TTOO / T2 Biosystems, Inc. - Документы SEC, Годовой отчет, Доверенное заявление

Т2 Биосистемы, Инк.
US ˙ OTCPK ˙ US89853L3024

Основная статистика
LEI 54930027RQTU9CHLKL88
CIK 1492674
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to T2 Biosystems, Inc.
SEC Filings (Chronological Order)
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April 7, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 18, 2025 T2 BIOSYSTEMS, INC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 18, 2025 T2 BIOSYSTEMS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-36571 20-4827488 (State or Other Jurisdiction of Incorporation) (Commission File

April 1, 2025 NT 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING (Check one):  ☒  Form 10-K ☐ Form 20-F ☐ Form 11-K ☐ Form 10-Q ☐ Form 10-D ☐ Form N-SAR ☐ Form N-CSR For Period Ended: December 31, 2024 ☐

SEC File Number: 001-31326 CUSIP Number: 29014R103 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

February 20, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 20, 2025 T2 BIOSYSTEMS,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 20, 2025 T2 BIOSYSTEMS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-36571 20-4827488 (State or Other Jurisdiction of Incorporation) (Commission F

February 14, 2025 8-K

Costs Associated with Exit or Disposal Activities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 13, 2025 T2 BIOSYSTEMS, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-36571 20-4827488 (State or Other Jurisdiction of Incorporation) (Commission F

February 11, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 10, 2025 T2 BIOSYSTEMS,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 10, 2025 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission F

January 21, 2025 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14

January 17, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 16, 2025 T2 BIOSYSTEMS, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 16, 2025 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fi

January 8, 2025 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14

January 7, 2025 EX-99.1

T2 Biosystems Announces Preliminary Fourth Quarter and Full Year 2024 Financial Results Achieved record fourth quarter and full-year 2024 sepsis product revenues

EX-99.1 Exhibit 99.1 T2 Biosystems Announces Preliminary Fourth Quarter and Full Year 2024 Financial Results Achieved record fourth quarter and full-year 2024 sepsis product revenues LEXINGTON, Mass., January 7, 2024 (GLOBE NEWSWIRE)— T2 Biosystems, Inc. (NASDAQ: TTOO) (the “Company”), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today announced prel

January 7, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 7, 2025 T2 BIOSYSTEMS, IN

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 7, 2025 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fil

January 3, 2025 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 30, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission F

December 13, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 12, 2024 T2 BIOSYSTEMS,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 12, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission F

December 9, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 9, 2024 T2 BIOSYSTEMS, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 9, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fi

December 9, 2024 EX-99.1

T2 Biosystems Announces Plans to License its Proprietary Technology to Expand its Leadership in Direct-From-Whole-Blood Detection of Sepsis-Causing Pathogens Intends to accelerate broad adoption of direct-from-whole-blood diagnostics, generate non-di

Exhibit 99.1 T2 Biosystems Announces Plans to License its Proprietary Technology to Expand its Leadership in Direct-From-Whole-Blood Detection of Sepsis-Causing Pathogens Intends to accelerate broad adoption of direct-from-whole-blood diagnostics, generate non-dilutive capital, and create a new royalty revenue stream LEXINGTON, Mass., December 9, 2024 (GLOBE NEWSWIRE)— T2 Biosystems, Inc. (NASDAQ:

November 20, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Ame

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy S

November 15, 2024 EX-99.2

Trip Taylor, IR

EX-99.2 Exhibit 99.2 Trip Taylor, IR Thank you, operator. I would like to remind everyone that comments made by management today and answers to questions will include forward-looking statements. Those include statements related to T2 Biosystems’ future financial and operating results and plans for developing and marketing new products. Forward-looking statements are based on estimates and assumpti

November 15, 2024 EX-99.1

T2 Biosystems Announces Third Quarter 2024 Financial Results Achieved 34% quarterly revenue growth compared to the prior year period

EX-99.1 Exhibit 99.1 T2 Biosystems Announces Third Quarter 2024 Financial Results Achieved 34% quarterly revenue growth compared to the prior year period LEXINGTON, Mass., November 14, 2024 (GLOBE NEWSWIRE)— T2 Biosystems, Inc. (NASDAQ:TTOO) (the “Company”), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today announced financial and operational result

November 15, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 14, 2024 T2 BIOSYSTEMS,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 14, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission F

November 14, 2024 EX-10.3

Amendment to Retention Bonus Letter Agreement, dated November 13, 2024, by and between T2 Biosystems, Inc. and Michael Gibbs

Exhibit 10.3 AMENDMENT TO RETENTION BONUS LETTER AGREEMENT This Amendment to Retention Bonus Letter Agreement is entered into as of November 13, 2024, by and between T2 Biosystems, Inc., a Delaware corporation having its principal place of business at 101 Hartwell Avenue, Lexington, Massachusetts 02421 USA (“T2 Bio”) and Michael Gibbs (“Employee”). Capitalized terms used herein without definition

November 14, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-36571 T2 Bi

November 14, 2024 SC 13G

TTOO / T2 Biosystems, Inc. / ARMISTICE CAPITAL, LLC Passive Investment

SC 13G 1 armistice-ttoo093024.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* T2 Biosystems, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 89853L302 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of this Statement) Check the appr

November 14, 2024 EX-10.1

Amendment No. 7 to Commercial Lease, dated October 30 2024, between Columbus Day Realty, Inc. and T2 Biosystems, Inc.

Exhibit 10.1 AMENDMENT NO. 7 TO COMMERCIAL LEASE BETWEEN COLUMBUS DAY REALTY, INC. AND T2 BIOSYSTEMS, INC. This Amendment No. 7 is to a Commercial Lease dated May 6, 2013, by and between Columbus Day Realty, Inc. (LESSOR), and T2 Biosystems, Inc. (LESSEE), which lease relates to the premises at 231 Andover Street, Wilmington, Massachusetts. WHEREAS, the Commercial Lease is dated May 6, 2013; WHERE

November 14, 2024 EX-10.2

Amendment to Retention Bonus Letter Agreement, dated November 13, 2024, by and between T2 Biosystems, Inc. and John Sprague

Exhibit 10.2 AMENDMENT TO RETENTION BONUS LETTER AGREEMENT This Amendment to Retention Bonus Letter Agreement is entered into as of November 13, 2024, by and between T2 Biosystems, Inc., a Delaware corporation having its principal place of business at 101 Hartwell Avenue, Lexington, Massachusetts 02421 USA (“T2 Bio”) and John Sprague (“Employee”). Capitalized terms used herein without definition s

November 8, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 7, 2024 T2 BIOSYSTEMS, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 7, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fi

November 8, 2024 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Ame

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy S

November 6, 2024 EX-99.1

Joint Filing Agreement

EX-99.1 2 ex991tosc13g10871ttoo110624.htm Exhibit 99.1 Joint Filing Agreement The undersigned hereby agree that the Statement on Schedule 13G dated November 6, 2024 with respect to the Common Stock, par value $0.001 per share, of T2 Biosystems, Inc., a Delaware corporation, and any further amendments thereto executed by each and any of the undersigned shall be filed on behalf of each of the unders

November 6, 2024 SC 13G

TTOO / T2 Biosystems, Inc. / Safier Jacob Passive Investment

SC 13G 1 sc13g10871ttoo11062024.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No. )1 T2 Biosystems, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securi

November 6, 2024 SC 13G

TTOO / T2 Biosystems, Inc. / JSAF Holdings, LLC Passive Investment

SC 13G 1 sc13g10871ttoo11062024.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No. )1 T2 Biosystems, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securi

November 6, 2024 EX-99.1

Joint Filing Agreement

EX-99.1 2 ex991tosc13g10871ttoo110624.htm Exhibit 99.1 Joint Filing Agreement The undersigned hereby agree that the Statement on Schedule 13G dated November 6, 2024 with respect to the Common Stock, par value $0.001 per share, of T2 Biosystems, Inc., a Delaware corporation, and any further amendments thereto executed by each and any of the undersigned shall be filed on behalf of each of the unders

October 16, 2024 EX-99.1

1

Exhibit 99.1 T2 Biosystems Business Update October 10, 2024 Trip Taylor, IR Thank you, operator. I would like to remind everyone that comments made by management today and answers to questions will include forward-looking statements. Those include statements related to T2 Biosystems’ future financial and operating results and plans for developing and marketing new products. Forward-looking stateme

October 16, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 10, 2024 T2 BIOSYSTEMS, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 10, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fi

October 7, 2024 EX-99.1

T2 Biosystems Announces Preliminary Third Quarter 2024 Financial Results Achieved 35% increase in total revenue compared to prior year period

Exhibit 99.1 T2 Biosystems Announces Preliminary Third Quarter 2024 Financial Results Achieved 35% increase in total revenue compared to prior year period LEXINGTON, Mass., October 7, 2024 (GLOBE NEWSWIRE)—T2 Biosystems, Inc. (NASDAQ: TTOO), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today announced preliminary unaudited financial and operational r

October 7, 2024 8-K

Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 7, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fil

September 20, 2024 EX-99.1

T2 Biosystems Achieves Successful Defense of Patent for Direct-From-Whole Blood Pathogen Detection Method in the European Union

EX-99.1 Exhibit 99.1 T2 Biosystems Achieves Successful Defense of Patent for Direct-From-Whole Blood Pathogen Detection Method in the European Union LEXINGTON, Mass., September 20, 2024 (GLOBE NEWSWIRE)— T2 Biosystems, Inc. (NASDAQ:TTOO) (the “Company”), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today announced that it has successfully defended ag

September 20, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 20, 2024 T2 BIOSYSTEMS,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 20, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission

September 16, 2024 8-K

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 16, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission

September 16, 2024 EX-99.1

T2 Biosystems Receives FDA Clearance to Market the T2Candida Panel for Pediatric Patients Expands available market to include over 200 children’s hospitals in the United States

Exhibit 99.1 T2 Biosystems Receives FDA Clearance to Market the T2Candida Panel for Pediatric Patients Expands available market to include over 200 children’s hospitals in the United States LEXINGTON, Mass., September 16, 2024 (GLOBE NEWSWIRE)— T2 Biosystems, Inc. (NASDAQ:TTOO) (the “Company”), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today annou

September 9, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 9, 2024 T2 BIOSYSTEMS,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 9, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission F

September 9, 2024 EX-99.1

T2 Biosystems Provides Updates on its New Product Development Pipeline Progress Company plans to launch multiple direct-from-blood diagnostics over the next 15 months for antimicrobial resistance, pediatric Candida infections, Lyme disease, and Candi

