IMRX / Immuneering Corporation - Документы SEC, Годовой отчет, Доверенное заявление

Иммунерная корпорация
US ˙ NasdaqGM ˙ US45254E1073

Основная статистика
CIK 1790340
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Immuneering Corporation
SEC Filings (Chronological Order)
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September 3, 2025 EX-FILING FEES

Security Type

Calculation of Filing Fee Tables S-3 Immuneering Corp Table 1: Newly Registered and Carry Forward Securities ☐Not Applicable Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forward Form Type Carry Forward File Number Carry Forward Initial Effective Date Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward Newly Registered Securities Fees to be Paid 1 Equity Common Stock, $0.

September 3, 2025 S-3

As filed with the Securities and Exchange Commission on September 2, 2025

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on September 2, 2025 Registration No.

August 25, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 21, 2025 Immuneering Corpo

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 21, 2025 Immuneering Corporation (Exact name of Registrant as Specified in its Charter) Delaware 001-40675 26-1976972 (State or other jurisdiction of incorporation or organizat

August 25, 2025 EX-4.2

COMMON STOCK PURCHASE WARRANT IMMUNEERING CORPoration

Exhibit 4.2 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE UNITED STATES SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFF

August 25, 2025 EX-4.1

PRE-FUNDED COMMON STOCK PURCHASE WARRANT IMMUNEERING CORPoration

Exhibit 4.1 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE UNITED STATES SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFF

August 25, 2025 EX-99.1

Immuneering Announces $25 Million Private Placement

Exhibit 99.1 Immuneering Announces $25 Million Private Placement CAMBRIDGE, Mass., August 21, 2025 – Immuneering Corporation (Nasdaq: IMRX), a clinical-stage oncology company focused on keeping cancer patients alive, today announced that it has entered into a definitive securities purchase agreement for a private placement of securities to top-tier institutional and other accredited investors, tha

August 25, 2025 EX-10.2

REGISTRATION RIGHTS AGREEMENT

Exhibit 10.2 REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (this “Agreement”) is made and entered into as of August 21, 2025, between Immuneering Corporation, Inc., a Delaware corporation (the “Company”), and each of the several purchasers signatory hereto (each such purchaser, a “Purchaser” and, collectively, the “Purchasers”). This Agreement is made pursuant to the Securities

August 25, 2025 EX-10.1

SECURITIES PURCHASE AGREEMENT

Exhibit 10.1 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of August 21, 2025, between Immuneering Corporation, a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively, the “Purchasers”). WHEREAS, subject to the terms and conditio

August 13, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 00

August 13, 2025 S-3

As filed with the Securities and Exchange Commission on August 13, 2025

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on August 13, 2025 Registration No.

August 13, 2025 EX-4.3

Form of Indenture.

Exhibit 4.3 IMMUNEERING CORPORATION INDENTURE Dated as of , 20 [TRUSTEE] Trustee TABLE OF CONTENTS Page ARTICLE I. DEFINITIONS AND INCORPORATION BY REFERENCE 1 Section 1.1. Definitions 1 Section 1.2. Other Definitions 4 Section 1.3. Incorporation by Reference of Trust Indenture Act 4 Section 1.4. Rules of Construction 5 ARTICLE II. THE SECURITIES 5 Section 2.1. Issuable in Series 5 Section 2.2. Es

August 13, 2025 EX-FILING FEES

Filing Fee Table.

Calculation of Filing Fee Tables S-3 Immuneering Corp Table 1: Newly Registered and Carry Forward Securities ☐Not Applicable Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forward Form Type Carry Forward File Number Carry Forward Initial Effective Date Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward Newly Registered Securities Equity Common Stock, $0.

August 13, 2025 EX-1.2

Equity Distribution Agreement, dated as of August 13, 2025, by and between Immuneering Corporation and Piper Sandler & Co.

  Exhibit 1.2   IMMUNEERING CORPORATION   EQUITY DISTRIBUTION AGREEMENT   August 13, 2025   PIPER SANDLER & CO. U.S. Bancorp Center 800 Nicollet Mall Minneapolis, Minnesota 55402   Ladies and Gentlemen:   As further set forth in this agreement (this “Agreement”), Immuneering Corporation, a Delaware corporation (the “Company”), proposes to issue and sell from time to time through Piper Sandler & Co

August 13, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 13, 2025 Immuneering Corpo

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 13, 2025 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission

August 13, 2025 EX-99.1

Immuneering Reports Second Quarter 2025 Financial Results and Provides Business Updates - Company now plans to share updated OS and PFS data from first-line pancreatic cancer patients (N = 34) treated with atebimetinib + mGnP in Q3 2025, earlier than

Exhibit 99.1 Immuneering Reports Second Quarter 2025 Financial Results and Provides Business Updates - Company now plans to share updated OS and PFS data from first-line pancreatic cancer patients (N = 34) treated with atebimetinib + mGnP in Q3 2025, earlier than prior guidance - - Exceptional 94% overall survival (OS) observed at 6 months in ongoing Phase 2a trial of atebimetinib plus modified Ge

June 23, 2025 424B5

Up to $31,293,843.89 IMMUNEERING CORPORATION Class A Common Stock

As Filed Pursuant to Rule 424(b)(5) Registration No. 333-266738 PROSPECTUS SUPPLEMENT (To Prospectus and Prospectus Supplement dated August 19, 2022 and Prospectus Supplement dated March 20, 2025) Up to $31,293,843.89 IMMUNEERING CORPORATION Class A Common Stock This prospectus supplement (this “Current Prospectus Supplement”) supplements the prospectus dated August 19, 2022 (the “Base Prospectus”

June 17, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 17, 2025 Immuneering Corpora

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 17, 2025 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission F

June 16, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 13, 2025 Immuneering Corpora

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 13, 2025 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission F

May 5, 2025 S-8

As filed with the Securities and Exchange Commission on May 5, 2025

As filed with the Securities and Exchange Commission on May 5, 2025 Registration No.

May 5, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0

May 5, 2025 EX-FILING FEES

Filing Fee Table.

Exhibit 107.1 Calculation of Filing Fee Tables Form S-8 (Form Type) Immuneering Corporation (Exact Name of Registrant as Specified in its Charter) Table 1—Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount to be Registered (1) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Class A common s

May 5, 2025 EX-99.1

Immuneering Reports First Quarter 2025 Financial Results and Provides Business Updates - Progression-free survival data from more than 30 patients with first line pancreatic cancer in the ongoing Phase 2a trial of IMM-1-104 trial planned for announce

Exhibit 99.1 Immuneering Reports First Quarter 2025 Financial Results and Provides Business Updates - Progression-free survival data from more than 30 patients with first line pancreatic cancer in the ongoing Phase 2a trial of IMM-1-104 trial planned for announcement in 2Q’25 - - Reported positive data from the Company’s ongoing Phase 2a trial of lead program IMM-1-104, including encouraging respo

May 5, 2025 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 5, 2025 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission Fil

April 21, 2025 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.    )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.    ) Filed by the Registrant x Filed by a party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule

April 21, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.    )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.    ) Filed by the Registrant x Filed by a party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o De

March 20, 2025 EX-99.1

Immuneering Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Business Updates - Reported positive data updates from its ongoing Phase 2a trial of lead program IMM-1-104, including encouraging responses in combination with chem

Exhibit 99.1 Immuneering Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Business Updates - Reported positive data updates from its ongoing Phase 2a trial of lead program IMM-1-104, including encouraging responses in combination with chemotherapy in first-line pancreatic cancer - - Announced a clinical trial supply agreement with Regeneron Pharmaceuticals to evaluate IMM-1

March 20, 2025 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2025 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission

March 20, 2025 EX-10.14

Immuneering Corporation 2025 Employment Inducement Award Plan and forms of award agreements thereunder

IMMUNEERING CORPORATION 2025 EMPLOYMENT INDUCEMENT AWARD PLAN ARTICLE I. PURPOSE The Plan’s purpose is to enhance the Company’s ability to attract, retain and motivate persons who make (or are expected to make) important contributions to the Company by providing these individuals with equity ownership opportunities and/or equity-linked compensatory opportunities. Capitalized terms used in the Plan

March 20, 2025 EX-19.1

Immuneering Corporation Insider Trading Compliance Policy and Procedures

IMMUNEERING CORPORATION INSIDER TRADING COMPLIANCE POLICY AND PROCEDURES Federal and state laws prohibit trading in the securities of a company while in possession of material nonpublic information and in breach of a duty of trust or confidence.

