| Акции выдающиеся | 108,332,218 shares |
| Инсайдерские акции | 30 414 323 shares |
| Инсайдерская собственность | 28,08 % |
| Всего инсайдеров | 48 |
Оценка инсайдерских настроений
Индекс настроений инсайдеров показывает, какие компании покупают корпоративные инсайдеры.
Это результат сложной многофакторной количественной модели, которая идентифицирует компании с самым высоким уровнем накопления инсайдерской информации. Модель оценки использует комбинацию чистого количества инсайдеров, купивших акции за предыдущие 90 дней, общего количества купленных акций в процентах от находящихся в обращении и общего количества акций, принадлежащих инсайдерам. Число варьируется от 0 до 100, причем более высокие цифры указывают на более высокий уровень накопления по сравнению с аналогами, а 50 — это среднее значение.
Частота обновлений: ежедневно
Оценка настроений офицеров
Оценка настроений руководителей показывает, что компании покупаются руководителями корпораций.
По определению, корпоративные должностные лица являются корпоративными инсайдерами, но в отличие от некоторых других инсайдеров (10% акционеров и членов совета директоров), должностные лица работают в компании ежедневно и используют свои собственные деньги при торговле . (10% акционеров и членов совета директоров часто являются управляющими фондами, управляющими деньгами других людей.) Таким образом, инсайдерские сделки, совершаемые должностными лицами, гораздо более значимы, и к ним следует относиться соответствующим образом.
Как и оценка инсайдерских настроений, оценка настроений сотрудников является результатом сложной многофакторной количественной модели, которая идентифицирует компании с самым высоким уровнем накопления сотрудников.
Частота обновлений: ежедневно
Ключевые инсайдерские показатели
На этой карточке показано место компании по различным инсайдерским показателям. Процентильный рейтинг показывает, как эта компания сравнивается с другими компаниями на рынках США. Более высокие рейтинги указывают на лучшие ситуации.
Например, общепринято, что инсайдерские покупки являются положительным показателем, поэтому компании с большим количеством инсайдерских покупок будут иметь более высокий рейтинг, чем компании с меньшим количеством инсайдерских покупок (или даже с меньшим количеством инсайдерских продаж).
Процент акций, купленных инсайдерами (ранг)
0.000 %( )
5370 out of 11244Процент акций, купленных инсайдерами, — это общее количество акций, купленных инсайдерами, минус общее количество акций, проданных инсайдерами за последние 90 дней, разделенное на общее количество акций в обращении и умноженное на 100.
График инсайдерской торговли
Инсайдерские сделки (Aclaris Therapeutics, Inc.) показаны на следующей диаграмме. Инсайдеры — это должностные лица, директора или крупные инвесторы компании. В целом инсайдерам запрещено совершать сделки в своих компаниях на основе существенной, закрытой информации. Это не означает, что для них незаконно совершать какие-либо сделки в своих собственных компаниях. Однако они должны сообщать обо всех сделках в SEC через форму 4.
Список инсайдеров и показатели прибыльности
В этой таблице показан список известных инсайдеров, который создается автоматически на основе документов, раскрытых в SEC. Помимо имен, последней должности и указания директора, должностного лица или владельца 10% акций, мы предоставляем информацию о последних раскрытых активах. Кроме того, когда это возможно, мы предоставляем инсайдерам исторические результаты торговли. Исторические результаты торговли представляют собой средневзвешенное значение результатов фактических транзакций покупки на открытом рынке, совершенных инсайдером. Для получения дополнительной информации о том, как это рассчитывается, посмотрите этот вебинар на YouTube.
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| Инсайдер | Средняя прибыль (%) | Акции В собственности |
Расколоть Скорректировано |
|---|---|---|---|
|
Srinivas Akkaraju
10% Owner -
|
2 289 480 | 2 289 480 | |
| Kamil Ali-Jackson Chief Legal Officer - [O] | 160 214 | 160 214 | |
| Kevin Balthaser Chief Financial Officer - [O] | 92 608 | 92 608 | |
| Rick Bierly | 8 000 | ||
| Albert Cha Director - [D] | 4 191 397 | 4 191 397 | |
| Gail Cawkwell Chief Medical Officer - [O] | 9 593 | 9 593 | |
|
Management Co Deerfield
10% Owner -
|
3 159 165 | 3 159 165 | |
|
Deerfield Partners, L.p.
10% Owner -
|
3 159 165 | 3 159 165 | |
|
Deerfield Mgmt L.P.
10% Owner -
|
3 159 165 | 3 159 165 | |
|
Deerfield Special Situations Fund, L.P.
10% Owner -
|
3 159 165 | 3 159 165 | |
|
FMR LLC / Fidelity Management & Research
10% Owner -
|
326 917 | 326 917 | |
| Brett Fair Chief Commercial Officer - [O] | 10 582 | 10 582 | |
|
James E Flynn
10% Owner -
|
3 159 165 | 3 159 165 | |
|
Foresite Capital Fund III, L.P.
10% Owner -
|
8 276 | 8 276 | |
|
Foresite Capital Fund IV, L.P.
10% Owner -
|
8 276 | 8 276 | |
|
Foresite Capital Fund V, L.P.
10% Owner -
|
8 276 | 8 276 |
| Инсайдер | Средняя прибыль (%) | Акции В собственности |
Расколоть Скорректировано |
|---|---|---|---|
|
Foresite Capital Management III, LLC
10% Owner -
|
8 276 | 8 276 | |
|
Foresite Capital Management IV, LLC
10% Owner -
|
8 276 | 8 276 | |
|
Foresite Capital Management V, LLC
10% Owner -
|
8 276 | 8 276 | |
| Maxine Gowen Director - [D] | 21 754 | 21 754 | |
| Gordon David N. Chief Medical Officer - [O] | 147 447 | 147 447 | |
|
James Healy
10% Owner -
|
2 289 480 | 2 289 480 | |
| Humphries William D. Director - [D] | 33 525 | 33 525 | |
|
Peter Kolchinsky
10% Owner -
|
2 102 169 | 2 102 169 | |
|
Braden Michael Leonard
10% Owner -
|
14 250 000 | 14 250 000 | |
| James Loerop Chief Business Officer - [O] | 103 306 | 103 306 | |
| Vincent Milano Director - [D] | 17 316 | 17 316 | |
| Manion Douglas J. Pres and CEO, Director - [D] [O] | 41 813 | 41 813 | |
| Anand Mehra Director - [D] | 714 823 | 714 823 | |
| Molineaux Christopher P. Director - [D] | 57 956 | 57 956 | |
| Joseph Monahan Chief Scientific Officer - [O] | 265 855 | 265 855 | |
|
Michael Powell
10% Owner -
|
2 289 480 | 2 289 480 |
| Инсайдер | Средняя прибыль (%) | Акции В собственности |
Расколоть Скорректировано |
|---|---|---|---|
| Christopher Powala Chief Reg & Develop Officer - [O] | 141 729 | 141 729 | |
| Andrew Kenneth William Powell Director - [D] | 33 523 | 33 523 | |
|
Ra Capital Management, Llc
10% Owner -
|
2 102 169 | 2 102 169 | |
|
RA Capital Healthcare Fund LP
10% Owner -
|
2 102 169 | 2 102 169 | |
| Reasons Bryan M. Director - [D] | 28 732 | 28 732 | |
| Frank Ruffo Chief Financial Officer - [O] | 201 883 | 201 883 | |
| Andrew N Schiff Director - [D] | 13 960 | 13 960 | |
| Stuart Shanler Chief Scientific Officer - [O] | 272 047 | 272 047 | |
|
Sofinnova Management VIII, L.L.C.
10% Owner -
|
2 289 480 | 2 289 480 | |
|
Sofinnova Venture Partners VIII, L.P.
10% Owner -
|
2 289 480 | 2 289 480 | |
|
Tananbaum James B.
10% Owner -
|
8 276 | 8 276 | |
| Tullman Stephen A. Director - [D] | 177 457 | 177 457 | |
|
Vivo Ventures Vii, Llc
10% Owner -
|
60 972 | 60 972 | |
|
Vivo Ventures Fund VII, L.P.
10% Owner -
|
60 972 | 60 972 | |
|
Vivo Ventures VII Affiliates Fund, L.P.
10% Owner -
|
60 972 | 60 972 | |
| Neal Walker CEO, Director - [D] [O] | 1 479 824 | 1 479 824 |
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История инсайдерских покупок – анализ краткосрочной прибыли
В этом разделе мы анализируем прибыльность каждой незапланированной инсайдерской покупки на открытом рынке, совершенной в ACRS / Aclaris Therapeutics, Inc.. Этот анализ помогает понять, стабильно ли инсайдер генерирует аномальную доходность, и стоит ли за ним следить. Этот анализ рассчитан на один год после каждой сделки, и результаты теоретические .
В следующей таблице показаны самые последние покупки на открытом рынке, которые не были частью автоматического торгового плана.
Скорректированная цена — это цена, скорректированная на дробление. Скорректированные акции — это акции, скорректированные на дробление.
История инсайдерских продаж – анализ краткосрочных потерь
В этом разделе мы анализируем возможность избежать краткосрочных потерь при каждой незапланированной инсайдерской продаже на открытом рынке, совершенной в ACRS / Aclaris Therapeutics, Inc.. Последовательная модель избегания потерь может указывать на то, что будущие сделки купли-продажи могут предсказать снижение цены. Этот анализ рассчитан на один год после каждой сделки, и результаты теоретические .
В следующей таблице показаны самые последние продажи на открытом рынке, которые не были частью автоматического торгового плана.
Скорректированная цена — это цена, скорректированная на дробление. Скорректированные акции — это акции, скорректированные на дробление.
История транзакций
Нажмите на значок ссылки, чтобы просмотреть полную историю транзакций. Транзакции, зарегистрированные в рамках плана автоматической торговли 10b5-1, будут отмечены знаком X в столбце 10b-5.
| Файл Дата |
Торговля Дата |
Форма | Инсайдер | Бегущая строка | Название безопасности | Код | Прямой | Упражнение Цена |
Единица Цена |
Единицы Измененный |
Ценить Изменено (1К) |
Оставшийся Параметры |
Оставшийся Акции |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-06-09 | 2025-06-06 | 4 | Molineaux Christopher P. | ACRS | Common Stock | D | 4 793 | 57 956 | ||||||
| 2025-06-09 | 2025-06-06 | 4 | GOWEN MAXINE | ACRS | Common Stock | D | 4 793 | 21 754 | ||||||
| 2025-06-09 | 2025-06-06 | 4 | Humphries William D. | ACRS | Common Stock | D | 4 793 | 33 525 | ||||||
| 2025-06-09 | 2025-06-06 | 4 | Mehra Anand | ACRS | Common Stock | D | 4 793 | 714 823 | ||||||
| 2025-06-09 | 2025-06-06 | 4 | MILANO VINCENT | ACRS | Common Stock | D | 4 793 | 17 316 | ||||||
| 2025-06-09 | 2025-06-06 | 4 | SCHIFF ANDREW N | ACRS | Common Stock | D | 4 793 | 13 960 | ||||||
| 2025-05-05 | 2025-05-01 | 4 | Walker Neal | ACRS | Common Stock | D | 1,3800 | -2 975 | -4 | 1 479 824 | ||||
| 2025-05-05 | 2025-05-01 | 4 | Walker Neal | ACRS | Common Stock | D | 9 467 | 1 482 799 | ||||||
| 2025-04-03 | 2025-04-01 | 4 | Walker Neal | ACRS | Common Stock | D | 1,4800 | -3 042 | -5 | 1 473 332 | ||||
| 2025-04-03 | 2025-04-01 | 4 | Walker Neal | ACRS | Common Stock | D | 9 467 | 1 476 374 | ||||||
| 2025-03-04 | 2025-03-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 1,9900 | -27 258 | -54 | 265 662 | ||||
| 2025-03-04 | 2025-03-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 10 925 | 292 920 | ||||||
| 2025-03-04 | 2025-03-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 50 000 | 281 995 | ||||||
| 2025-03-04 | 2025-03-01 | 4 | Walker Neal | ACRS | Common Stock | D | 1,9900 | -3 277 | -7 | 1 466 907 | ||||
| 2025-03-04 | 2025-03-01 | 4 | Walker Neal | ACRS | Common Stock | D | 9 466 | 1 470 184 | ||||||
| 2025-03-04 | 2025-03-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 1,9900 | -727 | -1 | 92 608 | ||||
| 2025-03-04 | 2025-03-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 2 375 | 93 335 | ||||||
| 2025-03-04 | 2025-03-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 1 100 | 90 960 | ||||||
| 2025-02-04 | 2025-02-01 | 4 | Walker Neal | ACRS | Common Stock | D | 2,4800 | -3 559 | -9 | 1 460 718 | ||||
| 2025-02-04 | 2025-02-01 | 4 | Walker Neal | ACRS | Common Stock | D | 9 467 | 1 464 277 | ||||||
| 2025-02-04 | 2025-02-01 | 4 | Loerop James | ACRS | Common Stock | D | 2,4800 | -15 447 | -38 | 103 306 | ||||
| 2025-02-04 | 2025-02-01 | 4 | Loerop James | ACRS | Common Stock | D | 14 750 | 118 753 | ||||||
| 2025-02-04 | 2025-02-01 | 4 | Loerop James | ACRS | Common Stock | D | 7 500 | 104 003 | ||||||
| 2025-02-04 | 2025-02-01 | 4 | Loerop James | ACRS | Common Stock | D | 11 250 | 96 503 | ||||||
| 2025-02-04 | 2025-02-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 2,4800 | -5 816 | -14 | 89 860 | ||||
| 2025-02-04 | 2025-02-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 14 750 | 95 676 | ||||||
| 2025-02-04 | 2025-02-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 2,4800 | -11 317 | -28 | 231 995 | ||||
| 2025-02-04 | 2025-02-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 14 750 | 243 312 | ||||||
| 2025-02-04 | 2025-02-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 7 500 | 228 562 | ||||||
| 2025-01-03 | 2025-01-02 | 4 | Walker Neal | ACRS | Common Stock | D | 2,4800 | -13 532 | -34 | 1 454 810 | ||||
| 2025-01-03 | 2025-01-02 | 4 | Walker Neal | ACRS | Common Stock | D | 29 149 | 1 468 342 | ||||||
| 2025-01-03 | 2025-01-01 | 4 | Walker Neal | ACRS | Common Stock | D | 2,4800 | -3 904 | -10 | 1 439 193 | ||||
| 2025-01-03 | 2025-01-01 | 4 | Walker Neal | ACRS | Common Stock | D | 9 467 | 1 443 097 | ||||||
| 2025-01-03 | 2025-01-02 | 4 | Loerop James | ACRS | Common Stock | D | 2,4800 | -8 575 | -21 | 85 253 | ||||
| 2025-01-03 | 2025-01-02 | 4 | Loerop James | ACRS | Common Stock | D | 18 150 | 93 828 | ||||||
| 2025-01-03 | 2024-12-31 | 4 | Loerop James | ACRS | Common Stock | D | 2,4800 | -32 089 | -80 | 75 678 | ||||
| 2025-01-03 | 2024-12-31 | 4 | Loerop James | ACRS | Common Stock | D | 73 750 | 107 767 | ||||||
| 2025-01-03 | 2025-01-02 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 2,4800 | -5 059 | -13 | 80 926 | ||||
| 2025-01-03 | 2025-01-02 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 13 200 | 85 985 | ||||||
| 2025-01-03 | 2025-01-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 2,4800 | -2 430 | -6 | 72 785 | ||||
| 2025-01-03 | 2025-01-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 7 500 | 75 215 | ||||||
| 2025-01-03 | 2024-12-31 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 2,4800 | -30 732 | -76 | 67 715 | ||||
| 2025-01-03 | 2024-12-31 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 73 750 | 98 447 | ||||||
| 2025-01-03 | 2025-01-02 | 4 | Monahan Joseph | ACRS | Common Stock | D | -8 914 | 221 062 | ||||||
| 2025-01-03 | 2025-01-02 | 4 | Monahan Joseph | ACRS | Common Stock | D | 17 380 | 229 976 | ||||||
| 2025-01-03 | 2024-12-31 | 4 | Monahan Joseph | ACRS | Common Stock | D | -32 937 | 212 596 | ||||||
| 2025-01-03 | 2024-12-31 | 4 | Monahan Joseph | ACRS | Common Stock | D | 73 750 | 245 533 | ||||||
| 2024-12-12 | 2024-12-10 | 4 | Monahan Joseph | ACRS | Common Stock | D | -15 000 | 171 783 | ||||||
| 2024-12-06 | 2024-12-04 | 4 | Walker Neal | ACRS | Common Stock | D | 3,7600 | -68 343 | -257 | 1 433 630 | ||||