EX-99.1 Exhibit 99.1 T2 Biosystems Provides Updates on its New Product Development Pipeline Progress Company plans to launch multiple direct-from-blood diagnostics over the next 15 months for antimicrobial resistance, pediatric Candida infections, Lyme disease, and Candida auris LEXINGTON, Mass., September 9, 2024 (GLOBE NEWSWIRE)— T2 Biosystems, Inc. (NASDAQ:TTOO) (the “Company”), a leader in the

August 23, 2024 424B5

Up to $13,390,000 Common Stock

As Filed Pursuant to Rule 424(b)(5) Registration No. 333-280922 PROSPECTUS SUPPLEMENT (To Sales Agreement Prospectus dated July 29, 2024) Up to $13,390,000 Common Stock This Prospectus Supplement supplements the sales agreement prospectus, dated July 29, 2024 (the “ATM Prospectus”), relating to the offer and sale of shares of our common stock, $0.001 par value per share (“common stock”), having an

August 15, 2024 SC 13G/A

TTOO / T2 Biosystems, Inc. / New Dimensions Trading Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No. 1)1 T2 Biosystems, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 89853L302 (CUSIP Number) Apri

August 15, 2024 SC 13G/A

TTOO / T2 Biosystems, Inc. / Safier Jacob Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No. 1)1 T2 Biosystems, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 89853L302 (CUSIP Number) Apri

August 8, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-36571 T2 Biosyst

July 29, 2024 EX-99.1

T2 Biosystems Announces Second Quarter 2024 Financial Results Achieved record quarterly and first half sepsis test revenue, representing growth of 27% and 25% respectively compared to the prior year periods

Exhibit 99.1 T2 Biosystems Announces Second Quarter 2024 Financial Results Achieved record quarterly and first half sepsis test revenue, representing growth of 27% and 25% respectively compared to the prior year periods LEXINGTON, Mass., July 29, 2024 (GLOBE NEWSWIRE)— T2 Biosystems, Inc. (NASDAQ:TTOO) (the “Company”), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resi

July 29, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 29, 2024 T2 BIOSYSTEMS, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 29, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File

July 29, 2024 EX-99.2

1

Exhibit 99.2 T2 Biosystems 2Q 2024 July 29, 2024 KLG Comments: 7.29.24 Trip Taylor, IR Thank you, operator. I would like to remind everyone that comments made by management today and answers to questions will include forward-looking statements. Those include statements related to T2 Biosystems’ future financial and operating results and plans for developing and marketing new products. Forward-look

July 26, 2024 CORRESP

T2 Biosystems, Inc. 101 Hartwell Avenue Lexington, Massachusetts 02421

T2 Biosystems, Inc. 101 Hartwell Avenue Lexington, Massachusetts 02421 July 26, 2024 Via EDGAR Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Re: T2 Biosystems, Inc. Registration Statement on Form S-3 Filed July 19, 2024 File No. 333-280922 To whom it may concern: Pursuant to Rule 461(a) under the Securities Act

July 19, 2024 EX-1.2

At The Market Offering Agreement, dated as of July 19, 2024, by and between T2 Biosystems, Inc. and H.C. Wainwright & Co., LLC.

Exhibit 1.2 AT THE MARKET OFFERING AGREEMENT July 19, 2024 H.C. Wainwright & Co., LLC 430 Park Avenue New York, New York 10022 Ladies and Gentlemen: T2 Biosystems, Inc., a corporation organized under the laws of Delaware (the “Company”), confirms its agreement (this “Agreement”) with H.C. Wainwright & Co., LLC (the “Manager”) as follows: 1. Definitions. The terms that follow, when used in this Agr

July 19, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 19, 2024 T2 BIOSYSTEMS, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 19, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File

July 19, 2024 EX-4.2

Form of Indenture.

Exhibit 4.2 T2 BIOSYSTEMS, INC. INDENTURE Dated as of , 20 [] Trustee TABLE OF CONTENTS Page Article I. DEFINITIONS AND INCORPORATION BY REFERENCE 1 Section 1.1 Definitions 1 Section 1.2 Other Definitions 4 Section 1.3 Incorporation by Reference of Trust Indenture Act 5 Section 1.4 Rules of Construction 5 Article II. THE SECURITIES 5 Section 2.1 Issuable in Series 5 Section 2.2 Establishment of Te

July 19, 2024 S-3

As filed with the Securities and Exchange Commission on July 19, 2024.

Table of Contents As filed with the Securities and Exchange Commission on July 19, 2024.

July 19, 2024 EX-FILING FEES

Filing Fee Table

Exhibit 107 CALCULATION OF FILING FEE TABLE Registration Statement on Form S-3 (Form Type) T2 Biosystems, Inc.

May 31, 2024 CORRESP

T2 Biosystems, Inc. 101 Hartwell Avenue Lexington, Massachusetts 02421

T2 Biosystems, Inc. 101 Hartwell Avenue Lexington, Massachusetts 02421 May 31, 2024 Via EDGAR Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Re: T2 Biosystems, Inc. Registration Statement on Form S-3 Filed May 28, 2024 File No. 333-279740 To whom it may concern: Pursuant to Rule 461(a) under the Securities Act of

May 28, 2024 EX-FILING FEES

Filing Fee Table.

EX-FILING FEES Exhibit 107 Calculation of Filing Fee Table Registration Statement on Form S-1 (Form Type) T2 Biosystems, Inc.

May 28, 2024 S-3

As filed with the Securities and Exchange Commission on May 24, 2024

S-3 Table of Contents As filed with the Securities and Exchange Commission on May 24, 2024 Registration No.

May 22, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 21, 2024 T2 BIOSYSTEMS, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 21, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File N

May 20, 2024 EX-10.1

Form of Securities Purchase Agreement, dated as of May 14, 2024, by and between the Company and the Purchaser party thereto.

EX-10.1 Exhibit 10.1 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of May 14, 2024, between T2 Biosystems, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”). WHEREAS, subject to the terms and conditio

May 20, 2024 EX-4.1

Form of Pre-Funded Warrant.

EX-4.1 Exhibit 4.1 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE

May 20, 2024 EX-4.2

Form of Series A Warrant.

EX-4.2 Exhibit 4.2 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE

May 20, 2024 EX-4.3

Form of Series B Warrant.

EX-4.3 Exhibit 4.3 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE

May 20, 2024 EX-10.2

Form of Registration Rights Agreement, dated as of May 14, 2024, by and between the Company and the Investor party thereto.

Exhibit 10.2 EXHIBIT B REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (this “Agreement”) is made and entered into as of May 14, 2024, by and between T2 Biosystems, Inc., a Delaware corporation (the “Company”), and each of the several purchasers signatory hereto (each such purchaser, a “Purchaser” and, collectively, the “Purchasers”). This Agreement is made pursuant to the Securit

May 20, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 14, 2024 T2 BIOSYSTEMS, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 14, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File N

May 20, 2024 EX-4.4

Form of Wainwright Warrant.

EX-4.4 Exhibit 4.4 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE

May 14, 2024 RW

T2 Biosystems, Inc. 101 Hartwell Avenue Lexington, MA 02421

T2 Biosystems, Inc. 101 Hartwell Avenue Lexington, MA 02421 May 14, 2024 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: T2 Biosystems, Inc. Registration Statement on Form S-1 File No. 333-278866 Ladies and Gentlemen: T2 Biosystems, Inc. (the “Company”) hereby respectfully requests pursuant to Rule 477 of the Securitie

May 14, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 9, 2024 T2 BIOSYSTEMS, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 9, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File Nu

May 13, 2024 SC 13D/A

TTOO / T2 Biosystems, Inc. / CR Group L.P. - SC 13D/A Activist Investment

SC 13D/A 1 d838783dsc13da.htm SC 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 2)* T2 Biosystems, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 89853L302 (CUSIP Number) Andrei Dorenbaum c/o CR Group L.P. 1000 Main Street, Suite 2500 Houston, TX 77002

May 8, 2024 FWP

T2 Biosystems Announces Letter of Intent to Enter Strategic Partnership for Lyme Disease Advances plan to launch T2Lyme Panel for detection of early Lyme disease

FWP Filed Pursuant to Rule 433 Issuer Free Writing Prospectus dated May 6, 2024 Relating to Preliminary Prospectus dated May 6, 2024 Registration No.

May 7, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 7, 2024 T2 BIOSYSTEMS, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 7, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File Nu

May 7, 2024 SC 13D/A

TTOO / T2 Biosystems, Inc. / CR Group L.P. - SC 13D/A Activist Investment

SC 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 1)* T2 Biosystems, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 89853L302 (CUSIP Number) Andrei Dorenbaum c/o CR Group L.P. 1000 Main Street, Suite 2500 Houston, TX 77002 (703) 209-7350 (Name, Address

May 7, 2024 FWP

Strengthens balance sheet by reducing total debt by approximately 80% over the past year

T2 Biosystems Announces the Conversion of an Additional $15 Million of CRG Term Loan into Equity Strengthens balance sheet by reducing total debt by approximately 80% over the past year Filed Pursuant to Rule 433 Issuer Free Writing Prospectus dated May 6, 2024 Relating to Preliminary Prospectus dated May 6, 2024 Registration No.

May 7, 2024 FWP

T2 Biosystems Announces Commercial Expansion Through Middle East Distributor

T2 Biosystems Announces Commercial Expansion Through Middle East Distributor Filed Pursuant to Rule 433 Issuer Free Writing Prospectus dated May 6, 2024 Relating to Preliminary Prospectus dated May 6, 2024 Registration No.

May 6, 2024 S-1/A

As filed with the Securities and Exchange Commission on May 6, 2024

Table of Contents As filed with the Securities and Exchange Commission on May 6, 2024 Registration No.

May 6, 2024 S-1/A

Power of Attorney (included on the signature page)

S-1/A Table of Contents As filed with the Securities and Exchange Commission on May 6, 2024 Registration No.