March 20, 2025 424B5

IMMUNEERING CORPORATION Up to $21,503,435.70 of Class A Common Stock

As Filed Pursuant to Rule 424(b)(5) Registration No. 333-266738 PROSPECTUS SUPPLEMENT (To Prospectus and Prospectus Supplement dated August 19, 2022) IMMUNEERING CORPORATION Up to $21,503,435.70 of Class A Common Stock This prospectus supplement (the “Prospectus Supplement”) supplements the prospectus dated August 19, 2022 and the prospectus supplement dated August 19, 2022 (together, the “ATM Pro

March 20, 2025 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-40

January 13, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 13, 2025 Immuneering Corp

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 13, 2025 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commissio

January 7, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 7, 2025 Immuneering Corpo

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 7, 2025 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission

November 14, 2024 SC 13G/A

IMRX / Immuneering Corporation / Cormorant Asset Management, LP Passive Investment

SC 13G/A 1 cormorant-imrx093024a4.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 4)* Immuneering Corporation (Name of Issuer) Class A Common Stock (Title of Class of Securities) 45254E107 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of this Statement) Check the appropriate b

November 14, 2024 SC 13G/A

IMRX / Immuneering Corporation / CITADEL ADVISORS LLC - SC 13G/A Passive Investment

SC 13G/A 1 tm2427061d11sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G* (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2 (Amendment No. 4)* Immuneering Corp (Name of Issuer) Class A common Stock, par value $0.001 per share (the “Shares”

November 13, 2024 EX-99.1

Immuneering Reports Third Quarter 2024 Financial Results and Provides Business Updates - Announced Positive Initial Data, Including Complete and Partial Responses, with IMM-1-104 in Combination with Chemotherapy in First-Line Pancreatic Cancer Patien

Exhibit 99.1 Immuneering Reports Third Quarter 2024 Financial Results and Provides Business Updates - Announced Positive Initial Data, Including Complete and Partial Responses, with IMM-1-104 in Combination with Chemotherapy in First-Line Pancreatic Cancer Patients - - Granted FDA Orphan Drug Designation for IMM-1-104 in the Treatment of Pancreatic Cancer and Fast Track Designation in First-line P

November 13, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 13, 2024 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commissi

November 13, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numbe

October 2, 2024 8-K/A

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K/A CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 11, 2024 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commissio

September 12, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 12, 2024 Immuneering Co

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 12, 2024 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commiss

August 6, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 6, 2024 Immuneering Corpor

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 6, 2024 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission

August 6, 2024 EX-10.1

Immuneering Corporation Non-Employee Director Compensation Program, as amended

Immuneering Corporation Non-Employee Director Compensation Program (AS AMENDED MAY 21, 2024) Non-employee members of the board of directors (the “Board”) of Immuneering Corporation (the “Company”) shall receive cash and equity compensation as set forth in this Non-Employee Director Compensation Program (this “Program”).

August 6, 2024 EX-99.1

Immuneering Reports Second Quarter 2024 Financial Results and Provides Business Updates - Enrollment progressing well across all arms in the IMM-1-104 Phase 2a Trial, with Initial Data from Multiple Arms Expected in 2H 2024 - - Granted FDA Fast Track

Exhibit 99.1 Immuneering Reports Second Quarter 2024 Financial Results and Provides Business Updates - Enrollment progressing well across all arms in the IMM-1-104 Phase 2a Trial, with Initial Data from Multiple Arms Expected in 2H 2024 - - Granted FDA Fast Track Designation for IMM-1-104 in First-line Pancreatic Cancer - - Preclinical Data Presented at AACR Demonstrates that Combining IMM-1-104 w

August 6, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 00

June 13, 2024 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 12, 2024 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission F

May 23, 2024 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 21, 2024 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission Fi

May 7, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 7, 2024 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 7, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0

May 7, 2024 EX-99.1

Immuneering Reports First Quarter 2024 Financial Results and Provides Business Updates - Reported Positive Topline Results from Phase 1 Portion of its Phase 1/2a Clinical Trial of IMM-1-104 in RAS-Mutant Solid Tumors - - First Patient Dosed in Phase

Exhibit 99.1 Immuneering Reports First Quarter 2024 Financial Results and Provides Business Updates - Reported Positive Topline Results from Phase 1 Portion of its Phase 1/2a Clinical Trial of IMM-1-104 in RAS-Mutant Solid Tumors - - First Patient Dosed in Phase 2a Portion of Phase 1/2a Clinical Trial of IMM-1-104; Initial Data from Multiple IMM-1-104 Phase 2a Arms Expected in 2024 - - Presented P

April 23, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.    )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.    ) Filed by the Registrant x Filed by a party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o De

April 23, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.    )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.    ) Filed by the Registrant x Filed by a party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule

April 15, 2024 SC 13G/A

IMRX / Immuneering Corporation / Cormorant Asset Management, LP - AMENDMENT NO. 3 Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* Immuneering Corporation (Name of Issuer) Class A Common Stock (Title of Class of Securities) 45254E107 (CUSIP Number) April 3, 2024 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which

March 27, 2024 SC 13G/A

IMRX / Immuneering Corporation / Merrin Investors LLC - SC 13G/A Passive Investment

Merrin Investors LLC UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

March 14, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 11, 2024 Immuneering Corpor

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 11, 2024 Immuneering Corporation (Exact name of Registrant as Specified in its Charter) Delaware 001-40675 26-1976972 (State or other jurisdiction of incorporation or organizati

March 1, 2024 EX-10.15

Immuneering Corporation Non-Employee Director Compensation Program, as amended, effective January 1, 2024

Immuneering Corporation Non-Employee Director Compensation Program (EFFECTIVE AS OF JANUARY 1, 2024) Non-employee members of the board of directors (the “Board”) of Immuneering Corporation (the “Company”) shall receive cash and equity compensation as set forth in this Non-Employee Director Compensation Program (this “Program”).

March 1, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 1, 2024 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission F

March 1, 2024 EX-10.6

Letter Agreement, dated June 14, 2023, by and between Mallory Morales and Immuneering

Mallory Morales June 14, 2023 Dear Mallory: We are pleased to inform you about an important change to your compensation in connection with your promotion from Vice President, Finance to Chief Accounting Officer! You are being awarded an annual salary increase from $325,503.

March 1, 2024 EX-10.8

Employment Agreement, dated March 24, 2023, by and between Harold E. Brakewood and Immuneering Corporation

Employment Agreement This Employment Agreement (this “Agreement”), dated as of March 24, 2023, is made by and between Immuneering Corporation, a Delaware corporation (together with any successor thereto, the “Company”), and Harold E.

March 1, 2024 EX-10.4

Employment Agreement, dated July 23, 2021, by and between Mallory Morales and Immuneering Corporation

Employment Agreement This Employment Agreement (this “Agreement”), dated as of July 23, 2021, is made by and between Immuneering Corporation, a Delaware corporation (together with any successor thereto, the “Company”), and Mallory Morales (“Executive”) (collectively referred to herein as the “Parties” or individually referred to as a “Party”), and will become effective, if at all, upon the date of the Company’s initial public offering of common stock (“IPO”) pursuant to an effective registration statement filed under the Securities Act of 1933, as amended (the “Effective Date”).

March 1, 2024 EX-97.1

Immuneering Corporation Policy for Recovery of Erroneously Awarded Compensation

IMMUNEERING CORPORATION POLICY FOR RECOVERY OF ERRONEOUSLY AWARDED COMPENSATION Immuneering Corporation (the “Company”) has adopted this Policy for Recovery of Erroneously Awarded Compensation (the “Policy”), effective as of October 2, 2023 (the “Effective Date”).