| 2024-12-06 | 2024-12-04 | 4 | Walker Neal | ACRS | Common Stock | D | 1,5200 | 118 840 | 181 | 1 501 973 | ||||
| 2024-12-03 | 2024-12-01 | 4 | Walker Neal | ACRS | Common Stock | D | 4,0700 | -2 721 | -11 | 1 383 133 | ||||
| 2024-12-03 | 2024-12-01 | 4 | Walker Neal | ACRS | Common Stock | D | 9 466 | 1 385 854 | ||||||
| 2024-11-20 | 2024-11-19 | 4 | Mehra Anand | ACRS | Common Stock | D | 2,2500 | 666 666 | 1 500 | 710 030 | ||||
| 2024-11-05 | 2024-11-01 | 4 | Walker Neal | ACRS | Common Stock | D | 2,0900 | -2 721 | -6 | 1 376 388 | ||||
| 2024-11-05 | 2024-11-01 | 4 | Walker Neal | ACRS | Common Stock | D | 9 467 | 1 379 109 | ||||||
| 2024-10-03 | 2024-10-01 | 4 | Walker Neal | ACRS | Common Stock | D | 1,1800 | -2 722 | -3 | 1 369 642 | ||||
| 2024-10-03 | 2024-10-01 | 4 | Walker Neal | ACRS | Common Stock | D | 9 467 | 1 372 364 | ||||||
| 2024-09-04 | 2024-09-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 1,1800 | -286 | -0 | 24 697 | ||||
| 2024-09-04 | 2024-09-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 1 000 | 24 983 | ||||||
| 2024-09-04 | 2024-09-01 | 4 | Walker Neal | ACRS | Common Stock | D | 1,1800 | -2 722 | -3 | 1 362 897 | ||||
| 2024-09-04 | 2024-09-01 | 4 | Walker Neal | ACRS | Common Stock | D | 9 466 | 1 365 619 | ||||||
| 2024-08-13 | 2024-08-09 | 4 | Walker Neal | ACRS | Common Stock | D | 0,7200 | 43 548 | 31 | 1 356 153 | ||||
| 2024-08-05 | 2024-08-01 | 4 | Walker Neal | ACRS | Common Stock | D | 1,3200 | -2 722 | -4 | 1 312 605 | ||||
| 2024-08-05 | 2024-08-01 | 4 | Walker Neal | ACRS | Common Stock | D | 9 467 | 1 315 327 | ||||||
| 2024-08-05 | 2024-08-05 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P | ACRS | Common Stock | I | 1,2443 | 206 025 | 256 | 14 250 000 | ||||
| 2024-08-05 | 2024-08-02 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ACRS | Common Stock | I | 1,2916 | 167 544 | 216 | 14 043 975 | ||||
| 2024-07-31 | 2024-07-31 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P | ACRS | Common Stock | I | 1,3264 | 100 000 | 133 | 13 876 421 | ||||
| 2024-07-31 | 2024-07-30 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ACRS | Common Stock | I | 1,3030 | 173 730 | 226 | 13 776 421 | ||||
| 2024-07-22 | 2024-07-22 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P | ACRS | Common Stock | I | 1,3297 | 17 716 | 24 | 13 602 691 | ||||
| 2024-07-22 | 2024-07-19 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P | ACRS | Common Stock | I | 1,3000 | 6 689 | 9 | 13 584 975 | ||||
| 2024-07-22 | 2024-07-18 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ACRS | Common Stock | I | 1,3011 | 130 317 | 170 | 13 578 286 | ||||
| 2024-07-05 | 2024-07-05 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P | ACRS | Common Stock | I | 1,1489 | 123 017 | 141 | 13 447 969 | ||||
| 2024-07-05 | 2024-07-03 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P | ACRS | Common Stock | I | 1,1590 | 143 288 | 166 | 13 324 952 | ||||
| 2024-07-05 | 2024-07-02 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ACRS | Common Stock | I | 1,1440 | 86 092 | 98 | 13 181 664 | ||||
| 2024-07-03 | 2024-07-01 | 4 | Walker Neal | ACRS | Common Stock | D | 1,1500 | -2 722 | -3 | 1 305 860 | ||||
| 2024-07-03 | 2024-07-01 | 4 | Walker Neal | ACRS | Common Stock | D | 9 467 | 1 308 582 | ||||||
| 2024-07-01 | 2024-07-01 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P | ACRS | Common Stock | I | 1,1373 | 107 434 | 122 | 13 095 572 | ||||
| 2024-07-01 | 2024-06-28 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P | ACRS | Common Stock | I | 1,1300 | 400 000 | 452 | 12 988 134 | ||||
| 2024-07-01 | 2024-06-28 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P | ACRS | Common Stock | I | 1,1193 | 801 000 | 897 | 12 588 134 | ||||
| 2024-07-01 | 2024-06-27 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ACRS | Common Stock | I | 1,1546 | 235 000 | 271 | 11 787 134 | ||||
| 2024-06-18 | 2024-06-18 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P | ACRS | Common Stock | I | 1,1301 | 50 000 | 57 | 11 552 134 | ||||
| 2024-06-18 | 2024-06-17 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P | ACRS | Common Stock | I | 1,1300 | 150 000 | 169 | 11 502 134 | ||||
| 2024-06-18 | 2024-06-14 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ACRS | Common Stock | I | 1,1658 | 345 000 | 402 | 11 352 134 | ||||
| 2024-06-13 | 2024-06-13 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ACRS | Common Stock | I | 1,1500 | 500 000 | 575 | 11 007 134 | ||||
| 2024-06-13 | 2024-06-13 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ACRS | Common Stock | I | 1,1445 | 28 621 | 33 | 10 507 134 | ||||
| 2024-06-13 | 2024-06-12 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ACRS | Common Stock | I | 1,1400 | 82 579 | 94 | 10 478 513 | ||||
| 2024-06-13 | 2024-06-11 | 4 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ACRS | Common Stock | I | 1,0800 | 1 000 000 | 1 080 | 10 395 934 | ||||
| 2024-06-04 | 2024-06-01 | 4 | SCHIFF ANDREW N | ACRS | Common Stock | D | 4 660 | 9 167 | ||||||
| 2024-06-04 | 2024-06-01 | 4 | Mehra Anand | ACRS | Common Stock | D | 4 660 | 43 364 | ||||||
| 2024-06-04 | 2024-06-01 | 4 | Humphries William D. | ACRS | Common Stock | D | 4 660 | 28 732 | ||||||
| 2024-06-04 | 2024-06-01 | 4 | GOWEN MAXINE | ACRS | Common Stock | D | 4 660 | 16 961 | ||||||
| 2024-06-04 | 2024-06-01 | 4 | Molineaux Christopher P. | ACRS | Common Stock | D | 4 660 | 53 163 | ||||||
| 2024-06-04 | 2024-06-01 | 4 | Reasons Bryan M. | ACRS | Common Stock | D | 4 660 | 28 732 | ||||||
| 2024-06-04 | 2024-06-01 | 4 | MILANO VINCENT | ACRS | Common Stock | D | 4 660 | 12 523 | ||||||
| 2024-06-04 | 2024-06-01 | 4 | Powell Andrew Kenneth William | ACRS | Common Stock | D | 4 660 | 33 523 | ||||||
| 2024-06-04 | 2024-06-01 | 4 | Walker Neal | ACRS | Common Stock | D | 1,0300 | -2 722 | -3 | 1 299 115 | ||||
| 2024-06-04 | 2024-06-01 | 4 | Walker Neal | ACRS | Common Stock | D | 9 466 | 1 301 837 | ||||||
| 2024-05-03 | 2024-05-01 | 4 | Walker Neal | ACRS | Common Stock | D | 1,2600 | -2 784 | -4 | 1 292 371 | ||||
| 2024-05-03 | 2024-05-01 | 4 | Walker Neal | ACRS | Common Stock | D | 9 467 | 1 295 155 | ||||||
| 2024-04-03 | 2024-04-01 | 4 | Walker Neal | ACRS | Common Stock | D | 1,2600 | -3 224 | -4 | 1 285 688 | ||||
| 2024-04-03 | 2024-04-01 | 4 | Walker Neal | ACRS | Common Stock | D | 9 467 | 1 288 912 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Walker Neal | ACRS | Common Stock | D | 1,2400 | -3 223 | -4 | 1 279 445 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Walker Neal | ACRS | Common Stock | D | 9 466 | 1 282 668 | ||||||
| 2024-03-05 | 2024-03-02 | 4 | Monahan Joseph | ACRS | Common Stock | D | 1,2400 | -3 531 | -4 | 186 783 | ||||
| 2024-03-05 | 2024-03-02 | 4 | Monahan Joseph | ACRS | Common Stock | D | 12 500 | 190 314 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 1,2400 | -3 183 | -4 | 177 814 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 10 925 | 180 997 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 1,2400 | -14 569 | -18 | 170 072 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 50 000 | 184 641 | ||||||
| 2024-03-05 | 2024-03-02 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 1,2400 | -427 | -1 | 23 983 | ||||
| 2024-03-05 | 2024-03-02 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 1 500 | 24 410 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 1,2400 | -677 | -1 | 22 910 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 2 375 | 23 587 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 1,2400 | -313 | -0 | 21 212 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 1 100 | 21 525 | ||||||
| 2024-03-05 | 2024-03-04 | 4 | Powell Andrew Kenneth William | ACRS | Common Stock | D | 1,2500 | 6 000 | 8 | 28 863 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Powell Andrew Kenneth William | ACRS | Common Stock | D | 1,2300 | 8 500 | 10 | 22 863 | ||||
| 2024-02-08 | 3 | Leonard Braden Michael Holding of BML Investment Partners, L.P. | ACRS | Common Stock | I | 9 395 934 | ||||||||
| 2024-02-05 | 2024-02-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 1,2000 | -2 583 | -3 | 134 641 | ||||
| 2024-02-05 | 2024-02-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 7 500 | 137 224 | ||||||
| 2024-02-05 | 2024-02-01 | 4 | Loerop James | ACRS | Common Stock | D | 1,2000 | -2 568 | -3 | 34 017 | ||||
| 2024-02-05 | 2024-02-01 | 4 | Loerop James | ACRS | Common Stock | D | 7 500 | 36 585 | ||||||
| 2024-02-05 | 2024-02-01 | 4 | Loerop James | ACRS | Common Stock | D | 1,2000 | -3 853 | -5 | 29 085 | ||||
| 2024-02-05 | 2024-02-01 | 4 | Loerop James | ACRS | Common Stock | D | 11 250 | 32 938 | ||||||
| 2024-01-03 | 2024-01-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 1,0500 | -2 536 | -3 | 20 425 | ||||
| 2024-01-03 | 2024-01-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 7 500 | 22 961 | ||||||
| 2024-01-03 | 2024-01-01 | 4 | Manion Douglas J. | ACRS | Common Stock | D | 1,0500 | -9 125 | -10 | 41 813 | ||||
| 2024-01-03 | 2024-01-01 | 4 | Manion Douglas J. | ACRS | Common Stock | D | 27 000 | 50 938 | ||||||
| 2023-10-25 | 2023-10-23 | 4 | Monahan Joseph | ACRS | Common Stock | D | 5,0767 | -6 000 | -30 | 129 724 | ||||
| 2023-09-07 | 2023-09-06 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 7,9000 | 9 490 | 75 | 15 461 | ||||
| 2023-09-05 | 2023-09-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 7,9000 | -285 | -2 | 5 971 | ||||
| 2023-09-05 | 2023-09-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 1 000 | 6 256 | ||||||
| 2023-08-28 | 2023-08-28 | 4 | Loerop James | ACRS | Common Stock | D | 6,7976 | 14 705 | 100 | 21 688 | ||||
| 2023-08-22 | 2023-08-21 | 4 | Monahan Joseph | ACRS | Common Stock | D | 7,3158 | -6 000 | -44 | 135 724 | ||||
| 2023-08-03 | 2023-08-01 | 4 | Manion Douglas J. | ACRS | Common Stock | D | 9,8100 | -4 437 | -44 | 23 938 | ||||
| 2023-08-03 | 2023-08-01 | 4 | Manion Douglas J. | ACRS | Common Stock | D | 15 575 | 28 375 | ||||||
| 2023-07-05 | 2023-07-01 | 4 | Cawkwell Gail | ACRS | Common Stock | D | 10,3700 | -5 407 | -56 | 9 593 | ||||
| 2023-07-05 | 2023-07-01 | 4 | Cawkwell Gail | ACRS | Common Stock | D | 15 000 | 15 000 | ||||||
| 2023-06-22 | 2023-06-20 | 4 | Molineaux Christopher P. | ACRS | Common Stock | D | 1,4100 | 16 500 | 23 | 48 503 | ||||
| 2023-06-22 | 2023-06-20 | 4 | Monahan Joseph | ACRS | Common Stock | D | 10,2771 | -6 000 | -62 | 141 724 | ||||
| 2023-06-20 | 2023-06-15 | 4 | Molineaux Christopher P. | ACRS | Common Stock | D | 1,5200 | 198 | 0 | 32 003 | ||||
| 2023-06-20 | 2023-06-15 | 4 | Molineaux Christopher P. | ACRS | Common Stock | D | 0,7200 | 51 | 0 | 31 805 | ||||
| 2023-06-05 | 2023-06-02 | 4 | Humphries William D. | ACRS | Common Stock | D | 4 507 | 24 072 | ||||||
| 2023-06-05 | 2023-06-02 | 4 | MILANO VINCENT | ACRS | Common Stock | D | 4 507 | 7 863 | ||||||
| 2023-06-05 | 2023-06-02 | 4 | GOWEN MAXINE | ACRS | Common Stock | D | 4 507 | 12 301 | ||||||
| 2023-06-05 | 2023-06-02 | 4 | Molineaux Christopher P. | ACRS | Common Stock | D | 4 507 | 31 754 | ||||||
| 2023-06-05 | 2023-06-02 | 4 | Reasons Bryan M. | ACRS | Common Stock | D | 4 507 | 24 072 | ||||||
| 2023-06-05 | 2023-06-02 | 4 | SCHIFF ANDREW N | ACRS | Common Stock | D | 4 507 | 4 507 | ||||||
| 2023-06-05 | 2023-06-02 | 4 | Powell Andrew Kenneth William | ACRS | Common Stock | D | 4 507 | 14 363 | ||||||
| 2023-06-05 | 2023-06-02 | 4 | Mehra Anand | ACRS | Common Stock | D | 4 507 | 38 704 | ||||||
| 2023-03-17 | 2023-03-17 | 4 | Manion Douglas J. | ACRS | Common Stock | D | 7,8623 | 6 300 | 50 | 12 800 | ||||
| 2023-03-09 | 2023-03-09 | 4 | Manion Douglas J. | ACRS | Common Stock | D | 7,7350 | 6 500 | 50 | 6 500 | ||||
| 2023-03-03 | 2023-03-03 | 4 | Walker Neal | ACRS | Common Stock | D | 12,6346 | -30 240 | -382 | 1 273 202 | ||||
| 2023-03-03 | 2023-03-02 | 4 | Walker Neal | ACRS | Common Stock | D | 18 254 | 1 303 442 | ||||||
| 2023-03-03 | 2023-03-02 | 4 | Walker Neal | ACRS | Common Stock | D | 12,3651 | -29 000 | -359 | 1 285 188 | ||||
| 2023-03-03 | 2023-03-01 | 4 | Walker Neal | ACRS | Common Stock | D | 24 000 | 1 314 188 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Walker Neal | ACRS | Common Stock | D | 18 275 | 1 290 188 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Walker Neal | ACRS | Common Stock | D | 96 150 | 1 271 913 | ||||||
| 2023-03-03 | 2023-03-03 | 4 | Monahan Joseph | ACRS | Common Stock | D | 12,6342 | -16 037 | -203 | 147 724 | ||||
| 2023-03-03 | 2023-03-02 | 4 | Monahan Joseph | ACRS | Common Stock | D | 12 500 | 163 761 | ||||||
| 2023-03-03 | 2023-03-02 | 4 | Monahan Joseph | ACRS | Common Stock | D | 12,3665 | -14 800 | -183 | 151 261 | ||||
| 2023-03-03 | 2023-03-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 10 925 | 166 061 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 50 000 | 155 136 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 13 750 | 105 136 | ||||||
| 2023-03-03 | 2023-03-03 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 12,6281 | -894 | -11 | 5 256 | ||||
| 2023-03-03 | 2023-03-02 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 1 500 | 6 150 | ||||||
| 2023-03-03 | 2023-03-02 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 12,2890 | -1 000 | -12 | 4 650 | ||||
| 2023-03-03 | 2023-03-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 2 375 | 5 650 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 1 100 | 3 275 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Balthaser Kevin | ACRS | Common Stock | D | 1 475 | 2 175 | ||||||
| 2023-02-17 | 2023-02-15 | 4 | Monahan Joseph | ACRS | Common Stock | D | 13,0621 | -5 000 | -65 | 91 386 | ||||
| 2023-02-10 | 2023-02-08 | 4 | Loerop James | ACRS | Common Stock | D | 13,8909 | -4 267 | -59 | 6 983 | ||||
| 2023-02-03 | 2023-02-02 | 4 | Walker Neal | ACRS | Common Stock | D | 17,5350 | -200 | -4 | 1 175 763 | ||||
| 2023-02-03 | 2023-02-02 | 4 | Walker Neal | ACRS | Common Stock | D | 16,8827 | -3 121 | -53 | 1 175 963 | ||||
| 2023-02-03 | 2023-02-02 | 4 | Walker Neal | ACRS | Common Stock | D | 15,5533 | -600 | -9 | 1 179 084 | ||||
| 2023-02-03 | 2023-02-02 | 4 | Walker Neal | ACRS | Common Stock | D | 14,5671 | -1 079 | -16 | 1 179 684 | ||||