May 6, 2024 EX-10.65

Form of Series B-2 Warrant

EX-10.65 Exhibit 10.65 SERIES B-2 WARRANT TO PURCHASE SHARES OF COMMON STOCK T2 BIOSYSTEMS, INC. Warrant Shares: Original Issuance Date: [ ], 2024 Initial Exercise Date: [ ], 2024 THIS SERIES B-2 WARRANT TO PURCHASE SHARES OF COMMON STOCK (this “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the

May 6, 2024 EX-10.1

Securities Purchase Agreement, dated May 3, 2024 by and between the Company and the Lenders party thereto

EX-10.1 Exhibit 10.1 Execution Version SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is made as of May 3, 2024, by and among CRG Partners III L.P., CRG Partners III—Parallel Fund “A” L.P., CRG Partners III (Cayman) Unlev AIV I L.P., CRG Partners III (Cayman) Lev AIV I L.P. and CRG Partners III Parallel Fund “B” (Cayman) L.P. (together, “CRG” or the “Purchasers

May 6, 2024 EX-99.1

T2 Biosystems Announces First Quarter 2024 Financial Results Achieved double-digit growth in sepsis product revenue and reduced debt by approximately 80% compared to the prior year period

Exhibit 99.1 T2 Biosystems Announces First Quarter 2024 Financial Results Achieved double-digit growth in sepsis product revenue and reduced debt by approximately 80% compared to the prior year period LEXINGTON, Mass., May 6, 2024 (GLOBE NEWSWIRE)— T2 Biosystems, Inc. (NASDAQ:TTOO) (the “Company”), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today a

May 6, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 3, 2024 T2 BIOSYSTEMS, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 3, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File Nu

May 6, 2024 EX-10.2

Consent and Amendment No. 11 to Term Loan Agreement, dated May 3, 2024 by and between the Company and the Lenders party thereto

EX-10.2 Exhibit 10.2 CONSENT AND AMENDMENT NO. 11 TO TERM LOAN AGREEMENT THIS CONSENT AND AMENDMENT NO. 11 TO TERM LOAN AGREEMENT, dated as of May 3, 2024 (this “Amendment”), is made among T2 BIOSYSTEMS, INC., a Delaware corporation (“Borrower”), the other Obligors party hereto, CRG SERVICING LLC, as administrative agent and collateral agent (in such capacities, “Administrative Agent”) and the len

May 6, 2024 EX-10.64

Form of Series B-1 Warrant

EX-10.64 Exhibit 10.64 SERIES B-1 WARRANT TO PURCHASE SHARES OF COMMON STOCK T2 BIOSYSTEMS, INC. Warrant Shares: Original Issuance Date: [ ], 2024 Initial Exercise Date: [ ], 2024 THIS SERIES B-1 WARRANT TO PURCHASE SHARES OF COMMON STOCK (this “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the

May 6, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-36571 T2 Biosys

May 6, 2024 EX-10.63

Form of Securities Purchase Agreement

EX-10.63 Exhibit 10.63 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of May [ ], 2024, between T2 Biosystems, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”). WHEREAS, subject to the terms and condi

May 6, 2024 EX-1.1

Form of Placement Agency Agreement

EX-1.1 Exhibit 1.1 A.G.P./Alliance Global Partners 590 Madison Avenue, 28th Floor New York, NY 10022 May [ ], 2024 T2 Biosystems, Inc. Attention: John Sperzel 101 Hartwell Avenue Lexington, MA 02421 Re: Placement Agency Agreement Dear Mr. Sperzel: Subject to the terms and conditions of this letter agreement (the “Agreement”) between A.G.P./Alliance Global Partners (the “Placement Agent”), as sole

May 6, 2024 EX-FILING FEES

Filing Fee Table

EX-FILING FEES Exhibit 107 Calculation of Filing Fee Table Registration Statement on Form S-1 (Form Type) T2 Biosystems, Inc.

May 6, 2024 EX-10.66

Form of Prefunded Warrant

EX-10.66 Exhibit 10.66 PRE-FUNDED WARRANT TO PURCHASE SHARES OF COMMON STOCK T2 BIOSYSTEMS, INC. Warrant Shares: Issue Date: [ ], 2024 THIS PRE-FUNDED WARRANT TO PURCHASE SHARES OF COMMON STOCK (this “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any tim

May 6, 2024 EX-99.2

1

EX-99.2 Exhibit 99.2 T2 Biosystems 1Q 2024 May 6, 2024 Trip Taylor, IR Thank you, operator. I would like to remind everyone that comments made by management today and answers to questions will include forward-looking statements. Those include statements related to T2 Biosystems’ future financial and operating results and plans for developing and marketing new products. Forward-looking statements a

April 22, 2024 S-1

As filed with the Securities and Exchange Commission on April 22, 2024

Table of Contents As filed with the Securities and Exchange Commission on April 22, 2024 Registration No.

April 22, 2024 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Table Registration Statement on Form S-1 (Form Type) T2 Biosystems, Inc.

April 19, 2024 SC 13D

TTOO / T2 Biosystems, Inc. / CR Group L.P. - SC 13D Activist Investment

SC 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. )* T2 Biosystems, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 89853L302 (CUSIP Number) Andrei Dorenbaum c/o CR Group L.P. 1000 Main Street, Suite 2500 Houston, TX 77002 (703) 209-7350 (Name, Address an

April 19, 2024 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 2 d830497dex991.htm EX-99.1 CUSIP No. 89853L302 Page 13 of 13 EXHIBIT 99.1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the undersigned agree to the joint filing on behalf of each of them of a statement on Schedule 13D (including amendments thereto) with respect to the Common Stock of T2 Biosystems, Inc. and further agree th

April 18, 2024 EX-3.1

Certificate of Designation of Preferences, Rights and Limitations of Series A Convertible Preferred Stock (incorporated by reference to Exhibit 3.1 of the Company’s Form 8-K (File No. 001-36571) filed on April 18, 2024)

Exhibit 3.1 T2 BIOSYSTEMS, INC. CERTIFICATE OF DESIGNATION OF PREFERENCES, RIGHTS AND LIMITATIONS OF SERIES A CONVERTIBLE PREFERRED STOCK PURSUANT TO SECTION 151 OF THE DELAWARE GENERAL CORPORATION LAW T2 BIOSYSTEMS, INC., Delaware corporation (the “Corporation”), in accordance with the provisions of Section 103 of the Delaware General Corporation Law (the “DGCL”) does hereby certify that, in acco

April 18, 2024 EX-10.1

Consent and Amendment No. 10 to Term Loan Agreement, dated April 12, 2024, by and among the Company, CRG Servicing LLC as administrative agent and collateral agent, and the lenders party thereto (incorporated by reference to Exhibit 10.1 of the Company’s Form 8-K (File No. 001-36571) filed on April 18, 2024)

Exhibit 10.1 Execution Version CONSENT AND AMENDMENT NO. 10 TO TERM LOAN AGREEMENT THIS CONSENT AND AMENDMENT NO. 10 TO TERM LOAN AGREEMENT, dated as of April 12, 2024 (this “Consent”) is made among T2 BIOSYSTEMS, INC., a Delaware corporation (“Borrower”), the other Obligors party hereto, CRG SERVICING LLC, as administrative agent and collateral agent (in such capacities, “Administrative Agent”) a

April 18, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 12, 2024 T2 BIOSYSTEMS, INC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 12, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File

April 12, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 11, 2024 T2 BIOSYSTEMS, INC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 11, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File

April 1, 2024 EX-21.1

List of Subsidiaries (incorporated by reference to Exhibit 21.1 of the Company’s Form 10-K (File No. 001-36571) filed on April 1, 2024)

Exhibit 21.1 Subsidiaries of T2 Biosystems, Inc.: Name Jurisdiction of Organization T2 Biosystems Securities Corporation Massachusetts

April 1, 2024 EX-4.4

Description of Securities (incorporated by reference to Exhibit 4.4 of the Company’s Form 10-K (File No. 001-36571) filed on April 1, 2024)

Exhibit 4.4 DESCRIPTION OF THE REGISTRANT’S SECURITIES REGISTERED UNDER SECTION 12 OF THE EXCHANGE ACT General As of December 31, 2023, T2 Biosystems, Inc. had one class of securities registered under Section 12 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). References herein to “we,” “us,” “our” and the “Company” refer to T2 Biosystems, Inc. and not to any of its subsidi

April 1, 2024 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-36571 T2 Biosystems, In

April 1, 2024 EX-10.61

Letter Agreement, dated March 31, 2024, by and between T2 Biosystems, Inc. and Michael Gibbs (incorporated by reference to Exhibit 10.61 of the Company’s Form 10-K (File No. 001-36571) filed on April 1, 2024)

Exhibit 10.61 March 31, 2024 Michael Gibbs Re: Retention Bonus Dear Michael, T2 Biosystems, Inc. (the “Company” or “T2”) is pleased to inform you that you are eligible to earn a special, one-time retention bonus (the “Retention Bonus”) in the total aggregate amount of $80,000, to be paid in two installments of $40,000, pursuant to the terms and conditions set forth in this letter agreement. Subjec

April 1, 2024 EX-97.1

T2 Biosystems, Inc. Clawback Policy

Exhibit 97.1 T2 BIOSYSTEMS, INC. POLICY FOR RECOVERY OF ERRONEOUSLY AWARDED COMPENSATION T2 Biosystems, Inc. (the “Company”) has adopted this Policy for Recovery of Erroneously Awarded Compensation (the “Policy”), effective as of October 2, 2023 (the “Effective Date”). Capitalized terms used in this Policy but not otherwise defined herein are defined in Section 11. 1. Persons Subject to Policy Thi

April 1, 2024 EX-10.60

Letter Agreement, dated March 31, 2024, by and between T2 Biosystems, Inc. and John Sprague (incorporated by reference to Exhibit 10.60 of the Company’s Form 10-K (File No. 001-36571) filed on April 1, 2024)

Exhibit 10.60 March 31, 2024 John Sprague Re: Retention Bonus Dear Michael, T2 Biosystems, Inc. (the “Company” or “T2”) is pleased to inform you that you are eligible to earn a special, one-time retention bonus (the “Retention Bonus”) in the total aggregate amount of $80,000, to be paid in two installments of $40,000, pursuant to the terms and conditions set forth in this letter agreement. Subject

March 28, 2024 EX-99.1

T2 Biosystems Announces Extension of Multi-Year Capital Equipment Supplier Agreement with Vizient, Inc.