March 1, 2024 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-40

March 1, 2024 EX-99.1

Immuneering Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Business Updates - Topline data from the Phase 1 portion of Phase 1/2a trial of IMM-1-104 expected in March 2024 - - Dosing of first patient in the expanded Phase 2a

Exhibit 99.1 Immuneering Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Business Updates - Topline data from the Phase 1 portion of Phase 1/2a trial of IMM-1-104 expected in March 2024 - - Dosing of first patient in the expanded Phase 2a portion of Phase 1/2a trial of IMM-1-104 expected in March 2024; initial data from multiple arms expected in 2024 - - FDA Fast Track des

February 14, 2024 SC 13G/A

IMRX / Immuneering Corporation / CITADEL ADVISORS LLC - SC 13G/A Passive Investment

SC 13G/A 1 tm243573d8sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G* (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2 (Amendment No. 3)* Immuneering Corp (Name of Issuer) Class A common stock, par value $0.001 per share (the “Shares”)

February 2, 2024 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 1, 2024 Immuneering Corporation (Exact name of registrant as specified in its charter) Delaware 001-40675 26-1976972 (State or other jurisdiction of incorporation or organiza

February 2, 2024 EX-3.1

Amended and Restated Bylaws of Immuneering Corporation

Exhibit 3.1 AMENDED AND RESTATED BYLAWS OF IMMUNEERING CORPORATION (a Delaware corporation) as of February 1, 2024 TABLE OF CONTENTS Page ARTICLE I - CORPORATE OFFICES 1 1.1 REGISTERED OFFICE 1 1.2 OTHER OFFICES 1 ARTICLE II - MEETINGS OF STOCKHOLDERS 1 2.1 PLACE OF MEETINGS 1 2.2 ANNUAL MEETING 1 2.3 SPECIAL MEETING 1 2.4 ADVANCE NOTICE PROCEDURES FOR BUSINESS BROUGHT BEFORE A MEETING 2 2.5 NOTIC

January 16, 2024 SC 13G/A

IMRX / Immuneering Corporation / Zeskind Benjamin J. - SC 13G/A Passive Investment

SC 13G/A 1 zeskind-2024schedule13game.htm SC 13G/A Securities and Exchange Commission Washington, D.C. 20549 Schedule 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.13d-1(b), (c) and (d) and Amendments Thereto Filed Pursuant to § 240.13d-2 UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 2)* Immuneering Corporation (Name of Issuer) Class A Common Stock

November 9, 2023 EX-10.2

Separation Agreement and Release, by and between Scott Barrett and Immuneering Corporation, dated November 8, 2023

Separation Agreement and Release This Separation Agreement and Release (“Agreement”) is made by and between Scott Barrett, M.

November 9, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 9, 2023 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commissio

November 9, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numbe

November 9, 2023 EX-10.1

Immuneering Corporation Non-Employee Director Compensation Program, as amended, effective

Immuneering Corporation Non-Employee Director Compensation Program (Effective as of October 16, 2023) Non-employee members of the board of directors (the “Board”) of Immuneering Corporation (the “Company”) shall receive cash and equity compensation as set forth in this Non-Employee Director Compensation Program (this “Program”).

November 9, 2023 EX-99.1

Immuneering Reports Third Quarter 2023 Financial Results and Provides Business Updates -Dose evaluation portion of IMM-1-104 Phase 1/2a trial approximately two-thirds enrolled; Immuneering’s recommendation for a Phase 2 dose expected in early 2024 -

Exhibit 99.1 Immuneering Reports Third Quarter 2023 Financial Results and Provides Business Updates -Dose evaluation portion of IMM-1-104 Phase 1/2a trial approximately two-thirds enrolled; Immuneering’s recommendation for a Phase 2 dose expected in early 2024 - - Expanded clinical development plan for IMM-1-104, Phase 2a portion of study now includes 5 arms (3 monotherapy, 2 combination) and addi

August 3, 2023 EX-10.1

Immuneering Corporation Non-Employee Director Compensation Program, as amended, effective

Immuneering Corporation Non-Employee Director Compensation Program Non-employee members of the board of directors (the “Board”) of Immuneering Corporation (the “Company”) shall receive cash and equity compensation as set forth in this Non-Employee Director Compensation Program (this “Program”).

August 3, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 3, 2023 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission

August 3, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 00

August 3, 2023 EX-99.1

Immuneering Reports Second Quarter 2023 Financial Results and Provides Business Updates - Positive initial pharmacokinetic, pharmacodynamic and safety data presented at American Association for Cancer Research (AACR) annual meeting, with IMM-1-104 de

Exhibit 99.1 Immuneering Reports Second Quarter 2023 Financial Results and Provides Business Updates - Positive initial pharmacokinetic, pharmacodynamic and safety data presented at American Association for Cancer Research (AACR) annual meeting, with IMM-1-104 demonstrating Cmax, half-life, and pERK/pMEK suppression consistent with deep cyclic inhibition of the MAPK pathway - - Completed IMM-1-104

June 15, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 14, 2023 Immuneering Corpora

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 14, 2023 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission F

June 14, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 13, 2023 Immuneering Corpora

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 13, 2023 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission F

May 4, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0

May 4, 2023 EX-99.1

Immuneering Reports First Quarter 2023 Financial Results and Provides Business Updates - Positive Initial Phase 1 Pharmacokinetic, Pharmacodynamic and Safety Data for IMM-1-104 Universal-RAS Program presented at American Association for Cancer Resear

Exhibit 99.1 Immuneering Reports First Quarter 2023 Financial Results and Provides Business Updates - Positive Initial Phase 1 Pharmacokinetic, Pharmacodynamic and Safety Data for IMM-1-104 Universal-RAS Program presented at American Association for Cancer Research (AACR) annual meeting - -First demonstration of novel deep cyclic inhibition mechanism in humans, with IMM-1-104 achieving significant

May 4, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 4, 2023 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 1, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.    )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.    ) Filed by the Registrant x Filed by a party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule

May 1, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.    )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.    ) Filed by the Registrant x Filed by a party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o De

April 24, 2023 SC 13G/A

IMRX / Immuneering Corp Class A / Cormorant Asset Management, LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Immuneering Corporation (Name of Issuer) Class A Common Stock (Title of Class of Securities) 45254E107 (CUSIP Number) April 20, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which

April 19, 2023 424B5

2,727,273 Shares IMMUNEERING CORPORATION CLASS A COMMON STOCK

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(5)  Registration No. 333-266738 PROSPECTUS SUPPLEMENT (To Prospectus dated August 19, 2022) 2,727,273 Shares IMMUNEERING CORPORATION CLASS A COMMON STOCK We are offering 2,727,273 shares of our Class A common stock. Our Class A common stock is listed on The Nasdaq Global Market under the symbol “IMRX.” On April 18, 2023, the last reported sale price

April 19, 2023 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 18, 2023 Immuneering Corporation (Exact name of Registrant as Specified in its Charter) Delaware 001-40675 26-1976972 (State or other jurisdiction of incorporation or organizati

April 19, 2023 EX-1.1

Underwriting Agreement, dated as of April 18, 2023, by and among Immuneering Corporation, Jefferies LLC, Cowen and Company, LLC and Guggenheim Securities, LLC

Exhibit 1.1 Execution Copy 2,727,273 Shares IMMUNEERING CORPORATION CLASS A COMMON STOCK (PAR VALUE $0.001 PER SHARE) UNDERWRITING AGREEMENT April 18, 2023 April 18, 2023 Jefferies LLC Cowen and Company, LLC Guggenheim Securities, LLC As Representatives of the several Underwriters named in Schedule I hereto c/o Jefferies LLC 520 Madison Avenue, 10th Floor New York, New York 10022 c/o Cowen and Com

April 18, 2023 EX-99.1

Building a Universal - RAS Franchise Nasdaq: IMRX APRIL 2023 Investor Presentation

Exhibit 99.1 Building a Universal - RAS Franchise Nasdaq: IMRX APRIL 2023 Investor Presentation   2023 Corporate Presentation 2 This presentation contains forward - looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 . All statements contained in this presentation that do not relate to matters of historical fact should be considered forward - looking state

April 18, 2023 EX-99.2

Immuneering Announces Positive Initial Phase 1 Pharmacokinetic, Pharmacodynamic and Safety Data for IMM-1-104 Universal-RAS Program; Accelerates Study Timeline

Exhibit 99.2 Immuneering Announces Positive Initial Phase 1 Pharmacokinetic, Pharmacodynamic and Safety Data for IMM-1-104 Universal-RAS Program; Accelerates Study Timeline ● Data presented at AACR Annual Meeting support IMM-1-104's potential to address a broad population of patients with RAS mutant tumors ● IMM-1-104 well tolerated with no dose limiting toxicities (DLTs) or serious adverse events

April 18, 2023 424B5

IMMUNEERING CORPORATION CLASS A COMMON STOCK

TABLE OF CONTENTS The information in this preliminary prospectus supplement and the accompanying prospectus, relating to an effective registration statement under the Securities Act of 1933, as amended, is not complete and may be changed.