| 2023-02-03 | 2023-02-01 | 4 | Walker Neal | ACRS | Common Stock | D | 16,7470 | -25 000 | -419 | 1 180 763 | ||||
| 2023-02-03 | 2023-02-01 | 4 | Loerop James | ACRS | Common Stock | D | 11 250 | 11 250 | ||||||
| 2023-01-20 | 2022-11-08 | 4 | Powell Andrew Kenneth William | ACRS | Common Stock | D | -4 000 | 9 856 | ||||||
| 2023-01-06 | 3 | Balthaser Kevin | ACRS | Common Stock | D | 700 | ||||||||
| 2023-01-04 | 2023-01-04 | 4 | Walker Neal | ACRS | Common Stock | D | 14,8895 | -15 000 | -223 | 1 205 763 | ||||
| 2023-01-04 | 2023-01-03 | 4 | Walker Neal | ACRS | Common Stock | D | 16,1594 | -1 618 | -26 | 1 220 763 | ||||
| 2023-01-04 | 2023-01-03 | 4 | Walker Neal | ACRS | Common Stock | D | 15,1855 | -23 382 | -355 | 1 222 381 | ||||
| 2022-12-16 | 2022-12-15 | 4 | Monahan Joseph | ACRS | Common Stock | D | 15,8823 | -5 000 | -79 | 96 386 | ||||
| 2022-11-14 | 2022-11-14 | 4 | SCHIFF ANDREW N By Aisling Capital IV LP | ACRS | Common Stock | I | 17,0800 | -1 371 | -23 | 434 455 | ||||
| 2022-11-14 | 2022-11-11 | 4 | SCHIFF ANDREW N By Aisling Capital IV LP | ACRS | Common Stock | I | 17,0597 | -41 160 | -702 | 435 826 | ||||
| 2022-11-14 | 2022-11-10 | 4 | SCHIFF ANDREW N By Aisling Capital IV LP | ACRS | Common Stock | I | 17,0246 | -11 395 | -194 | 476 986 | ||||
| 2022-10-26 | 2022-10-26 | 4 | SCHIFF ANDREW N By Aisling Capital IV LP | ACRS | Common Stock | I | 17,0050 | -14 540 | -247 | 488 381 | ||||
| 2022-10-26 | 2022-10-25 | 4 | SCHIFF ANDREW N By Aisling Capital IV LP | ACRS | Common Stock | I | 17,0175 | -12 018 | -205 | 502 921 | ||||
| 2022-10-26 | 2022-10-24 | 4 | SCHIFF ANDREW N By Aisling Capital IV LP | ACRS | Common Stock | I | 17,0078 | -14 616 | -249 | 514 939 | ||||
| 2022-10-19 | 2022-10-18 | 4 | SCHIFF ANDREW N By Aisling Capital IV LP | ACRS | Common Stock | I | 16,8891 | -32 093 | -542 | 529 555 | ||||
| 2022-10-19 | 2022-10-17 | 4 | SCHIFF ANDREW N By Aisling Capital IV LP | ACRS | Common Stock | I | 16,0493 | -19 944 | -320 | 561 648 | ||||
| 2022-10-19 | 2022-10-17 | 4 | Monahan Joseph | ACRS | Common Stock | D | 15,9815 | -5 000 | -80 | 101 386 | ||||
| 2022-10-11 | 2022-10-07 | 4 | SCHIFF ANDREW N By Aisling Capital IV LP | ACRS | Common Stock | I | 16,1591 | -7 324 | -118 | 581 592 | ||||
| 2022-10-06 | 2022-10-06 | 4 | SCHIFF ANDREW N By Aisling Capital IV LP | ACRS | Common Stock | I | 16,5370 | -37 839 | -626 | 588 916 | ||||
| 2022-10-06 | 2022-10-04 | 4 | SCHIFF ANDREW N By Aisling Capital IV LP | ACRS | Common Stock | I | 16,0076 | -7 700 | -123 | 626 755 | ||||
| 2022-06-21 | 2022-06-17 | 4 | SCHIFF ANDREW N | ACRS | Common Stock | D | 15,1428 | -19 565 | -296 | 0 | ||||
| 2022-06-06 | 2022-06-03 | 4 | SCHIFF ANDREW N | ACRS | Common Stock | D | 3 356 | 19 565 | ||||||
| 2022-06-06 | 2022-06-03 | 4 | Reasons Bryan M. | ACRS | Common Stock | D | 3 356 | 19 565 | ||||||
| 2022-06-06 | 2022-06-03 | 4 | Powell Andrew Kenneth William | ACRS | Common Stock | D | 3 356 | 13 856 | ||||||
| 2022-06-06 | 2022-05-16 | 4 | Powell Andrew Kenneth William | ACRS | Common Stock | D | -709 | 10 500 | ||||||
| 2022-06-06 | 2022-06-03 | 4 | Molineaux Christopher P. | ACRS | Common Stock | D | 3 356 | 27 247 | ||||||
| 2022-06-06 | 2022-06-03 | 4 | MILANO VINCENT | ACRS | Common Stock | D | 3 356 | 3 356 | ||||||
| 2022-06-06 | 2022-06-03 | 4 | Mehra Anand | ACRS | Common Stock | D | 3 356 | 34 197 | ||||||
| 2022-06-06 | 2022-06-03 | 4 | Humphries William D. | ACRS | Common Stock | D | 3 356 | 19 565 | ||||||
| 2022-06-06 | 2022-06-03 | 4 | GOWEN MAXINE | ACRS | Common Stock | D | 3 356 | 7 794 | ||||||
| 2022-04-25 | 2022-04-25 | 4 | Walker Neal | ACRS | Common Stock | D | 15,1828 | -20 000 | -304 | 1 245 763 | ||||
| 2022-04-25 | 2022-04-22 | 4 | Walker Neal | ACRS | Common Stock | D | 15,0439 | -25 000 | -376 | 1 265 763 | ||||
| 2022-04-25 | 2022-04-21 | 4 | Walker Neal | ACRS | Common Stock | D | 15,2379 | -25 000 | -381 | 1 290 763 | ||||
| 2022-04-20 | 2022-04-18 | 4 | Monahan Joseph | ACRS | Common Stock | D | 16,2766 | -30 000 | -488 | 106 386 | ||||
| 2022-03-14 | 2022-03-11 | 4 | Walker Neal | ACRS | Common Stock | D | 15,9147 | -56 303 | -896 | 1 315 763 | ||||
| 2022-03-14 | 2022-03-10 | 4 | Ruffo Frank | ACRS | Common Stock | D | 15,5451 | -12 823 | -199 | 201 883 | ||||
| 2022-03-14 | 2022-03-10 | 4 | Monahan Joseph | ACRS | Common Stock | D | 15,7115 | -27 165 | -427 | 136 386 | ||||
| 2022-03-03 | 2022-03-02 | 4 | Monahan Joseph | ACRS | Restricted stock units | D | -12 500 | 25 000 | ||||||
| 2022-03-03 | 2022-03-02 | 4 | Monahan Joseph | ACRS | Common Stock | D | 12 500 | 163 551 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Monahan Joseph | ACRS | Restricted stock units | D | -50 000 | 150 000 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Monahan Joseph | ACRS | Restricted stock units | D | -13 750 | 13 750 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Monahan Joseph | ACRS | Restricted stock units | D | 43 700 | 43 700 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Monahan Joseph | ACRS | Employee Stock Option (Right to Buy) | D | 14,94 | 153 100 | 153 100 | |||||
| 2022-03-03 | 2022-03-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 50 000 | 151 051 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 13 750 | 101 051 | ||||||
| 2022-03-03 | 2022-03-02 | 4 | Ruffo Frank | ACRS | Restricted stock units | D | -8 297 | 16 595 | ||||||
| 2022-03-03 | 2022-03-02 | 4 | Ruffo Frank | ACRS | Common Stock | D | 8 297 | 214 706 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Ruffo Frank | ACRS | Restricted stock units | D | -8 300 | 24 900 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Ruffo Frank | ACRS | Restricted stock units | D | -25 750 | 25 750 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Ruffo Frank | ACRS | Restricted stock units | D | 44 300 | 44 300 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Ruffo Frank | ACRS | Employee Stock Option (Right to Buy) | D | 14,94 | 155 200 | 155 200 | |||||
| 2022-03-03 | 2022-03-01 | 4 | Ruffo Frank | ACRS | Common Stock | D | 8 300 | 206 409 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Ruffo Frank | ACRS | Common Stock | D | 25 750 | 198 109 | ||||||
| 2022-03-03 | 2022-03-02 | 4 | Walker Neal | ACRS | Restricted stock units | D | -18 254 | 36 508 | ||||||
| 2022-03-03 | 2022-03-02 | 4 | Walker Neal | ACRS | Common Stock | D | 18 254 | 1 372 066 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Walker Neal | ACRS | Restricted stock units | D | -18 275 | 54 825 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Walker Neal | ACRS | Restricted stock units | D | -96 150 | 96 150 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Walker Neal | ACRS | Restricted stock units | D | 96 000 | 96 000 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Walker Neal | ACRS | Employee Stock Option (Right to Buy) | D | 14,94 | 336 100 | 336 100 | |||||
| 2022-03-03 | 2022-03-01 | 4 | Walker Neal | ACRS | Common Stock | D | 18 275 | 1 353 812 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Walker Neal | ACRS | Common Stock | D | 96 150 | 1 335 537 | ||||||
| 2022-02-11 | 2022-02-09 | 4 | Walker Neal | ACRS | Common Stock | D | 12,6602 | -3 595 | -46 | 1 239 387 | ||||
| 2022-02-11 | 2022-02-09 | 4 | Ruffo Frank | ACRS | Common Stock | D | 12,6574 | -1 388 | -18 | 172 359 | ||||
| 2022-02-11 | 2022-02-09 | 4 | Monahan Joseph | ACRS | Common Stock | D | 12,6818 | -383 | -5 | 87 301 | ||||
| 2022-02-03 | 2022-02-01 | 4 | Monahan Joseph | ACRS | Restricted Stock Units | D | -1 050 | 0 | ||||||
| 2022-02-03 | 2022-02-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 1 050 | 87 684 | ||||||
| 2022-02-03 | 2022-02-01 | 4 | Ruffo Frank | ACRS | Restricted Stock Units | D | -3 875 | 0 | ||||||
| 2022-02-03 | 2022-02-01 | 4 | Ruffo Frank | ACRS | Common Stock | D | 3 875 | 173 747 | ||||||
| 2022-02-03 | 2022-02-01 | 4 | Walker Neal | ACRS | Restricted Stock Units | D | -10 800 | 0 | ||||||
| 2022-02-03 | 2022-02-01 | 4 | Walker Neal | ACRS | Common Stock | D | 10 800 | 1 242 982 | ||||||
| 2022-02-01 | 2022-02-01 | 4 | Loerop James | ACRS | Restricted Stock Units | D | 45 000 | 45 000 | ||||||
| 2022-02-01 | 2022-02-01 | 4 | Loerop James | ACRS | Employee Stock Option (Right to Buy) | D | 11,58 | 155 000 | 155 000 | |||||
| 2022-01-05 | 2022-01-03 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Units | D | -7 100 | 0 | ||||||
| 2022-01-05 | 2022-01-03 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Unit | D | -6 638 | 0 | ||||||
| 2022-01-05 | 2022-01-03 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Units | D | -27 905 | 0 | ||||||
| 2022-01-05 | 2022-01-03 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Units | D | -3 875 | 0 | ||||||
| 2022-01-05 | 2022-01-03 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 7 100 | 160 214 | ||||||
| 2022-01-05 | 2022-01-03 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 6 638 | 153 114 | ||||||
| 2022-01-05 | 2022-01-03 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 27 905 | 146 476 | ||||||
| 2022-01-05 | 2022-01-03 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 3 875 | 118 571 | ||||||
| 2021-12-03 | 2021-11-23 | 4 | Powell Andrew Kenneth William | ACRS | Common Stock | D | -5 500 | 11 209 | ||||||
| 2021-11-22 | 2021-03-11 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | -7 500 | 114 696 | ||||||
| 2021-11-03 | 2021-11-01 | 4 | Foresite Capital Management III, LLC | ACRS | Common Stock | I | 8 276 | 8 276 | ||||||
| 2021-11-03 | 2021-11-01 | 4 | Foresite Capital Management III, LLC | ACRS | Common Stock | I | -1 954 904 | 0 | ||||||
| 2021-09-02 | 2021-09-01 | 4 | Monahan Joseph | ACRS | Restricted Stock Units | D | -2 333 | 0 | ||||||
| 2021-09-02 | 2021-09-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 17,2200 | -1 041 | -18 | 86 634 | ||||
| 2021-09-02 | 2021-09-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 2 333 | 87 675 | ||||||
| 2021-07-14 | 2021-07-13 | 4 | Gordon David N. | ACRS | Common Stock | D | 16,9801 | -2 631 | -45 | 147 447 | ||||
| 2021-07-07 | 2021-07-02 | 4 | Gordon David N. | ACRS | Restricted Stock Units | D | -6 000 | 6 000 | ||||||
| 2021-07-07 | 2021-07-02 | 4 | Gordon David N. | ACRS | Common Stock | D | 6 000 | 150 078 | ||||||
| 2021-06-04 | 2021-06-03 | 4 | SCHIFF ANDREW N | ACRS | Restricted Stock Units | D | 3 356 | 3 356 | ||||||
| 2021-06-04 | 2021-06-03 | 4 | SCHIFF ANDREW N | ACRS | Stock Option (Right to Buy) | D | 21,90 | 12 250 | 12 250 | |||||
| 2021-06-04 | 2021-06-03 | 4 | Reasons Bryan M. | ACRS | Restricted Stock Units | D | 3 356 | 3 356 | ||||||
| 2021-06-04 | 2021-06-03 | 4 | Reasons Bryan M. | ACRS | Stock Option (Right to Buy) | D | 21,90 | 12 250 | 12 250 | |||||
| 2021-06-04 | 2021-06-03 | 4 | Powell Andrew Kenneth William | ACRS | Restricted Stock Units | D | 3 356 | 3 356 | ||||||
| 2021-06-04 | 2021-06-03 | 4 | Powell Andrew Kenneth William | ACRS | Stock Option (Right to Buy) | D | 21,90 | 12 250 | 12 250 | |||||
| 2021-06-04 | 2021-06-03 | 4 | Molineaux Christopher P. | ACRS | Restricted Stock Units | D | 3 356 | 3 356 | ||||||
| 2021-06-04 | 2021-06-03 | 4 | Molineaux Christopher P. | ACRS | Stock Option (Right to Buy) | D | 21,90 | 12 250 | 12 250 | |||||
| 2021-06-04 | 2021-06-03 | 4 | MILANO VINCENT | ACRS | Restricted Stock Units | D | 3 356 | 3 356 | ||||||
| 2021-06-04 | 2021-06-03 | 4 | MILANO VINCENT | ACRS | Stock Option (Right to Buy) | D | 21,90 | 12 250 | 12 250 | |||||
| 2021-06-04 | 2021-06-03 | 4 | Mehra Anand | ACRS | Restricted Stock Units | D | 3 356 | 3 356 | ||||||
| 2021-06-04 | 2021-06-03 | 4 | Mehra Anand | ACRS | Stock Option (Right to Buy) | D | 21,90 | 12 250 | 12 250 | |||||
| 2021-06-04 | 2021-06-03 | 4 | Humphries William D. | ACRS | Restricted Stock Units | D | 3 356 | 3 356 | ||||||
| 2021-06-04 | 2021-06-03 | 4 | Humphries William D. | ACRS | Stock Option (Right to Buy) | D | 21,90 | 12 250 | 12 250 | |||||
| 2021-06-04 | 2021-06-03 | 4 | GOWEN MAXINE | ACRS | Restricted Stock Units | D | 3 356 | 3 356 | ||||||
| 2021-06-04 | 2021-06-03 | 4 | GOWEN MAXINE | ACRS | Stock Option (Right to Buy) | D | 21,90 | 12 250 | 12 250 | |||||
| 2021-06-04 | 2021-06-03 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 21,9575 | -9 492 | -208 | 122 196 | ||||
| 2021-06-02 | 2021-06-02 | 4 | Gordon David N. | ACRS | Common Stock | D | 22,2649 | -6 800 | -151 | 144 078 | ||||
| 2021-06-02 | 2021-06-02 | 4 | Gordon David N. | ACRS | Common Stock | D | 21,4954 | -31 114 | -669 | 150 878 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Gordon David N. | ACRS | Restricted Stock Units | D | -87 500 | 0 | ||||||
| 2021-06-02 | 2021-06-01 | 4 | Gordon David N. | ACRS | Common Stock | D | 23,5705 | -4 885 | -115 | 181 992 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Gordon David N. | ACRS | Common Stock | D | 22,7124 | -9 115 | -207 | 186 877 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Gordon David N. | ACRS | Common Stock | D | 87 500 | 195 992 | ||||||
| 2021-06-02 | 2021-06-02 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 22,3112 | -2 387 | -53 | 131 688 | ||||
| 2021-06-02 | 2021-06-02 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 21,5066 | -12 732 | -274 | 134 075 | ||||
| 2021-06-02 | 2021-06-02 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 22,3175 | -2 517 | -56 | 146 807 | ||||
| 2021-06-02 | 2021-06-02 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 21,5022 | -12 483 | -268 | 149 324 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Units | D | -33 189 | 0 | ||||||
| 2021-06-02 | 2021-06-01 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 23,5728 | -5 254 | -124 | 161 807 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 22,7219 | -9 746 | -221 | 167 061 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 33 189 | 176 807 | ||||||
| 2021-06-02 | 2021-06-02 | 4 | Monahan Joseph | ACRS | Common Stock | D | 22,3114 | -3 550 | -79 | 85 342 | ||||
| 2021-06-02 | 2021-06-02 | 4 | Monahan Joseph | ACRS | Common Stock | D | 21,5039 | -18 240 | -392 | 88 892 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Monahan Joseph | ACRS | Restricted Stock Units | D | -50 000 | 0 | ||||||
| 2021-06-02 | 2021-06-01 | 4 | Monahan Joseph | ACRS | Common Stock | D | 50 000 | 107 132 | ||||||
| 2021-06-02 | 2021-06-02 | 4 | Walker Neal | ACRS | Common Stock | D | 22,3017 | -5 517 | -123 | 1 232 182 | ||||