EX-99.1 Exhibit 99.1 T2 Biosystems Announces Extension of Multi-Year Capital Equipment Supplier Agreement with Vizient, Inc. LEXINGTON, Mass., March 28, 2024 (GLOBE NEWSWIRE) — T2 Biosystems, Inc. (NASDAQ:TTOO), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today announced that its multi-year capital equipment supplier agreement with Vizient, Inc., th

March 28, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 28, 2024 T2 BIOSYSTEMS, INC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 28, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File

March 20, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2024 T2 BIOSYSTEMS, INC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File

March 20, 2024 EX-99.1

T2 Biosystems Unveils T2Lyme Launch Plans and Provides Additional Business Updates Anticipates commercial launch of the T2Lyme Panel in the third quarter of 2024

EX-99.1 Exhibit 99.1 T2 Biosystems Unveils T2Lyme Launch Plans and Provides Additional Business Updates Anticipates commercial launch of the T2Lyme Panel in the third quarter of 2024 LEXINGTON, Mass., March 20, 2024 (GLOBE NEWSWIRE)— T2 Biosystems, Inc. (NASDAQ:TTOO) (the “Company”), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today announced plans

March 20, 2024 EX-99.2

1

EX-99.2 Exhibit 99.2 T2 Biosystems Investor Update March 20, 2024 Trip Taylor, IR Thank you, operator. I would like to remind everyone that comments made by management today and answers to questions will include forward-looking statements. Those include statements related to T2 Biosystems’ future financial and operating results and plans for developing and marketing new products. Forward-looking s

March 18, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 18, 2024 T2 BIOSYSTEMS, INC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 18, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File

March 18, 2024 EX-99.1

T2 Biosystems Announces New Publication Highlighting the Clinical Benefits and Performance of the T2Resistance Panel Study demonstrates T2Resistance Panel utilization enables faster targeted therapy based on direct-from-blood detection of resistance

Exhibit 99.1 T2 Biosystems Announces New Publication Highlighting the Clinical Benefits and Performance of the T2Resistance Panel Study demonstrates T2Resistance Panel utilization enables faster targeted therapy based on direct-from-blood detection of resistance genes LEXINGTON, Mass., March 18, 2024 (GLOBE NEWSWIRE)— T2 Biosystems, Inc. (NASDAQ:TTOO) (the “Company”), a leader in the rapid detecti

March 12, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 11, 2024 T2 BIOSYSTEMS, INC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 11, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File

March 11, 2024 SC 13G

TTOO / T2 Biosystems, Inc. / New Dimensions Trading Passive Investment

SC 13G 1 sc13g1087100103112024.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No. )1 T2 Biosystems, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securit

March 11, 2024 EX-99.1

Joint Filing Agreement

EX-99.1 2 ex991to13g10871001031124.htm JOINT FILING AGREEMENT Exhibit 99.1 Joint Filing Agreement The undersigned hereby agree that the Statement on Schedule 13G dated March 11, 2024 with respect to the Common Stock, par value $0.001 per share, of T2 Biosystems, Inc., a Delaware corporation, and any amendments thereto executed by each and any of the undersigned shall be filed on behalf of each of

March 11, 2024 EX-99.1

Joint Filing Agreement

EX-99.1 2 ex991to13g10871001b031124.htm JOINT FILING AGREEMENT Exhibit 99.1 Joint Filing Agreement The undersigned hereby agree that the Statement on Schedule 13G dated March 11, 2024 with respect to the Common Stock, par value $0.001 per share, of T2 Biosystems, Inc., a Delaware corporation, and any amendments thereto executed by each and any of the undersigned shall be filed on behalf of each of

March 11, 2024 SC 13G

TTOO / T2 Biosystems, Inc. / Safier Jacob Passive Investment

SC 13G 1 sc13g10871001b03112024.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No. )1 T2 Biosystems, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securi

March 4, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Ame

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy S

February 16, 2024 EX-99.1

1

EX-99.1 Exhibit 99.1 T2 Biosystems 4Q 2023 February 15, 2024 Trip Taylor, IR Thank you, operator. I would like to remind everyone that comments made by management today and answers to questions will include forward-looking statements. Those include statements related to T2 Biosystems’ future financial and operating results and plans for developing and marketing new products. Forward-looking statem

February 16, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 15, 2024 T2 BIOSYSTEMS,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 15, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission F

February 15, 2024 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Ame

PRE 14A Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

February 15, 2024 EX-10.1

Securities Purchase Agreement, dated February 15, 2024 by and between the Company and the Lenders party thereto (incorporated by reference to Exhibit 10.1 of the Company’s Form 8-K (File No. 001-36571) filed on February 15, 2024)

EX-10.1 Exhibit 10.1 Execution Version SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is made as of February 15, 2024, by and among CRG Partners III L.P., CRG Partners III - Parallel Fund “A” L.P., CRG Partners III (Cayman) Unlev AIV I L.P., CRG Partners III (Cayman) Lev AIV I L.P. and CRG Partners III Parallel Fund “B” (Cayman) L.P. (together, “CRG” or the “Pu

February 15, 2024 EX-99.1

T2 Biosystems Announces Preliminary Fourth Quarter and Full Year 2023 Financial Results Advanced multiple new products and achieved record fourth quarter U.S. T2Bacteria Panel sales

EX-99.1 Exhibit 99.1 T2 Biosystems Announces Preliminary Fourth Quarter and Full Year 2023 Financial Results Advanced multiple new products and achieved record fourth quarter U.S. T2Bacteria Panel sales LEXINGTON, Mass., February 15, 2024 (GLOBE NEWSWIRE)— T2 Biosystems, Inc. (NASDAQ:TTOO) (the “Company”), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes,

February 15, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 15, 2024 T2 BIOSYSTEMS,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 15, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission F

February 13, 2024 EX-99.1

JOINT FILING AGREEMENT

Exhibit 99.1 JOINT FILING AGREEMENT The undersigned hereby agree that a single Schedule 13G (or any amendment thereto) relating to the Common Stock, par value $0.001 per share, of T2 Biosystems, Inc. shall be filed on behalf of each of the undersigned and that this Agreement shall be filed as an exhibit to such Schedule 13G. February 13, 2024 LIND GLOBAL FUND II LP By: Lind Global Partners II LLC

February 13, 2024 SC 13G/A

US89853L3024 / T2 BIOSYSTEMS INC COM USD0 001 / Lind Global Fund II LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* T2 Biosystems, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 89853L302 (CUSIP Number) December 31, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rul

January 5, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 2, 2024 T2 BIOSYSTEMS, IN

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 2, 2024 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fil

November 24, 2023 8-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A (Amendment No. 1) CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 31, 2

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A (Amendment No. 1) CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 31, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorpora

November 15, 2023 NT 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 12b-25 NOTIFICATION OF LATE FILING

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 12b-25 NOTIFICATION OF LATE FILING (Check One): ☐ 10-K ☐ Form 20-F ☐ Form 11-K ☒ Form 10-Q ☐ Form 10-D ☐ Form N-CEN ☐ Form N-CSR For Period Ended: September 30, 2023 ☐ Transition Report on Form 10-K ☐ Transition Report on Form 20-F ☐ Transition Report on Form 11-K ☐ Transition Report on Form 10-Q For the Transition Period Ended: Read Instruction (on back page) Before Preparing Form.

November 15, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-36571 T2 Bi

November 15, 2023 EX-10.5

Amendment No. 9 to Term Loan Agreement, dated October 18, 2023, between T2 Biosystems, Inc. and CRG Servicing LLC (incorporated by reference to Exhibit 10.5 of the Company’s Form 10-Q (File No. 001-36571) filed on November 15, 2023)

Exhibit 10.5 Execution Version AMENDMENT No. 9 TO TERM LOAN AGREEMENT THIS AMENDMENT NO. 9 TO TERM LOAN AGREEMENT, dated as of October 18, 2023 (this “Amendment”) is made among T2 BIOSYSTEMS, INC., a Delaware corporation (“Borrower”), the other Obligors party hereto, CRG SERVICING LLC, as administrative agent and collateral agent (in such capacities, “Administrative Agent”) and the lenders listed

November 15, 2023 EX-10.4

2014 Employee Stock Purchase Plan, as amended and restated (incorporated by reference to Exhibit 10.4 of the Company’s Form 10-Q (File No. 001-36571) filed on November 15, 2023)

Exhibit 10.4 T2 BIOSYSTEMS, INC. 2014 EMPLOYEE STOCK PURCHASE PLAN (as amended and restated effective October 12, 2023) ARTICLE 1. PURPOSE The purposes of this T2 Biosystems, Inc. 2014 Employee Stock Purchase Plan (as it may be amended or restated from time to time, the “Plan”) are to assist Eligible Employees of T2 Biosystems, Inc., a Delaware corporation (the “Company”), and its Designated Subsi

November 15, 2023 EX-10.3

T2 Biosystems, Inc. 2014 Incentive Award Plan, as amended and restated (incorporated by reference to Exhibit 10.3 of the Company’s Form 10-Q (File No. 001-36571) filed on November 15, 2023)

Exhibit 10.3 T2 BIOSYSTEMS, INC. 2014 INCENTIVE AWARD PLAN (as amended and restated effective October 12, 2023) ARTICLE 1. PURPOSE The purpose of the T2 Biosystems, Inc. 2014 Incentive Award Plan (as it may be amended or restated from time to time, the “Plan”) is to promote the success and enhance the value of T2 Biosystems, Inc. (the “Company”) by linking the individual interests of the members o

November 1, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 31, 2023 T2 BIOSYSTEMS, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 31, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fi

October 25, 2023 EX-99.1

T2 Biosystems Highlights New Clinical Data Presented at IDWeek 2023 Conference

EX-99.1 Exhibit 99.1 T2 Biosystems Highlights New Clinical Data Presented at IDWeek 2023 Conference Data demonstrates speed, accuracy, and clinical benefits of the T2Dx Instrument and T2 Biosystems’ sepsis panels, including encouraging early detection data for T2Resistance Panel LEXINGTON, Mass., October 24, 2023 (GLOBE NEWSWIRE)—T2 Biosystems, Inc. (NASDAQ:TTOO), a leader in the rapid detection o

October 25, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 24, 2023 T2 BIOSYSTEMS, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 24, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fi

October 23, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 18, 2023 T2 BIOSYSTEMS, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 18, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fi

October 17, 2023 EX-99.1

1

EX-99.1 Exhibit 99.1 T2 Biosystems 3Q 2023 October 12, 2023 Trip Taylor, IR Thank you, operator. I would like to remind everyone that comments made by management today and answers to questions will include forward-looking statements. Those include statements related to T2 Biosystems’ future financial and operating results and plans for developing and marketing new products. Forward-looking stateme

October 17, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 12, 2023 T2 BIOSYSTEMS, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 12, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fi

October 12, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 12, 2023 T2 BIOSYSTEMS, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 12, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fi

October 12, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 12, 2023 T2 BIOSYSTEMS, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 12, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fi

October 12, 2023 EX-3.1

Certificate of Amendment of Restated Certificate of Incorporation of the Company dated October 12, 2023 (incorporated by reference to Exhibit 3.1 of the Company’s Form 8-K (File No. 001-36571) filed on October 12, 2023)

EX-3.1 Exhibit 3.1 CERTIFICATE OF AMENDMENT OF RESTATED CERTIFICATE OF INCORPORATION OF T2 BIOSYSTEMS, INC. T2 Biosystems, Inc., a corporation organized and existing under and by virtue of the General Corporation Law of the State of Delaware (the “Company”), does hereby certify as follows: FIRST: That, the Board of Directors of the Company duly adopted resolutions by unanimous written consent in a

October 12, 2023 EX-99.1

T2 Biosystems Announces Preliminary Third Quarter 2023 Financial Results and Business Updates

EX-99.1 Exhibit 99.1 T2 Biosystems Announces Preliminary Third Quarter 2023 Financial Results and Business Updates Received FDA 510(k) clearance for the T2Biothreat Panel and significantly strengthened balance sheet LEXINGTON, Mass., October 12, 2023 (GLOBE NEWSWIRE)—T2 Biosystems, Inc. (NASDAQ:TTOO) (the “Company”), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resist