April 18, 2023 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 18, 2023 Immuneering Corporation (Exact name of Registrant as Specified in its Charter) Delaware 001-40675 26-1976972 (State or other jurisdiction of incorporation or organizati

March 6, 2023 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 or ☐TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-4067

March 6, 2023 EX-99.2

2 2023 Corporate Presentation This presentation contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this presentation that do not relate to matters of historical

Exhibit 99.2 Building a Universal-RAS Franchise Nasdaq: IMRX With the potential to benefit more than 1.5 million cancer MARCH 2023 patients 2 2023 Corporate Presentation This presentation contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this presentation that do not relate to matters of historical fact shoul

March 6, 2023 EX-99.1

Immuneering Reports Fourth Quarter and Full Year 2022 Financial Results and Provides Business Updates First patient dosed in Phase 1/2a clinical trial of IMM-1-104 in advanced solid tumors with any RAS mutation Provides debut guidance for IMM-1-104 p

Exhibit 99.1 Immuneering Reports Fourth Quarter and Full Year 2022 Financial Results and Provides Business Updates First patient dosed in Phase 1/2a clinical trial of IMM-1-104 in advanced solid tumors with any RAS mutation Provides debut guidance for IMM-1-104 program: initial Phase 1 PK and safety data expected in mid-2023, initial Phase 1 PD modeling and additional PK and safety data expected i

March 6, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 6, 2023 Immuneering Corpora

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 6, 2023 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission F

February 14, 2023 SC 13G/A

IMRX / Immuneering Corporation Class A / CITADEL ADVISORS LLC - SC 13G/A Passive Investment

SC 13G/A 1 tm233474-13sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G* (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2 (Amendment No. 2)* Immuneering Corp (Name of Issuer) Class A Common Stock, par value $0.001 per share (the “Shares”)

February 14, 2023 SC 13G/A

IMRX / Immuneering Corporation Class A / Cormorant Asset Management, LP Passive Investment

SC 13G/A 1 schedule13g.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Immuneering Corporation (Name of Issuer) Class A Common Stock (Title of Class of Securities) 45254E107 (CUSIP Number) December 31, 2022 (Date of Event which Requires Filing of this Statement) Check the appropriate box to design

February 8, 2023 SC 13G/A

IMRX / Immuneering Corporation Class A / Zeskind Benjamin J. - SC 13G/A Passive Investment

SC 13G/A 1 tm235619d1sc13ga.htm SC 13G/A Securities and Exchange Commission Washington, D.C. 20549 Schedule 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.13d-1(b), (c) and (d) and Amendments Thereto Filed Pursuant to § 240.13d-2 UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 1)* Immuneering Corporation (Name of Issuer) Class A Common Stock (Title of

November 10, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents ? 2 ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

November 10, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT ? Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 ? Date of Report (Date of earliest event reported): November 10, 2022 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) ? ? ? ? Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorpor

November 10, 2022 EX-99.1

Immuneering Reports Third Quarter 2022 Financial Results and Recent Business Highlights Recruiting has Commenced for Phase 1/2a Clinical Trial of IMM-1-104 in Advanced Solid Tumors with RAS Mutations (NCT05585320), with the First Patient Expected to

Exhibit 99.1 Immuneering Reports Third Quarter 2022 Financial Results and Recent Business Highlights ? Recruiting has Commenced for Phase 1/2a Clinical Trial of IMM-1-104 in Advanced Solid Tumors with RAS Mutations (NCT05585320), with the First Patient Expected to be Dosed this Quarter ? Shares Promising Preclinical Data on Second Program IMM-6-415 at the 37th Annual Meeting of SITC, Demonstrating

September 19, 2022 8-K/A

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 14, 2022 Immuneering Corporation (Exact name of registrant as specified in its charter) Delaware 001-40675 26-1976972 (State or other jurisdiction of incorporation or organi

August 17, 2022 CORRESP

August 17, 2022

August 17, 2022 Via EDGAR Transmission United States Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.

August 10, 2022 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Immuneering Corporation (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Newly Registered Securities Fees to be Paid Equity Class A common stock, $0.

August 10, 2022 10-Q

2 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents 2 ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

August 10, 2022 EX-99.1

Immuneering Reports Second Quarter 2022 Financial Results and Recent Business Highlights IND filing for IMM-1-104, which has displayed broad preclinical pan-KRAS/NRAS activity, expected this quarter; Enrollment of first patient in planned Phase 1/2a

Exhibit 99.1 Immuneering Reports Second Quarter 2022 Financial Results and Recent Business Highlights IND filing for IMM-1-104, which has displayed broad preclinical pan-KRAS/NRAS activity, expected this quarter; Enrollment of first patient in planned Phase 1/2a clinical trial expected in Q4 2022 IND filing for IMM-6-415, designed to sensitize resistant tumors to select immunotherapies, expected i

August 10, 2022 EX-4.3

Form of Indenture.

Exhibit 4.3 IMMUNEERING CORPORATION INDENTURE Dated as of , 20 [TRUSTEE] Trustee TABLE OF CONTENTS Page ARTICLE I. DEFINITIONS AND INCORPORATION BY REFERENCE 1 Section 1.1. Definitions. 1 Section 1.2. Other Definitions. 4 Section 1.3. Incorporation by Reference of Trust Indenture Act. 4 Section 1.4. Rules of Construction. 5 ARTICLE II. THE SECURITIES 5 Section 2.1. Issuable in Series. 5 Section 2.

August 10, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT ? Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 ? Date of Report (Date of earliest event reported): August 10, 2022 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) ? ? ? ? Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporat

August 10, 2022 S-3

As filed with the Securities and Exchange Commission on August 10, 2022

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on August 10, 2022 Registration No.

August 10, 2022 EX-1.2

Equity Distribution Agreement, dated as of August 10, 2022, by and between Immuneering Corporation and Piper Sandler & Co.

Exhibit 1.2 IMMUNEERING CORPORATION EQUITY DISTRIBUTION AGREEMENT August 10, 2022 PIPER SANDLER & CO. U.S. Bancorp Center 800 Nicollet Mall Minneapolis, Minnesota 55402 Ladies and Gentlemen: As further set forth in this agreement (this ?Agreement?), Immuneering Corporation, a Delaware corporation (the ?Company?), proposes to issue and sell from time to time through Piper Sandler & Co. (the ?Agent?

July 25, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): July 20, 2022 Immuneering Corporation (Exact name of registrant as specified in its charter) Delaware 001-40675 26-1976972 (State or other jurisdiction of incorporation or organizatio

July 25, 2022 EX-10.1

Letter Agreement, by and between Immuneering Corporation and Mallory Morales, dated as of July 25, 2022

Exhibit 10.1 VIA EMAIL July 25, 2022 Dear Mallory, As we discussed, this letter agreement (the ?Letter Agreement?), effective as of August 10, 2022, describes compensation payable to you by Immuneering Corporation (the ?Company?) under the terms set forth below. 1. Cash Bonus Payments. You are eligible to receive (i) a payment of $15,000 in cash payable on August 15, 2022, and (ii) a payment of $1

June 24, 2022 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 21, 2022 Immuneering Corporation (Exact name of registrant as specified in its charter) Delaware 001-40675 26-1976972 (State or other jurisdiction of incorporation or organizatio

May 10, 2022 10-Q

2 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents 2 ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

May 10, 2022 EX-99.1

Immuneering Reports First Quarter 2022 Financial Results and Recent Business Highlights IND filing for IMM-1-104 expected in Q3 2022; Enrollment of the first patient expected in Q4 2022 IND filing for IMM-6-415, designed to sensitize resistant tumors

Exhibit 99.1 Immuneering Reports First Quarter 2022 Financial Results and Recent Business Highlights IND filing for IMM-1-104 expected in Q3 2022; Enrollment of the first patient expected in Q4 2022 IND filing for IMM-6-415, designed to sensitize resistant tumors to select immunotherapies, expected in 2023 Cash, cash equivalents and marketable securities of $137.8M is expected to provide cash runw

May 10, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 10, 2022 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission Fi

May 2, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Ame

DEFA14A 1 tm2213547d2defa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a party other than the Registrant ¨ Check the appropriate box

May 2, 2022 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Ame

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 ? SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.????) ? Filed by the Registrant ? Filed by a party other than the Registrant ? ? Check the appropriate box: ? Preliminar