| 2021-06-02 | 2021-06-02 | 4 | Walker Neal | ACRS | Common Stock | D | 21,5080 | -27 743 | -597 | 1 237 699 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Walker Neal | ACRS | Restricted Stock Units | D | -73 015 | 0 | ||||||
| 2021-06-02 | 2021-06-01 | 4 | Walker Neal | ACRS | Common Stock | D | 73 015 | 1 265 442 | ||||||
| 2021-06-02 | 2021-06-02 | 4 | Ruffo Frank | ACRS | Common Stock | D | 22,3000 | -2 450 | -55 | 169 872 | ||||
| 2021-06-02 | 2021-06-02 | 4 | Ruffo Frank | ACRS | Common Stock | D | 21,5101 | -12 587 | -271 | 172 322 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Ruffo Frank | ACRS | Restricted Stock Units | D | -33 189 | 0 | ||||||
| 2021-06-02 | 2021-06-01 | 4 | Ruffo Frank | ACRS | Common Stock | D | 33 189 | 184 909 | ||||||
| 2021-05-17 | 3 | Monahan Joseph | ACRS | Common Stock | D | 57 132 | ||||||||
| 2021-05-17 | 3 | Monahan Joseph By Spouse | ACRS | Common Stock | I | 193 | ||||||||
| 2021-05-07 | 2021-05-07 | 4 | Ali-Jackson Kamil | ACRS | Employee Stock Option (Right to Buy) | D | 10,66 | -5 416 | 0 | |||||
| 2021-05-07 | 2021-05-07 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 23,9886 | -2 100 | -50 | 143 618 | ||||
| 2021-05-07 | 2021-05-07 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 23,2255 | -3 316 | -77 | 145 718 | ||||
| 2021-05-07 | 2021-05-07 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 10,6600 | 5 416 | 58 | 149 034 | ||||
| 2021-05-07 | 2021-05-06 | 4 | Ali-Jackson Kamil | ACRS | Employee Stock Option (Right to Buy) | D | 10,66 | -15 000 | 5 416 | |||||
| 2021-05-07 | 2021-05-06 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 23,8606 | -3 102 | -74 | 143 618 | ||||
| 2021-05-07 | 2021-05-06 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 23,3180 | -11 898 | -277 | 146 720 | ||||
| 2021-05-07 | 2021-05-06 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 10,6600 | 15 000 | 160 | 158 618 | ||||
| 2021-05-05 | 2021-05-05 | 4 | Ali-Jackson Kamil | ACRS | Employee Stock Option (Right to Buy) | D | 10,66 | -15 000 | 20 416 | |||||
| 2021-05-05 | 2021-05-05 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 24,3559 | -498 | -12 | 143 618 | ||||
| 2021-05-05 | 2021-05-05 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 23,9680 | -14 502 | -348 | 144 116 | ||||
| 2021-05-05 | 2021-05-05 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 10,6600 | 15 000 | 160 | 158 618 | ||||
| 2021-05-05 | 2021-05-04 | 4 | Ali-Jackson Kamil | ACRS | Employee Stock Option (Right to Buy) | D | 10,66 | -15 000 | 35 416 | |||||
| 2021-05-05 | 2021-05-04 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 24,4691 | -1 279 | -31 | 143 618 | ||||
| 2021-05-05 | 2021-05-04 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 23,6055 | -13 721 | -324 | 144 897 | ||||
| 2021-05-05 | 2021-05-04 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 10,6600 | 15 000 | 160 | 158 618 | ||||
| 2021-05-05 | 2021-05-03 | 4 | Ali-Jackson Kamil | ACRS | Employee Stock Option (Right to Buy) | D | 10,66 | -15 000 | 50 416 | |||||
| 2021-05-05 | 2021-05-03 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 24,9075 | -4 339 | -108 | 143 618 | ||||
| 2021-05-05 | 2021-05-03 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 24,4578 | -10 661 | -261 | 147 957 | ||||
| 2021-05-05 | 2021-05-03 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 10,6600 | 15 000 | 160 | 158 618 | ||||
| 2021-04-26 | 2021-04-26 | 4 | Ruffo Frank | ACRS | Common Stock | D | 26,4400 | -100 | -3 | 151 720 | ||||
| 2021-04-26 | 2021-04-26 | 4 | Ruffo Frank | ACRS | Common Stock | D | 25,7933 | -27 239 | -703 | 151 820 | ||||
| 2021-04-26 | 2021-04-23 | 4 | Ruffo Frank | ACRS | Common Stock | D | 27,3287 | -800 | -22 | 179 059 | ||||
| 2021-04-26 | 2021-04-23 | 4 | Ruffo Frank | ACRS | Common Stock | D | 26,6369 | -29 200 | -778 | 179 859 | ||||
| 2021-04-26 | 2021-04-22 | 4 | Ruffo Frank | ACRS | Common Stock | D | 26,8406 | -30 000 | -805 | 209 059 | ||||
| 2021-04-26 | 2021-04-22 | 4 | Walker Neal | ACRS | Common Stock | D | 26,8413 | -30 000 | -805 | 1 192 427 | ||||
| 2021-03-03 | 2021-03-02 | 4 | Gordon David N. | ACRS | Restricted stock units | D | -8 297 | 24 892 | ||||||
| 2021-03-03 | 2021-03-02 | 4 | Gordon David N. | ACRS | Common Stock | D | 23,2500 | -2 280 | -53 | 108 492 | ||||
| 2021-03-03 | 2021-03-02 | 4 | Gordon David N. | ACRS | Common Stock | D | 8 297 | 110 772 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Gordon David N. | ACRS | Restricted stock units | D | -20 600 | 41 200 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Gordon David N. | ACRS | Restricted stock units | D | 28 400 | 28 400 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Gordon David N. | ACRS | Employee Stock Option (Right to Buy) | D | 24,06 | 99 500 | 99 500 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Gordon David N. | ACRS | Common Stock | D | 24,0600 | -5 660 | -136 | 102 475 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Gordon David N. | ACRS | Common Stock | D | 20 600 | 108 135 | ||||||
| 2021-03-03 | 2021-03-02 | 4 | Ali-Jackson Kamil | ACRS | Restricted stock units | D | -6 637 | 19 914 | ||||||
| 2021-03-03 | 2021-03-02 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 23,2500 | -1 906 | -44 | 143 618 | ||||
| 2021-03-03 | 2021-03-02 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 6 637 | 145 524 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Ali-Jackson Kamil | ACRS | Restricted stock units | D | -17 175 | 34 350 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Ali-Jackson Kamil | ACRS | Restricted stock units | D | 28 400 | 28 400 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Ali-Jackson Kamil | ACRS | Employee Stock Option (Right to Buy) | D | 24,06 | 99 500 | 99 500 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 24,0600 | -4 934 | -119 | 138 887 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 17 175 | 143 821 | ||||||
| 2021-03-03 | 2021-03-02 | 4 | Ruffo Frank | ACRS | Restricted stock units | D | -8 297 | 24 892 | ||||||
| 2021-03-03 | 2021-03-02 | 4 | Ruffo Frank | ACRS | Common Stock | D | 23,2500 | -2 844 | -66 | 239 059 | ||||
| 2021-03-03 | 2021-03-02 | 4 | Ruffo Frank | ACRS | Common Stock | D | 8 297 | 241 903 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Ruffo Frank | ACRS | Restricted stock units | D | -25 750 | 51 500 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Ruffo Frank | ACRS | Restricted stock units | D | 33 200 | 33 200 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Ruffo Frank | ACRS | Employee Stock Option (Right to Buy) | D | 24,06 | 116 000 | 116 000 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Ruffo Frank | ACRS | Common Stock | D | 24,0600 | -7 333 | -176 | 233 606 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Ruffo Frank | ACRS | Common Stock | D | 25 750 | 240 939 | ||||||
| 2021-03-03 | 2021-03-02 | 4 | Walker Neal | ACRS | Restricted stock units | D | -18 253 | 54 762 | ||||||
| 2021-03-03 | 2021-03-02 | 4 | Walker Neal | ACRS | Common Stock | D | 23,2500 | -7 982 | -186 | 1 222 427 | ||||
| 2021-03-03 | 2021-03-02 | 4 | Walker Neal | ACRS | Common Stock | D | 18 253 | 1 230 409 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Walker Neal | ACRS | Restricted stock units | D | -96 150 | 192 300 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Walker Neal | ACRS | Restricted stock units | D | 73 100 | 73 100 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Walker Neal | ACRS | Employee Stock Option (Right to Buy) | D | 24,06 | 255 800 | 255 800 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Walker Neal | ACRS | Common Stock | D | 24,0600 | -39 792 | -957 | 1 212 156 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Walker Neal | ACRS | Common Stock | D | 96 150 | 1 251 948 | ||||||
| 2021-02-10 | 3 | Tananbaum James B. | ACRS | Common Stock | I | 3 399 034 | ||||||||
| 2021-02-10 | 3 | Tananbaum James B. | ACRS | Common Stock | I | 1 258 243 | ||||||||
| 2021-02-10 | 3 | Tananbaum James B. | ACRS | Common Stock | I | 1 954 904 | ||||||||
| 2021-02-03 | 2021-02-02 | 4 | Mehra Anand | ACRS | Option Grant (right to buy) | D | 18,32 | -6 632 | 0 | |||||
| 2021-02-03 | 2021-02-02 | 4 | Mehra Anand | ACRS | Option Grant (right to buy) | D | 18,35 | -8 000 | 0 | |||||
| 2021-02-03 | 2021-02-02 | 4 | Mehra Anand | ACRS | Common Stock | D | 18,3200 | 6 632 | 121 | 30 841 | ||||
| 2021-02-03 | 2021-02-02 | 4 | Mehra Anand | ACRS | Common Stock | D | 18,3500 | 8 000 | 147 | 24 209 | ||||
| 2021-02-03 | 2021-02-01 | 4 | Ruffo Frank | ACRS | Restricted Stock Units | D | -3 875 | 3 875 | ||||||
| 2021-02-03 | 2021-02-01 | 4 | Ruffo Frank | ACRS | Common Stock | D | 21,3500 | -1 308 | -28 | 215 189 | ||||
| 2021-02-03 | 2021-02-01 | 4 | Ruffo Frank | ACRS | Common Stock | D | 3 875 | 216 497 | ||||||
| 2021-02-03 | 2021-02-01 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Units | D | -3 875 | 3 875 | ||||||
| 2021-02-03 | 2021-02-01 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 21,3500 | -1 318 | -28 | 126 646 | ||||
| 2021-02-03 | 2021-02-01 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 3 875 | 127 964 | ||||||
| 2021-02-03 | 2021-02-01 | 4 | Walker Neal | ACRS | Restricted Stock Units | D | -10 800 | 10 800 | ||||||
| 2021-02-03 | 2021-02-01 | 4 | Walker Neal | ACRS | Common Stock | D | 21,3500 | -3 316 | -71 | 1 155 798 | ||||
| 2021-02-03 | 2021-02-01 | 4 | Walker Neal | ACRS | Common Stock | D | 10 800 | 1 159 114 | ||||||
| 2020-12-17 | 2020-12-15 | 4 | Walker Neal | ACRS | Restricted Stock Units | D | -3 034 | 0 | ||||||
| 2020-12-17 | 2020-12-15 | 4 | Walker Neal | ACRS | Common Stock | D | 4,5900 | -871 | -4 | 1 148 314 | ||||
| 2020-12-17 | 2020-12-15 | 4 | Walker Neal | ACRS | Common Stock | D | 3 034 | 1 149 185 | ||||||
| 2020-12-17 | 2020-12-15 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Units | D | -1 734 | 0 | ||||||
| 2020-12-17 | 2020-12-15 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 4,5900 | -498 | -2 | 124 089 | ||||
| 2020-12-17 | 2020-12-15 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 1 734 | 124 587 | ||||||
| 2020-12-17 | 2020-12-15 | 4 | Ruffo Frank | ACRS | Restricted Stock Units | D | -1 300 | 0 | ||||||
| 2020-12-17 | 2020-12-15 | 4 | Ruffo Frank | ACRS | Common Stock | D | 4,5900 | -370 | -2 | 212 622 | ||||
| 2020-12-17 | 2020-12-15 | 4 | Ruffo Frank | ACRS | Common Stock | D | 1 300 | 212 992 | ||||||
| 2020-09-03 | 2020-09-01 | 4 | Walker Neal | ACRS | Restricted stock units | D | -83 092 | 0 | ||||||
| 2020-09-03 | 2020-09-01 | 4 | Walker Neal | ACRS | Restricted stock units | D | 83 092 | 83 092 | ||||||
| 2020-09-03 | 2020-09-01 | 4 | Walker Neal | ACRS | Common Stock | D | 2,3300 | -23 872 | -56 | 1 146 151 | ||||
| 2020-09-03 | 2020-09-01 | 4 | Walker Neal | ACRS | Common Stock | D | 83 092 | 1 170 023 | ||||||
| 2020-07-07 | 2020-07-02 | 4 | Gordon David N. | ACRS | Restricted stock units | D | -6 000 | 12 000 | ||||||
| 2020-07-07 | 2020-07-02 | 4 | Gordon David N. | ACRS | Common Stock | D | 1,5000 | -1 360 | -2 | 87 535 | ||||
| 2020-07-07 | 2020-07-02 | 4 | Gordon David N. | ACRS | Common Stock | D | 6 000 | 88 895 | ||||||
| 2020-06-08 | 2020-06-06 | 4 | Mehra Anand | ACRS | Restricted Stock Units | D | -7 333 | 0 | ||||||
| 2020-06-08 | 2020-06-06 | 4 | Mehra Anand | ACRS | Common Stock | D | 7 333 | 16 209 | ||||||
| 2020-06-08 | 2020-06-04 | 4 | Mehra Anand | ACRS | Option Grant (right to buy) | D | 1,41 | 16 500 | 16 500 | |||||
| 2020-06-08 | 2020-06-06 | 4 | Molineaux Christopher P. | ACRS | Restricted Stock Units | D | -7 333 | 0 | ||||||
| 2020-06-08 | 2020-06-06 | 4 | Molineaux Christopher P. | ACRS | Common Stock | D | 7 333 | 23 891 | ||||||
| 2020-06-08 | 2020-06-04 | 4 | Molineaux Christopher P. | ACRS | Option Grant (right to buy) | D | 1,41 | 16 500 | 16 500 | |||||
| 2020-06-08 | 2020-06-04 | 4 | GOWEN MAXINE | ACRS | Option Grant (right to buy) | D | 1,41 | 16 500 | 16 500 | |||||
| 2020-06-08 | 2020-06-06 | 4 | Reasons Bryan M. | ACRS | Restricted Stock Units | D | -7 333 | 0 | ||||||
| 2020-06-08 | 2020-06-06 | 4 | Reasons Bryan M. | ACRS | Common Stock | D | 7 333 | 16 209 | ||||||
| 2020-06-08 | 2020-06-04 | 4 | Reasons Bryan M. | ACRS | Option Grant (right to buy) | D | 1,41 | 16 500 | 16 500 | |||||
| 2020-06-08 | 2020-06-04 | 4 | MILANO VINCENT | ACRS | Option Grant (right to buy) | D | 1,41 | 16 500 | 16 500 | |||||
| 2020-06-08 | 2020-06-06 | 4 | SCHIFF ANDREW N | ACRS | Restricted Stock Units | D | -7 333 | 0 | ||||||
| 2020-06-08 | 2020-06-06 | 4 | SCHIFF ANDREW N | ACRS | Common Stock | D | 7 333 | 16 209 | ||||||
| 2020-06-08 | 2020-06-04 | 4 | SCHIFF ANDREW N | ACRS | Option Grant (right to buy) | D | 1,41 | 16 500 | 16 500 | |||||
| 2020-06-08 | 2020-06-06 | 4 | Powell Andrew Kenneth William | ACRS | Restricted Stock Units | D | -7 333 | 0 | ||||||
| 2020-06-08 | 2020-06-06 | 4 | Powell Andrew Kenneth William | ACRS | Common Stock | D | 7 333 | 16 709 | ||||||
| 2020-06-08 | 2020-06-04 | 4 | Powell Andrew Kenneth William | ACRS | Option Grant (right to buy) | D | 1,41 | 16 500 | 16 500 | |||||
| 2020-06-08 | 2020-06-06 | 4 | Humphries William D. | ACRS | Restricted Stock Units | D | -7 333 | 0 | ||||||
| 2020-06-08 | 2020-06-06 | 4 | Humphries William D. | ACRS | Common Stock | D | 7 333 | 16 209 | ||||||
| 2020-06-08 | 2020-06-04 | 4 | Humphries William D. | ACRS | Option Grant (right to buy) | D | 1,41 | 16 500 | 16 500 | |||||
| 2020-06-03 | 2020-06-01 | 4 | Walker Neal | ACRS | Restricted stock units | D | -73 014 | 73 015 | ||||||
| 2020-06-03 | 2020-06-01 | 4 | Walker Neal | ACRS | Common Stock | D | 1,3200 | -20 976 | -28 | 1 086 931 | ||||
| 2020-06-03 | 2020-06-01 | 4 | Walker Neal | ACRS | Common Stock | D | 73 014 | 1 107 907 | ||||||
| 2020-06-03 | 2020-06-01 | 4 | Ali-Jackson Kamil | ACRS | Restricted stock units | D | -33 188 | 33 189 | ||||||
| 2020-06-03 | 2020-06-01 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 1,3200 | -9 534 | -13 | 122 853 | ||||
| 2020-06-03 | 2020-06-01 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 33 188 | 132 387 | ||||||
| 2020-06-03 | 2020-06-01 | 4 | Gordon David N. | ACRS | Restricted stock units | D | -87 500 | 87 500 | ||||||