October 12, 2023 EX-99.2

T2 Biosystems Announces FDA 510(k) Submission to Expand the Pathogen Detection on its

EX-99.2 Exhibit 99.2 T2 Biosystems Announces FDA 510(k) Submission to Expand the Pathogen Detection on its FDA-Cleared T2Bacteria Panel to Include Detection of Acinetobacter baumannii LEXINGTON, Mass., October 12, 2023 (GLOBE NEWSWIRE)—T2 Biosystems, Inc. (NASDAQ:TTOO), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today announced that it has submitte

September 18, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 15, 2023 T2 BIOSYSTEMS,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 15, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission

September 13, 2023 CORRESP

T2 Biosystems, Inc. 101 Hartwell Avenue Lexington, MA 02421

T2 Biosystems, Inc. 101 Hartwell Avenue Lexington, MA 02421 September 13, 2023 VIA EDGAR TRANSMISSION U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: T2 Biosystems, Inc. Registration Statement on Form S-3 File No. 333-274182 To the addressee set forth above: T2 Biosystems, Inc. (the “Company”) hereby respectfully requests the wi

September 12, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Ame

DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ ☐ Preliminary Proxy Statement ☐ Confidential, for Use of t

September 11, 2023 CORRESP

T2 Biosystems, Inc. 101 Hartwell Avenue Lexington, MA 02421

T2 Biosystems, Inc. 101 Hartwell Avenue Lexington, MA 02421 September 11, 2023 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: T2 Biosystems, Inc. Registration Statement on Form S-3 File No. 333-274182 To the addressee set forth above: Pursuant to Rule 461 of Regulation C of the General Rules and Regulations under the

August 24, 2023 S-3

As filed with the Securities and Exchange Commission on August 24, 2023

S-3 Table of Contents As filed with the Securities and Exchange Commission on August 24, 2023 Registration No.

August 24, 2023 EX-FILING FEES

Filing Fee Table.

EX-FILING FEES Exhibit 107 Calculation of Filing Fee Table Form S-3 (Form Type) T2 Biosystems, Inc.

August 18, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, fo

August 11, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2023 T2 BIOSYSTEMS, INC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File

August 11, 2023 EX-99.2

1

EX-99.2 Exhibit 99.2 T2 Biosystems 2Q August 7, 2023 Trip Taylor, IR Thank you, operator. I would like to remind everyone that comments made by management today and answers to questions will include forward-looking statements. Those include statements related to T2 Biosystems’ future financial and operating results and plans for developing and marketing new products. Forward-looking statements are

August 11, 2023 EX-99.1

T2 BIOSYSTEMS, INC. CONDENSED CONSOLIDATED BALANCE SHEETS (In thousands, except share and per share data) June 30, 2023 December 31, 2022 Assets Current assets: Cash and cash equivalents $ 16,084 $ 10,329 Accounts receivable 1,349 2,163 Inventories 4

EX-99.1 Exhibit 99.1 T2 Biosystems Announces Second Quarter 2023 Financial Results Received FDA Breakthrough Device Designation for Candida auris test, achieved record quarterly sepsis test panel orders and received second largest sepsis driven T2Dx® Instrument order LEXINGTON, Mass., August 7, 2023 (GLOBE NEWSWIRE)—T2 Biosystems, Inc. (NASDAQ:TTOO) (the “Company”), a leader in the rapid detection

August 9, 2023 EX-99

T2 Biosystems Regains Compliance with Nasdaq’s Market Value of Listed Securities Requirement

EX-99 Exhibit 99.1 T2 Biosystems Regains Compliance with Nasdaq’s Market Value of Listed Securities Requirement LEXINGTON, Mass., August 9, 2023 (GLOBE NEWSWIRE) — T2 Biosystems, Inc. (NASDAQ:TTOO) (the “Company”), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today announced that it received written notice from the NASDAQ Stock Market LLC (“NASDAQ”)

August 9, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 8, 2023 T2 BIOSYSTEMS, INC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 8, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File

August 8, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-36571 T2 Biosyst

July 31, 2023 EX-99.1

T2 Biosystems Receives Extension to Comply with Nasdaq Listing Requirements

EX-99.1 Exhibit 99.1 T2 Biosystems Receives Extension to Comply with Nasdaq Listing Requirements LEXINGTON, Mass., July 31, 2023 (GLOBE NEWSWIRE) — T2 Biosystems, Inc. (NASDAQ:TTOO), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, announced today that the Nasdaq Hearings Panel (the “Panel”) has granted the Company’s request for an extension through Nove

July 31, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 27, 2023 T2 BIOSYSTEMS, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 27, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File

July 26, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Ame

DEF 14A Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

July 20, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 20, 2023 T2 BIOSYSTEMS, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 20, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File

July 20, 2023 EX-99.1

T2 Biosystems Receives FDA Breakthrough Device Designation for

EX-99.1 Exhibit 99.1 FOR IMMEDIATE RELEASE T2 Biosystems Receives FDA Breakthrough Device Designation for Candida Auris Diagnostic Test LEXINGTON, Mass., July 20, 2023 (GLOBE NEWSWIRE)—T2 Biosystems, Inc. (NASDAQ:TTOO), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, announced today the U.S. Food and Drug Administration (FDA) has granted Breakthrough De

July 13, 2023 SC 13G

US89853L2034 / T2 Biosystems Inc / CR Group L.P. - SC 13G Passive Investment

SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* T2 Biosystems, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 89853L203 (CUSIP Number) July 3, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the ru

July 13, 2023 EX-99.A

JOINT FILING AGREEMENT

EX-99.A CUSIP No. 89853L203 Page 1 4 of 14 EXHIBIT A JOINT FILING AGREEMENT In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the undersigned agree to the joint filing on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the Common Stock of T2 Biosystems, Inc. and further agree that this agreement be included

July 12, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 12, 2023 T2 BIOSYSTEMS, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 12, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File

July 12, 2023 424B5

Up to $65,000,000 Common Stock

424B5 Table of Contents Filed pursuant to Rule 424(b)(5) Registration No. 333- 254918 AMENDMENT NO. 1 DATED JULY 12, 2023 To Prospectus Supplement dated April 9, 2021 and Prospectus dated April 9, 2021 Up to $65,000,000 Common Stock This Amendment No. 1 to Prospectus Supplement, or this amendment, amends our prospectus supplement dated April 9, 2021, or the prospectus supplement. This amendment sh

July 12, 2023 EX-99.1

T2 Biosystems Announces Preliminary Second Quarter 2023 Financial Results Received record quarterly sepsis test panel orders and strengthened balance sheet

EX-99.1 Exhibit 99.1 T2 Biosystems Announces Preliminary Second Quarter 2023 Financial Results Received record quarterly sepsis test panel orders and strengthened balance sheet LEXINGTON, Mass., July 12, 2023 (GLOBE NEWSWIRE)—T2 Biosystems, Inc. (NASDAQ:TTOO), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today announced preliminary unaudited financia

July 12, 2023 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Ame

PRE 14A Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

July 6, 2023 EX-3.1

Certificate of Designation of Preferences, Rights and Limitations of Series A Preferred Stock (incorporated by reference to Exhibit 3.1 of the Company’s Form 8-K (File No. 001-36571) filed on July 6, 2023)

EX-3.1 Exhibit 3.1 T2 BIOSYSTEMS, INC. CERTIFICATE OF DESIGNATION OF PREFERENCES, RIGHTS AND LIMITATIONS OF SERIES A PREFERRED STOCK Pursuant to Section 151 of the General Corporation Law of the State of Delaware THE UNDERSIGNED DOES HEREBY CERTIFY, on behalf of T2 BIOSYSTEMS, INC., a Delaware corporation (the “Corporation”), that the following resolution was duly adopted by the board of directors

July 6, 2023 EX-10.1

Purchase Agreement, dated July 5, 2023, by and between the Company and the Purchasers party thereto (incorporated by reference to Exhibit 10.1 of the Company’s Form 8-K (File No. 001-36571) filed on November 15, 2023) filed on July 6, 2023

EX-10.1 Exhibit 10.1 Execution Version PURCHASE AGREEMENT THIS PURCHASE AGREEMENT (this “Agreement”) is made as of July 5, 2023, by and among CRG Partners III L.P., CRG Partners III - Parallel Fund “A” L.P., CRG Partners III (Cayman) Unlev AIV I L.P., CRG Partners III (Cayman) Lev AIV I L.P., and CRG Partners III Parallel Fund “B” (Cayman) L.P. (each, a “Purchaser” and collectively, the “Purchaser

July 6, 2023 EX-3.2

Certificate of Designation of Preferences, Rights and Limitations of Series B Convertible Preferred Stock (incorporated by reference to Exhibit 3.2 of the Company’s Form 8-K (File No. 001-36571) filed on July 6, 2023)

EX-3.2 Exhibit 3.2 T2 BIOSYSTEMS, INC. CERTIFICATE OF DESIGNATION OF PREFERENCES, RIGHTS AND LIMITATIONS OF SERIES B CONVERTIBLE PREFERRED STOCK PURSUANT TO SECTION 151 OF THE DELAWARE GENERAL CORPORATION LAW T2 BIOSYSTEMS, INC., Delaware corporation (the “Corporation”), in accordance with the provisions of Section 103 of the Delaware General Corporation Law (the “DGCL”) does hereby certify that,

July 6, 2023 EX-10.2

Securities Purchase Agreement, dated July 3, 2023, by and between the Company and the Lenders party thereto (incorporated by reference to Exhibit 10.2 of the Company’s Form 8-K (File No. 001-36571) filed on November 15, 2023) filed on July 6, 2023

EX-10.2 Exhibit 10.2 Execution Version SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is made as of July 3, 2023, by and among CRG Partners III L.P., CRG Partners III - Parallel Fund “A” L.P., CRG Partners III (Cayman) Unlev AIV I L.P., CRG Partners III (Cayman) Lev AIV I L.P. and CRG Partners III Parallel Fund “B” (Cayman) L.P. (together, “CRG” or the “Purchas

July 6, 2023 EX-10.3

Consent to Term Loan Agreement, dated July 3, 2023, by and between the Company and CRG Servicing LLC, as administrative agent and collateral agent, and the lenders party thereto

Exhibit 10.3 EXECUTION VERSION CONSENT TO TERM LOAN AGREEMENT THIS CONSENT TO TERM LOAN AGREEMENT, dated as of July 3, 2023 (this “Consent”) is made among T2 BIOSYSTEMS, INC., a Delaware corporation (“Borrower”), the other Obligors party hereto, CRG SERVICING LLC, as administrative agent and collateral agent (in such capacities, “Administrative Agent”) and the lenders listed on the signature pages

July 6, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 3, 2023 T2 BIOSYSTEMS, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 3, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File N