March 10, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 10, 2022 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorporation) (Commission

March 10, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

March 10, 2022 EX-99.1

Immuneering Reports Fourth Quarter and Full Year 2021 Financial Results and Provides Business Updates Lead Product Candidate, IMM-1-104, displays broad activity against a wide range of animal tumor models driven by MAPK pathway activating mutations i

Exhibit 99.1 Immuneering Reports Fourth Quarter and Full Year 2021 Financial Results and Provides Business Updates ? Lead Product Candidate, IMM-1-104, displays broad activity against a wide range of animal tumor models driven by MAPK pathway activating mutations including KRAS-G12D, KRAS-G12S, KRAS-G12C, NRAS-Q61R, and BRAF-V600E; IND filing is expected in Q3 2022 ? IMM-6-415, designed to sensiti

March 10, 2022 EX-4.3

Description of Securities

Exhibit 4.3 DESCRIPTION OF THE REGISTRANT?S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED Immuneering Corporation had one class of securities registered under Section 12 of the Securities Exchange Act of 1934, as amended (the ?Exchange Act?). References herein to ?we,? ?us,? ?our? and the ?Company? refer to Immuneering Corporation and not to any of

March 10, 2022 EX-21.1

Subsidiaries of Immuneering Corporation

Exhibit 21.1 Subsidiaries of Immuneering Corporation Immuneering Securities Corporation BioArkive, Inc.

February 14, 2022 SC 13G/A

IMRX / Immuneering Corporation Class A / CITADEL ADVISORS LLC - IMMUNEERING CORP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G* (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO ? 240.13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO ? 240.13d-2 (Amendment No. 1)* Immuneering Corp (Name of Issuer) Class A common stock, par value $0.001 per share (the ?Shares?) (Title of Class of Securities) 45254E107

February 10, 2022 SC 13G

IMRX / Immuneering Corporation Class A / Zeskind Benjamin J. - SC 13G Passive Investment

Securities and Exchange Commission Washington, D.C. 20549 Schedule 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to ? 240.13d-1(b), (c) and (d) and Amendments Thereto Filed Pursuant to ? 240.13d-2 UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. )* Immuneering Corporation (Name of Issuer) Class A Common Stock (Title of Class of Securities) 45254E107 (CUSIP Numb

January 18, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 14, 2022 Immuneering Corporation (Exact name of registrant as specified in its charter) Delaware 001-40675 26-1976972 (State or other jurisdiction of incorporation or organiza

January 18, 2022 EX-99.1

Immuneering Strengthens Board of Directors with the Appointment of Diana F. Hausman, M.D. Industry Executive Brings More than 20 Years of Clinical Drug Development Expertise

Exhibit 99.1 Immuneering Strengthens Board of Directors with the Appointment of Diana F. Hausman, M.D. Industry Executive Brings More than 20 Years of Clinical Drug Development Expertise CAMBRIDGE, Mass., January 18, 2022?Immuneering Corporation (Nasdaq: IMRX), a biopharmaceutical company advancing a robust pipeline of oncology and neuroscience product candidates that are designed to uniquely disr

December 22, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 22, 2021 Immuneering Corporation (Exact name of registrant as specified in its charter) Delaware 001-40675 26-1976972 (State or other jurisdiction of incorporation or organiz

December 22, 2021 EX-10.1

Lease Agreement, by and between BioArkive, Inc. and Thornmint 13, LLC, dated as of July 22, 2021

Exhibit 10.1 INITIALS INITIALS ? 2019 AIR CRE. All Rights Reserved. Last Edited: 7/22/2021 12:33 PM STN?27.30, Revised 10?22?2020 Page 1 of 16 STANDARD INDUSTRIAL/COMMERCIAL SINGLE?TENANT LEASE ? NET (DO NOT USE THIS FORM FOR MULTI?TENANT BUILDINGS) 1. Basic Provisions ("Basic Provisions"). 1.1 Pares. This Lease ("Lease"), dated for reference purposes only July 22, 2021 , is made by and between Th

December 22, 2021 EX-2.1

Share Purchase Agreement by and among Immuneering Corporation, BioArkive, Inc. and BioArkive’s shareholders, dated as of December 22, 2021

EX-2.1 2 tm2136034d1ex2-1.htm EXHIBIT 2.1 Exhibit 2.1 SHARE PURCHASE AGREEMENT by and among BioArkive, Inc., the Sellers Listed on the Signature Pages Hereto, and the Purchaser DATED AS OF DECEMBER 22, 2021 [NO AGREEMENT, ORAL OR WRITTEN, REGARDING OR RELATING TO ANY OF THE MATTERS COVERED BY THIS DOCUMENT HAS BEEN ENTERED INTO BETWEEN THE PARTIES. IT IS NOT INTENDED TO CREATE, AND WILL NOT BE DEE

November 9, 2021 EX-99.1

Immuneering Reports Third Quarter 2021 Financial Results and Recent Business Highlights Successfully completed upsized initial public offering raising $129.4 million in gross proceeds, providing runway into 2024 Company expects to file IND for IMM-1-

Exhibit 99.1 Immuneering Reports Third Quarter 2021 Financial Results and Recent Business Highlights ? Successfully completed upsized initial public offering raising $129.4 million in gross proceeds, providing runway into 2024 ? Company expects to file IND for IMM-1-104 in Q1 2022 ? CAMBRIDGE, Mass., November 9, 2021? Immuneering Corporation (Nasdaq: IMRX), a biopharmaceutical company advancing a

November 9, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

November 9, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT ? Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 ? Date of Report (Date of earliest event reported): November 9, 2021 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) ? ? ? ? Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorpora

September 9, 2021 EX-3.2

Amended and Restated Bylaws of Immuneering Corporation

Exhibit 3.2 AMENDED AND RESTATED BYLAWS OF IMMUNEERING CORPORATION (a Delaware corporation) ? ? ? ? TABLE OF CONTENTS Page ? ARTICLE I - CORPORATE OFFICES?1 1.1REGISTERED OFFICE?1 1.2OTHER OFFICES?1 ARTICLE II - MEETINGS OF STOCKHOLDERS?1 2.1PLACE OF MEETINGS?1 2.2ANNUAL MEETING?1 2.3SPECIAL MEETING?1 2.4ADVANCE NOTICE PROCEDURES FOR BUSINESS BROUGHT BEFORE A MEETING?2 2.5ADVANCE NOTICE PROCEDURES

September 9, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT ? Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 ? Date of Report (Date of earliest event reported): September 9, 2021 Immuneering Corporation (Exact name of Registrant as Specified in Its Charter) ? ? ? ? Delaware 001-40675 26-1976972 (State or Other Jurisdiction of Incorpor

September 9, 2021 EX-99.1

Immuneering Reports Second Quarter 2021 Financial Results and Provides Business Updates Recently completed upsized initial public offering raising $129.4 million in gross proceeds, providing runway into 2024 Company expects to file IND for IMM-1-104

Exhibit 99.1 Immuneering Reports Second Quarter 2021 Financial Results and Provides Business Updates ? Recently completed upsized initial public offering raising $129.4 million in gross proceeds, providing runway into 2024 ? Company expects to file IND for IMM-1-104 in Q1 2022 ? CAMBRIDGE, Mass., September 9, 2021? Immuneering Corporation (Nasdaq: IMRX), a biopharmaceutical company advancing a rob

September 9, 2021 EX-3.1

Amended and Restated Certificate of Incorporation of Immuneering Corporation

Exhibit 3.1 ? AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF IMMUNEERING CORPORATION ? Immuneering Corporation (the ?Corporation?), a corporation organized and existing under the General Corporation Law of the State of Delaware (the ?DGCL?), does hereby certify as follows: 1.The name of the Corporation is Immuneering Corporation. The Corporation was incorporated under the name Immuneering Co

September 9, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

August 13, 2021 SC 13G

IMRX / Immuneering Corporation Class A / CITADEL ADVISORS LLC - IMMUNEERING CORPORATION Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G* (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO ? 240.13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO ? 240.13d-2 (Amendment No. )* Immuneering Corporation (Name of Issuer) Class A common stock, par value $0.001 per share (Title of Class of Securities) 45254E107 (CUSIP Nu

August 13, 2021 EX-99.1

JOINT FILING AGREEMENT

EXHIBIT 99.1 JOINT FILING AGREEMENT The undersigned hereby agree that the Statement on Schedule 13G filed herewith (and any amendments thereto), relating to the Class A common stock of Immuneering Corporation, a Delaware corporation, is being filed jointly with the Securities and Exchange Commission pursuant to Rule 13d-1(c) under the Securities Exchange Act of 1934, as amended, on behalf of each