| 2020-06-03 | 2020-06-01 | 4 | Gordon David N. | ACRS | Common Stock | D | 1,3200 | -24 045 | -32 | 82 895 | ||||
| 2020-06-03 | 2020-06-01 | 4 | Gordon David N. | ACRS | Common Stock | D | 87 500 | 106 940 | ||||||
| 2020-06-03 | 2020-06-01 | 4 | Ruffo Frank | ACRS | Restricted stock units | D | -33 188 | 33 189 | ||||||
| 2020-06-03 | 2020-06-01 | 4 | Ruffo Frank | ACRS | Common Stock | D | 1,3200 | -9 451 | -12 | 211 692 | ||||
| 2020-06-03 | 2020-06-01 | 4 | Ruffo Frank | ACRS | Common Stock | D | 33 188 | 221 143 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Ruffo Frank | ACRS | Restricted stock units | D | 33 189 | 33 189 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Ruffo Frank | ACRS | Restricted stock units | D | 66 377 | 66 377 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Ruffo Frank | ACRS | Employee Stock Option (Right to Buy) | D | 1,26 | 116 160 | 116 160 | |||||
| 2020-03-04 | 2020-03-02 | 4 | Ruffo Frank | ACRS | Restricted stock units | D | -25 750 | 77 250 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Ruffo Frank | ACRS | Common Stock | D | 1,2600 | -7 162 | -9 | 187 955 | ||||
| 2020-03-04 | 2020-03-02 | 4 | Ruffo Frank | ACRS | Common Stock | D | 25 750 | 195 117 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Walker Neal | ACRS | Restricted stock units | D | -52 564 | 0 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Walker Neal | ACRS | Restricted stock units | D | 52 564 | 52 564 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Walker Neal | ACRS | Restricted stock units | D | 73 015 | 73 015 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Walker Neal | ACRS | Restricted stock units | D | 146 029 | 146 029 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Walker Neal | ACRS | Employee Stock Option (Right to Buy) | D | 1,26 | 255 552 | 255 552 | |||||
| 2020-03-04 | 2020-03-02 | 4 | Walker Neal | ACRS | Restricted stock units | D | -96 150 | 288 450 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Walker Neal | ACRS | Common Stock | D | 1,2600 | -15 101 | -19 | 1 034 893 | ||||
| 2020-03-04 | 2020-03-02 | 4 | Walker Neal | ACRS | Common Stock | D | 52 564 | 1 049 994 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Walker Neal | ACRS | Common Stock | D | 1,2600 | -27 623 | -35 | 997 430 | ||||
| 2020-03-04 | 2020-03-02 | 4 | Walker Neal | ACRS | Common Stock | D | 96 150 | 1 025 053 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Ali-Jackson Kamil | ACRS | Restricted stock units | D | 26 551 | 26 551 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Ali-Jackson Kamil | ACRS | Restricted stock units | D | 66 377 | 66 377 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Ali-Jackson Kamil | ACRS | Employee Stock Option (Right to Buy) | D | 1,26 | 92 928 | 92 928 | |||||
| 2020-03-04 | 2020-03-02 | 4 | Ali-Jackson Kamil | ACRS | Restricted stock units | D | -17 175 | 51 525 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 1,2600 | -4 779 | -6 | 99 199 | ||||
| 2020-03-04 | 2020-03-02 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 17 175 | 103 978 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | GOWEN MAXINE | ACRS | Restricted stock units | D | -4 438 | 0 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | GOWEN MAXINE | ACRS | Restricted stock units | D | 4 438 | 4 438 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | GOWEN MAXINE | ACRS | Common Stock | D | 4 438 | 4 438 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Humphries William D. | ACRS | Restricted stock units | D | -8 876 | 0 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Humphries William D. | ACRS | Restricted stock units | D | 8 876 | 8 876 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Humphries William D. | ACRS | Common Stock | D | 8 876 | 8 876 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Mehra Anand | ACRS | Restricted stock units | D | -8 876 | 0 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Mehra Anand | ACRS | Restricted stock units | D | 8 876 | 8 876 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Mehra Anand | ACRS | Common Stock | D | 8 876 | 8 876 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Molineaux Christopher P. | ACRS | Restricted stock units | D | -8 876 | 0 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Molineaux Christopher P. | ACRS | Restricted stock units | D | 8 876 | 8 876 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Molineaux Christopher P. | ACRS | Common Stock | D | 8 876 | 16 558 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Powell Andrew Kenneth William | ACRS | Restricted stock units | D | -8 876 | 0 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Powell Andrew Kenneth William | ACRS | Restricted stock units | D | 8 876 | 8 876 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Powell Andrew Kenneth William | ACRS | Common Stock | D | 8 876 | 9 376 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Reasons Bryan M. | ACRS | Restricted stock units | D | -8 876 | 0 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Reasons Bryan M. | ACRS | Restricted stock units | D | 8 876 | 8 876 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Reasons Bryan M. | ACRS | Common Stock | D | 8 876 | 8 876 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | SCHIFF ANDREW N | ACRS | Restricted stock units | D | -8 876 | 0 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | SCHIFF ANDREW N | ACRS | Restricted stock units | D | 8 876 | 8 876 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | SCHIFF ANDREW N | ACRS | Common Stock | D | 8 876 | 8 876 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Gordon David N. | ACRS | Restricted stock units | D | 33 189 | 33 189 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Gordon David N. | ACRS | Employee Stock Option (Right to Buy) | D | 1,26 | 116 160 | 116 160 | |||||
| 2020-03-04 | 2020-03-02 | 4 | Gordon David N. | ACRS | Restricted stock units | D | -20 600 | 61 800 | ||||||
| 2020-03-04 | 2020-03-02 | 4 | Gordon David N. | ACRS | Common Stock | D | 1,2600 | -5 512 | -7 | 19 440 | ||||
| 2020-03-04 | 2020-03-02 | 4 | Gordon David N. | ACRS | Common Stock | D | 20 600 | 24 952 | ||||||
| 2020-02-04 | 2020-02-03 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Units | D | -3 875 | 7 750 | ||||||
| 2020-02-04 | 2020-02-03 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 1,2800 | -1 318 | -2 | 86 803 | ||||
| 2020-02-04 | 2020-02-03 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 3 875 | 88 121 | ||||||
| 2020-02-04 | 2020-02-03 | 4 | Ruffo Frank | ACRS | Restricted Stock Units | D | -3 875 | 7 750 | ||||||
| 2020-02-04 | 2020-02-03 | 4 | Ruffo Frank | ACRS | Common Stock | D | 1,2800 | -1 308 | -2 | 169 367 | ||||
| 2020-02-04 | 2020-02-03 | 4 | Ruffo Frank | ACRS | Common Stock | D | 3 875 | 170 675 | ||||||
| 2020-02-04 | 2020-02-03 | 4 | Walker Neal | ACRS | Restricted Stock Units | D | -10 800 | 21 600 | ||||||
| 2020-02-04 | 2020-02-03 | 4 | Walker Neal | ACRS | Common Stock | D | 1,2800 | -3 675 | -5 | 928 903 | ||||
| 2020-02-04 | 2020-02-03 | 4 | Walker Neal | ACRS | Common Stock | D | 10 800 | 932 578 | ||||||
| 2020-01-09 | 2020-01-07 | 4 | MILANO VINCENT | ACRS | Stock Option (right to buy) | D | 1,85 | 22 000 | 22 000 | |||||
| 2019-12-20 | 2019-12-18 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Units | D | -1 075 | 0 | ||||||
| 2019-12-20 | 2019-12-18 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 1,8100 | -277 | -1 | 84 246 | ||||
| 2019-12-20 | 2019-12-18 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 1 075 | 84 523 | ||||||
| 2019-12-20 | 2019-12-18 | 4 | Ruffo Frank | ACRS | Restricted Stock Units | D | -1 250 | 0 | ||||||
| 2019-12-20 | 2019-12-18 | 4 | Ruffo Frank | ACRS | Common Stock | D | 1,8100 | -356 | -1 | 166 800 | ||||
| 2019-12-20 | 2019-12-18 | 4 | Ruffo Frank | ACRS | Common Stock | D | 1 250 | 167 156 | ||||||
| 2019-12-20 | 2019-12-18 | 4 | Walker Neal | ACRS | Restricted Stock Units | D | -2 925 | 0 | ||||||
| 2019-12-20 | 2019-12-18 | 4 | Walker Neal | ACRS | Common Stock | D | 1,8100 | -743 | -1 | 921 778 | ||||
| 2019-12-20 | 2019-12-18 | 4 | Walker Neal | ACRS | Common Stock | D | 2 925 | 922 521 | ||||||
| 2019-12-18 | 2019-12-16 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Units | D | -1 733 | 1 734 | ||||||
| 2019-12-18 | 2019-12-16 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 1,8000 | -497 | -1 | 83 448 | ||||
| 2019-12-18 | 2019-12-16 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 1 733 | 83 945 | ||||||
| 2019-12-18 | 2019-12-16 | 4 | Ruffo Frank | ACRS | Restricted Stock Units | D | -1 300 | 1 300 | ||||||
| 2019-12-18 | 2019-12-16 | 4 | Ruffo Frank | ACRS | Common Stock | D | 1,8000 | -370 | -1 | 165 906 | ||||
| 2019-12-18 | 2019-12-16 | 4 | Ruffo Frank | ACRS | Common Stock | D | 1 300 | 166 276 | ||||||
| 2019-12-18 | 2019-12-16 | 4 | Walker Neal | ACRS | Restricted Stock Units | D | -3 033 | 3 034 | ||||||
| 2019-12-18 | 2019-12-16 | 4 | Walker Neal | ACRS | Common Stock | D | 1,8000 | -782 | -1 | 919 596 | ||||
| 2019-12-18 | 2019-12-16 | 4 | Walker Neal | ACRS | Common Stock | D | 3 033 | 920 378 | ||||||
| 2019-10-31 | 2019-10-30 | 4 | Gordon David N. | ACRS | Restricted stock units | D | 175 000 | 175 000 | ||||||
| 2019-07-03 | 2019-07-02 | 4 | Gordon David N. | ACRS | Restricted Stock Units | D | -6 000 | 18 000 | ||||||
| 2019-07-03 | 2019-07-02 | 4 | Gordon David N. | ACRS | Common Stock | D | 2,3400 | -1 648 | -4 | 4 352 | ||||
| 2019-07-03 | 2019-07-02 | 4 | Gordon David N. | ACRS | Common Stock | D | 6 000 | 6 000 | ||||||
| 2019-07-03 | 2019-07-02 | 4 | GOWEN MAXINE | ACRS | Stock option (right to buy) | D | 2,34 | 16 000 | 16 000 | |||||
| 2019-07-01 | 2019-06-27 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Common Stock | I | 2,6907 | -590 801 | -1 590 | 3 159 165 | ||||
| 2019-07-01 | 2019-06-27 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | ACRS | Common Stock | I | 2,6907 | -108 674 | -292 | 964 101 | ||||
| 2019-06-26 | 2019-06-26 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Common Stock | I | 4,5015 | -1 352 | -6 | 3 749 966 | ||||
| 2019-06-26 | 2019-06-26 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | ACRS | Common Stock | I | 4,5015 | -352 | -2 | 1 072 775 | ||||
| 2019-06-25 | 2019-06-25 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Common Stock | I | 4,5089 | -40 850 | -184 | 3 751 318 | ||||
| 2019-06-25 | 2019-06-25 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | ACRS | Common Stock | I | 4,5089 | -10 634 | -48 | 1 073 127 | ||||
| 2019-06-25 | 2019-06-24 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Common Stock | I | 4,5225 | -50 177 | -227 | 3 792 168 | ||||
| 2019-06-25 | 2019-06-24 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | ACRS | Common Stock | I | 4,5225 | -13 063 | -59 | 1 083 761 | ||||
| 2019-06-25 | 2019-06-21 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Common Stock | I | 4,6154 | -269 402 | -1 243 | 3 842 345 | ||||
| 2019-06-25 | 2019-06-21 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | ACRS | Common Stock | I | 4,6154 | -70 135 | -324 | 1 096 824 | ||||
| 2019-06-10 | 2019-06-06 | 4 | Mehra Anand | ACRS | Restricted Stock Units | D | 7 333 | 7 333 | ||||||
| 2019-06-10 | 2019-06-06 | 4 | SCHIFF ANDREW N | ACRS | Restricted Stock Units | D | 7 333 | 7 333 | ||||||
| 2019-06-10 | 2019-06-06 | 4 | Reasons Bryan M. | ACRS | Restricted Stock Units | D | 7 333 | 7 333 | ||||||
| 2019-06-10 | 2019-06-06 | 4 | Powell Andrew Kenneth William | ACRS | Restricted Stock Units | D | 7 333 | 7 333 | ||||||
| 2019-06-10 | 2019-06-06 | 4 | Molineaux Christopher P. | ACRS | Restricted Stock Units | D | 7 333 | 7 333 | ||||||
| 2019-06-10 | 2019-06-06 | 4 | Humphries William D. | ACRS | Restricted Stock Units | D | 7 333 | 7 333 | ||||||
| 2019-05-13 | 2019-05-10 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | ACRS | Common Stock | I | 6,0492 | -71 869 | -435 | 1 166 959 | ||||
| 2019-05-13 | 2019-05-10 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Common Stock | I | 6,0492 | -108 696 | -658 | 4 111 747 | ||||
| 2019-05-13 | 2019-05-09 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | ACRS | Common Stock | I | 6,1575 | -172 800 | -1 064 | 1 238 828 | ||||
| 2019-05-13 | 2019-05-09 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Common Stock | I | 6,1575 | -261 345 | -1 609 | 4 220 443 | ||||
| 2019-03-04 | 2019-03-01 | 4 | Shanler Stuart | ACRS | Restricted stock units | D | 82 200 | 82 200 | ||||||
| 2019-03-04 | 2019-03-01 | 4 | Gordon David N. | ACRS | Restricted stock units | D | 82 400 | 82 400 | ||||||
| 2019-03-04 | 2019-03-01 | 4 | Ruffo Frank | ACRS | Restricted stock units | D | 103 000 | 103 000 | ||||||
| 2019-03-04 | 2019-03-01 | 4 | Walker Neal | ACRS | Restricted stock units | D | 384 600 | 384 600 | ||||||
| 2019-03-04 | 2019-03-01 | 4 | Ali-Jackson Kamil | ACRS | Restricted stock units | D | 68 700 | 68 700 | ||||||
| 2019-02-05 | 2019-02-01 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Units | D | -3 875 | 11 625 | ||||||
| 2019-02-05 | 2019-02-01 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 6,9600 | -1 308 | -9 | 82 212 | ||||
| 2019-02-05 | 2019-02-01 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 3 875 | 83 520 | ||||||
| 2019-02-05 | 2019-02-01 | 4 | Fair Brett | ACRS | Restricted Stock Units | D | -3 875 | 11 625 | ||||||
| 2019-02-05 | 2019-02-01 | 4 | Fair Brett | ACRS | Common Stock | D | 6,9600 | -1 308 | -9 | 10 582 | ||||
| 2019-02-05 | 2019-02-01 | 4 | Fair Brett | ACRS | Common Stock | D | 3 875 | 11 890 | ||||||
| 2019-02-05 | 2019-02-01 | 4 | Ruffo Frank | ACRS | Restricted Stock Units | D | -3 875 | 11 625 | ||||||
| 2019-02-05 | 2019-02-01 | 4 | Ruffo Frank | ACRS | Common Stock | D | 6,9600 | -1 308 | -9 | 164 976 | ||||
| 2019-02-05 | 2019-02-01 | 4 | Ruffo Frank | ACRS | Common Stock | D | 3 875 | 166 284 | ||||||
| 2019-02-05 | 2019-02-01 | 4 | Shanler Stuart | ACRS | Restricted Stock Units | D | -3 875 | 11 625 | ||||||
| 2019-02-05 | 2019-02-01 | 4 | Shanler Stuart | ACRS | Common Stock | D | 6,9600 | -1 308 | -9 | 272 047 | ||||
| 2019-02-05 | 2019-02-01 | 4 | Shanler Stuart | ACRS | Common Stock | D | 3 875 | 273 355 | ||||||