June 30, 2023 SC 13G

US89853L2034 / T2 Biosystems Inc / GSA CAPITAL PARTNERS LLP Passive Investment

Securities and Exchange Commission, Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.)* (Name of Issuer) : T2 Biosystems Ord (Title of Class of Securities) : Common Stock (CUSIP Number) : 89853L2034 (Date of Event Which Requires Filing of this Statement) : 06/28/2023 Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

June 23, 2023 SC 13G

US89853L2034 / T2 Biosystems Inc / Carrick Jason Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* T2 Biosystems, Inc. (Name of Issuer) Com New (Title of Class of Securities) 89853L203 (CUSIP Number) June 15, 2023 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is f

June 23, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 20, 2023 T2 BIOSYSTEMS, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 20, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File

June 22, 2023 SC 13G

US89853L2034 / T2 Biosystems Inc / Markey John - 13G FILING Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* T2 Biosystems, Inc. (Name of Issuer) COM NEW (Title of Class of Securities) 89853L203 (CUSIP Number) June 22, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is

June 16, 2023 SC 13G

US89853L2034 / T2 Biosystems Inc / Markey John - 13G FILING Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* T2 Biosystems, Inc. (Name of Issuer) COM NEW (Title of Class of Securities) 89853L203 (CUSIP Number) June 16, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is

June 14, 2023 SC 13G

US89853L2034 / T2 Biosystems Inc / Markey John - 13G FILING Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* T2 Biosystems, Inc. (Name of Issuer) COM NEW (Title of Class of Securities) 89853L203 (CUSIP Number) June 14, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is

June 12, 2023 SC 13G

US89853L2034 / T2 Biosystems Inc / Markey John - 13G FILING Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* T2 Biosystems, Inc. (Name of Issuer) COM NEW (Title of Class of Securities) 89853L203 (CUSIP Number) June 12, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is

June 9, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 9, 2023 T2 BIOSYSTEMS, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 9, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File N

June 9, 2023 424B5

Up to $8,871,000 Common Stock

424B5 As Filed Pursuant to Rule 424(b)(5) Registration No. 333-254918 PROSPECTUS SUPPLEMENT (To Prospectus Supplements dated April 9, 2021, May 22, 2023, May 30, 2022 and June 5, 2023) and Prospectus dated April 9, 2021) Up to $8,871,000 Common Stock This Prospectus Supplement supplements the prospectus supplements, dated April 9, 2021, May 22, 2023, May 30, 2023 and June 5, 2023 (collectively, th

June 9, 2023 EX-99.1

T2 Biosystems Announces Clinical Collaboration with Vanderbilt University Medical Center to Implement and Evaluate the T2Bacteria Panel for Clinical Use

EX-99.1 Exhibit 99.1 T2 Biosystems Announces Clinical Collaboration with Vanderbilt University Medical Center to Implement and Evaluate the T2Bacteria Panel for Clinical Use LEXINGTON, Mass., June 9, 2023 (GLOBE NEWSWIRE)—T2 Biosystems, Inc. (NASDAQ:TTOO), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today announced a collaborative relationship with

June 5, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 5, 2023 T2 BIOSYSTEMS, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 5, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File N

June 5, 2023 EX-99.1

T2 Biosystems Announces Submission for FDA Breakthrough Device Designation for

EX-99.1 Exhibit 99.1 FOR IMMEDIATE RELEASE T2 Biosystems Announces Submission for FDA Breakthrough Device Designation for Candida Auris Diagnostic Test Company plans to add multidrug-resistant Candida auris detection to its FDA-cleared T2Candida Panel LEXINGTON, Mass., June 5, 2023 (GLOBE NEWSWIRE)—T2 Biosystems, Inc. (NASDAQ:TTOO), a leader in the rapid detection of sepsis-causing pathogens and a

June 5, 2023 424B5

Up to $5,392,000 Common Stock

424B5 As Filed Pursuant to Rule 424(b)(5) Registration No. 333-254918 PROSPECTUS SUPPLEMENT (To Prospectus Supplements dated April 9, 2021, May 22, 2023 and May 30, 2022 and Prospectus dated April 9, 2021) Up to $5,392,000 Common Stock This Prospectus Supplement supplements the prospectus supplements, dated April 9, 2021, May 22, 2023 and May 30, 2023 (collectively, the “ATM Prospectus Supplement”

May 30, 2023 EX-99.1

T2 Biosystems Announces Second Largest Sepsis-Driven Instrument Sale in Company History

EX-99.1 2 d423227dex991.htm EX-99.1 Exhibit 99.1 T2 Biosystems Announces Second Largest Sepsis-Driven Instrument Sale in Company History LEXINGTON, Mass., May 30, 2023 (GLOBE NEWSWIRE)—T2 Biosystems, Inc. (NASDAQ:TTOO), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today announced the second largest sale of sepsis-driven T2Dx® Instruments in Company h

May 30, 2023 424B5

Up to $2,824,000 Common Stock

424B5 As Filed Pursuant to Rule 424(b)(5) Registration No. 333-254918 PROSPECTUS SUPPLEMENT (To Prospectus Supplements dated April 9, 2021 and May 22, 2023 and Prospectus dated April 9, 2021) Up to $2,824,000 Common Stock This Prospectus Supplement supplements the prospectus supplements, dated April 9, 2021 and May 22, 2023 (collectively, the “ATM Prospectus Supplement”), relating to the offer and

May 30, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 30, 2023 T2 BIOSYSTEMS, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 30, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File N

May 25, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 23, 2023 T2 BIOSYSTEMS, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 23, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File N

May 25, 2023 EX-99.1

T2 BIOSYSTEMS, INC. CONDENSED CONSOLIDATED BALANCE SHEETS (In thousands, except share and per share data) March 31, 2023 December 31, 2022 Assets Current assets: Cash and cash equivalents $ 10,117 $ 10,329 Accounts receivable 1,323 2,163 Inventories

EX-99.1 Exhibit 99.1 T2 Biosystems Announces First Quarter 2023 Financial Results Filed FDA submission for T2Biothreat Panel, implemented a restructuring program and announced exploration of strategic alternatives LEXINGTON, Mass., May 23, 2023 (GLOBE NEWSWIRE)—T2 Biosystems, Inc. (NASDAQ:TTOO) (the “Company”), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance g

May 25, 2023 EX-99.2

1

EX-99.2 Exhibit 99.2 T2 Biosystems 1Q May 23, 2023 Trip Taylor, IR Thank you, operator. I would like to remind everyone that comments made by management today and answers to questions will include forward-looking statements. Those include statements related to T2 Biosystems’ future financial and operating results and plans for developing and marketing new products. Forward-looking statements are b

May 23, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 23, 2023 T2 BIOSYSTEMS, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 23, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File N

May 22, 2023 EX-10.1

Amendment of Solicitation/Modification of Contract, dated as of May 1, 2023 by and between the Company and Biomedical Advanced Research and Development Authority of the U.S. Department of Health and Human Services (incorporated by reference to Exhibit 10.1 of the Company’s Form 10-Q (File No. 001-36571) filed on May 22, 2023)

Exhibit 10.1 [****] = Certain confidential information contained in this document, marked by brackets, has been omitted because it is both (i) not material and (ii) would be competitively harmful if publicly disclosed. AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT 1. CONTRACT ID CODE PAGE OF PAGES 1 6 2. AMENDMENT/MODIFICATION NO. P00013 3. EFFECTIVE DATE See Block 16C 4. REQUISITION/PURCHASE

May 22, 2023 EX-10.2

Waiver and Consent to Term Loan Agreement with CRG Servicing LLC, dated May 19, 2023 (incorporated by reference to Exhibit 10.2 of the Company’s Form 10-Q (File No. 001-36571) filed on May 22, 2023)

Exhibit 10.2 WAIVER AND CONSENT THIS WAIVER AND CONSENT, dated as of May 19, 2023 (this “Waiver”), is made among T2 BIOSYSTEMS, INC., a Delaware corporation (“Borrower”), CRG SERVICING LLC, as administrative agent and collateral agent (in such capacities, “Administrative Agent”) and the lenders listed on the signature pages hereof under the heading “LENDERS” (each, a “Lender” and, collectively, th

May 22, 2023 424B5

Up to $4,200,000 Common Stock

424B5 As Filed Pursuant to Rule 424(b)(5) Registration No. 333-254918 PROSPECTUS SUPPLEMENT (To Prospectus and the Prospectus Supplement dated April 9, 2021) Up to $4,200,000 Common Stock This Prospectus Supplement supplements the prospectus supplement, dated April 9, 2021 (the “ATM Prospectus Supplement”), relating to the offer and sale of shares of our common stock, $0.001 par value per share, h

May 22, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-36571 T2 Biosys

May 15, 2023 NT 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 12b-25 NOTIFICATION OF LATE FILING (Check One): ☐ Form 10-K ☐ Form 20-F ☐ Form 11-K ☒ Form 10-Q ☐ Form 10-D ☐ Form N-CEN ☐ Form N-CSR For Period Ended: March 31, 2023 ☐ Transi

NT 10-Q SEC FILE NUMBER: 001-36571 CUSIP NUMBER: 89853L203 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 12b-25 NOTIFICATION OF LATE FILING (Check One): ☐ Form 10-K ☐ Form 20-F ☐ Form 11-K ☒ Form 10-Q ☐ Form 10-D ☐ Form N-CEN ☐ Form N-CSR For Period Ended: March 31, 2023 ☐ Transition Report on Form 10-K ☐ Transition Report on Form 20-F ☐ Transition Report on Form 11-K ☐ Transition Report on Form 10-Q For the Transition Period Ended: Read Instructions (on back page) Before Preparing Form.