August 13, 2021 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 2 exhibit99-1.htm JOINT FILING AGREEMENT BY AND AMONG THE REPORTING PERSONS Exhibit 99.1 JOINT FILING AGREEMENT This Joint Filing Agreement, dated as of August 13, 2021, is by and among Cormorant Global Healthcare Master Fund, LP, Cormorant Global Healthcare GP, LLC, Cormorant Private Healthcare Fund III, LP, Cormorant Private Healthcare GP III, LLC, Cormorant Asset Management, LP and Bihu

August 13, 2021 SC 13G

IMRX / Immuneering Corporation Class A / Cormorant Asset Management, LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Immuneering Corporation (Name of Issuer) Class A Common Stock (Title of Class of Securities) 45254E107 (CUSIP Number) August 3, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which

August 11, 2021 SC 13G

IMRX / Immuneering Corporation Class A / Merrin Investors LLC - SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Immuneering Corp. (Name of Issuer) Class A Common Stock (Title of Class of Securities) 45254E107 (CUSIP Number) July 31, 2021 (Date of Event which Requires Filing of this amended Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is

August 10, 2021 SC 13G

IMRX / Immuneering Corporation Class A / PRICE T ROWE ASSOCIATES INC /MD/ - IMRX AS OF 07/31/2021 Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. ) Immuneering Corp (Name of Issuer) COMMON STOCK (Title of Class of Securities) 45254E107 (CUSIP NUMBER) July 31, 2021 (Date of Event which Requires Filing of Statement) Check the appropriate box to designate the Rule pursuant to which this Schedule is filed

August 3, 2021 S-8

As filed with the Securities and Exchange Commission on August 3, 2021

As filed with the Securities and Exchange Commission on August 3, 2021 Registration No.

July 30, 2021 424B4

7,500,000 Shares Immuneering Corporation Class A Common Stock

TABLE OF CONTENTS ? Filed Pursuant to Rule 424(b)(4)? ?Registration No. 333-257791? 7,500,000 Shares Immuneering Corporation Class A Common Stock ? We are offering 7,500,000 shares of our Class A common stock. This is our initial public offering and prior to this offering, no public market existed for our Class A common stock. The initial public offering price is $15.00 per share. Our Class A comm

July 29, 2021 S-1MEF

As filed with the Securities and Exchange Commission on July 29, 2021. Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT THE SECURITIES ACT OF 1933 IMMUNEERING CORPORATION (E

As filed with the Securities and Exchange Commission on July 29, 2021. Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 IMMUNEERING CORPORATION (Exact name of registrant as specified in its charter) Delaware 2834 26-1976972 (State or other jurisdiction of incorporation or organization) (Pr

July 28, 2021 CORRESP

July 28, 2021

1271 Avenue of the Americas New York, New York 10020-1401 Tel: +1.212.906.1200 Fax: +1.212.751.4864 www.lw.com FIRM / AFFILIATE OFFICES Beijing Moscow Boston Munich Brussels New York Century City Orange County Chicago Paris Dubai Riyadh D?sseldorf San Diego Frankfurt San Francisco Hamburg Seoul Hong Kong Shanghai Houston Silicon Valley London Singapore Los Angeles Tokyo Madrid Washington, D.C. Mil

July 28, 2021 S-1/A

As filed with the Securities and Exchange Commission on July 28, 2021.

S-1/A 1 tm2115679-15s1a.htm S-1/A As filed with the Securities and Exchange Commission on July 28, 2021. Registration No. 333-257791 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Amendment No. 2 to FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 IMMUNEERING CORPORATION (Exact name of registrant as specified in its charter) Delaware (State or other jurisdi

July 27, 2021 8-A12B

The description of our common stock contained in our Registration Statement on Form 8-A, filed with the SEC on July 27, 2021 and any amendment or report filed with the SEC for the purpose of updating the description.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-A FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 IMMUNEERING CORPORATION (Exact name of registrant as specified in its charter) Delaware 26-1976972 (State of incorporation or organization) (I.R.S. Employer Identification No.) 245 Main Street, Sec

July 27, 2021 CORRESP

July 27, 2021

CORRESP 1 filename1.htm July 27, 2021 Via EDGAR Transmission United States Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Mail Stop 4720 Washington, D.C. 20549 Attention: Alan Campbell Re: Immuneering Corporation Registration Statement on Form S-1 Filed July 9, 2021 Registration No. 333-257791 Dear Mr. Campbell: In accordance with Rule 461 of Regulation C of

July 27, 2021 CORRESP

[Signature Page Follows]

July 27, 2021 VIA EDGAR Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.

July 26, 2021 EX-10.13

Immuneering Corporation Non-Employee Director Compensation Program.

EX-10.13 17 tm2115679d11ex10-13.htm EXHIBIT 10.13 Exhibit 10.13 IMMUNEERING CORPORATION NON-EMPLOYEE DIRECTOR COMPENSATION PROGRAM Non-employee members of the board of directors (the “Board”) of Immuneering Corporation (the “Company”) shall receive cash and equity compensation as set forth in this Non-Employee Director Compensation Program (this “Program”). The cash and equity compensation describ

July 26, 2021 EX-10.12

Form of Indemnification Agreement by and among the Registrant and its directors and officers.

EX-10.12 16 tm2115679d11ex10-12.htm EXHIBIT 10.12 Exhibit 10.12 IMMUNEERING CORPORATION Indemnification Agreement THIS INDEMNIFICATION AGREEMENT (the “Agreement”) is made and entered into as of , 2021 between Immuneering Corporation, a Delaware corporation (the “Company”), and [Name] (“Indemnitee”). WITNESSETH THAT: WHEREAS, highly competent persons have become more reluctant to serve corporations

July 26, 2021 EX-10.5

Employment Agreement, dated July 23, 2021, by and between Biren Amin and Immuneering Corporation

EX-10.5 9 tm2115679d11ex10-5.htm EXHIBIT 10.5 Exhibit 10.5 Employment Agreement This Employment Agreement (this “Agreement”), dated as of July 23, 2021, is made by and between Immuneering Corporation, a Delaware corporation (together with any successor thereto, the “Company”), and Biren Amin (“Executive”) (collectively referred to herein as the “Parties” or individually referred to as a “Party”),

July 26, 2021 EX-3.3

Form of Amended and Restated Certificate of Incorporation of the Registrant (to be in effect upon the consummation of this offering).

Exhibit 3.3 AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF IMMUNEERING CORPORATION Immuneering Corporation (the ?Corporation?), a corporation organized and existing under the General Corporation Law of the State of Delaware (the ?DGCL?), does hereby certify as follows: 1. The name of the Corporation is Immuneering Corporation. The Corporation was incorporated under the name Immuneering Corpo

July 26, 2021 EX-3.4

Form of Amended and Restated Bylaws of the Registrant (to be in effect upon the consummation of this offering).

EX-3.4 5 tm2115679d11ex3-4.htm EXHIBIT 3.4 Exhibit 3.4 AMENDED AND RESTATED BYLAWS OF IMMUNEERING CORPORATION (a Delaware corporation) TABLE OF CONTENTS Page ARTICLE I - CORPORATE OFFICES 1 1.1 REGISTERED OFFICE 1 1.2 OTHER OFFICES 1 ARTICLE II - MEETINGS OF STOCKHOLDERS 1 2.1 PLACE OF MEETINGS 1 2.2 ANNUAL MEETING 2 2.3 SPECIAL MEETING 2 2.4 ADVANCE NOTICE PROCEDURES FOR BUSINESS BROUGHT BEFORE A

July 26, 2021 EX-10.8

Employment Agreement, dated July 23, 2021, by and between Benjamin J. Zeskind, Ph.D. and Immuneering Corporation

EX-10.8 12 tm2115679d11ex10-8.htm EXHIBIT 10.8 Exhibit 10.8 Employment Agreement This Employment Agreement (this “Agreement”), dated as of July 23, 2021, is made by and between Immuneering Corporation, a Delaware corporation (together with any successor thereto, the “Company”), and Benjamin Zeskind, Ph.D. (“Executive”) (collectively referred to herein as the “Parties” or individually referred to a

July 26, 2021 EX-10.10

Immuneering Corporation 2021 Incentive Award Plan and forms of award agreements thereunder.