| 2019-02-05 | 2019-02-01 | 4 | Powala Christopher | ACRS | Restricted Stock Units | D | -3 400 | 10 200 | ||||||
| 2019-02-05 | 2019-02-01 | 4 | Powala Christopher | ACRS | Common Stock | D | 6,9600 | -1 114 | -8 | 141 729 | ||||
| 2019-02-05 | 2019-02-01 | 4 | Powala Christopher | ACRS | Common Stock | D | 3 400 | 142 843 | ||||||
| 2019-02-05 | 2019-02-01 | 4 | Walker Neal | ACRS | Restricted Stock Units | D | -10 800 | 32 400 | ||||||
| 2019-02-05 | 2019-02-01 | 4 | Walker Neal | ACRS | Common Stock | D | 6,9600 | -3 579 | -25 | 917 345 | ||||
| 2019-02-05 | 2019-02-01 | 4 | Walker Neal | ACRS | Common Stock | D | 10 800 | 920 924 | ||||||
| 2019-01-18 | 2019-01-15 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Cash-Settled Total Return Swap | I | 6,93 | 1 | 1 | |||||
| 2019-01-18 | 2019-01-14 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Cash-Settled Total Return Swap | I | 6,97 | 1 | 1 | |||||
| 2019-01-18 | 2019-01-11 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Cash-Settled Total Return Swap | I | 7,00 | 1 | 1 | |||||
| 2019-01-02 | 2018-12-28 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Cash-Settled Total Return Swap | I | 7,00 | 1 | 1 | |||||
| 2018-12-27 | 2018-12-27 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Cash-Settled Total Return Swap | I | 6,89 | 1 | 1 | |||||
| 2018-12-27 | 2018-12-26 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Cash-Settled Total Return Swap | I | 6,86 | 1 | 1 | |||||
| 2018-12-27 | 2018-12-24 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Cash-Settled Total Return Swap | I | 6,92 | 1 | 1 | |||||
| 2018-12-21 | 2018-12-21 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Cash-Settled Total Return Swap | I | 6,94 | 1 | 1 | |||||
| 2018-12-21 | 2018-12-20 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Cash-Settled Total Return Swap | I | 6,84 | 1 | 1 | |||||
| 2018-12-21 | 2018-12-19 | 4 | Flynn James E Through Deerfield Partners, L.P. | ACRS | Cash-Settled Total Return Swap | I | 6,91 | 1 | 1 | |||||
| 2018-12-21 | 2018-12-18 | 4 | Powala Christopher | ACRS | Restricted Stock Units | D | -1 625 | 1 625 | ||||||
| 2018-12-21 | 2018-12-18 | 4 | Powala Christopher | ACRS | Common Stock | D | 6,3000 | -446 | -3 | 139 443 | ||||
| 2018-12-21 | 2018-12-18 | 4 | Powala Christopher | ACRS | Common Stock | D | 1 625 | 139 889 | ||||||
| 2018-12-21 | 2018-12-18 | 4 | Fair Brett | ACRS | Restricted Stock Units | D | -1 750 | 1 750 | ||||||
| 2018-12-21 | 2018-12-18 | 4 | Fair Brett | ACRS | Common Stock | D | 6,3000 | -498 | -3 | 8 015 | ||||
| 2018-12-21 | 2018-12-18 | 4 | Fair Brett | ACRS | Common Stock | D | 1 750 | 8 513 | ||||||
| 2018-12-21 | 2018-12-18 | 4 | Shanler Stuart | ACRS | Restricted Stock Units | D | -1 450 | 1 450 | ||||||
| 2018-12-21 | 2018-12-18 | 4 | Shanler Stuart | ACRS | Common Stock | D | 6,3000 | -412 | -3 | 269 480 | ||||
| 2018-12-21 | 2018-12-18 | 4 | Shanler Stuart | ACRS | Common Stock | D | 1 450 | 269 892 | ||||||
| 2018-12-21 | 2018-12-18 | 4 | Walker Neal | ACRS | Restricted Stock Units | D | -2 925 | 2 925 | ||||||
| 2018-12-21 | 2018-12-18 | 4 | Walker Neal | ACRS | Common Stock | D | 6,3000 | -833 | -5 | 910 124 | ||||
| 2018-12-21 | 2018-12-18 | 4 | Walker Neal | ACRS | Common Stock | D | 2 925 | 910 957 | ||||||
| 2018-12-21 | 2018-12-18 | 4 | Ruffo Frank | ACRS | Restricted Stock Units | D | -1 250 | 1 250 | ||||||
| 2018-12-21 | 2018-12-18 | 4 | Ruffo Frank | ACRS | Common Stock | D | 6,3000 | -356 | -2 | 162 409 | ||||
| 2018-12-21 | 2018-12-18 | 4 | Ruffo Frank | ACRS | Common Stock | D | 1 250 | 162 765 | ||||||
| 2018-12-20 | 2018-12-18 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Units | D | -1 075 | 1 075 | ||||||
| 2018-12-20 | 2018-12-18 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 6,3000 | -306 | -2 | 79 645 | ||||
| 2018-12-20 | 2018-12-18 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 1 075 | 79 951 | ||||||
| 2018-12-18 | 2018-12-15 | 4 | Ruffo Frank | ACRS | Restricted Stock Units | D | -1 300 | 2 600 | ||||||
| 2018-12-18 | 2018-12-15 | 4 | Ruffo Frank | ACRS | Common Stock | D | 7,3100 | -370 | -3 | 161 515 | ||||
| 2018-12-18 | 2018-12-15 | 4 | Ruffo Frank | ACRS | Common Stock | D | 1 300 | 161 885 | ||||||
| 2018-12-18 | 2018-12-15 | 4 | Walker Neal | ACRS | Restricted Stock Units | D | -3 033 | 6 067 | ||||||
| 2018-12-18 | 2018-12-15 | 4 | Walker Neal | ACRS | Common Stock | D | 7,3100 | -863 | -6 | 908 032 | ||||
| 2018-12-18 | 2018-12-15 | 4 | Walker Neal | ACRS | Common Stock | D | 3 033 | 908 895 | ||||||
| 2018-12-18 | 2018-12-15 | 4 | Fair Brett | ACRS | Restricted Stock Units | D | -1 013 | 2 025 | ||||||
| 2018-12-18 | 2018-12-15 | 4 | Fair Brett | ACRS | Common Stock | D | 7,3100 | -288 | -2 | 6 763 | ||||
| 2018-12-18 | 2018-12-15 | 4 | Fair Brett | ACRS | Common Stock | D | 1 013 | 7 051 | ||||||
| 2018-12-18 | 2018-12-15 | 4 | Powala Christopher | ACRS | Restricted Stock Units | D | -1 300 | 2 600 | ||||||
| 2018-12-18 | 2018-12-15 | 4 | Powala Christopher | ACRS | Common Stock | D | 7,3100 | -357 | -3 | 138 264 | ||||
| 2018-12-18 | 2018-12-15 | 4 | Powala Christopher | ACRS | Common Stock | D | 1 300 | 138 621 | ||||||
| 2018-12-18 | 2018-12-15 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Units | D | -1 733 | 3 467 | ||||||
| 2018-12-18 | 2018-12-15 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 7,3100 | -493 | -4 | 78 876 | ||||
| 2018-12-18 | 2018-12-15 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 1 733 | 79 369 | ||||||
| 2018-12-18 | 2018-12-15 | 4 | Shanler Stuart | ACRS | Restricted Stock Units | D | -1 300 | 2 600 | ||||||
| 2018-12-18 | 2018-12-15 | 4 | Shanler Stuart | ACRS | Common Stock | D | 7,3100 | -370 | -3 | 268 442 | ||||
| 2018-12-18 | 2018-12-15 | 4 | Shanler Stuart | ACRS | Common Stock | D | 1 300 | 268 812 | ||||||
| 2018-10-24 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Partners, L.P. | ACRS | Common stock | I | 10 375 204 | ||||||||
| 2018-10-24 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | ACRS | Common stock | I | 7 305 044 | ||||||||
| 2018-10-24 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | ACRS | Common stock | I | 7 305 044 | ||||||||
| 2018-10-24 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Partners, L.P. | ACRS | Common stock | I | 10 375 204 | ||||||||
| 2018-10-24 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | ACRS | Common stock | I | 7 305 044 | ||||||||
| 2018-10-24 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Partners, L.P. | ACRS | Common stock | I | 10 375 204 | ||||||||
| 2018-10-24 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | ACRS | Common stock | I | 7 305 044 | ||||||||
| 2018-10-24 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Partners, L.P. | ACRS | Common stock | I | 10 375 204 | ||||||||
| 2018-10-24 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Partners, L.P. | ACRS | Common stock | I | 10 375 204 | ||||||||
| 2018-10-24 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | ACRS | Common stock | I | 7 305 044 | ||||||||
| 2018-10-24 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | ACRS | Common stock | I | 7 305 044 | ||||||||
| 2018-10-24 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Partners, L.P. | ACRS | Common stock | I | 10 375 204 | ||||||||
| 2018-10-24 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Partners, L.P. | ACRS | Common stock | I | 10 375 204 | ||||||||
| 2018-10-24 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | ACRS | Common stock | I | 7 305 044 | ||||||||
| 2018-10-23 | 2018-10-22 | 4 | Mehra Anand | ACRS | Common Stock | I | 10,7500 | 372 093 | 4 000 | 1 911 573 | ||||
| 2018-10-05 | 2018-10-04 | 4 | Tullman Stephen A. | ACRS | Common Stock | D | 13,9958 | 7 100 | 99 | 177 457 | ||||
| 2018-08-27 | 2018-08-23 | 4 | Tullman Stephen A. | ACRS | Common Stock | D | 14,9977 | 6 600 | 99 | 170 357 | ||||
| 2018-08-17 | 2018-08-15 | 4 | Tullman Stephen A. | ACRS | Common Stock | D | 15,9700 | 6 250 | 100 | 163 757 | ||||
| 2018-06-12 | 2018-06-12 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 20,0000 | -4 900 | -98 | 77 636 | ||||
| 2018-06-12 | 2018-06-11 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 20,0000 | -100 | -2 | 82 536 | ||||
| 2018-06-08 | 2018-06-07 | 4 | Mehra Anand | ACRS | Stock Option (right to buy) | D | 18,35 | 8 000 | 8 000 | |||||
| 2018-06-08 | 2018-06-07 | 4 | Humphries William D. | ACRS | Stock Option (right to buy) | D | 18,35 | 8 000 | 8 000 | |||||
| 2018-06-08 | 2018-06-07 | 4 | Molineaux Christopher P. | ACRS | Stock Option (right to buy) | D | 18,35 | 8 000 | 8 000 | |||||
| 2018-06-08 | 2018-06-07 | 4 | Powell Andrew Kenneth William | ACRS | Stock Option (right to buy) | D | 18,35 | 8 000 | 8 000 | |||||
| 2018-06-08 | 2018-06-07 | 4 | SCHIFF ANDREW N | ACRS | Stock Option (right to buy) | D | 18,35 | 8 000 | 8 000 | |||||
| 2018-05-21 | 2018-05-18 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 20,0000 | -10 000 | -200 | 82 636 | ||||
| 2018-05-17 | 2018-05-16 | 4 | Powell Andrew Kenneth William | ACRS | Common Stock | D | 19,1200 | 500 | 10 | 500 | ||||
| 2018-05-09 | 2018-05-07 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Units | D | -6 933 | 5 200 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 18,1000 | -1 974 | -36 | 92 636 | ||||
| 2018-05-09 | 2018-05-07 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 6 933 | 94 610 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Fair Brett | ACRS | Restricted Stock Units | D | -4 050 | 3 038 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Fair Brett | ACRS | Common Stock | D | 18,1000 | -1 153 | -21 | 6 038 | ||||
| 2018-05-09 | 2018-05-07 | 4 | Fair Brett | ACRS | Common Stock | D | 4 050 | 7 191 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Powala Christopher | ACRS | Restricted Stock Units | D | -5 200 | 3 900 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Powala Christopher | ACRS | Common Stock | D | 18,1000 | -1 480 | -27 | 137 321 | ||||
| 2018-05-09 | 2018-05-07 | 4 | Powala Christopher | ACRS | Common Stock | D | 5 200 | 138 801 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Ruffo Frank | ACRS | Restricted Stock Units | D | -5 200 | 3 900 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Ruffo Frank | ACRS | Common Stock | D | 18,1000 | -1 480 | -27 | 160 585 | ||||
| 2018-05-09 | 2018-05-07 | 4 | Ruffo Frank | ACRS | Common Stock | D | 5 200 | 162 065 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Shanler Stuart | ACRS | Restricted Stock Units | D | -5 200 | 3 900 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Shanler Stuart | ACRS | Common Stock | D | 18,1000 | -1 480 | -27 | 267 512 | ||||
| 2018-05-09 | 2018-05-07 | 4 | Shanler Stuart | ACRS | Common Stock | D | 5 200 | 268 992 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Walker Neal | ACRS | Restricted Stock Units | D | -12 133 | 9 100 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Walker Neal | ACRS | Common Stock | D | 18,1000 | -3 455 | -63 | 905 862 | ||||
| 2018-05-09 | 2018-05-07 | 4 | Walker Neal | ACRS | Common Stock | D | 12 133 | 909 317 | ||||||
| 2018-05-07 | 2018-05-07 | 4 | Ruffo Frank | ACRS | Common Stock | D | 18,2200 | 1 250 | 23 | 156 865 | ||||
| 2018-04-23 | 2018-04-20 | 4 | Reasons Bryan M. | ACRS | Stock Option (right to buy) | D | 17,73 | 16 000 | 16 000 | |||||
| 2018-04-17 | 3 | Fair Brett | ACRS | Common Stock | D | 6 282 | ||||||||
| 2018-04-17 | 3 | Fair Brett | ACRS | Common Stock | D | 6 282 | ||||||||
| 2018-04-17 | 3 | Fair Brett | ACRS | Common Stock | D | 6 282 | ||||||||
| 2018-04-09 | 2018-04-06 | 4 | Molineaux Christopher P. | ACRS | Common Stock | D | 16,5200 | 2 300 | 38 | 7 682 | ||||
| 2018-04-09 | 2018-04-06 | 4 | Tullman Stephen A. | ACRS | Common Stock | D | 16,5400 | 26 700 | 442 | 157 507 | ||||
| 2018-04-09 | 2018-04-06 | 4 | Ruffo Frank | ACRS | Common Stock | D | 16,5900 | 1 250 | 21 | 155 615 | ||||
| 2018-04-09 | 2018-04-05 | 4 | Walker Neal | ACRS | Common Stock | D | 16,7500 | 10 000 | 168 | 897 184 | ||||
| 2018-03-22 | 2018-03-20 | 4 | Molineaux Christopher P. | ACRS | Stock option (right to buy) | D | 1,52 | -264 | 198 | |||||
| 2018-03-22 | 2018-03-20 | 4 | Molineaux Christopher P. | ACRS | Stock option (right to buy) | D | 0,72 | -120 | 51 | |||||
| 2018-03-22 | 2018-03-20 | 4 | Molineaux Christopher P. | ACRS | Stock option (right to buy) | D | 0,41 | -1 993 | 0 | |||||
| 2018-03-22 | 2018-03-20 | 4 | Molineaux Christopher P. | ACRS | Common Stock | D | 1,5200 | 264 | 0 | 9 982 | ||||
| 2018-03-22 | 2018-03-20 | 4 | Molineaux Christopher P. | ACRS | Common Stock | D | 0,7200 | 120 | 0 | 9 718 | ||||
| 2018-03-22 | 2018-03-20 | 4 | Molineaux Christopher P. | ACRS | Common Stock | D | 0,4100 | 1 993 | 1 | 9 598 | ||||
| 2018-03-20 | 2018-03-16 | 4 | Walker Neal | ACRS | Common Stock | D | 9 018 | 887 184 | ||||||
| 2018-03-20 | 2018-03-16 | 4 | Ruffo Frank | ACRS | Common Stock | D | 9 018 | 154 365 | ||||||
| 2018-03-20 | 2018-03-16 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 9 018 | 87 677 | ||||||
| 2018-03-20 | 2018-03-16 | 4 | Tullman Stephen A. | ACRS | Common Stock | D | 9 018 | 130 807 | ||||||
| 2018-03-20 | 2018-03-16 | 4 | Tullman Stephen A. By NST, LLC | ACRS | Common Stock | I | -94 151 | 0 | ||||||
| 2018-02-05 | 2018-02-01 | 4 | Walker Neal | ACRS | Restricted stock units | D | 43 200 | 43 200 | ||||||
| 2018-02-05 | 2018-02-01 | 4 | Walker Neal | ACRS | Stock option (right to buy) | D | 22,09 | 151 200 | 151 200 | |||||
| 2018-02-05 | 2018-02-01 | 4 | Ali-Jackson Kamil | ACRS | Restricted stock units | D | 15 500 | 15 500 | ||||||
| 2018-02-05 | 2018-02-01 | 4 | Ali-Jackson Kamil | ACRS | Stock option (right to buy) | D | 22,09 | 54 000 | 54 000 | |||||
| 2018-02-05 | 2018-02-01 | 4 | Shanler Stuart | ACRS | Restricted stock units | D | 15 500 | 15 500 | ||||||
| 2018-02-05 | 2018-02-01 | 4 | Shanler Stuart | ACRS | Stock option (right to buy) | D | 22,09 | 54 000 | 54 000 | |||||
| 2018-02-05 | 2018-02-01 | 4 | Ruffo Frank | ACRS | Restricted stock units | D | 15 500 | 15 500 | ||||||
| 2018-02-05 | 2018-02-01 | 4 | Ruffo Frank | ACRS | Stock option (right to buy) | D | 22,09 | 54 000 | 54 000 | |||||
| 2018-02-05 | 2018-02-01 | 4 | Powala Christopher | ACRS | Restricted stock units | D | 13 600 | 13 600 | ||||||
