive the following compensation for their service as members of the Board of Directors (the “Board”) of the Company. Director Compensation Our goal i

January 27, 2020 EX-10.4

2020 Equity Incentive Plan

Exhibit 10.4 Schr?dinger, Inc. 2020 EQUITY INCENTIVE PLAN 1. Purpose The purpose of this 2020 Equity Incentive Plan (the ?Plan?) of Schr?dinger, Inc., a Delaware corporation (the ?Company?), is to advance the interests of the Company?s stockholders by enhancing the Company?s ability to attract, retain and motivate persons who are expected to make important contributions to the Company and by provi

January 27, 2020 EX-4.2

Amended and Restated Share Exchange Agreement, dated January 24, 2020, by and between the Registrant and Bill & Melinda Gates Foundation Trust

Exhibit 4.2 AMENDED AND RESTATED SHARE EXCHANGE AGREEMENT This Amended and Restated Share Exchange Agreement (this ?Agreement?) by and between Schr?dinger, Inc., a Delaware corporation (the ?Company?), and the Bill & Melinda Gates Foundation Trust (the ?Trust?) is dated as of the 24th day of January, 2020 and shall be effective as of the Charter Amendment Filing Date (as defined below). Introducti

January 27, 2020 EX-4.1

Specimen Stock Certificate evidencing the shares of common stock

Exhibit 4.1 CUSIP/IDENTIFIER XXXXXX XX X Holder ID XXXXXXXXXX Insurance Value 00.1,000,000 Number of Shares 123456 DTC 12345678901234512345678 PO BOX 505006, Louisville, KY 40233-5006 Certificate Numbers Num/No Denom. Total. MR A SAMPLE 1234567890/1234567890 111 DESIGNATION (IF ANY) 1234567890/1234567890 222 ADD 1 ADD 2 1234567890/1234567890 333 1234567890/1234567890 444 ADD 3 ADD 4 1234567890/123

January 27, 2020 EX-10.33

Global Bonus Plan

Exhibit 10.33 Schr?dinger, Inc. Global Bonus Plan Effective as of January 1, 2019 This Global Bonus Plan, which we will refer to as the plan, of Schr?dinger, Inc. (?Schr?dinger? or the ?Company?) sets forth the terms and conditions under which designated participants may earn a bonus based on Company sales. 1. Qualifying for Bonus The Compensation Committee of the Board of Directors of the Company

January 27, 2020 EX-10.1

Amended and Restated Investors’ Rights Agreement, dated as of November 9, 2018, by and among the Registrant and the other parties thereto, as amended

Exhibit 10.1 SCHR?DINGER, INC. AMENDED AND RESTATED INVESTORS? RIGHTS AGREEMENT TABLE OF CONTENTS Page 1. Definitions 1 2. Registration Rights 6 2.1 Demand Registration 6 2.2 Company Registration 7 2.3 Underwriting Requirements 8 2.4 Obligations of the Company 9 2.5 Furnish Information 10 2.6 Expenses of Registration 11 2.7 Delay of Registration 11 2.8 Indemnification 11 2.9 Reports Under Exchange

January 16, 2020 CORRESP

SDGR / Schrodinger, Inc. CORRESP - -

CORRESP +1 617 526 6000 (t) +1 617 526 5000 (f) CONFIDENTIAL TREATMENT REQUEST UNDER RULE 83 The entity requesting confidential treatment is: Schrödinger, Inc.

January 10, 2020 EX-10.16

Employment Agreement, dated April 27, 2010, by and between the Registrant and Yvonne Tran

Exhibit 10.16 Schr?dinger, Inc. Employment Agreement This Employment Agreement (?Agreement?) is dated April 27, 2010 and effective as of the Employment Commencement Date set forth in Section 1 below (?Effective Date?) by and between Schr?dinger, Inc., a Delaware corporation (?Company?), and Yvonne Tran (?Employee?). WHEREAS, the Company is currently in the business of (i) designing, developing, di

January 10, 2020 EX-10.15

Employment Agreement, dated February 22, 2017, by and between the Registrant and Jennifer Daniel

EX-10.15 14 d766269dex1015.htm EX-10.15 Exhibit 10.15 Schrödinger, Inc. Employment Agreement This Employment Agreement (“Agreement”) is dated February 22, 2017 and effective as of the Employment Commencement Date set forth in Section 1 below (“Effective Date”) by and between Schrödinger, Inc., a Delaware corporation (“Company”), and Jennifer Daniel (“Employee”). WHEREAS, the Company is currently i

January 10, 2020 EX-10.28

Software and Patent License Agreement, dated May 27, 2008, between The Trustees of Columbia University in the City of New York and Schrödinger, LLC

EX-10.28 27 d766269dex1028.htm EX-10.28 Exhibit 10.28 EXECUTED VERSION CONFIDENTIAL Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. SOFTWARE AND PATENT LICENSE AGREEMENT This SOFTWARE AND PATENT LICENSE AGREEMENT, dated May 27,

January 10, 2020 EX-10.29

Services Royalty Amendment, dated November 1, 2008, by and between The Trustees of Columbia University in the City of New York and Schrödinger, LLC

EX-10.29 28 d766269dex1029.htm EX-10.29 Exhibit 10.29 CONFIDENTIAL EXECUTION VERSION Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. SERVICES ROYALTY AMENDMENT This SERVICES ROYALTY AMENDMENT (“Amendment”), effective as of Nove

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