EX-10.10 14 tm2115679d11ex10-10.htm EXHIBIT 10.10 Exhibit 10.10 IMMUNEERING CORPORATION 2021 INCENTIVE AWARD PLAN ARTICLE I. PURPOSE The Plan’s purpose is to enhance the Company’s ability to attract, retain and motivate persons who make (or are expected to make) important contributions to the Company by providing these individuals with equity ownership opportunities and/or equity-linked compensato

July 26, 2021 EX-4.1

Form of Specimen Stock Certificate evidencing the shares of Class A common stock (incorporated by reference to Exhibit 4.1 of the Company’s Registration Statement on Form S-1/A filed with the SEC on July 26, 2021).

Exhibit 4.1 NUMBER IM SHARES CLASS A COMMON STOCK this Certifies that: INCORPORATED UNDER THE LAWS OF THE STATE OF DELAWARE SEE REVERSE FOR CERTAIN DEFINITIONS CUSIP45254E 10 7 SPECIMEN - NOT NEGOTIABLE is the owner of FULLY PAID AND NON-ASSESSABLE SHARES OF CLASS A COMMON STOCK OF $0.001 PAR VALUE EACH OF ImmuneerIng CorporatIon transferable on the books of the Corporation by the holder hereof in

July 26, 2021 EX-3.1

Fourth Amended and Restated Certificate of Incorporation of the Registrant, as amended (currently in effect).

Exhibit 3.1 FOURTH AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF IMMUNEERING CORPORATION (Pursuant to Sections 242 and 245 of the General Corporation Law of the State of Delaware) Immuneering Corporation, a corporation organized and existing under and by virtue of the provisions of the General Corporation Law of the State of Delaware (the ?General Corporation Law?), DOES HEREBY CERTIFY: 1.

July 26, 2021 EX-10.7

Employment Agreement, dated July 23, 2021, by and between Scott Barrett, M.D. and Immuneering Corporation

Exhibit 10.7 Employment Agreement This Employment Agreement (this “Agreement”), dated as of July 23, 2021, is made by and between Immuneering Corporation, a Delaware corporation (together with any successor thereto, the “Company”), and Scott Barrett, M.D. (“Executive”) (collectively referred to herein as the “Parties” or individually referred to as a “Party”), and will become effective, if at all,

July 26, 2021 EX-10.6

Employment Agreement, dated July 23, 2021, by and between Brett Hall, Ph.D. and Immuneering Corporation

Exhibit 10.6 Employment Agreement This Employment Agreement (this ?Agreement?), dated as of July 23, 2021, is made by and between Immuneering Corporation, a Delaware corporation (together with any successor thereto, the ?Company?), and Brett Hall, Ph.D. (?Executive?) (collectively referred to herein as the ?Parties? or individually referred to as a ?Party?), and will become effective, if at all, u

July 26, 2021 EX-10.11

Immuneering Corporation 2021 Employee Stock Purchase Plan.

Exhibit 10.11 IMMUNEERING CORPORATION 2021 EMPLOYEE STOCK PURCHASE PLAN ARTICLE I. PURPOSE The purposes of this Immuneering Corporation 2021 Employee Stock Purchase Plan (as it may be amended or restated from time to time, the “Plan”) are to assist Eligible Employees of Immuneering Corporation, a Delaware corporation (the “Company”), and its Designated Subsidiaries in acquiring a stock ownership i

July 26, 2021 EX-1.1

Form of Underwriting Agreement.

Exhibit 1.1 [·] Shares IMMUNEERING CORPORATION COMMON STOCK (PAR VALUE $0.001 PER SHARE) UNDERWRITING AGREEMENT [·], 2021 1 [·], 2021 Morgan Stanley & Co. LLC Jefferies LLC Cowen and Company, LLC As Representatives of the several Underwriters named in Schedule I hereto c/o Morgan Stanley & Co. LLC 1585 Broadway New York, New York 10036 c/o Jefferies LLC 520 Madison Avenue, 10th Floor New York, New

July 26, 2021 EX-21.1

List of Subsidiaries of the Registrant.

Exhibit 21.1 Subsidiary of Immuneering Corporation Subsidiary Jurisdiction Immuneering Securities Corporation Massachusetts

July 26, 2021 S-1/A

As filed with the Securities and Exchange Commission on July 26, 2021.

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on July 26, 2021.

July 26, 2021 EX-4.2

Amended and Restated Investors’ Rights Agreement, dated December 21, 2020, by and among the Registrant and the other parties thereto.

Exhibit 4.2 Execution Version AMENDED AND RESTATED INVESTORS? RIGHTS AGREEMENT THIS AMENDED AND RESTATED INVESTORS? RIGHTS AGREEMENT (this ?Agreement?), is made as of the 21st day of December, 2020, by and among Immuneering Corporation, a Delaware corporation (the ?Company?), and each of the investors listed on Schedule A hereto, each of which is referred to in this Agreement as an ?Investor? and

July 26, 2021 EX-10.9

Employment Agreement, dated July 23, 2021, by and between Michael D. Bookman and Immuneering Corporation

Exhibit 10.9 Employment Agreement This Employment Agreement (this “Agreement”), dated as of July 23, 2021, is made by and between Immuneering Corporation, a Delaware corporation (together with any successor thereto, the “Company”), and Michael Bookman (“Executive”) (collectively referred to herein as the “Parties” or individually referred to as a “Party”), and will become effective, if at all, upo

July 14, 2021 CORRESP

CONFIDENTIAL TREATMENT HAS BEEN REQUESTED BY IMMUNEERING CORPORATION

1271 Avenue of the Americas New York, New York 10020-1401 Tel: +1.212.906.1200 Fax: +1.212.751.4864 www.lw.com FIRM / AFFILIATE OFFICES Beijing Moscow Boston Munich Brussels New York Century City Orange County Chicago Paris Dubai Riyadh July 14, 2021 D?sseldorf San Diego Frankfurt San Francisco Hamburg Seoul Hong Kong Shanghai Houston Silicon Valley London Singapore Los Angeles Tokyo Madrid Washin

July 9, 2021 S-1

Power of Attorney (included on signature page).

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on July 9, 2021.

July 9, 2021 EX-10.3

Advisory Agreement, dated September 17, 2019, by and between PEF LLC and the Registrant.

EX-10.3 6 tm2115679d7ex10-3.htm EXHIBIT 10.3 Exhibit 10.3 September 17, 2019 PEF LLC Subject: Advisor to Immuneering Corporation Dear PEF LLC, Immuneering Corporation (the “Company”) is pleased to invite you to serve as an Advisor to the Company. This letter will set forth the terms and conditions of your participation as an advisor to the Company commencing on the date hereof (the “Effective Date

July 9, 2021 EX-10.2

Master Services Agreement, dated August 5, 2019, by and between Bioarkive LLC and the Registrant.

EX-10.2 5 tm2115679d7ex10-2.htm EXHIBIT 10.2 Exhibit 10.2 (1) BioArkive, LLC - and - (2) Immuneering Corporation MASTER SERVICES AGREEMENT BioArkive & Immuneering 1/11 MASTER SERVICES AGREEMENT This Master Services Agreement (“Agreement”), effective as of August 5th, 2019 (“Effective Date”), is made by and between Bioarkive LLC, a limited liability company under the laws of California, USA, having

July 9, 2021 EX-3.1

Fourth Amended and Restated Certificate of Incorporation of the Registrant (currently in effect).

Exhibit 3.1 FOURTH AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF IMMUNEERING CORPORATION (Pursuant to Sections 242 and 245 of the General Corporation Law of the State of Delaware) Immuneering Corporation, a corporation organized and existing under and by virtue of the provisions of the General Corporation Law of the State of Delaware (the “General Corporation Law”), DOES HEREBY CERTIFY: 1.

July 9, 2021 CORRESP

1271 Avenue of the Americas

1271 Avenue of the Americas New York, New York 10020-1401 Tel: +1.212.906.1200 Fax: +1.212.751.4864 www.lw.com FIRM / AFFILIATE OFFICES July 9, 2021 VIA EDGAR AND HAND DELIVERY Beijing Boston Brussels Century City Chicago Dubai D?sseldorf Frankfurt Hamburg Hong Kong Houston London Los Angeles Madrid Milan Moscow Munich New York Orange County Paris Riyadh San Diego San Francisco Seoul Shanghai Sili

July 9, 2021 EX-10.5

Immuneering Corporation Long Term Incentive Plan and form of option agreement thereunder.