| 2018-02-05 | 2018-02-01 | 4 | Powala Christopher | ACRS | Stock option (right to buy) | D | 22,09 | 47 600 | 47 600 | |||||
| 2017-12-21 | 2017-12-18 | 4 | Shanler Stuart | ACRS | Restricted Stock Units | D | -1 450 | 2 900 | ||||||
| 2017-12-21 | 2017-12-18 | 4 | Shanler Stuart | ACRS | Common Stock | D | 24,1200 | -441 | -11 | 263 792 | ||||
| 2017-12-21 | 2017-12-18 | 4 | Shanler Stuart | ACRS | Common Stock | D | 1 450 | 264 233 | ||||||
| 2017-12-21 | 2017-12-15 | 4 | Shanler Stuart | ACRS | Restricted Stock Units | D | -1 300 | 9 100 | ||||||
| 2017-12-21 | 2017-12-15 | 4 | Shanler Stuart | ACRS | Common Stock | D | 24,2300 | -395 | -10 | 262 783 | ||||
| 2017-12-21 | 2017-12-15 | 4 | Shanler Stuart | ACRS | Common Stock | D | 1 300 | 263 178 | ||||||
| 2017-12-21 | 2017-12-18 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Units | D | -1 075 | 2 150 | ||||||
| 2017-12-21 | 2017-12-18 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 24,1200 | -327 | -8 | 78 659 | ||||
| 2017-12-21 | 2017-12-18 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 1 075 | 78 986 | ||||||
| 2017-12-21 | 2017-12-15 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Units | D | -1 733 | 12 133 | ||||||
| 2017-12-21 | 2017-12-15 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 24,2300 | -527 | -13 | 77 911 | ||||
| 2017-12-21 | 2017-12-15 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 1 733 | 78 438 | ||||||
| 2017-12-21 | 2017-12-18 | 4 | Powala Christopher | ACRS | Restricted Stock Units | D | -1 625 | 3 250 | ||||||
| 2017-12-21 | 2017-12-18 | 4 | Powala Christopher | ACRS | Common Stock | D | 24,1200 | -494 | -12 | 133 601 | ||||
| 2017-12-21 | 2017-12-18 | 4 | Powala Christopher | ACRS | Common Stock | D | 1 625 | 134 095 | ||||||
| 2017-12-21 | 2017-12-15 | 4 | Powala Christopher | ACRS | Restricted Stock Units | D | -1 300 | 9 100 | ||||||
| 2017-12-21 | 2017-12-15 | 4 | Powala Christopher | ACRS | Common Stock | D | 24,2300 | -395 | -10 | 132 470 | ||||
| 2017-12-21 | 2017-12-15 | 4 | Powala Christopher | ACRS | Common Stock | D | 1 300 | 132 865 | ||||||
| 2017-12-21 | 2017-12-18 | 4 | Ruffo Frank | ACRS | Restricted Stock Units | D | -1 250 | 2 500 | ||||||
| 2017-12-21 | 2017-12-18 | 4 | Ruffo Frank | ACRS | Common Stock | D | 24,1200 | -380 | -9 | 145 347 | ||||
| 2017-12-21 | 2017-12-18 | 4 | Ruffo Frank | ACRS | Common Stock | D | 1 250 | 145 727 | ||||||
| 2017-12-21 | 2017-12-15 | 4 | Ruffo Frank | ACRS | Restricted Stock Units | D | -1 300 | 9 100 | ||||||
| 2017-12-21 | 2017-12-15 | 4 | Ruffo Frank | ACRS | Common Stock | D | 24,2300 | -395 | -10 | 144 477 | ||||
| 2017-12-21 | 2017-12-15 | 4 | Ruffo Frank | ACRS | Common Stock | D | 1 300 | 144 872 | ||||||
| 2017-12-21 | 2017-12-18 | 4 | Walker Neal | ACRS | Restricted Stock Units | D | -2 925 | 5 850 | ||||||
| 2017-12-21 | 2017-12-18 | 4 | Walker Neal | ACRS | Common Stock | D | 24,1200 | -889 | -21 | 878 166 | ||||
| 2017-12-21 | 2017-12-18 | 4 | Walker Neal | ACRS | Common Stock | D | 2 925 | 879 055 | ||||||
| 2017-12-21 | 2017-12-15 | 4 | Walker Neal | ACRS | Restricted Stock Units | D | -3 033 | 21 233 | ||||||
| 2017-12-21 | 2017-12-15 | 4 | Walker Neal | ACRS | Common Stock | D | 24,2300 | -922 | -22 | 876 130 | ||||
| 2017-12-21 | 2017-12-15 | 4 | Walker Neal | ACRS | Common Stock | D | 3 033 | 877 052 | ||||||
| 2017-08-18 | 3 | FMR LLC / Fidelity Management & Research F-Prime Capital Partners Healthcare Fund III LP | ACRS | Common Stock | I | 630 960 | ||||||||
| 2017-08-18 | 3 | FMR LLC / Fidelity Management & Research F-Prime Capital Partners Healthcare Advisors Fund III LP | ACRS | Common Stock | I | 342 282 | ||||||||
| 2017-08-18 | 3 | FMR LLC / Fidelity Management & Research FIMM, LLC | ACRS | Common Stock | I | 326 917 | ||||||||
| 2017-08-18 | 3 | FMR LLC / Fidelity Management & Research F-Prime Inc | ACRS | Common Stock | I | 332 926 | ||||||||
| 2017-08-18 | 3 | FMR LLC / Fidelity Management & Research F-Prime Capital Partners Healthcare Advisors Fund III LP | ACRS | Common Stock | I | 342 282 | ||||||||
| 2017-08-18 | 3 | FMR LLC / Fidelity Management & Research F-Prime Inc | ACRS | Common Stock | I | 332 926 | ||||||||
| 2017-08-18 | 3 | FMR LLC / Fidelity Management & Research F-Prime Capital Partners Healthcare Fund III LP | ACRS | Common Stock | I | 630 960 | ||||||||
| 2017-08-18 | 3 | FMR LLC / Fidelity Management & Research FIMM, LLC | ACRS | Common Stock | I | 326 917 | ||||||||
| 2017-08-16 | 2017-08-16 | 4 | SCHIFF ANDREW N By Aisling Capital IV LP | ACRS | Common Stock | I | 23,0200 | 108 601 | 2 500 | 634 455 | ||||
| 2017-08-14 | 3 | SCHIFF ANDREW N By Aisling Capital IV LP | ACRS | Common Stock | I | 1 051 708 | ||||||||
| 2017-08-14 | 3 | SCHIFF ANDREW N By Aisling Capital IV LP | ACRS | Common Stock | I | 1 051 708 | ||||||||
| 2017-08-14 | 2017-08-09 | 4 | SCHIFF ANDREW N | ACRS | Stock Option (right to buy) | D | 26,97 | 16 000 | 16 000 | |||||
| 2017-06-16 | 2017-06-15 | 4 | Powell Andrew Kenneth William | ACRS | Stock Option (right to buy) | D | 24,58 | 8 000 | 8 000 | |||||
| 2017-06-16 | 2017-06-15 | 4 | Humphries William D. | ACRS | Stock Option (right to buy) | D | 24,58 | 8 000 | 8 000 | |||||
| 2017-06-16 | 2017-06-15 | 4 | Bierly Rick | ACRS | Stock Option (right to buy) | D | 24,58 | 8 000 | 8 000 | |||||
| 2017-06-16 | 2017-06-15 | 4 | Mehra Anand | ACRS | Stock Option (right to buy) | D | 24,58 | 8 000 | 8 000 | |||||
| 2017-06-16 | 2017-06-15 | 4 | Molineaux Christopher P. | ACRS | Stock Option (right to buy) | D | 24,58 | 8 000 | 8 000 | |||||
| 2017-03-21 | 2017-03-17 | 4 | Molineaux Christopher P. | ACRS | Stock option (right to buy) | D | 0,72 | -311 | 171 | |||||
| 2017-03-21 | 2017-03-17 | 4 | Molineaux Christopher P. | ACRS | Stock option (right to buy) | D | 1,52 | -592 | 462 | |||||
| 2017-03-21 | 2017-03-17 | 4 | Molineaux Christopher P. | ACRS | Stock option (right to buy) | D | 0,41 | -6 702 | 1 993 | |||||
| 2017-03-21 | 2017-03-17 | 4 | Molineaux Christopher P. | ACRS | Common Stock | D | 0,7200 | 311 | 0 | 7 605 | ||||
| 2017-03-21 | 2017-03-17 | 4 | Molineaux Christopher P. | ACRS | Common Stock | D | 1,5200 | 592 | 1 | 7 294 | ||||
| 2017-03-21 | 2017-03-17 | 4 | Molineaux Christopher P. | ACRS | Common Stock | D | 0,4100 | 6 702 | 3 | 6 702 | ||||
| 2017-03-02 | 2017-03-02 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P. | ACRS | Common Stock | I | 31,2000 | -2 666 | -83 | 60 972 | ||||
| 2017-03-02 | 2017-03-02 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P. | ACRS | Common Stock | I | 31,2000 | -122 334 | -3 817 | 2 797 597 | ||||
| 2017-03-02 | 2017-03-01 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P. | ACRS | Common Stock | I | 30,9800 | -2 133 | -66 | 63 638 | ||||
| 2017-03-02 | 2017-03-01 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P. | ACRS | Common Stock | I | 30,9800 | -97 867 | -3 032 | 2 919 931 | ||||
| 2017-03-02 | 2017-02-28 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P. | ACRS | Common Stock | I | 30,5000 | -4 266 | -130 | 65 771 | ||||
| 2017-03-02 | 2017-02-28 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P. | ACRS | Common Stock | I | 30,5000 | -195 734 | -5 970 | 3 017 798 | ||||
| 2017-01-26 | 2017-01-25 | 4 | Powell Andrew Kenneth William | ACRS | Stock Option (right to buy) | D | 27,30 | 16 000 | 16 000 | |||||
| 2017-01-12 | 2017-01-10 | 4 | Mehra Anand By Funds | ACRS | Common Stock | I | 28,2511 | -750 000 | -21 188 | 1 539 480 | ||||
| 2016-12-21 | 2016-12-19 | 4 | FMR LLC / Fidelity Management & Research | ACRS | Common Stock | I | -639 627 | 1 931 727 | ||||||
| 2016-12-20 | 2016-12-18 | 4 | Walker Neal | ACRS | Restricted Stock Units | D | -2 925 | 8 775 | ||||||
| 2016-12-20 | 2016-12-18 | 4 | Walker Neal | ACRS | Common Stock | D | 31,2500 | -889 | -28 | 874 019 | ||||
| 2016-12-20 | 2016-12-18 | 4 | Walker Neal | ACRS | Common Stock | D | 2 925 | 874 908 | ||||||
| 2016-12-20 | 2016-12-18 | 4 | Powala Christopher | ACRS | Restricted Stock Units | D | -1 625 | 4 875 | ||||||
| 2016-12-20 | 2016-12-18 | 4 | Powala Christopher | ACRS | Common Stock | D | 31,2500 | -494 | -15 | 131 565 | ||||
| 2016-12-20 | 2016-12-18 | 4 | Powala Christopher | ACRS | Common Stock | D | 1 625 | 132 059 | ||||||
| 2016-12-20 | 2016-12-18 | 4 | Shanler Stuart | ACRS | Restricted Stock Units | D | -1 450 | 4 350 | ||||||
| 2016-12-20 | 2016-12-18 | 4 | Shanler Stuart | ACRS | Common Stock | D | 31,2500 | -441 | -14 | 261 878 | ||||
| 2016-12-20 | 2016-12-18 | 4 | Shanler Stuart | ACRS | Common Stock | D | 1 450 | 262 319 | ||||||
| 2016-12-20 | 2016-12-18 | 4 | Ali-Jackson Kamil | ACRS | Restricted Stock Units | D | -1 075 | 3 225 | ||||||
| 2016-12-20 | 2016-12-18 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 31,2500 | -327 | -10 | 76 705 | ||||
| 2016-12-20 | 2016-12-18 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 1 075 | 77 032 | ||||||
| 2016-12-20 | 2016-12-18 | 4 | Ruffo Frank | ACRS | Restricted Stock Units | D | -1 250 | 3 750 | ||||||
| 2016-12-20 | 2016-12-18 | 4 | Ruffo Frank | ACRS | Common Stock | D | 31,2500 | -380 | -12 | 143 572 | ||||
| 2016-12-20 | 2016-12-18 | 4 | Ruffo Frank | ACRS | Common Stock | D | 1 250 | 143 952 | ||||||
| 2016-12-19 | 2016-12-15 | 4 | Walker Neal | ACRS | Restricted stock units | D | 24 266 | 24 266 | ||||||
| 2016-12-19 | 2016-12-15 | 4 | Walker Neal | ACRS | Stock option (right to buy) | D | 28,92 | 145 600 | 145 600 | |||||
| 2016-12-19 | 2016-12-15 | 4 | Powala Christopher | ACRS | Restricted stock units | D | 10 400 | 10 400 | ||||||
| 2016-12-19 | 2016-12-15 | 4 | Powala Christopher | ACRS | Stock option (right to buy) | D | 28,92 | 62 400 | 62 400 | |||||
| 2016-12-19 | 2016-12-15 | 4 | Shanler Stuart | ACRS | Restricted stock units | D | 10 400 | 10 400 | ||||||
| 2016-12-19 | 2016-12-15 | 4 | Shanler Stuart | ACRS | Stock option (right to buy) | D | 28,92 | 62 400 | 62 400 | |||||
| 2016-12-19 | 2016-12-15 | 4 | Ali-Jackson Kamil | ACRS | Restricted stock units | D | 13 866 | 13 866 | ||||||
| 2016-12-19 | 2016-12-15 | 4 | Ali-Jackson Kamil | ACRS | Stock option (right to buy) | D | 28,92 | 83 200 | 83 200 | |||||
| 2016-12-19 | 2016-12-15 | 4 | Ruffo Frank | ACRS | Restricted stock units | D | 10 400 | 10 400 | ||||||
| 2016-12-19 | 2016-12-15 | 4 | Ruffo Frank | ACRS | Stock option (right to buy) | D | 28,92 | 62 400 | 62 400 | |||||
| 2016-11-18 | 2016-11-18 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P. | ACRS | Common Stock | I | 22,7200 | -9 598 | -218 | 70 037 | ||||
| 2016-11-18 | 2016-11-18 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P. | ACRS | Common Stock | I | 22,7200 | -440 402 | -10 006 | 3 213 532 | ||||
| 2016-11-18 | 2016-11-16 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P. | ACRS | Common Stock | I | 27,3000 | -9 765 | -267 | 79 635 | ||||
| 2016-11-18 | 2016-11-16 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P. | ACRS | Common Stock | I | 23,2500 | -448 063 | -10 417 | 3 653 934 | ||||
| 2016-10-28 | 2016-10-26 | 4 | Ali-Jackson Kamil | ACRS | Employee StockOption (right to buy) | D | 1,52 | -3 912 | 6 522 | |||||
| 2016-10-28 | 2016-10-26 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 21,8300 | -3 912 | -85 | 75 957 | ||||
| 2016-10-28 | 2016-10-26 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 1,5200 | 3 912 | 6 | 79 869 | ||||
| 2016-10-28 | 2016-10-26 | 4 | FMR LLC / Fidelity Management & Research | ACRS | Common Stock | I | 22,1500 | -100 | -2 | 2 571 354 | ||||
| 2016-10-28 | 2016-10-26 | 4 | FMR LLC / Fidelity Management & Research | ACRS | Common Stock | I | 21,9300 | -3 650 | -80 | 2 571 454 | ||||
| 2016-10-20 | 2016-10-19 | 4 | FMR LLC / Fidelity Management & Research See Footnote 1 | ACRS | Common Stock | I | -84 223 | 2 575 104 | ||||||
| 2016-09-28 | 2016-09-28 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 24,6600 | -1 841 | -45 | 75 957 | ||||
| 2016-09-28 | 2016-09-28 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 0,7200 | 1 841 | 1 | 77 798 | ||||
| 2016-09-28 | 2016-09-26 | 4 | Ali-Jackson Kamil | ACRS | Employee StockOption (right to buy) | D | 0,72 | -1 841 | 2 176 | |||||
| 2016-09-19 | 2016-09-16 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 24,5429 | -23 600 | -579 | 2 102 169 | ||||
| 2016-09-19 | 2016-09-16 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 24,5000 | -150 000 | -3 675 | 2 125 769 | ||||
| 2016-09-19 | 2016-09-15 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 24,2000 | -58 950 | -1 427 | 2 275 769 | ||||
| 2016-09-19 | 2016-09-15 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 24,0000 | -273 000 | -6 552 | 2 334 719 | ||||
| 2016-09-19 | 2016-09-15 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 24,0350 | -20 000 | -481 | 2 607 719 | ||||
| 2016-09-19 | 2016-09-15 | 4 | Walker Neal | ACRS | Common Stock | D | 4 790 | 871 983 | ||||||
| 2016-09-19 | 2016-09-15 | 4 | Walker Neal | ACRS | Common Stock | D | 81 686 | 867 193 | ||||||
| 2016-09-19 | 2016-09-15 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 4 790 | 75 957 | ||||||
| 2016-09-19 | 2016-09-15 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 50 878 | 71 167 | ||||||
| 2016-09-19 | 2016-09-15 | 4 | Tullman Stephen A. | ACRS | Common Stock | D | 4 790 | 121 789 | ||||||
| 2016-09-19 | 2016-09-15 | 4 | Tullman Stephen A. By NST, LLC | ACRS | Common Stock | I | -50 002 | 94 151 | ||||||
| 2016-09-19 | 2016-09-15 | 4 | Tullman Stephen A. By NST, LLC | ACRS | Common Stock | I | 144 153 | 144 153 | ||||||
| 2016-09-19 | 2016-09-15 | 4 | Tullman Stephen A. | ACRS | Common Stock | D | 116 999 | 116 999 | ||||||
| 2016-09-19 | 2016-09-15 | 4 | Tullman Stephen A. By NeXeption, LLC | ACRS | Common Stock | I | -521 739 | 0 | ||||||
| 2016-09-19 | 2016-09-15 | 4 | Ruffo Frank | ACRS | Common Stock | D | 4 790 | 142 702 | ||||||
| 2016-09-02 | 2016-09-01 | 4 | Humphries William D. | ACRS | Stock Option (right to buy) | D | 20,68 | 10 000 | 10 000 | |||||
| 2016-08-31 | 2016-08-30 | 4 | FMR LLC / Fidelity Management & Research See Footnote 1 | ACRS | Common Stock | I | -130 571 | 2 659 327 | ||||||
| 2016-08-29 | 2016-08-26 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 20,3500 | -3 738 | -76 | 20 289 | ||||
| 2016-07-01 | 2016-06-29 | 4 | CHA ALBERT | ACRS | Stock Option (right to buy) | D | 18,32 | 6 632 | 6 632 | |||||