March 31, 2023 EX-10

Amendment No. 7 to Term Loan Agreement, dated February 15, 2022, between T2 Biosystems, Inc. and CRG Servicing LLC (incorporated by reference to Exhibit 10.56 of the Company’s Form 10-K (File No. 001-36571) filed on March 31, 2023)

Exhibit 10.56 Execution Version AMENDMENT No. 7 TO TERM LOAN AGREEMENT THIS AMENDMENT NO. 7 TO TERM LOAN AGREEMENT, dated as of February 15, 2022 (this “Amendment”) is made among T2 BIOSYSTEMS, INC., a Delaware corporation (“Borrower”), the other Obligors party hereto, CRG SERVICING LLC, as administrative agent and collateral agent (in such capacities, “Administrative Agent”) and the lenders liste

March 31, 2023 EX-10

Change of Control Severance Agreement, dated March 21, 2022 by and between the Company and Michael Gibbs (incorporated by reference to Exhibit 10.54 of the Company’s Form 10-K (File No. 001-36571) filed on March 31, 2023)

Exhibit 10.54 March 21, 2022 Michael Gibbs [*******] [*******] Dear Michael, This letter sets forth the agreement between you and T2 Biosystems, Inc. (the “Company”) regarding certain terms and conditions of your employment. This replaces any prior agreement between yourself and the Company with respect to the subject matter contained herein. You are entitled to receive the following: 1. Severance

March 31, 2023 EX-10

Letter Agreement, dated March 30, 2023, by and between T2 Biosystems, Inc. and John Sprague

Exhibit 10.67 March 30, 2023 John Sprague Re: Retention Bonus Dear John, T2 Biosystems, Inc. (the “Company” or “T2”) is pleased to inform you that you are eligible to earn a special, one-time retention bonus (the “Retention Bonus”) in the total aggregate amount of $80,000, to be paid in two installments of $40,000, pursuant to the terms and conditions set forth in this letter agreement. Subject to

March 31, 2023 EX-10

Letter Agreement, dated March 30, 2023, by and between T2 Biosystems, Inc. and Brett Giffin

EX-10 14 ttoo-ex1069.htm EX-10.69 Exhibit 10.69 March 30, 2023 Brett Giffin Re: Retention Bonus Dear Brett, T2 Biosystems, Inc. (the “Company” or “T2”) is pleased to inform you that you are eligible to earn a special, one-time retention bonus (the “Retention Bonus”) in the total aggregate amount of $80,000, to be paid in two installments of $40,000, pursuant to the terms and conditions set forth i

March 31, 2023 EX-10

Employment Offer Letter, dated as of November 2, 2021, by and between the Company and Brett Giffin (incorporated by reference to Exhibit 10.52 of the Company’s Form 10-K (File No. 001-36571) filed on March 31, 2023)

Exhibit 10.52 November 2, 2021 Brett Giffin [*******] [*******] Dear Brett: On behalf of T2 Biosystems, Inc., (the "Company") I am delighted to make this offer of employment to you to join us in the role of Chief Commercial Officer for the Company beginning on November 8, 2021. At T2 Biosystems, a leader in the detection of sepsis causing pathogens, our mission is to save lives and improve healthc

March 31, 2023 EX-10

T2 Biosystems, Inc. Inducement Award Plan (as amended and restated, effective February 16, 2023) and form of option agreement, restricted stock agreement, and restricted stock unit agreement thereunder (incorporated by reference to Exhibit 10.51 of the Company’s Form 10-K (File No. 001-36571) filed on March 31, 2023)

Exhibit 10.51 T2 BIOSYSTEMS, INC. INDUCEMENT AWARD PLAN (as amended and restated effective February 16, 2023) ARTICLE 1. PURPOSE The purpose of the T2 Biosystems, Inc. Inducement Award Plan (as it may be amended or restated from time to time, the “Plan”) is to promote the success and enhance the value of T2 Biosystems, Inc. (the “Company”) by linking the individual interests of eligible individual

March 31, 2023 EX-4

Description of Securities

Exhibit 4.4 DESCRIPTION OF THE REGISTRANT’S SECURITIES REGISTERED UNDER SECTION 12 OF THE EXCHANGE ACT General As of December 31, 2022, T2 Biosystems, Inc. had one class of securities registered under Section 12 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). References herein to “we,” “us,” “our” and the “Company” refer to T2 Biosystems, Inc. and not to any of its subsidi

March 31, 2023 EX-10

Waiver, dated January 23, 2023 to that certain Term Loan Agreement, dated as of December 30, 2016, by and among the Company, CRG Servicing LLC, as administrative agent and collateral agent incorporated by reference to Exhibit 10.66 of the Company’s Form 10-K (File No. 001-36571) filed on March 31, 2023)

Exhibit 10.66 Execution Version WAIVER THIS WAIVER, dated as of January 23, 2023 (this “Waiver”) is made among T2 BIOSYSTEMS, INC., a Delaware corporation (“Borrower”), CRG SERVICING LLC, as administrative agent and collateral agent (in such capacities, “Administrative Agent”) and the lenders listed on the signature pages hereof under the heading “LENDERS” (each, a “Lender” and, collectively, the

March 31, 2023 EX-10

Letter Agreement, dated March 30, 2023, by and between T2 Biosystems, Inc. and Michael Gibbs

Exhibit 10.68 March 30, 2023 Michael Gibbs Re: Retention Bonus Dear Michael, T2 Biosystems, Inc. (the “Company” or “T2”) is pleased to inform you that you are eligible to earn a special, one-time retention bonus (the “Retention Bonus”) in the total aggregate amount of $80,000, to be paid in two installments of $40,000, pursuant to the terms and conditions set forth in this letter agreement. Subjec

March 31, 2023 EX-10

Change of Control Severance Agreement, dated March 21, 2022 by and between the Company and John Sprague (incorporated by reference to Exhibit 10.53 of the Company’s Form 10-K (File No. 001-36571) filed on March 31, 2023)

Exhibit 10.53 March 21, 2022 John Sprague [*******] [*******] Dear John, This letter sets forth the agreement between you and T2 Biosystems, Inc. (the “Company”) regarding certain terms and conditions of your employment. This replaces any prior agreement between yourself and the Company with respect to the subject matter contained herein. You are entitled to receive the following: 1. Severance Com

March 31, 2023 EX-10

Amendment of Solicitation/Modification of Contract, dated as of March 20, 2023 by and between the Company and Biomedical Advanced Research and Development Authority of the U.S. Department of Health and Human Services

Exhibit 10.65 AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT 1. CONTRACT ID CODE PAGE OF PAGES 1 7 2. AMENDMENT/MODIFICATION NO. P00012 3. EFFECTIVE DATE See Block 16C 4. REQUISITION/PURCHASE REQ. NO. 5. PROJECT NO. (If applicable) 6. ISSUED BY CODE ASPR-BARDA 7. ADMINISTERED BY (If other than Item 6) CODE ASPR-BARDA ASPR-BARDA ASPR-BARDA 200 Independence Ave., S.W. Room 640-G Washington DC 20

March 31, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 31, 2023 T2 BIOSYSTEMS, INC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 31, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File

March 31, 2023 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the year ended December 31, 2022 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-36571 T2 Biosystems, Inc. (Exa

March 31, 2023 EX-10

Amendment No. 6 to Commercial Lease between Columbus Day Realty, Inc. and T2 Biosystems, Inc. dated September 26, 2022 (incorporated by reference to Exhibit 10.64 of the Company’s Form 10-K (File No. 001-36571) filed on March 31, 2023)

Exhibit 10.64 AMENDMENT NO. 6 TO COMMERCIAL LEASE BETWEEN COLUMBUS DAY REALTY, INC. AND T2 BIOSYSTEMS, INC. This Amendment No. 6 is to a Commercial Lease dated May 6, 2013, by and between Columbus Day Realty, Inc. (LESSOR), and T2 Biosystems, Inc. (LESSEE), which lease relates to the premises at 231 Andover Street, Wilmington, Massachusetts. WHEREAS, the Commercial Lease is dated May 6, 2013; WHER

March 31, 2023 EX-10

Change of Control Severance Agreement, dated March 21, 2022 by and between the Company and Brett Giffin (incorporated by reference to Exhibit 10.55 of the Company’s Form 10-K (File No. 001-36571) filed on March 31, 2023)

Exhibit 10.55 March 21, 2022 Brett Giffin [*******] [*******] Dear Brett, This letter sets forth the agreement between you and T2 Biosystems, Inc. (the “Company”) regarding certain terms and conditions of your employment. This replaces any prior agreement between yourself and the Company with respect to the subject matter contained herein. You are entitled to receive the following: 1. Severance Co

March 31, 2023 EX-21

Subsidiaries of the Registrant.

Exhibit 21.1 Subsidiaries of T2 Biosystems, Inc.: Name Jurisdiction of Organization T2 Biosystems Securities Corporation Massachusetts

March 16, 2023 EX-99.2

1

EX-99.2 Exhibit 99.2 T2 Biosystems 4Q March 13, 2023 Regan Talley, IR Thank you, operator. I would like to remind everyone that comments made by management today and answers to questions will include forward-looking statements. Those include statements related to T2 Biosystems’ future financial and operating results and plans for developing and marketing new products. Forward-looking statements ar

March 16, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 13, 2023 T2 BIOSYSTEMS, INC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 13, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission File

March 16, 2023 EX-99.1

T2 Biosystems, Inc. Consolidated Balance Sheets (In thousands, except share and per share data) December 31, December 31, 2022 2021 Assets Current assets: Cash and cash equivalents $ 10,329 $ 22,245 Marketable securities — 9,996 Accounts receivable 2

EX-99.1 2 d487064dex991.htm EX-99.1 Exhibit 99.1 T2 Biosystems Announces Fourth Quarter and Full Year 2022 Financial Results Achieved record sepsis product revenue and sepsis-driven T2Dx Instrument placements in 2022 LEXINGTON, Mass., March 13, 2023 (GLOBE NEWSWIRE)—T2 Biosystems, Inc. (NASDAQ:TTOO) (the “Company”), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resista

February 21, 2023 SC 13G

US89853L2034 / T2 Biosystems Inc / Lind Global Fund II LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* T2 Biosystems, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 89853L203 (CUSIP Number) February 17, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule

February 21, 2023 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 2 exhibit99-1.htm JOINT FILING AGREEMENT BY AND AMONG THE REPORTING PERSONS Exhibit 99.1 JOINT FILING AGREEMENT The undersigned hereby agree that a single Schedule 13G (or any amendment thereto) relating to the Common Stock, par value $0.001 per share, of T2 Biosystems, Inc. shall be filed on behalf of each of the undersigned and that this Agreement shall be filed as an exhibit to such Sch

February 16, 2023 EX-1.1

Underwriting Agreement, dated February 14, 2023, between T2 Biosystems, Inc. and Craig-Hallum Capital Group, LLC, as representatives of the several underwriters named therein.