EX-10.5 8 tm2115679d7ex10-5.htm EXHIBIT 10.5 Exhibit 10.5 IMMUNEERING CORPORATION Long Term Incentive Plan 1. Purpose. The purpose of the Immuneering Corporation Long Term Incentive Plan (the or this “Plan”) is to provide a means through which Immuneering Corporation, a Delaware corporation (the “Company”), and its Subsidiaries may attract and retain able persons as employees, directors and consul

July 9, 2021 EX-10.4

Immuneering Corporation 2008 Stock Incentive Plan and form of option agreement thereunder.

EX-10.4 7 tm2115679d7ex10-4.htm EXHIBIT 10.4 Exhibit 10.4 IMMUNEERING CORPORATION 2008 STOCK INCENTIVE PLAN 1. Purpose The purpose of this 2008 Stock Incentive Plan (the “Plan”) of Immuneering Corporation, a Delaware corporation (the “Company”), is to advance the interests of the Company’s stockholders by enhancing the Company’s ability to attract, retain and motivate persons who are expected to m

July 9, 2021 EX-3.2

Third Amended and Restated By-Laws of the Registrant (currently in effect).

Exhibit 3.2 Execution Version THIRD AMENDED AND RESTATED BY-LAWS OF IMMUNEERING CORPORATION TABLE OF CONTENTS Page ARTICLE I STOCKHOLDERS 1.1 Place of Meetings 1 1.2 Annual Meeting 1 1.3 Special Meetings 1 1.4 Notice of Meetings 1 1.5 Voting List 1 1.6 Quorum 2 1.7 Adjournments 2 1.8 Voting and Proxies 2 1.9 Action at Meeting 3 1.10 Conduct of Meetings 3 1.11 Action without Meeting 4 ARTICLE II DI

July 9, 2021 EX-10.1

Amended and Restated Investors’ Rights Agreement, dated December 21, 2020, by and among the Registrant and the other parties thereto.

Exhibit 10.1 Execution Version AMENDED AND RESTATED INVESTORS? RIGHTS AGREEMENT THIS AMENDED AND RESTATED INVESTORS? RIGHTS AGREEMENT (this ?Agreement?), is made as of the 21st day of December, 2020, by and among Immuneering Corporation, a Delaware corporation (the ?Company?), and each of the investors listed on Schedule A hereto, each of which is referred to in this Agreement as an ?Investor? and

June 21, 2021 EX-10.4

IMMUNEERING CORPORATION Long Term Incentive Plan

EX-10.4 5 filename5.htm Exhibit 10.4 IMMUNEERING CORPORATION Long Term Incentive Plan 1. Purpose. The purpose of the Immuneering Corporation Long Term Incentive Plan (the or this “Plan”) is to provide a means through which Immuneering Corporation, a Delaware corporation (the “Company”), and its Subsidiaries may attract and retain able persons as employees, directors and consultants and to provide

June 21, 2021 EX-10.3

IMMUNEERING CORPORATION 2008 STOCK INCENTIVE PLAN

EX-10.3 4 filename4.htm Exhibit 10.3 IMMUNEERING CORPORATION 2008 STOCK INCENTIVE PLAN 1. Purpose The purpose of this 2008 Stock Incentive Plan (the “Plan”) of Immuneering Corporation, a Delaware corporation (the “Company”), is to advance the interests of the Company’s stockholders by enhancing the Company’s ability to attract, retain and motivate persons who are expected to make important contrib

June 21, 2021 EX-10.2

(1) BioArkive, LLC - and - (2) Immuneering Corporation MASTER SERVICES AGREEMENT

Exhibit 10.2 (1) BioArkive, LLC - and - (2) Immuneering Corporation MASTER SERVICES AGREEMENT BioArkive & Immuneering 1/11 MASTER SERVICES AGREEMENT This Master Services Agreement (?Agreement?), effective as of August 5th, 2019 (?Effective Date?), is made by and between Bioarkive LLC, a limited liability company under the laws of California, USA, having its registered offices and principal place o

June 21, 2021 DRS/A

As confidentially submitted to the Securities and Exchange Commission on June 21, 2021.

TABLE OF CONTENTS As confidentially submitted to the Securities and Exchange Commission on June 21, 2021.

June 21, 2021 DRSLTR

1271 Avenue of the Americas

1271 Avenue of the Americas New York, New York 10020-1401 Tel: +1.212.906.1200 Fax: +1.212.751.4864 www.lw.com FIRM / AFFILIATE OFFICES Beijing Moscow Boston Munich Brussels New York Century City Orange County Chicago Paris Dubai Riyadh June 21, 2021 D?sseldorf San Diego Frankfurt San Francisco Hamburg Seoul Hong Kong Shanghai Houston Silicon Valley VIA EDGAR AND HAND DELIVERY London Singapore Los

June 21, 2021 EX-10.1

AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT

Exhibit 10.1 Execution Version AMENDED AND RESTATED INVESTORS? RIGHTS AGREEMENT THIS AMENDED AND RESTATED INVESTORS? RIGHTS AGREEMENT (this ?Agreement?), is made as of the 21st day of December, 2020, by and among Immuneering Corporation, a Delaware corporation (the ?Company?), and each of the investors listed on Schedule A hereto, each of which is referred to in this Agreement as an ?Investor? and

May 13, 2021 EX-10.1

AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT

EX-10.1 2 filename2.htm Exhibit 10.1 Execution Version AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT THIS AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT (this “Agreement”), is made as of the 21st day of December, 2020, by and among Immuneering Corporation, a Delaware corporation (the “Company”), and each of the investors listed on Schedule A hereto, each of which is referred to in this Agreem

May 13, 2021 EX-10.6

EXHIBIT A: INVENTION AND NON-DISCLOSURE AGREEMENT

EX-10.6 5 filename5.htm Exhibit 10.6 Confidential Ben Zeskind, PhD Immuneering Corporation (617)-500-8080 ext. 121 [email protected] October 24, 2019 Brett Hall, PhD Dear Brett: On behalf of Immuneering Corporation (the “Company”), I am pleased to set forth the terms of your employment with the Company: 1. You will be employed to serve on a full-time basis as Chief Scientific Officer effect

May 13, 2021 EX-10.5

EMPLOYEE PROPRIETARY INFORMATION AND INVENTIONS ASSIGNMENT AGREEMENT

EX-10.5 4 filename4.htm Exhibit 10.5 Confidential Ben Zeskind, PhD, MBA Immuneering Corporation (617) 500-8080 ext. 121 (617) 694-3782 (cell) [email protected] March 5, 2021 Biren N. Amin 3 Victoria Place Holmdel, NJ 07733 847-609-3735 (cell) [email protected] Dear Biren: On behalf of Immuneering Corporation (the “Company”), I am pleased to set forth the terms of your employment with the Com

May 13, 2021 EX-10.2

(1) BioArkive, LLC - and - (2) Immuneering Corporation MASTER SERVICES AGREEMENT

EX-10.2 3 filename3.htm Exhibit 10.2 (1) BioArkive, LLC - and - (2) Immuneering Corporation MASTER SERVICES AGREEMENT BioArkive & Immuneering 1/11 MASTER SERVICES AGREEMENT This Master Services Agreement (“Agreement”), effective as of August 5th, 2019 (“Effective Date”), is made by and between Bioarkive LLC, a limited liability company under the laws of California, USA, having its registered offic

May 13, 2021 DRS

As confidentially submitted to the Securities and Exchange Commission on May 13, 2021.

DRS 1 filename1.htm TABLE OF CONTENTS As confidentially submitted to the Securities and Exchange Commission on May 13, 2021. Registration No. 333-        UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 IMMUNEERING CORPORATION (Exact name of registrant as specified in its charter) Delaware (State or other juris

May 13, 2021 EX-10.7

EXHIBIT A: INVENTION AND NON-DISCLOSURE AGREEMENT

Exhibit 10.7 Confidential Ben Zeskind, PhD Immuneering Corporation (617)-500-8080 ext. 121 [email protected] October 11, 2019 Scott Barrett, M.D. 8101 Arment Drive Glen Mills, PA 19342 (267) 218-6152 [email protected] Dear Scott: On behalf of Immuneering Corporation (the ?Company?), I am pleased to set forth the terms of your employment with the Company: 1. You will be employed to serve on

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