| 2016-07-01 | 2016-06-29 | 4 | Mehra Anand | ACRS | Stock Option (right to buy) | D | 18,32 | 6 632 | 6 632 | |||||
| 2016-07-01 | 2016-06-29 | 4 | Bierly Rick | ACRS | Stock Option (right to buy) | D | 18,32 | 6 632 | 6 632 | |||||
| 2016-07-01 | 2016-06-29 | 4 | Molineaux Christopher P. | ACRS | Stock Option (right to buy) | D | 18,32 | 6 632 | 6 632 | |||||
| 2016-04-21 | 2016-04-19 | 4 | FMR LLC / Fidelity Management & Research See Footnote 1 | ACRS | Common Stock | I | -1 014 381 | 2 789 898 | ||||||
| 2016-02-24 | 2016-02-23 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 17,6187 | 28 408 | 501 | 2 627 719 | ||||
| 2016-02-24 | 2016-02-22 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 15,9885 | 11 318 | 181 | 2 599 311 | ||||
| 2016-01-20 | 2016-01-20 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 19,8830 | 1 803 | 36 | 2 587 993 | ||||
| 2016-01-20 | 2016-01-19 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 19,8763 | 4 200 | 83 | 2 586 190 | ||||
| 2016-01-20 | 2016-01-15 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 19,8572 | 1 800 | 36 | 2 581 990 | ||||
| 2016-01-13 | 2016-01-13 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 19,9665 | 5 543 | 111 | 2 580 190 | ||||
| 2016-01-13 | 2016-01-12 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 19,1188 | 5 941 | 114 | 2 574 647 | ||||
| 2016-01-13 | 2016-01-11 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 17,9337 | 4 153 | 74 | 2 568 706 | ||||
| 2015-12-22 | 2015-12-18 | 4 | Walker Neal | ACRS | Restricted stock units | D | 11 700 | 11 700 | ||||||
| 2015-12-22 | 2015-12-18 | 4 | Walker Neal | ACRS | Stock option (right to buy) | D | 28,68 | 137 335 | 137 335 | |||||
| 2015-12-22 | 2015-12-18 | 4 | Molineaux Christopher P. | ACRS | Stock option (right to buy) | D | 28,68 | 2 759 | 2 759 | |||||
| 2015-12-22 | 2015-12-18 | 4 | Ruffo Frank | ACRS | Restricted stock units | D | 5 000 | 5 000 | ||||||
| 2015-12-22 | 2015-12-18 | 4 | Ruffo Frank | ACRS | Stock option (right to buy) | D | 28,68 | 49 439 | 49 439 | |||||
| 2015-12-22 | 2015-12-18 | 4 | Tullman Stephen A. | ACRS | Stock option (right to buy) | D | 28,68 | 7 095 | 7 095 | |||||
| 2015-12-22 | 2015-12-18 | 4 | Ali-Jackson Kamil | ACRS | Restricted stock units | D | 4 300 | 4 300 | ||||||
| 2015-12-22 | 2015-12-18 | 4 | Ali-Jackson Kamil | ACRS | Stock option (right to buy) | D | 28,68 | 45 939 | 45 939 | |||||
| 2015-12-22 | 2015-12-18 | 4 | Shanler Stuart | ACRS | Restricted stock units | D | 5 800 | 5 800 | ||||||
| 2015-12-22 | 2015-12-18 | 4 | Shanler Stuart | ACRS | Stock option (right to buy) | D | 28,68 | 53 833 | 53 833 | |||||
| 2015-12-22 | 2015-12-18 | 4 | Powala Christopher | ACRS | Restricted stock units | D | 6 500 | 6 500 | ||||||
| 2015-12-22 | 2015-12-18 | 4 | Powala Christopher | ACRS | Stock option (right to buy) | D | 28,68 | 58 516 | 58 516 | |||||
| 2015-10-30 | 2015-10-29 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 14,0000 | 95 000 | 1 330 | 2 564 552 | ||||
| 2015-10-30 | 2015-10-28 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 14,0000 | 149 200 | 2 089 | 2 469 552 | ||||
| 2015-10-26 | 2015-10-22 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 14,0264 | 5 410 | 76 | 2 320 352 | ||||
| 2015-10-21 | 2015-10-21 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 14,8311 | 3 100 | 46 | 2 314 942 | ||||
| 2015-10-21 | 2015-10-20 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 14,9491 | 7 965 | 119 | 2 311 842 | ||||
| 2015-10-21 | 2015-10-19 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 14,8763 | 23 934 | 356 | 2 303 877 | ||||
| 2015-10-16 | 2015-10-14 | 4 | RA CAPITAL MANAGEMENT, LLC | ACRS | Common Stock | I | 14,0563 | 42 813 | 602 | 2 279 943 | ||||
| 2015-10-14 | 2015-10-13 | 4 | FMR LLC / Fidelity Management & Research Beacon Bioventures Fund III Limited Partnership | ACRS | Series C Convertible Preferred Stock | I | 1 496 764 | 0 | ||||||
| 2015-10-14 | 2015-10-13 | 4 | FMR LLC / Fidelity Management & Research Beacon Bioventures Fund III Limited Partnership | ACRS | Series B Convertible Preferred Stock | I | 1 818 182 | 0 | ||||||
| 2015-10-14 | 2015-10-13 | 4 | FMR LLC / Fidelity Management & Research Beacon Bioventures Fund III Limited Partnership | ACRS | Series A Convertible Preferred Stock | I | 8 652 500 | 0 | ||||||
| 2015-10-14 | 2015-10-13 | 4 | FMR LLC / Fidelity Management & Research Beacon Bioventures Fund III Limited Partnership | ACRS | Common Stock | I | 11,0000 | 335 455 | 3 690 | 3 804 279 | ||||
| 2015-10-14 | 2015-10-13 | 4 | FMR LLC / Fidelity Management & Research Beacon Bioventures Fund III Limited Partnership | ACRS | Common Stock | I | 433 844 | 3 468 824 | ||||||
| 2015-10-14 | 2015-10-13 | 4 | FMR LLC / Fidelity Management & Research Beacon Bioventures Fund III Limited Partnership | ACRS | Common Stock | I | 527 009 | 3 034 980 | ||||||
| 2015-10-14 | 2015-10-13 | 4 | FMR LLC / Fidelity Management & Research Beacon Bioventures Fund III Limited Partnership | ACRS | Common Stock | I | 2 507 971 | 2 507 971 | ||||||
| 2015-10-13 | 3 | Kolchinsky Peter | ACRS | Common Stock, $0.00001 par value | I | 4 474 260 | ||||||||
| 2015-10-13 | 3 | Kolchinsky Peter | ACRS | Common Stock, $0.00001 par value | I | 4 474 260 | ||||||||
| 2015-10-13 | 3 | Kolchinsky Peter | ACRS | Common Stock, $0.00001 par value | I | 4 474 260 | ||||||||
| 2015-10-13 | 2015-10-13 | 4 | Tullman Stephen A. By Trust | ACRS | Series C Preferred Stock | I | -17 437 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Tullman Stephen A. By Trust | ACRS | Series B Preferred Stock | I | -31 913 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Tullman Stephen A. By Trust | ACRS | Series A Preferred Stock | I | -110 000 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Tullman Stephen A. By Trust | ACRS | Common Stock | I | 46 188 | 394 014 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | CHA ALBERT By funds | ACRS | Series C Preferred Stock | I | -1 375 405 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | CHA ALBERT By funds | ACRS | Series B Preferred Stock | I | -1 818 182 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | CHA ALBERT By funds | ACRS | Series A Preferred Stock | I | -8 652 500 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | CHA ALBERT By funds | ACRS | Common Stock | I | 11,0000 | 454 545 | 5 000 | 4 191 397 | ||||
| 2015-10-13 | 2015-10-13 | 4 | CHA ALBERT By funds | ACRS | Common Stock | I | 3 433 646 | 3 736 852 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P. | ACRS | Series C Preferred Stock | I | -29 337 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P. | ACRS | Series C Preferred Stock | I | -1 346 068 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P. | ACRS | Series B Preferred Stock | I | -38 782 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P. | ACRS | Series B Preferred Stock | I | -1 779 400 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P. | ACRS | Series A Preferred Stock | I | -184 557 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P. | ACRS | Series A Preferred Stock | I | -8 467 943 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P. | ACRS | Common Stock | I | 11,0000 | 9 695 | 107 | 89 400 | ||||
| 2015-10-13 | 2015-10-13 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P. | ACRS | Common Stock | I | 73 238 | 79 705 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P. | ACRS | Common Stock | I | 11,0000 | 444 850 | 4 893 | 4 101 997 | ||||
| 2015-10-13 | 2015-10-13 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P. | ACRS | Common Stock | I | 3 360 408 | 3 657 147 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Mehra Anand By Funds | ACRS | Series C Preferred Stock | I | -2 063 107 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Mehra Anand By Funds | ACRS | Series B Preferred Stock | I | -2 424 242 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Mehra Anand By Funds | ACRS | Series A Preferred Stock | I | -2 000 000 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Mehra Anand By Funds | ACRS | Common Stock | I | 11,0000 | 409 090 | 4 500 | 2 289 480 | ||||
| 2015-10-13 | 2015-10-13 | 4 | Mehra Anand By Funds | ACRS | Common Stock | I | 1 880 390 | 1 880 390 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Ali-Jackson Kamil | ACRS | Series B Preferred Stock | D | -2 901 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Ali-Jackson Kamil | ACRS | Series A Preferred Stock | D | -10 000 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Ali-Jackson Kamil | ACRS | Common Stock | D | 3 738 | 24 027 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Ruffo Frank | ACRS | Series B Preferred Stock | D | -5 802 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Ruffo Frank | ACRS | Series A Preferred Stock | D | -20 000 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Ruffo Frank | ACRS | Common Stock | D | 7 478 | 137 912 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Sofinnova Venture Partners VIII, L.P. | ACRS | Series C Preferred Stock | D | -2 063 107 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Sofinnova Venture Partners VIII, L.P. | ACRS | Series B Preferred Stock | D | -2 424 242 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Sofinnova Venture Partners VIII, L.P. | ACRS | Series A Preferred Stock | D | -2 000 000 | 0 | ||||||
| 2015-10-13 | 2015-10-13 | 4 | Sofinnova Venture Partners VIII, L.P. | ACRS | Common Stock | D | 11,0000 | 409 090 | 4 500 | 2 289 480 | ||||
| 2015-10-13 | 2015-10-13 | 4 | Sofinnova Venture Partners VIII, L.P. | ACRS | Common Stock | D | 1 880 390 | 1 880 390 | ||||||
| 2015-10-13 | 2015-10-08 | 4 | RA CAPITAL MANAGEMENT, LLC See Footnote 1 | ACRS | Common Stock | I | 10,9979 | 21 691 | 239 | 2 237 130 | ||||
| 2015-10-13 | 2015-10-07 | 4 | RA CAPITAL MANAGEMENT, LLC See Footnote 1 | ACRS | Common Stock | I | 11,0000 | 27 398 | 301 | 2 215 439 | ||||
| 2015-10-13 | 2015-10-07 | 4 | RA CAPITAL MANAGEMENT, LLC See Footnote 1 | ACRS | Common Stock | I | 11,0000 | 1 250 000 | 13 750 | 2 188 041 | ||||
| 2015-10-13 | 2015-10-07 | 4 | RA CAPITAL MANAGEMENT, LLC See Footnote 1 | ACRS | Common Stock | I | 10,6605 | 938 041 | 10 000 | 938 041 | ||||
| 2015-10-09 | 2015-10-07 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P. | ACRS | Common Stock | I | 11,0000 | 285 | 3 | 6 467 | ||||
| 2015-10-09 | 2015-10-07 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P. | ACRS | Common Stock | I | 11,0000 | 13 067 | 144 | 296 739 | ||||
| 2015-10-09 | 2015-10-07 | 4 | CHA ALBERT By funds | ACRS | Common Stock | I | 11,0000 | 13 352 | 147 | 303 206 | ||||
| 2015-10-06 | 3 | Shanler Stuart | ACRS | Common Stock | D | 521 738 | ||||||||
| 2015-10-06 | 3 | Shanler Stuart | ACRS | Common Stock | D | 521 738 | ||||||||
| 2015-10-06 | 3 | Walker Neal | ACRS | Common Stock | D | 1 571 014 | ||||||||
| 2015-10-06 | 3 | Walker Neal | ACRS | Common Stock | D | 1 571 014 | ||||||||
| 2015-10-06 | 3 | Powala Christopher | ACRS | Common Stock | D | 391 302 | ||||||||
| 2015-10-06 | 3 | Powala Christopher | ACRS | Common Stock | D | 391 302 | ||||||||
| 2015-10-06 | 3 | Powala Christopher By Trust | ACRS | Common Stock | I | 391 302 | ||||||||
| 2015-10-06 | 3 | Powala Christopher By Trust | ACRS | Common Stock | I | 391 302 | ||||||||
| 2015-10-06 | 3 | Ruffo Frank | ACRS | Common Stock | D | 260 868 | ||||||||
| 2015-10-06 | 3 | Ruffo Frank | ACRS | Common Stock | D | 260 868 | ||||||||
| 2015-10-06 | 3 | Ali-Jackson Kamil | ACRS | Common Stock | D | 40 578 | ||||||||
| 2015-10-06 | 3 | Ali-Jackson Kamil | ACRS | Common Stock | D | 40 578 | ||||||||
| 2015-10-06 | 3 | Tullman Stephen A. By Trust | ACRS | Common Stock | I | 1 217 391 | ||||||||
| 2015-10-06 | 3 | Tullman Stephen A. By Trust | ACRS | Common Stock | I | 1 217 391 | ||||||||
| 2015-10-06 | 3 | Tullman Stephen A. By NeXeption, LLC | ACRS | Common Stock | I | 1 391 304 | ||||||||
| 2015-10-06 | 3 | Tullman Stephen A. By NeXeption, LLC | ACRS | Common Stock | I | 1 391 304 | ||||||||
| 2015-10-06 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By Vivo Ventures VII Affiliates Fund, L.P. | ACRS | Common Stock | I | 296 036 | ||||||||
| 2015-10-06 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By Vivo Ventures Fund VII, L.P. | ACRS | Common Stock | I | 573 526 | ||||||||
| 2015-10-06 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By Vivo Ventures Fund VII, L.P. | ACRS | Common Stock | I | 573 526 | ||||||||
| 2015-10-06 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By Vivo Ventures Fund VII, L.P. | ACRS | Common Stock | I | 573 526 | ||||||||
| 2015-10-06 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By Vivo Ventures VII Affiliates Fund, L.P. | ACRS | Common Stock | I | 296 036 | ||||||||
| 2015-10-06 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By Vivo Ventures Fund VII, L.P. | ACRS | Common Stock | I | 573 526 | ||||||||
| 2015-10-06 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By Vivo Ventures VII Affiliates Fund, L.P. | ACRS | Common Stock | I | 296 036 | ||||||||
| 2015-10-06 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By Vivo Ventures VII Affiliates Fund, L.P. | ACRS | Common Stock | I | 296 036 | ||||||||
| 2015-10-06 | 3 | CHA ALBERT By Funds | ACRS | Common Stock | I | 579 708 | ||||||||
| 2015-10-06 | 3 | CHA ALBERT By Funds | ACRS | Common Stock | I | 579 708 | ||||||||
| 2015-10-06 | 2015-10-06 | 4 | Bierly Rick | ACRS | Stock Option (right to buy) | D | 11,00 | 17 800 | 17 800 |
P
Открытый рынок или частная покупка непроизводных или производных ценных бумаг
S
Открытый рынок или частная продажа непроизводных или производных ценных бумаг
A
Предоставление, награждение или иное приобретение ценных бумаг у компании (например, опцион)
C
Конвертация производной
D
Продажа или передача ценных бумаг обратно компании
F
Оплата цены исполнения или налогового обязательства с использованием части ценных бумаг, полученных от компании
G
Дарение ценных бумаг инсайдером или ему
K
Обмен акциями и аналогичные операции хеджирования
M
Исполнение или конвертация производных ценных бумаг, полученных от компании (например, опциона)
V
Сделка, добровольно зарегистрированная в Форме 4.
J
Другое (сопровождается сноской с описанием транзакции)