EX-1.1 Exhibit 1.1 9,018,519 SHARES OF COMMON STOCK 22,222,222 COMMON WARRANTS (EXERCISABLE FOR 22,222,222 WARRANT SHARES) AND 2,092,592 PRE-FUNDED WARRANTS (EXERCISABLE FOR 2,092,592 WARRANT SHARES) T2 BIOSYSTEMS, INC. UNDERWRITING AGREEMENT February 14, 2023 Craig-Hallum Capital Group LLC As the Representative of the Several underwriters, if any, named in Schedule I hereto 222 South Ninth Street

February 16, 2023 EX-4.1

Pre-Funded Common Stock Purchase Warrant (incorporated by reference to Exhibit 4.1 of the Company’s Form 8-K (File No. 001-36571) filed on February 16, 2023)

EX-4.1 Exhibit 4.1 PRE-FUNDED COMMON STOCK PURCHASE WARRANT T2 BIOSYSTEMS, INC. Warrant Shares: Initial Exercise Date: February 17, 2023 THIS PRE-FUNDED COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or afte

February 16, 2023 424B5

9,018,519 Shares of Common Stock Warrants to Purchase up to 22,222,222 Shares of Common Stock Pre-funded Warrants to Purchase up to 2,092,592 Shares of Common Stock

424B5 Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-254918 PROSPECTUS SUPPLEMENT (To Prospectus dated April 9, 2021) 9,018,519 Shares of Common Stock Warrants to Purchase up to 22,222,222 Shares of Common Stock Pre-funded Warrants to Purchase up to 2,092,592 Shares of Common Stock We are offering 9,018,519 shares of common stock, pre-funded warrants to purchase 2,092,592

February 16, 2023 EX-4.2

Common Stock Purchase Warrant (incorporated by reference to Exhibit 4.2 of the Company’s Form 8-K (File No. 001-36571) filed on February 16, 2023)

EX-4.2 4 d426940dex42.htm EX-4.2 Exhibit 4.2 COMMON STOCK PURCHASE WARRANT T2 BIOSYSTEMS, INC. Warrant Shares: Initial Exercise Date: February 17, 2023 THIS COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or

February 16, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 14, 2023 T2 BIOSYSTEMS,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 14, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission F

February 13, 2023 424B5

Subject to Completion, Dated February 13, 2023

424B5 Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-254918 The information in this preliminary prospectus supplement and the accompanying prospectus, relating to an effective registration statement under the Securities Act of 1933, as amended, is not complete and may be changed. This preliminary prospectus supplement and the accompanying prospectus are not an offer to sel

February 13, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 13, 2023 T2 BIOSYSTEMS,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 13, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission F

January 23, 2023 EX-99.1

T2 Biosystems Announces Preliminary Fourth Quarter and Full Year 2022 Financial Results Achieved record sepsis product revenue and sepsis-driven T2Dx Instrument units in 2022

EX-99.1 Exhibit 99.1 T2 Biosystems Announces Preliminary Fourth Quarter and Full Year 2022 Financial Results Achieved record sepsis product revenue and sepsis-driven T2Dx Instrument units in 2022 LEXINGTON, Mass., January 23, 2023 (GLOBE NEWSWIRE)—T2 Biosystems, Inc. (NASDAQ:TTOO), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today announced prelimin

January 23, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 17, 2023 T2 BIOSYSTEMS, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 17, 2023 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fi

November 25, 2022 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 22, 2022 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission F

November 14, 2022 EX-10.5

Amendment No. 8 to Term Loan Agreement, dated November 10, 2022, between T2 Biosystems, Inc. and CRG Servicing LLC (incorporated by reference to Exhibit 10.5 of the Company’s Form 10-Q (File No. 001-36571) filed on November 14, 2022)

Exhibit 10.5 AMENDMENT No. 8 TO TERM LOAN AGREEMENT THIS AMENDMENT NO. 8 TO TERM LOAN AGREEMENT, dated as of November 10, 2022 (this ?Amendment?) is made among T2 BIOSYSTEMS, INC., a Delaware corporation (?Borrower?), the other Obligors party hereto, CRG SERVICING LLC, as administrative agent and collateral agent (in such capacities, ?Administrative Agent?) and the lenders listed on the signature

November 14, 2022 EX-10.4

Amendment of Solicitation/Modification of Contract, dated as of September 29, 2022 by and between the Company and Biomedical Advanced Research and Development Authority of the U.S. Department of Health and Human Services

EXHIBIT 10.4 AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT 1. CONTRACT ID CODE PAGE OF PAGE 1 ? 53 2. AMENDMENT/MODIFICATION NO. P000l0 3. EFFECTIVE DATE See Block 16C 6. ISSUED BY CODE ASPR-BARDA 200 Independence Ave., S.W. Room 640-G Washington DC 20201 [****] = Certain confidential information contained in this document, marked by brackets, has been omitted because it is both (i) not mater

November 14, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-36571 T2 Bi

November 10, 2022 EX-99.1

T2 BIOSYSTEMS, INC. CONDENSED CONSOLIDATED BALANCE SHEETS (In thousands, except share and per share data) September 30, 2022 December 31, 2021 Assets Current assets: Cash and cash equivalents $ 20,366 $ 22,245 Marketable securities — 9,996 Accounts r

Exhibit 99.1 T2 Biosystems Announces Third Quarter 2022 Financial Results Achieves record quarterly sepsis and related revenue and advances product pipeline LEXINGTON, Mass., November 10, 2022 (GLOBE NEWSWIRE)?T2 Biosystems, Inc. (NASDAQ:TTOO) (the ?Company?), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today announced financial results for the thir

November 10, 2022 EX-99.2

1

Exhibit 99.2 T2 Biosystems 3Q November 10, 2022 Philip Taylor Thank you, operator. I would like to remind everyone that comments made by management today and answers to questions will include forward-looking statements. Those include statements related to T2 Biosystems? future financial and operating results and plans for developing and marketing new products. Forward-looking statements are based

November 10, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2022 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission F

November 7, 2022 EX-99.1

HHS and the Cohen Foundation Name T2 Biosystems a Phase 1 Winner in LymeX Diagnostics Prize

EX-99.1 Exhibit 99.1 HHS and the Cohen Foundation Name T2 Biosystems a Phase 1 Winner in LymeX Diagnostics Prize LEXINGTON, Mass., November 7, 2022 (GLOBE NEWSWIRE) — T2 Biosystems, Inc. (NASDAQ:TTOO) a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, announced today that the U.S. Department of Health and Human Services (“HHS”) and the Steven & Alexandra C

November 7, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 20, 2022 T2 BIOSYSTEMS, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 20, 2022 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fi

October 14, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 14, 2022 T2 BIOSYSTEMS, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 14, 2022 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fi

October 14, 2022 EX-99.1

T2 Biosystems Highlights Multiple New Studies Demonstrating Improved Rapid Detection Across Several Patient Populations Studies demonstrate that T2Bacteria and T2Candida panels enable sensitive and specific diagnosis to enhance the standard of care

EX-99.1 Exhibit 99.1 T2 Biosystems Highlights Multiple New Studies Demonstrating Improved Rapid Detection Across Several Patient Populations Studies demonstrate that T2Bacteria and T2Candida panels enable sensitive and specific diagnosis to enhance the standard of care LEXINGTON, Mass., October 14, 2022 (GLOBE NEWSWIRE)—T2 Biosystems, Inc. (NASDAQ:TTOO), a leader in the rapid detection of sepsis-c

October 13, 2022 EX-99.1

T2 Biosystems Announces Plan to Commercialize a Diagnostic Test for Early Lyme Disease Plans to Initiate Marketing and Sales in the U.S. as a Laboratory Developed Test in 2023

EX-99.1 Exhibit 99.1 T2 Biosystems Announces Plan to Commercialize a Diagnostic Test for Early Lyme Disease Plans to Initiate Marketing and Sales in the U.S. as a Laboratory Developed Test in 2023 LEXINGTON, Mass., October 13, 2022 (GLOBE NEWSWIRE) — T2 Biosystems, Inc. (NASDAQ:TTOO) a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, announced today plans

October 13, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 13, 2022 T2 BIOSYSTEMS, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 13, 2022 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fi

October 12, 2022 EX-99.2

T2 Biosystems Announces Reverse Stock Split Effective Today

EX-99.2 Exhibit 99.2 T2 Biosystems Announces Reverse Stock Split Effective Today TTOO common stock expected to begin trading on a split-adjusted basis on October 13, 2022 LEXINGTON, Mass., October 12, 2022 (GLOBE NEWSWIRE) — T2 Biosystems, Inc. (NASDAQ:TTOO) (the “Company”), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today announced that the Compan

October 12, 2022 EX-99.1

T2 Biosystems Announces Preliminary Third Quarter 2022 Financial Results and Updates 2022 Financial Outlook

EX-99.1 Exhibit 99.1 T2 Biosystems Announces Preliminary Third Quarter 2022 Financial Results and Updates 2022 Financial Outlook LEXINGTON, Mass., October 12, 2022 (GLOBE NEWSWIRE)—T2 Biosystems, Inc. (NASDAQ:TTOO) (the “Company”), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today announced preliminary unaudited financial results for the third quart

October 12, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 11, 2022 T2 BIOSYSTEMS, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 11, 2022 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fi

October 12, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 12, 2022 T2 BIOSYSTEMS, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 12, 2022 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fi

October 12, 2022 EX-3.1

Certificate of Amendment of Restated Certificate of Incorporation of the Company dated October 12, 2022 (incorporated by reference to Exhibit 3.1 of the Company’s Form 8-K (File No. 001-36571) filed on October 12, 2022)

EX-3.1 Exhibit 3.1 CERTIFICATE OF AMENDMENT OF RESTATED CERTIFICATE OF INCORPORATION OF T2 BIOSYSTEMS, INC. T2 Biosystems, Inc., a corporation organized and existing under and by virtue of the General Corporation Law of the State of Delaware (the “Company”), does hereby certify as follows: FIRST: That, the Board of Directors of the Company duly adopted resolutions by unanimous written consent in a

September 30, 2022 8-K

Entry into a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 26, 2022 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission

September 30, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Ame

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? ? Preliminary Proxy Statement ? Confidential, for Use of the Commi

September 30, 2022 8-K

Entry into a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 29, 2022 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission

August 30, 2022 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report: August 24, 2022 (Date of earliest event reported) T2 Biosystems, Inc. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fil

August 26, 2022 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confid

August 26, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of

August 17, 2022 EX-99.2

1

Exhibit 99.2 T2 Biosystems 2Q August 15, 2022 Emma Poalillo Thank you, operator. I would like to remind everyone that comments made by management today and answers to questions will include forward-looking statements. Those include statements related to T2 Biosystems? future financial and operating results and plans for developing and marketing new products. Forward-looking statements are based on

August 17, 2022 EX-99.1

T2 Biosystems, Inc. Consolidated Balance Sheets (In thousands, except share and per share data) June 30, 2022 December 31, 2021 Assets Current assets: Cash and cash equivalents $ 13,212 $ 22,245 Marketable securities — 9,996 Accounts receivable 2,721

Exhibit 99.1 T2 Biosystems Announces Second Quarter 2022 Financial Results T2Dx Instrument contracts increased by 300% compared to the prior year period LEXINGTON, Mass., August 15, 2022 (GLOBE NEWSWIRE)?T2 Biosystems, Inc. (NASDAQ:TTOO) (the ?Company?), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, today announced financial results for the second qua

August 17, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 15, 2022 T2 BIOSYSTEMS, INC. (Exact name of registrant as specified in its charter) Delaware 001-36571 20-4827488 (State or other jurisdiction of incorporation) (Commission Fil

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